Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline

Psychopharmacology

Volumn 234, Issue 2, 2017, Pages 293-305

  Openshaw, R L ^a   Thomson, D M ^b   Penninger, J M ^c   Pratt, J A ^b   Morris, B J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^c ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Attention; Cognition; JNK; MAP kinase; MKK7

Indexed keywords

MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; MAP2K7 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7;

ALERTNESS; ANIMAL EXPERIMENT; ARTICLE; ATTENTION DISTURBANCE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG MECHANISM; GENE; GENE EXPRESSION; HAPLOINSUFFICIENCY; HIPPOCAMPUS; MAP2K7 GENE; MOUSE; NEOCORTEX; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; REACTION TIME; RESPONSE TIME; SCHIZOPHRENIA; ANIMAL; ATTENTION; C57BL MOUSE; DECISION MAKING; DEFICIENCY; DRUG EFFECTS; FEMALE; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; PHYSIOLOGY; RISK FACTOR;

ANIMALS; ATTENTION; CHOICE BEHAVIOR; COGNITION; FEMALE; HAPLOINSUFFICIENCY; HUMANS; MALE; MAP KINASE KINASE 7; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MINOCYCLINE; REACTION TIME; RISK FACTORS; SCHIZOPHRENIA;

EID: 84992092879     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-016-4463-y     Document Type: Article

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