Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain

Brain Research

Volumn 1296, Issue , 2009, Pages 117-126

  Schuck, Patrícia Fernanda ^a,c   da Costa Ferreira, Gustavo ^a   Tonin, Anelise Miotti ^a   Viegas, Carolina Maso ^a   Busanello, Estela Natacha Brandt ^a   Moura, Alana Pimentel ^a   Zanatta, Ângela ^a   Klamt, Fábio ^a   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Decanoic acid; MCAD deficiency; Mitochondrial function; Octanoic acid; Rat brain

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ATRACTYLOSIDE; CYTOCHROME C; DECANOIC ACID; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; OCTANOIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRIPAMIDE;

ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN MITOCHONDRION; CONTROLLED STUDY; ENERGY METABOLISM; HOMEOSTASIS; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE DEFICIENCY; METABOLIC DISORDER; METABOLITE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RESPIRATION CONTROL; RESPIRATORY CHAIN;

ACYL-COA DEHYDROGENASE; ANIMALS; ATRACTYLOSIDE; BRAIN; CYTOCHROMES C; DECANOIC ACIDS; ELECTRON TRANSPORT; ENZYME INHIBITORS; FATTY ACIDS; HOMEOSTASIS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANES; NADP; OCTANOIC ACIDS; OXYGEN CONSUMPTION; RATS; RATS, WISTAR;

RATTUS;

EID: 70349281392     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.08.053     Document Type: Article

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