Development, optimization and characterization of glycyrrhetinic acid–chitosan nanoparticles of atorvastatin for liver targeting

Drug Delivery

Volumn 23, Issue 7, 2016, Pages 2290-2297

  Rohilla, Raman ^a   Garg, Tarun ^a   Bariwal, Jitender ^a   Goyal, Amit K ^a   Rath, Goutam ^a  

^a ISF COLLEGE OF PHARMACY   (India)

Author keywords

Atorvastatin; drug delivery; glycyrrhetinic acid modified chitosan; liver targeting; nanoparticles

Indexed keywords

ATORVASTATIN; CHITOSAN NANOPARTICLE; GLYCYRRHETINIC ACID; CHITOSAN; DRUG CARRIER; NANOPARTICLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RELEASE; DRUG SYNTHESIS; DRUG TARGETING; INFRARED SPECTROSCOPY; LIVER; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; CHEMISTRY; DRUG EFFECTS; HEP-G2 CELL LINE; HUMAN; MEDICINAL CHEMISTRY; PROCEDURES; TUMOR CELL LINE;

ATORVASTATIN CALCIUM; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GLYCYRRHETINIC ACID; HEP G2 CELLS; HUMANS; LIVER; NANOPARTICLES; PARTICLE SIZE;

EID: 84991720153     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2014.977460     Document Type: Article

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