The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity

BMC Genomics

Volumn 17, Issue 1, 2016, Pages

  Dapprich, Johannes ^a   Ferriola, Deborah ^a,b   Mackiewicz, Kate ^b   Clark, Peter M ^b   Rappaport, Eric ^b   D'Arcy, Monica ^b   Sasson, Ariella ^b   Gai, Xiaowu ^b   Schug, Jonathan ^c   Kaestner, Klaus H ^c   Monos, Dimitri ^b,d  

^a Generation Biotech   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

DNA sequencing; DNA target capture; Genomic resequencing; MHC haplotype; Targeted enrichment

Indexed keywords

NUCLEOTIDE; OLIGONUCLEOTIDE; PRIMER DNA;

ARTICLE; BIOTINYLATION; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA FRAGMENTATION; DNA SEQUENCE; GENETIC VARIATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NEXT GENERATION SEQUENCING; NUCLEIC ACID ANALYSIS; SEQUENCE ANALYSIS; GENETIC DATABASE; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; NUCLEIC ACID HYBRIDIZATION; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION;

COMPARATIVE GENOMIC HYBRIDIZATION; DATABASES, GENETIC; DNA PRIMERS; GENETIC VARIATION; GENOME, HUMAN; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; NUCLEIC ACID HYBRIDIZATION; REAL-TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 84991800774     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-016-2836-6     Document Type: Article

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