Early, untreated Parkinson's disease patients show reaction time variability

Neuroscience Letters

Volumn 441, Issue 1, 2008, Pages 77-80

  Camicioli, Richard M ^a   Wieler, Marguerite ^a   de Frias, Cindy M ^a   Martin, W R Wayne ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Aging; Executive function; Parkinson's disease; Reaction time variability

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HUMAN; MALE; MOTOR PERFORMANCE; PARKINSON DISEASE; PRIORITY JOURNAL; REACTION TIME; RESPONSE TIME; TASK PERFORMANCE;

AGED; ANALYSIS OF VARIANCE; CHOICE BEHAVIOR; FEMALE; HUMANS; INDIVIDUALITY; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE; PROBLEM SOLVING; REACTION TIME;

EID: 46149123640     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.06.004     Document Type: Article

References (23)

1. Ballard C.G., Aarsland D., McKeith I., O'Brien J., Gray A., Cormack F., Burn D., Cassidy T., Starfeldt R., Larsen J.P., Brown R., and Tovee M. Fluctuations in attention: PD dementia vs DLB with parkinsonism. Neurology 59 11 (2002) 1714-1720
2. Baltadjieva R., Giladi N., Gruendlinger L., Peretz C., and Hausdorff J.M. Marked alterations in the gait timing and rhythmicity of patients with de novo Parkinson's disease. Eur. J. Neurosci. 24 6 (2006) 1815-1820
3. Beck A.T., Ward C.H., Mendelson M., Mock J., and Erbaugh J. An inventory for measuring depression. Arch. Gen. Psychiatry 4 (1961) 561-571
4. Blair J.R., and Spreen O. Predicting premorbid IQ: A revision of the National Adult Reading Test. Clin. Neuropsychol. 3 (1989) 129-136
5. Bohnen N.I., Kaufer D.I., Ivanco L.S., Lopresti B., Koeppe R.A., Davis J.G., Mathis C.A., Moore R.Y., and Dekosky S.T. Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study. Arch. Neurol. 60 12 (2003) 1745-1748
6. Burton C.L., Strauss E., Hultsch D.F., Moll A., and Hunter M.A. Intraindividual variability as a marker of neurological dysfunction: a comparison of Alzheimer's Disease and Parkinson's Disease. J. Clin. Exp. Neuropsychol. 28 1 (2006) 67-83
7. Calne D.B., and Lee C. Criteria for diagnosing Parkinson's disease. Ann. Neurol. 32 S1 (1992) S125-S127
8. Camicioli R., Lea E., Nutt J.G., Sexton G., and Oken B.S. Methylphenidate increases the motor effects of L-Dopa in Parkinson's disease: a pilot study. Clin. Neuropharmacol. 24 4 (2001) 208-213
9. Colosimo C., Hughes A.J., Kilford L., and Lees A.J. Lewy body cortical involvement may not always predict dementia in Parkinson's disease. J. Neurol. Neurosurg. Psychiatry 74 7 (2003) 852-856
10. de Frias C.M., Dixon R.A., Fisher N., and Camicioli R. Intraindividual variability in neurocognitive speed: a comparison of Parkinson's disease and normal older adults. Neuropsychologia 45 11 (2007) 2499-2507
11. Dixon R.A., and de Frias CM. The Victoria Longitudinal Study: from characterizing cognitive aging to illustrating changes in memory compensation. Aging Neuropsychol. Cognit. 11 2-3 (2004) 346-376
12. Dixon R.A., Garrett D.D., Lentz T.L., MacDonald S.W.S., Strauss E., and Hultsch D.F. Neurocognitive markers of cognitive impairment: exploring the roles of speed and inconsistency. Neuropsychology 21 3 (2007) 381-399
13. Dubois B., Slachevsky A., Litvan I., and Pillon B. The FAB: a Frontal Assessment Battery at bedside. Neurology 55 11 (2000) 1621-1626
14. Folstein M.F., Folstein S.E., and McHugh P.R. Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12 3 (1975) 189-198
15. Hausdorff J., Doniger G., Springer S., Yogev G., Giladi N., and Simon E. A common cognitive profile in elderly fallers and in patients with Parkinson's Disease: the prominence of impaired executive function and attention. Exp. Aging Res. 32 4 (2006) 411-429
16. Hausdorff J.M., Cudkowicz M.E.C., Firtion R., Wei J.Y., and Goldberger A.L. Gait variability and basal ganglia disorders: stride-to-stride variations of gait cycle timing in Parkinson's disease and Huntington's disease. Mov. Disord. 13 3 (1998) 428-437
17. Martin W.R.W., Wieler M., Stoess A.J., and Schulzer M. Dihydrotetrabenazine positron emission tomography imaging in early, untreated Parkinson's disease. Ann. Neurol. 63 3 (2008) 388-394
18. Reitan R.M., and Wolfson D. Neuroanatomy and Neuropathology (1985), AZ: Neuropsychology Press, Tucson
19. Rowan E., McKeith I.G., Saxby B.K., O'Brien J.T., Burn D., Mosimann U., Newby J., Daniel S., Sanders J., and Wesnes K. Effects of donepezil on central processing speed and attentional measures in Parkinson's disease with dementia and dementia with lewy bodies. Demen. Geriatr. Cognit. Disord. 23 3 (2007) 161-167
20. Sheridan M.R., and Flowers K.A. Movement variability and bradykinesia in Parkinson's disease. Brain 113 4 (1990) 1149-1161
21. van Hilten J., Wagemans E., Ghafoerkhan S., and van Laar T. Movement characteristics in Parkinson's disease: determination of dopaminergic responsiveness and threshold. Clin. Neuropharmacol. 20 5 (1997) 402-408
22. Werheid K., Hoppe C., Thone A., Muller U., Mungersdorf M., and von Cramon D.Y. The Adaptive Digit Ordering Test: clinical application, reliability, and validity of a verbal working memory test. Arch. Clin. Neuropsychol. 17 6 (2002) 547-565
23. Zarow C., Lyness S.A., Mortimer J.A., and Chui H.C. Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. Arch. Neurol. 60 3 (2003) 337-341