Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 42, 2016, Pages 11871-11876

  Wang, Chaochen ^a   Lee, Ji Eun ^a   Lai, Binbin ^a   Macfarlan, Todd S ^b   Xu, Shiliyang ^a   Zhuang, Lenan ^a   Liu, Chengyu ^c   Peng, Weiqun ^d   Ge, Kai ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Cell fate transition; Enhancer; H3K4 methyltransferase; MLL4 KMT2D; p300

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE H3; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; MLL4 PROTEIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; HISTONE; MLL3 PROTEIN, MOUSE; MLL4 PROTEIN, MOUSE; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL SELF-RENEWAL; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENHANCER REGION; ENZYME ACTIVITY; ENZYME BINDING; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM; SOMATIC CELL; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CYTOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENE KNOCKOUT; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PROMOTER REGION;

ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; CELL LINE; CELL SELF RENEWAL; CELLULAR REPROGRAMMING; E1A-ASSOCIATED P300 PROTEIN; EMBRYONIC STEM CELLS; ENHANCER ELEMENTS, GENETIC; FIBROBLASTS; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; INDUCED PLURIPOTENT STEM CELLS; MICE; MODELS, BIOLOGICAL; PROMOTER REGIONS, GENETIC; PROTEIN BINDING;

EID: 84991585545     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1606857113     Document Type: Article

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