Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation

DARU, Journal of Pharmaceutical Sciences

Volumn 23, Issue 1, 2015, Pages

  Buahorm, Sureerat ^a   Puthong, Songchan ^a   Palaga, Tanapat ^a   Lirdprapamongkol, Kriengsak ^b   Phuwapraisirisan, Preecha ^a   Svasti, Jisnuson ^b   Chanchao, Chanpen ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b Krung Thep Maha Nakhon   (Thailand)

Author keywords

Apis mellifera; Cardanol; Cell arrest; Cell death; p21; Propolis

Indexed keywords

CARDANOL; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; DEATH RECEPTOR 5; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE; PHENOL DERIVATIVE; PROPOLIS; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P21; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

APIS MELLIFERA; APOPTOSIS; ARTICLE; BCL 2 GENE; BREAST CANCER; C FLIPP GENE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL DEATH; CONTROLLED STUDY; DR5 GENE; DRUG CYTOTOXICITY; G1 PHASE CELL CYCLE CHECKPOINT; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MADD GENE; MCL 1 GENE; NONHUMAN; PROTEIN EXPRESSION; THAILAND; UPREGULATION; ANIMAL; BEE; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BEES; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOXORUBICIN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PHENOLS;

EID: 84951268742     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/s40199-015-0138-1     Document Type: Article

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