Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

Arthritis and Rheumatology

Volumn 68, Issue 11, 2016, Pages 2646-2661

  Maeda, Yuichi ^a,b   Kurakawa, Takashi ^b   Umemoto, Eiji ^a,b   Motooka, Daisuke ^b   Ito, Yoshinaga ^c   Gotoh, Kazuyoshi ^b,d   Hirota, Keiji ^b,c   Matsushita, Masato ^e   Furuta, Yoki ^a,b   Narazaki, Masashi ^b   Sakaguchi, Noriko ^b   Kayama, Hisako ^a,b   Nakamura, Shota ^b   Iida, Tetsuya ^b   Saeki, Yukihiko ^e   Kumanogoh, Atsushi ^a,b   Sakaguchi, Shimon ^a,b,c   Takeda, Kiyoshi ^a,b  

^a JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d OKAYAMA UNIVERSITY   (Japan)

^e MINAMI OSAKA GENERAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; RIBOSOME PROTEIN; RIBOSOME RNA; RNA 16S; ZYMOSAN; AUTOANTIGEN; BACTERIAL DNA; RPL23A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BACTERIAL COLONIZATION; CONTROLLED STUDY; DENDRITIC CELL; DYSBIOSIS; FECES MICROFLORA; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTESTINE FLORA; LYMPH NODE; LYMPHOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RNA SEQUENCE; SPLEEN; T LYMPHOCYTE ACTIVATION; TH17 CELL; AGED; ANIMAL; AUTOIMMUNITY; CASE CONTROL STUDY; CHEMICALLY INDUCED; COLON; EXPERIMENTAL ARTHRITIS; FEMALE; GENETICS; IMMUNOLOGY; INTESTINE; MALE; MICROBIOLOGY; MIDDLE AGED; RHEUMATOID ARTHRITIS; T LYMPHOCYTE;

AGED; ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOANTIGENS; AUTOIMMUNITY; CASE-CONTROL STUDIES; COLON; DNA, BACTERIAL; DYSBIOSIS; FEMALE; GASTROINTESTINAL MICROBIOME; HUMANS; INTERLEUKIN-17; INTESTINES; LYMPH NODES; MALE; MICE; MIDDLE AGED; RIBOSOMAL PROTEINS; RNA, RIBOSOMAL, 16S; SPLEEN; T-LYMPHOCYTES; TH17 CELLS; ZYMOSAN;

EID: 84992549184     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39783     Document Type: Article

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