Restoration of mitochondrial cardiolipin attenuates cardiac damage in swine renovascular hypertension

Journal of the American Heart Association

Volumn 5, Issue 6, 2016, Pages

  Eirin, Alfonso ^a   Ebrahimi, Behzad ^a   Kwon, Soon Hyo ^a   Fiala, Justin A ^a   Williams, Barbara J ^a   Woollard, John R ^a   He, Quan ^b   Gupta, Ramech C ^c   Sabbah, Hani N ^c   Prakash, Y S ^a   Textor, Stephen C ^a   Lerman, Amir ^a   Lerman, Lilach O ^a  

^a MAYO CLINIC   (United States)

^b BURNHAM INSTITUTE   (United States)

^c HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Bendavia; Heart failure; Hypertension; Mitochondria; Renal artery stenosis; Renovascular hypertension

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BRADYKININ; CARDIOLIPIN; ELAMIPRETIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2; VASCULOTROPIN; ANTIOXIDANT; ARGINYL-2,'6'-DIMETHYLTYROSYL-LYSYL-PHENYLALANINAMIDE; ENZYME INHIBITOR; OLIGOPEPTIDE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TERT BUTYL HYDROPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOENERGY; BLOOD PRESSURE; BOLD SIGNAL; CALCIUM CYCLING; CARDIAC MYOBLAST; CELL FUNCTION; CELL PROTECTION; CONTROLLED STUDY; CORONARY ENDOTHELIAL FUNCTION; DOMESTIC PIG; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; GENE EXPRESSION; HEART EJECTION FRACTION; HEART FUNCTION; HEART INJURY; HEART LEFT VENTRICLE RELAXATION; HEART MUSCLE INJURY; HEART PROTECTION; HEART RATE; HEART STROKE VOLUME; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HYPERCHOLESTEROLEMIA; IN VIVO STUDY; MITOCHONDRIAL BIOGENESIS; MITOCHONDRION; MITOPROTECTION; MULTIDETECTOR COMPUTED TOMOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; OXYGENATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENOVASCULAR HYPERTENSION; SARCOPLASMIC RETICULUM; VASCULAR REMODELING; ANIMAL; CARDIOMYOPATHY; COMPLICATION; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HEART LEFT VENTRICLE FUNCTION; HEART MITOCHONDRION; KIDNEY ARTERY STENOSIS; MAGNETIC RESONANCE ANGIOGRAPHY; METABOLISM; MICROVASCULATURE; PATHOPHYSIOLOGY; PHYSIOLOGY; PIG; PREVENTION AND CONTROL; RANDOMIZATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARDIOLIPINS; CARDIOMYOPATHIES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMALE; HYPERTENSION, RENOVASCULAR; MAGNETIC RESONANCE ANGIOGRAPHY; MICROVESSELS; MITOCHONDRIA, HEART; MITOCHONDRIAL DISEASES; MULTIDETECTOR COMPUTED TOMOGRAPHY; OLIGOPEPTIDES; RANDOM ALLOCATION; RENAL ARTERY OBSTRUCTION; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SUS SCROFA; SWINE; TERT-BUTYLHYDROPEROXIDE; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84991523754     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.003118     Document Type: Article

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