-
1
-
-
84886837226
-
The role of antioxidants in the pathophysiology, complications, and management of diabetes mellitus
-
Zatalia SR and Sanusi H. The role of antioxidants in the pathophysiology, complications, and management of diabetes mellitus. Acta medica Indonesiana. 2013; 45:141-147.
-
(2013)
Acta medica Indonesiana
, vol.45
, pp. 141-147
-
-
Zatalia, S.R.1
Sanusi, H.2
-
3
-
-
67650607711
-
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension
-
van Heerebeek L, Hamdani N, Handoko ML, Falcao-Pires I, Musters RJ, Kupreishvili K, Ijsselmuiden AJ, Schalkwijk CG, Bronzwaer JG, Diamant M, Borbely A, van der Velden J, Stienen GJ, Laarman GJ, Niessen HW and Paulus WJ. Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation. 2008; 117:43-51.
-
(2008)
Circulation
, vol.117
, pp. 43-51
-
-
van Heerebeek, L.1
Hamdani, N.2
Handoko, M.L.3
Falcao-Pires, I.4
Musters, R.J.5
Kupreishvili, K.6
Ijsselmuiden, A.J.7
Schalkwijk, C.G.8
Bronzwaer, J.G.9
Diamant, M.10
Borbely, A.11
van der Velden, J.12
Stienen, G.J.13
Laarman, G.J.14
Niessen, H.W.15
Paulus, W.J.16
-
5
-
-
84900428277
-
High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy
-
Bugyei-Twum A, Advani A, Advani SL, Zhang Y, Thai K, Kelly DJ and Connelly KA. High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy. Cardiovascular diabetology. 2014; 13:89.
-
(2014)
Cardiovascular diabetology
, vol.13
, pp. 89
-
-
Bugyei-Twum, A.1
Advani, A.2
Advani, S.L.3
Zhang, Y.4
Thai, K.5
Kelly, D.J.6
Connelly, K.A.7
-
6
-
-
34250215301
-
High glucose promotes the production of collagen types I and III by cardiac fibroblasts through a pathway dependent on extracellular-signal-regulated kinase 1/2
-
Tang M, Zhang W, Lin H, Jiang H, Dai H and Zhang Y. High glucose promotes the production of collagen types I and III by cardiac fibroblasts through a pathway dependent on extracellular-signal-regulated kinase 1/2. Molecular and cellular biochemistry. 2007; 301:109-114.
-
(2007)
Molecular and cellular biochemistry
, vol.301
, pp. 109-114
-
-
Tang, M.1
Zhang, W.2
Lin, H.3
Jiang, H.4
Dai, H.5
Zhang, Y.6
-
7
-
-
73449146238
-
Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis
-
Zhao L, Wang X, Chang Q, Xu J, Huang Y, Guo Q, Zhang S, Wang W, Chen X and Wang J. Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. European journal of pharmacology. 2010; 627:304-312.
-
(2010)
European journal of pharmacology
, vol.627
, pp. 304-312
-
-
Zhao, L.1
Wang, X.2
Chang, Q.3
Xu, J.4
Huang, Y.5
Guo, Q.6
Zhang, S.7
Wang, W.8
Chen, X.9
Wang, J.10
-
8
-
-
0036903858
-
Cardiovascular pharmacological effects of bisbenzylisoquinoline alkaloid derivatives
-
Qian JQ. Cardiovascular pharmacological effects of bisbenzylisoquinoline alkaloid derivatives. Acta pharmacologica Sinica. 2002; 23:1086-1092.
-
(2002)
Acta pharmacologica Sinica
, vol.23
, pp. 1086-1092
-
-
Qian, J.Q.1
-
9
-
-
84883830422
-
Neferine exerts its antithrombotic effect by inhibiting platelet aggregation and promoting dissociation of platelet aggregates
-
Zhou YJ, Xiang JZ, Yuan H, Liu H, Tang Q, Hao HZ, Yin Z, Wang J and Ming ZY. Neferine exerts its antithrombotic effect by inhibiting platelet aggregation and promoting dissociation of platelet aggregates. Thrombosis research. 2013; 132:202-210.
-
(2013)
Thrombosis research
, vol.132
, pp. 202-210
-
-
Zhou, Y.J.1
Xiang, J.Z.2
Yuan, H.3
Liu, H.4
Tang, Q.5
Hao, H.Z.6
Yin, Z.7
Wang, J.8
Ming, Z.Y.9
-
10
-
-
77956914527
-
Anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ChEs and BACE1
-
Jung HA, Jin SE, Choi RJ, Kim DH, Kim YS, Ryu JH, Kim DW, Son YK, Park JJ and Choi JS. Anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ChEs and BACE1. Life sciences. 2010; 87:420-430.
-
(2010)
Life sciences
, vol.87
, pp. 420-430
-
-
Jung, H.A.1
Jin, S.E.2
Choi, R.J.3
Kim, D.H.4
Kim, Y.S.5
Ryu, J.H.6
Kim, D.W.7
Son, Y.K.8
Park, J.J.9
Choi, J.S.10
-
11
-
-
56249128940
-
Effects of extracts and neferine from the embryo of Nelumbo nucifera seeds on the central nervous system
-
Sugimoto Y, Furutani S, Itoh A, Tanahashi T, Nakajima H, Oshiro H, Sun S and Yamada J. Effects of extracts and neferine from the embryo of Nelumbo nucifera seeds on the central nervous system. Phytomedicine. 2008; 15:1117-1124.
-
(2008)
Phytomedicine
, vol.15
, pp. 1117-1124
-
-
Sugimoto, Y.1
Furutani, S.2
Itoh, A.3
Tanahashi, T.4
Nakajima, H.5
Oshiro, H.6
Sun, S.7
Yamada, J.8
-
12
-
-
84953237020
-
Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/JNK activation
-
Xu L, Zhang X, Li Y, Lu S, Lu S, Li J, Wang Y, Tian X, Wei JJ, Shao C and Liu Z. Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/JNK activation. Tumour Biol. 2016; 37:8721-8729.
-
(2016)
Tumour Biol
, vol.37
, pp. 8721-8729
-
-
Xu, L.1
Zhang, X.2
Li, Y.3
Lu, S.4
Lu, S.5
Li, J.6
Wang, Y.7
Tian, X.8
Wei, J.J.9
Shao, C.10
Liu, Z.11
-
13
-
-
84894081770
-
Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest
-
Poornima P, Weng CF and Padma VV. Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest. BioFactors. 2014; 40:121-131.
-
(2014)
BioFactors
, vol.40
, pp. 121-131
-
-
Poornima, P.1
Weng, C.F.2
Padma, V.V.3
-
14
-
-
84880773508
-
Neferine isolated from Nelumbo nucifera enhances anti-cancer activities in Hep3B cells: molecular mechanisms of cell cycle arrest, ER stress induced apoptosis and anti-angiogenic response
-
Yoon JS, Kim HM, Yadunandam AK, Kim NH, Jung HA, Choi JS, Kim CY and Kim GD. Neferine isolated from Nelumbo nucifera enhances anti-cancer activities in Hep3B cells: molecular mechanisms of cell cycle arrest, ER stress induced apoptosis and anti-angiogenic response. Phytomedicine. 2013; 20:1013-1022.
-
(2013)
Phytomedicine
, vol.20
, pp. 1013-1022
-
-
Yoon, J.S.1
Kim, H.M.2
Yadunandam, A.K.3
Kim, N.H.4
Jung, H.A.5
Choi, J.S.6
Kim, C.Y.7
Kim, G.D.8
-
15
-
-
36048980873
-
Relaxation mechanisms of neferine on the rabbit corpus cavernosum tissue in vitro
-
Chen J, Qi J, Chen F, Liu JH, Wang T, Yang J and Yin CP. Relaxation mechanisms of neferine on the rabbit corpus cavernosum tissue in vitro. Asian journal of andrology. 2007; 9:795-800.
-
(2007)
Asian journal of andrology
, vol.9
, pp. 795-800
-
-
Chen, J.1
Qi, J.2
Chen, F.3
Liu, J.H.4
Wang, T.5
Yang, J.6
Yin, C.P.7
-
16
-
-
84879823286
-
Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice
-
Niu CH, Wang Y, Liu JD, Wang JL and Xiao JH. Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. European journal of pharmacology. 2013; 714:112-119.
-
(2013)
European journal of pharmacology
, vol.714
, pp. 112-119
-
-
Niu, C.H.1
Wang, Y.2
Liu, J.D.3
Wang, J.L.4
Xiao, J.H.5
-
17
-
-
84928383923
-
Anti-fibrotic effects of neferine on carbon tetrachlorideinduced hepatic fibrosis in mice
-
Chen MS, Zhang JH, Wang JL, Gao L, Chen XX and Xiao JH. Anti-fibrotic effects of neferine on carbon tetrachlorideinduced hepatic fibrosis in mice. The American journal of Chinese medicine. 2015; 43:231-240.
-
(2015)
The American journal of Chinese medicine
, vol.43
, pp. 231-240
-
-
Chen, M.S.1
Zhang, J.H.2
Wang, J.L.3
Gao, L.4
Chen, X.X.5
Xiao, J.H.6
-
18
-
-
84893103006
-
Investigational drugs targeting cardiac fibrosis
-
Roubille F, Busseuil D, Merlet N, Kritikou EA, Rheaume E and Tardif JC. Investigational drugs targeting cardiac fibrosis. Expert review of cardiovascular therapy. 2014; 12:111-125.
-
(2014)
Expert review of cardiovascular therapy
, vol.12
, pp. 111-125
-
-
Roubille, F.1
Busseuil, D.2
Merlet, N.3
Kritikou, E.A.4
Rheaume, E.5
Tardif, J.C.6
-
19
-
-
72249102361
-
Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes
-
Ares-Carrasco S, Picatoste B, Benito-Martin A, Zubiri I, Sanz AB, Sanchez-Nino MD, Ortiz A, Egido J, Tunon J and Lorenzo O. Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes. American journal of physiology Heart and circulatory physiology. 2009; 297:H2109-2119.
-
(2009)
American journal of physiology Heart and circulatory physiology
, vol.297
, pp. H2109-H2119
-
-
Ares-Carrasco, S.1
Picatoste, B.2
Benito-Martin, A.3
Zubiri, I.4
Sanz, A.B.5
Sanchez-Nino, M.D.6
Ortiz, A.7
Egido, J.8
Tunon, J.9
Lorenzo, O.10
-
20
-
-
33645280925
-
Diabetic cardiomyopathy: the search for a unifying hypothesis
-
Poornima IG, Parikh P and Shannon RP. Diabetic cardiomyopathy: the search for a unifying hypothesis. Circulation research. 2006; 98:596-605.
-
(2006)
Circulation research
, vol.98
, pp. 596-605
-
-
Poornima, I.G.1
Parikh, P.2
Shannon, R.P.3
-
21
-
-
84951268742
-
Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation
-
Buahorm S, Puthong S, Palaga T, Lirdprapamongkol K, Phuwapraisirisan P, Svasti J and Chanchao C. Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation. Daru. 2015; 23:55.
-
(2015)
Daru
, vol.23
, pp. 55
-
-
Buahorm, S.1
Puthong, S.2
Palaga, T.3
Lirdprapamongkol, K.4
Phuwapraisirisan, P.5
Svasti, J.6
Chanchao, C.7
-
22
-
-
67649424560
-
p21 in cancer: intricate networks and multiple activities
-
Abbas T and Dutta A. p21 in cancer: intricate networks and multiple activities. Nature reviews Cancer. 2009; 9:400-414.
-
(2009)
Nature reviews Cancer
, vol.9
, pp. 400-414
-
-
Abbas, T.1
Dutta, A.2
-
23
-
-
27644456575
-
NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts
-
Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S and Sorescu D. NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circulation research. 2005; 97:900-907.
-
(2005)
Circulation research
, vol.97
, pp. 900-907
-
-
Cucoranu, I.1
Clempus, R.2
Dikalova, A.3
Phelan, P.J.4
Ariyan, S.5
Dikalov, S.6
Sorescu, D.7
-
24
-
-
84939790154
-
Lefty-1 alleviates TGF-beta1-induced fibroblastmyofibroblast transdifferentiation in NRK-49F cells
-
Zhang L, Zhang J, Xu C, Zhou X, Wang W, Zheng R, Hu W and Wu P. Lefty-1 alleviates TGF-beta1-induced fibroblastmyofibroblast transdifferentiation in NRK-49F cells. Drug design, development and therapy. 2015; 9:4669-4678.
-
(2015)
Drug design, development and therapy
, vol.9
, pp. 4669-4678
-
-
Zhang, L.1
Zhang, J.2
Xu, C.3
Zhou, X.4
Wang, W.5
Zheng, R.6
Hu, W.7
Wu, P.8
-
25
-
-
84903267895
-
Hyperglycemia enhances function and differentiation of adult rat cardiac fibroblasts
-
Shamhart PE, Luther DJ, Adapala RK, Bryant JE, Petersen KA, Meszaros JG and Thodeti CK. Hyperglycemia enhances function and differentiation of adult rat cardiac fibroblasts. Canadian journal of physiology and pharmacology. 2014; 92:598-604.
-
(2014)
Canadian journal of physiology and pharmacology
, vol.92
, pp. 598-604
-
-
Shamhart, P.E.1
Luther, D.J.2
Adapala, R.K.3
Bryant, J.E.4
Petersen, K.A.5
Meszaros, J.G.6
Thodeti, C.K.7
-
26
-
-
34047182621
-
TGFbeta, cardiac fibroblasts, and the fibrotic response
-
Leask A. TGFbeta, cardiac fibroblasts, and the fibrotic response. Cardiovascular research. 2007; 74:207-212.
-
(2007)
Cardiovascular research
, vol.74
, pp. 207-212
-
-
Leask, A.1
-
28
-
-
78649984380
-
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
-
Rajesh M, Mukhopadhyay P, Batkai S, Patel V, Saito K, Matsumoto S, Kashiwaya Y, Horvath B, Mukhopadhyay B, Becker L, Hasko G, Liaudet L, Wink DA, Veves A, Mechoulam R and Pacher P. Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. Journal of the American College of Cardiology. 2010; 56:2115-2125.
-
(2010)
Journal of the American College of Cardiology
, vol.56
, pp. 2115-2125
-
-
Rajesh, M.1
Mukhopadhyay, P.2
Batkai, S.3
Patel, V.4
Saito, K.5
Matsumoto, S.6
Kashiwaya, Y.7
Horvath, B.8
Mukhopadhyay, B.9
Becker, L.10
Hasko, G.11
Liaudet, L.12
Wink, D.A.13
Veves, A.14
Mechoulam, R.15
Pacher, P.16
-
29
-
-
84860524460
-
Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF beta/Smad activation and cardiac fibrosis induced by angiotensin II
-
Ma F, Li Y, Jia L, Han Y, Cheng J, Li H, Qi Y and Du J. Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF beta/Smad activation and cardiac fibrosis induced by angiotensin II. PloS one. 2012; 7:e35144.
-
(2012)
PloS one
, vol.7
-
-
Ma, F.1
Li, Y.2
Jia, L.3
Han, Y.4
Cheng, J.5
Li, H.6
Qi, Y.7
Du, J.8
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