VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

EMBO Journal

Volumn 36, Issue 2, 2017, Pages 135-150

  Papadopoulos, Chrisovalantis ^a   Kirchner, Philipp ^a   Bug, Monika ^a   Grum, Daniel ^a   Koerver, Lisa ^a   Schulze, Nina ^a   Poehler, Robert ^a   Dressler, Alina ^a   Fengler, Sven ^a   Arhzaouy, Khalid ^b   Lux, Vanda ^a   Ehrmann, Michael ^a   Weihl, Conrad C ^b   Meyer, Hemmo ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AAA+ type ATPase; autophagy; lysosomal membrane permeabilization; multisystem proteinopathy 1; ubiquitin

Indexed keywords

GALECTIN 3; PLAA PROTEIN; PROTEIN; PROTEIN P97; UBXD1 PROTEIN; UNCLASSIFIED DRUG; YOD1 PROTEIN; ADENOSINE TRIPHOSPHATASE; CARRIER PROTEIN; CDC48 PROTEIN; CELL CYCLE PROTEIN; PHOSPHOLIPASE A2-ACTIVATING PROTEIN; PROTEINASE; THIOL ESTER HYDROLASE; UBXD1 PROTEIN, HUMAN; YOD1 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENDOSOME; FEMALE; GENE MUTATION; HEK293 CELL LINE; HELA CELL LINE; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; NERVE DEGENERATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; ANIMAL; CELL CULTURE; METABOLISM; MOUSE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; AUTOPHAGY; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELLS, CULTURED; ENDOPEPTIDASES; HUMANS; LYSOSOMES; MICE; PROTEINS; THIOLESTER HYDROLASES;

EID: 84991648582     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201695148     Document Type: Article

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