Kraepelin and bleuler had it right: People with schizophrenia have deficits sustaining attention over time

Journal of Abnormal Psychology

Volumn 121, Issue 3, 2012, Pages 641-648

  Hahn, Britta ^a   Robinson, Benjamin M ^a   Kaiser, Samuel T ^a   Matveeva, Tatyana M ^a   Harvey, Alexander N ^a   Luck, Steven J ^b   Gold, James M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Performance decrement; Raindrops; Schizophrenia; Sustained attention

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; HALOPERIDOL;

ADULT; ARTICLE; ATTENTION DISTURBANCE; CLINICAL FEATURE; CONSTRUCT VALIDITY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HIT RATE; HUMAN; MALE; NERVE STIMULATION; NERVOUS SYSTEM PARAMETERS; PROBABILITY; REACTION TIME; SCHIZOPHRENIA; SIGNAL DETECTION; TASK PERFORMANCE; TAXONOMY; TREATMENT RESPONSE; VALIDITY; ADOLESCENT; ATTENTION; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; PSYCHOLOGY; VISION;

ADOLESCENT; ADULT; ATTENTION; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PHOTIC STIMULATION; REACTION TIME; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; VISUAL PERCEPTION; YOUNG ADULT;

EID: 84873509172     PISSN: 0021843X     EISSN: 19391846     Source Type: Journal    
DOI: 10.1037/a0028492     Document Type: Article

References (46)

1. Addington, D., Addington, J., Maticka-Tyndale, E., & Joyce, J. (1992). Reliability and validity of a depression rating scale for schizophrenics. Schizophrenia Research, 6, 201-208.
2. American Psychiatric Association. (1994). Diagnostic and Statistical Manual of Mental Disorders (4th ed.). Washington, DC: Author.
3. Andreasen, N. C. (1984). The Scale for the Assessment of Negative Symptoms (SANS). Iowa City, IA: University of Iowa.
4. Andreasen, N. C., Pressler, M., Nopoulos, P., Miller, D., & Ho, B. C. (2010). Antipsychotic dose equivalents and dose-years: A standardized method for comparing exposure to different drugs. Biological Psychiatry, 67, 255-262.
5. Birkett, P., Sigmundsson, T., Sharma, T., Toulopoulou, T., Griffiths, T. D., Reveley, A., & Murray, R. (2007). Reaction time and sustained attention in schizophrenia and its genetic predisposition. Schizophrenia Research, 95, 76-85.
6. Bleuler, E. (1911/1950). Dementia praecox or the group of schizophrenias (J. Zinkin, Trans.). New York, NY: International Universities Press. (Original work published 1911)
7. Buchanan, R. W., Strauss, M. E., Breier, A., Kirkpatrick, B., & Carpenter, W. T., Jr. (1997). Attentional impairments in deficit and nondeficit forms of schizophrenia. The American Journal of Psychiatry, 154, 363-370.
8. Chan, R. C., Wang, Y., Cheung, E. F., Cui, J., Deng, Y., Yuan, Y., & Gong, Q. (2009). Sustained attention deficit along the psychosis proneness continuum: A study on the Sustained Attention to Response Task (SART). Cognitive and Behavioral Neurology, 22, 180-185.
9. Chen, W. J., Liu, S. K., Chang, C. J., Lien, Y. J., Chang, Y. H., & Hwu, H. G. (1998). Sustained attention deficit and schizotypal personality features in nonpsychotic relatives of schizophrenic patients. The American Journal of Psychiatry, 155, 1214-1220.
10. Cornblatt, B. A., & Keilp, J. G. (1994). Impaired attention, genetics, and the pathophysiology of schizophrenia. Schizophrenia Bulletin, 20, 31-46.
11. Cornblatt, B. A., Lenzenweger, M. F., & Erlenmeyer-Kimling, L. (1989). The continuous performance test, identical pairs version: II. Contrasting attentional profiles in schizophrenic and depressed patients. Psychiatry Research, 29, 65-86.
12. Cousineau, D. (2007). Confidence intervals in within-subject designs: A simpler solution to Loftus and Masson's method. Tutorials in Quantitative Methods for Psychology, 1, 42-45.
13. Egan, M. F., Goldberg, T. E., Gscheidle, T., Weirich, M., Bigelow, L. B., & Weinberger, D. R. (2000). Relative risk of attention deficits in siblings of patients with schizophrenia. The American Journal of Psychiatry, 157, 1309-1316.
14. Green, M. F. (1996). What are the functional consequences of neurocognitive deficits in schizophrenia? The American Journal of Psychiatry, 153, 321-330.
15. Hawk, A. B., Carpenter, W. T., Jr., & Strauss, J. S. (1975). Diagnostic criteria and five-year outcome in schizophrenia. A report from the International Pilot Study of schizophrenia. Archives of General Psychiatry, 32, 343-347.
16. Ito, M., Kanno, M., Mori, Y., & Niwa, S. (1997). Attention deficits assessed by Continuous Performance Test and Span of Apprehension Test in Japanese schizophrenic patients. Schizophrenia Research, 23, 205-211.
17. Jones, L. A., Cardno, A. G., Sanders, R. D., Owen, M. J., & Williams, J. (2001). Sustained and selective attention as measures of genetic liability to schizophrenia. Schizophrenia Research, 48, 263-272.
18. Kraepelin, E. (1919). Dementia Praecox and Paraphrenia. Edinburgh, UK: E & S Livingston.
19. Liu, S. K., Hsieh, M. H., Hwang, T. J., Hwu, H. G., Liao, S. C., Lin, S. H., & Chen, W. J. (2006). Re-examining sustained attention deficits as vulnerability indicators for schizophrenia: Stability in the long term course. Journal of Psychiatric Research, 40, 613-621.
20. Mass, R., Wolf, K., Wagner, M., & Haasen, C. (2000). Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test. European Archives of Psychiatry and Clinical Neuroscience, 250, 24-30.
21. Nestor, P. G., Faux, S. F., McCarley, R. W., Sands, S. F., Horvath, T. B., & Peterson, A. (1991). Neuroleptics improve sustained attention in schizophrenia. A study using signal detection theory. Neuropsychopharmacology, 4, 145-149.
22. Nestor, P. G., Faux, S. F., McCarley, R. W., Shenton, M. E., & Sands, S. F. (1990). Measurement of visual sustained attention in schizophrenia using signal detection analysis and a newly developed computerized CPT task. Schizophrenia Research, 3, 329-332.
23. Nuechterlein, K. H. (1983). Signal-detection in vigilance tasks and behavioral-attributes among offspring of schizophrenic mothers and among hyperactive-children. Journal of Abnormal Psychology, 92, 4-28.
24. Nuechterlein, K. H., & Dawson, M. E. (1984). Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophrenia Bulletin, 10, 160-203.
25. Nuechterlein, K. H., Dawson, M. E., & Green, M. F. (1994). Informationprocessing abnormalities as neuropsychological vulnerability indicators for schizophrenia. Acta Psychiatrica Scandinavica Supplementum, 384, 71-79.
26. Nuechterlein, K. H., & Green, M. F. (2006). MATRICS Consensus Cognitive Battery, Manual. Los Angeles, CA: MATRICS Assessment.
27. Nuechterlein, K. H., Parasuraman, R., & Jiang, Q. (1983). Visual sustained attention: Image degradation produces rapid sensitivity decrement over time. Science, 220, 327-329.
28. Obiols, J. E., Clos, M., Corbero, E., Garcia-Domingo, M., de Trincheria, I., & Domenech, E. (1992). Sustained attention deficit in young schizophrenic and schizotypic men. Psychological Reports, 71, 1131-1136.
29. O'Gráda, C., Barry, S., McGlade, N., Behan, C., Haq, F., Hayden, J., & Donohoe, G. (2009). Does the ability to sustain attention underlie symptom severity in schizophrenia? Schizophrenia Research, 107, 319-323.
30. Orzack, M. H., & Kornetsky, C. (1966). Attention dysfunction in chronic schizophrenia. Archives of General Psychiatry, 14, 323-326.
31. Overall, J., & Gorman, D. (1962). The Brief Psychiatric Rating Scale. Psychological Reports, 10, 799-812.
32. Pandurangi, A. K., Sax, K. W., Pelonero, A. L., & Goldberg, S. C. (1994). Sustained attention and positive formal thought disorder in schizophrenia. Schizophrenia Research, 13, 109-116.
33. Parasuraman, R., Warm, J. S., & Dember, W. N. (1987). Vigilance: Taxonomy and utility. In L. S. Mark, J. S. Warm, & R. L. Houston (Eds.), Ergonomics and human factors (pp. 11-39). New York, NY: Springer.
34. Park, S. H., Kim, J. J., Kim, C. H., Kim, J. H., & Lee, K. H. (2011). Sustained attention in the context of emotional processing in patients with schizophrenia. Psychiatry Research, 187, 18-23.
35. Pigache, R. M. (1996). Auditory sustained attention in schizophrenia: A comparison of the Continuous Performance Test and the Pigache Attention Task. Psychiatry Research, 60, 155-165.
36. Pigache, R. M. (1999). Vigilance in schizophrenia and its disruption by impaired pre-attentive selection: A dysintegration hypothesis. Cognitive Neuropsychiatry, 4, 119-144.
37. Rutschmann, J., Cornblatt, B., & Erlenmeyer-Kimling, L. (1977). Sustained attention in children at risk for schizophrenia. Report on a continuous performance test. Archives of General Psychiatry, 34, 571-575.
38. Seidman, L. J., Van Manen, K. J., Turner, W. M., Gamser, D. M., Faraone, S. V., Goldstein, J. M., & Tsuang, M. T. (1998). The effects of increasing resource demand on vigilance performance in adults with schizophrenia or developmental attentional/learning disorders: A preliminary study. Schizophrenia Research, 34, 101-112.
39. Shakow, D. (1962). Segmental set. Archives of General Psychiatry, 6, 1-17.
40. Sponheim, S. R., McGuire, K. A., & Stanwyck, J. J. (2006). Neural anomalies during sustained attention in first-degree biological relatives of schizophrenia patients. Biological Psychiatry, 60, 242-252.
41. Tsuang, H. C., Lin, S. H., Liu, S. K., Hsieh, M. H., Hwang, T. J., Liu, C. M., Chen, W. J. (2006). More severe sustained attention deficits in nonpsychotic siblings of multiplex schizophrenia families than in those of simplex ones. Schizophrenia Research, 87, 172-180.
42. Wang, Q., Chan, R., Sun, J., Yao, J., Deng, W., Sun, X., & Li, T. (2007). Reaction time of the Continuous Performance Test is an endophenotypic marker for schizophrenia: A study of first-episode neuroleptic-naive schizophrenia, their non-psychotic first-degree relatives and healthy population controls. Schizophrenia Research, 89, 293-298.
43. Wechsler, D. (1999). Wechsler Abbreviated Scale of Intelligence (WASI). San Antonio, TX: The Psychological Corporation.
44. Wechsler, D. (2001). Wechsler Test of Adult Reading (WTAR). San Antonio, TX: The Psychological Corporation.
45. Wilkinson, G. S., & Robertson, G. J. (2006). Wide Range Achievement Test (WRAT) 4. Lutz, FL: Psychological Assessment Resources.
46. Wohlberg, G. W., & Kornetsky, C. (1973). Sustained attention in remitted schizophrenics. Archives of General Psychiatry, 28, 533-537.