메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

FOXA and master transcription factors recruit Mediator and Cohesin to the core transcriptional regulatory circuitry of cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; COHESIN; FOXA1 PROTEIN, HUMAN; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; MEDIATOR COMPLEX; NONHISTONE PROTEIN;

EID: 84991625009     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep34962     Document Type: Article
Times cited : (36)

References (60)
  • 1
    • 84865249952 scopus 로고    scopus 로고
    • Transcription factors: From enhancer binding to developmental control
    • Spitz, F., Furlong, E. E. M. Transcription factors: from enhancer binding to developmental control. Nat. Rev. Genet. 13, 613-626 (2012).
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 613-626
    • Spitz, F.1    Furlong, E.E.M.2
  • 2
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch, R., Young, R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132, 567-582 (2008).
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 3
    • 71449125977 scopus 로고    scopus 로고
    • Forcing cells to change lineages
    • Graf, T., Enver, T. Forcing cells to change lineages. Nature 462, 587-594 (2009).
    • (2009) Nature , vol.462 , pp. 587-594
    • Graf, T.1    Enver, T.2
  • 4
    • 84872019812 scopus 로고    scopus 로고
    • A blueprint for engineering cell fate: Current technologies to reprogram cell identity
    • Morris, S. A., Daley, G. Q. A blueprint for engineering cell fate: current technologies to reprogram cell identity. Cell Res. 23, 33-48 (2013).
    • (2013) Cell Res. , vol.23 , pp. 33-48
    • Morris, S.A.1    Daley, G.Q.2
  • 5
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis, R. L., Weintraub, H., Lassar, A. B. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51, 987-1000 (1987).
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 6
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K., Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006).
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 8
    • 84875198920 scopus 로고    scopus 로고
    • Transcriptional regulation and its misregulation in disease
    • Lee, T. I., Young, R. A. Transcriptional regulation and its misregulation in disease. Cell 152, 1237-1251 (2013).
    • (2013) Cell , vol.152 , pp. 1237-1251
    • Lee, T.I.1    Young, R.A.2
  • 9
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer, L. A. et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122, 947-956 (2005).
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1
  • 10
    • 0024406874 scopus 로고
    • Positive autoregulation of the myogenic determination gene MyoD1
    • Thayer, M. J. et al. Positive autoregulation of the myogenic determination gene MyoD1. Cell 58, 241-248 (1989).
    • (1989) Cell , vol.58 , pp. 241-248
    • Thayer, M.J.1
  • 11
    • 84961289604 scopus 로고    scopus 로고
    • Pioneer transcription factors, chromatin dynamics, cell fate control
    • Zaret, K. S., Mango, S. E. Pioneer transcription factors, chromatin dynamics, cell fate control. Curr. Opin. Genet. Dev. 37, 76-81 (2016).
    • (2016) Curr. Opin. Genet. Dev. , vol.37 , pp. 76-81
    • Zaret, K.S.1    Mango, S.E.2
  • 12
    • 84937532893 scopus 로고    scopus 로고
    • Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming
    • Soufi, A. et al. Pioneer Transcription Factors Target Partial DNA Motifs on Nucleosomes to Initiate Reprogramming. Cell 161, 555-568 (2015).
    • (2015) Cell , vol.161 , pp. 555-568
    • Soufi, A.1
  • 13
    • 84926180401 scopus 로고    scopus 로고
    • Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates
    • Wang, A. et al. Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates. Cell Stem Cell 16, 386-399 (2015).
    • (2015) Cell Stem Cell , vol.16 , pp. 386-399
    • Wang, A.1
  • 14
    • 22144486551 scopus 로고    scopus 로고
    • Chromosome-wide mapping of estrogen receptor binding reveals long-Range regulation requiring the forkhead protein FoxA1
    • Carroll, J. S. et al. Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1. Cell 122, 33-43 (2005).
    • (2005) Cell , vol.122 , pp. 33-43
    • Carroll, J.S.1
  • 15
    • 0032450899 scopus 로고    scopus 로고
    • Role of general and gene-specific cofactors in the regulation of eukaryotic transcription
    • Roeder, R. G. Role of General and Gene-specific Cofactors in the Regulation of Eukaryotic Transcription. Cold Spring Harb. Symp. Quant. Biol. 63, 201-218 (1998).
    • (1998) Cold Spring Harb. Symp. Quant. Biol. , vol.63 , pp. 201-218
    • Roeder, R.G.1
  • 16
    • 84871699564 scopus 로고    scopus 로고
    • Promoter-proximal pausing of RNA polymerase II: Emerging roles in metazoans
    • Adelman, K., Lis, J. T. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat. Rev. Genet. 13, 720-731 (2012).
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 720-731
    • Adelman, K.1    Lis, J.T.2
  • 17
    • 84861857476 scopus 로고    scopus 로고
    • RNA Polymerase II elongation control
    • Zhou, Q., Li, T., Price, D. H. RNA Polymerase II Elongation Control. Annu. Rev. Biochem. 81, 119-143 (2012).
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 119-143
    • Zhou, Q.1    Li, T.2    Price, D.H.3
  • 18
    • 77958111633 scopus 로고    scopus 로고
    • The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
    • Malik, S., Roeder, R. G. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat. Rev. Genet. 11, 761-772 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 761-772
    • Malik, S.1    Roeder, R.G.2
  • 19
    • 73349127026 scopus 로고    scopus 로고
    • Cohesin: Its roles and mechanisms
    • Nasmyth, K., Haering, C. H. Cohesin: Its Roles and Mechanisms. Annu. Rev. Genet. 43, 525-558 (2009).
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 525-558
    • Nasmyth, K.1    Haering, C.H.2
  • 20
    • 77957139539 scopus 로고    scopus 로고
    • Mediator and cohesin connect gene expression and chromatin architecture
    • Kagey, M. H. et al. Mediator and cohesin connect gene expression and chromatin architecture. Nature 467, 430-435 (2010).
    • (2010) Nature , vol.467 , pp. 430-435
    • Kagey, M.H.1
  • 21
    • 77951920690 scopus 로고    scopus 로고
    • C-Myc regulates transcriptional pause release
    • Rahl, P. B. et al. c-Myc regulates transcriptional pause release. Cell 141, 432-445 (2010).
    • (2010) Cell , vol.141 , pp. 432-445
    • Rahl, P.B.1
  • 22
  • 23
    • 84956634373 scopus 로고    scopus 로고
    • Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
    • Zhang, X. et al. Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. Nat. Genet. 48, 176-182 (2016).
    • (2016) Nat. Genet. , vol.48 , pp. 176-182
    • Zhang, X.1
  • 24
    • 84897459814 scopus 로고    scopus 로고
    • An atlas of active enhancers across human cell types and tissues
    • Andersson, R. et al. An atlas of active enhancers across human cell types and tissues. Nature 507, 455-461 (2014).
    • (2014) Nature , vol.507 , pp. 455-461
    • Andersson, R.1
  • 25
    • 84888015137 scopus 로고    scopus 로고
    • Super-Enhancers in the Control of Cell Identity and Disease
    • Hnisz, D. et al. Super-Enhancers in the Control of Cell Identity and Disease. Cell 155, 934-947 (2013).
    • (2013) Cell , vol.155 , pp. 934-947
    • Hnisz, D.1
  • 26
    • 84876222028 scopus 로고    scopus 로고
    • Selective inhibition of tumor oncogenes by disruption of super-enhancers
    • Lovén, J. et al. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell 153, 320-334 (2013).
    • (2013) Cell , vol.153 , pp. 320-334
    • Lovén, J.1
  • 27
    • 84944906185 scopus 로고    scopus 로고
    • Directly targeting transcriptional dysregulation in cancer
    • Gonda, T. J., Ramsay, R. G. Directly targeting transcriptional dysregulation in cancer. Nat. Rev. Cancer 15, 686-694 (2015).
    • (2015) Nat. Rev. Cancer , vol.15 , pp. 686-694
    • Gonda, T.J.1    Ramsay, R.G.2
  • 28
    • 84901419546 scopus 로고    scopus 로고
    • Cohesin in cancer: Chromosome segregation and beyond
    • Losada, A. Cohesin in cancer: chromosome segregation and beyond. Nat. Rev. Cancer 14, 389-393 (2014).
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 389-393
    • Losada, A.1
  • 30
    • 39149121436 scopus 로고    scopus 로고
    • Cohesin mediates transcriptional insulation by CCCTC-binding factor
    • Wendt, K. S. et al. Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature 451, 796-801 (2008).
    • (2008) Nature , vol.451 , pp. 796-801
    • Wendt, K.S.1
  • 31
    • 38849121606 scopus 로고    scopus 로고
    • Cohesins functionally associate with CTCF on Mammalian chromosome arms
    • Parelho, V. et al. Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms. Cell 132, 422-433 (2008).
    • (2008) Cell , vol.132 , pp. 422-433
    • Parelho, V.1
  • 32
    • 84923362619 scopus 로고    scopus 로고
    • Integrative analysis of 111 reference human epigenomes
    • Kundaje, A. et al. Integrative analysis of 111 reference human epigenomes. Nature 518, 317-330 (2015).
    • (2015) Nature , vol.518 , pp. 317-330
    • Kundaje, A.1
  • 33
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst, J. et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49 (2011).
    • (2011) Nature , vol.473 , pp. 43-49
    • Ernst, J.1
  • 34
    • 84865836579 scopus 로고    scopus 로고
    • Widespread plasticity in CTCF occupancy linked to DNA methylation
    • Wang, H. et al. Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res. 22, 1680-1688 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1680-1688
    • Wang, H.1
  • 35
    • 84916897361 scopus 로고    scopus 로고
    • Enhancer activation requires trans-recruitment of a mega transcription factor complex
    • Liu, Z. et al. Enhancer Activation Requires trans-Recruitment of a Mega Transcription Factor Complex. Cell 159, 358-373 (2014).
    • (2014) Cell , vol.159 , pp. 358-373
    • Liu, Z.1
  • 36
    • 10744227070 scopus 로고    scopus 로고
    • Control of pancreas and liver gene expression by HNF transcription factors
    • Odom, D. T. et al. Control of pancreas and liver gene expression by HNF transcription factors. Science 303, 1378-1381 (2004).
    • (2004) Science , vol.303 , pp. 1378-1381
    • Odom, D.T.1
  • 37
    • 0034617082 scopus 로고    scopus 로고
    • Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex
    • Burakov, D., Wong, C. W., Rachez, C., Cheskis, B. J., Freedman, L. P. Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex. J. Biol. Chem. 275, 20928-20934 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 20928-20934
    • Burakov, D.1    Wong, C.W.2    Rachez, C.3    Cheskis, B.J.4    Freedman, L.P.5
  • 38
    • 0036019471 scopus 로고    scopus 로고
    • Polyamines modulate the interaction between nuclear receptors and Vitamin D receptor-interacting protein 205
    • Maeda, Y. et al. Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205. Mol. Endocrinol. 16, 1502-1510 (2002).
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1502-1510
    • Maeda, Y.1
  • 39
    • 0036318299 scopus 로고    scopus 로고
    • TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4
    • Malik, S., Wallberg, A. E., Kang, Y. K., Roeder, R. G. TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4. Mol. Cell. Biol. 22, 5626-5637 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5626-5637
    • Malik, S.1    Wallberg, A.E.2    Kang, Y.K.3    Roeder, R.G.4
  • 40
    • 84879695128 scopus 로고    scopus 로고
    • Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
    • Li, W. et al. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature 498, 516-520 (2013).
    • (2013) Nature , vol.498 , pp. 516-520
    • Li, W.1
  • 41
    • 75649116449 scopus 로고    scopus 로고
    • Molecular interactions between HNF4a FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing
    • Wallerman, O. et al. Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res. 37, 7498-7508 (2009).
    • (2009) Nucleic Acids Res. , vol.37 , pp. 7498-7508
    • Wallerman, O.1
  • 42
    • 84907996370 scopus 로고    scopus 로고
    • Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation
    • Alder, O. et al. Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation. Cell Rep. 9, 261-271 (2014).
    • (2014) Cell Rep. , vol.9 , pp. 261-271
    • Alder, O.1
  • 43
    • 84878273239 scopus 로고    scopus 로고
    • Induction of pluripotency in mouse somatic cells with lineage specifiers
    • Shu, J. et al. Induction of pluripotency in mouse somatic cells with lineage specifiers. Cell 153, 963-975 (2013).
    • (2013) Cell , vol.153 , pp. 963-975
    • Shu, J.1
  • 44
    • 84945487712 scopus 로고    scopus 로고
    • The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis
    • Pomerantz, M. M. et al. The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. Nat. Genet. 47, 1346-1351 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 1346-1351
    • Pomerantz, M.M.1
  • 45
    • 78651250284 scopus 로고    scopus 로고
    • FOXA1 is a key determinant of estrogen receptor function and endocrine response
    • Hurtado, A., Holmes, K. a, Ross-Innes, C. S., Schmidt, D., Carroll, J. S. FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat. Genet. 43, 27-33 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 27-33
    • Hurtado, A.1    Holmes, K.A.2    Ross-Innes, C.S.3    Schmidt, D.4    Carroll, J.S.5
  • 46
    • 84910618431 scopus 로고    scopus 로고
    • FOSL2 Positively regulates TGF-1 Signalling in non-small cell lung cancer
    • Wang, J. et al. FOSL2 Positively Regulates TGF-1 Signalling in Non-Small Cell Lung Cancer. PLoS One 9, e112150 (2014).
    • (2014) PLoS One , vol.9 , pp. e112150
    • Wang, J.1
  • 47
    • 79651473733 scopus 로고    scopus 로고
    • FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-tomesenchymal transition in human lung cancers
    • Tang, Y., Shu, G., Yuan, X., Jing, N., Song, J. FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-tomesenchymal transition in human lung cancers. Cell Res. 21, 316-326 (2011).
    • (2011) Cell Res. , vol.21 , pp. 316-326
    • Tang, Y.1    Shu, G.2    Yuan, X.3    Jing, N.4    Song, J.5
  • 48
    • 80155137594 scopus 로고    scopus 로고
    • Master transcription factors determine cell-type-specific responses to TGF-signaling
    • Mullen, A. C. et al. Master transcription factors determine cell-type-specific responses to TGF-signaling. Cell 147, 565-576 (2011).
    • (2011) Cell , vol.147 , pp. 565-576
    • Mullen, A.C.1
  • 50
    • 80051874823 scopus 로고    scopus 로고
    • Mutational inactivation of STAG2 causes aneuploidy in human cancer
    • Solomon, D. a. et al. Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science 333, 1039-1043 (2011).
    • (2011) Science , vol.333 , pp. 1039-1043
    • Solomon, D.A.1
  • 51
    • 79952030327 scopus 로고    scopus 로고
    • Can corruption of chromosome cohesion create a conduit to cancer
    • Xu, H., Tomaszewski, J. M., McKay, M. J. Can corruption of chromosome cohesion create a conduit to cancerNat. Rev. Cancer 11, 199-210 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 199-210
    • Xu, H.1    Tomaszewski, J.M.2    McKay, M.J.3
  • 52
    • 80054097980 scopus 로고    scopus 로고
    • MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas
    • Mäkinen, N. et al. MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas. Science 334, 252-255 (2011).
    • (2011) Science , vol.334 , pp. 252-255
    • Mäkinen, N.1
  • 53
    • 84861581164 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
    • Barbieri, C. E. et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat. Genet. 44, 685-689 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 685-689
    • Barbieri, C.E.1
  • 54
    • 84949091882 scopus 로고    scopus 로고
    • Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo
    • Maurano, M. T. et al. Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo. Nat. Genet. 47, 1393-1401 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 1393-1401
    • Maurano, M.T.1
  • 55
    • 70350686180 scopus 로고    scopus 로고
    • SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
    • Bilodeau, S., Kagey, M. H., Frampton, G. M., Rahl, P. B., Young, R. A. SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev. 23, 2484-2489 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 2484-2489
    • Bilodeau, S.1    Kagey, M.H.2    Frampton, G.M.3    Rahl, P.B.4    Young, R.A.5
  • 56
    • 68549104404 scopus 로고    scopus 로고
    • The sequence alignment/map format and SAMtools
    • Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1
  • 57
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: A flexible suite of utilities for comparing genomic features
    • Quinlan, A. R., Hall, I. M. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841-842 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 58
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia, G., Singer, O., Verma, I. M. Production and purification of lentiviral vectors. Nat. Protoc. 1, 241-245 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 59
    • 0037417130 scopus 로고    scopus 로고
    • Functional analysis of the N-terminal domain of the Myc oncoprotein
    • Oster, S. K., Mao, D. Y. L., Kennedy, J., Penn, L. Z. Functional analysis of the N-terminal domain of the Myc oncoprotein. Oncogene 22, 1998-2010 (2003).
    • (2003) Oncogene , vol.22 , pp. 1998-2010
    • Oster, S.K.1    Mao, D.Y.L.2    Kennedy, J.3    Penn, L.Z.4
  • 60
    • 57749083496 scopus 로고    scopus 로고
    • Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements
    • Pan, Y. F. et al. Regulation of Estrogen Receptor-mediated Long Range Transcription via Evolutionarily Conserved Distal Response Elements. J. Biol. Chem. 283, 32977-32988 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 32977-32988
    • Pan, Y.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.