Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds

Journal of Pharmacological and Toxicological Methods

Volumn 83, Issue , 2017, Pages 72-79

  Terrasso, Ana Paula ^a,b   Silva, Ana Carina ^a,b   Filipe, Augusto ^c   Pedroso, Pedro ^c   Ferreira, Ana Lúcia ^c   Alves, Paula Marques ^a,b   Brito, Catarina ^a,b  

^a INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c Tecnimede Group   (Portugal)

Author keywords

3D co culture; Astrocyte; Human neurotoxicity; In vitro assay; Neuron; Neuroprotection

Indexed keywords

CHLORAMPHENICOL; IDEBENONE; LINEZOLID; NICOTINAMIDE; NEUROPROTECTIVE AGENT;

ARTICLE; ASTROCYTE; AUTOMATION; CELL AGGREGATION; CELL ASSAY; CELL INTERACTION; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; ENERGY METABOLISM; EXTRACELLULAR MATRIX; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MEDICAL DEVICE; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; THREE DIMENSIONAL IMAGING; CELL DIFFERENTIATION; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG EFFECTS; PROCEDURES;

ASTROCYTES; CELL DIFFERENTIATION; CELL SURVIVAL; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; HUMANS; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS;

EID: 84992152168     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2016.10.001     Document Type: Article

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