IFN-γ Induces Histone 3 Lysine 27 Trimethylation in a Small Subset of Promoters to Stably Silence Gene Expression in Human Macrophages

Cell Reports

Volumn 16, Issue 12, 2016, Pages 3121-3129

  Qiao, Yu ^a   Kang, Kyuho ^a   Giannopoulou, Eugenia ^a,b   Fang, Celeste ^a   Ivashkiv, Lionel B ^a,c  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b NEW YORK CITY COLLEGE OF TECHNOLOGY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; GAMMA INTERFERON; HISTONE H3; INTERLEUKIN 4; LYSINE; TRANSCRIPTION FACTOR EZH2; EZH2 PROTEIN, HUMAN; HISTONE;

ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE; GENE EXPRESSION; GENE FUNCTION; GENE REPRESSION; GENE SILENCING; GENETIC STABILITY; GENETIC TRANSCRIPTION; HISTONE METHYLATION; HUMAN; HUMAN CELL; MACROPHAGE; MERTK GENE; OSTEOCLAST; PPARG GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RANK GENE; REGULATORY MECHANISM; RNA SEQUENCE; SIGNAL TRANSDUCTION; BIOSYNTHESIS; DNA METHYLATION; GENETICS; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; PHYSIOLOGY;

DNA METHYLATION; ENHANCER OF ZESTE HOMOLOG 2 PROTEIN; GENE SILENCING; HISTONES; HUMANS; INTERFERON-GAMMA; LYSINE; MACROPHAGE ACTIVATION; MACROPHAGES; PROMOTER REGIONS, GENETIC;

EID: 84991660891     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.051     Document Type: Article

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