Early experimental hypertension preserves the myocardial microvasculature but aggravates cardiac injury distal to chronic coronary artery obstruction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 2, 2011, Pages

  Urbieta Caceres, Victor Hugo ^a   Lin, Jing ^a   Zhu, Xiang Yang ^a   Favreau, Frederic D ^a,b   Gibson, Matthew E ^a   Crane, John A ^a   Lerman, Amir ^a   Lerman, Lilach O ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITÉ DE POITIERS   (France)

Author keywords

Coronary artery stenosis; Microvascular dysfunction; Remodeling

Indexed keywords

ADENOSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY ARTERY OBSTRUCTION; DIASTOLE; FEMALE; HEART INJURY; HEART MUSCLE BLOOD FLOW; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HEART MUSCLE PERFUSION; HEART VENTRICLE REMODELING; HYPERTENSION; MICROVASCULATURE; MULTIDETECTOR COMPUTED TOMOGRAPHY; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; RENAL ARTERY; SWINE; SYSTOLE;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; BLOTTING, WESTERN; CAPILLARIES; CAPILLARY PERMEABILITY; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; CORONARY STENOSIS; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; FEMALE; FIBROSIS; HYPERTENSION, RENOVASCULAR; IMMUNOHISTOCHEMISTRY; MYOCARDITIS; MYOCARDIUM; STROKE VOLUME; SWINE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 79551470798     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00516.2010     Document Type: Article

References (43)

1. Antonios TF. Microvascular rarefaction in hypertension - reversal or over-correction by treatment? Am J Hypertens 19: 484-485, 2006.
2. Birukova AA, Adyshev D, Gorshkov B, Bokoch GM, Birukov KG, Verin AD. GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 290: L540-L548, 2006.
3. Brush JE Jr, Cannon RO 3rd, Schenke WH, Bonow RO, Leon MB, Maron BJ, Epstein SE. Angina due to coronary microvascular disease in hypertensive patients without left ventricular hypertrophy. N Engl J Med 319: 1302-1307, 1988.
4. Camici PG, Crea F. Coronary microvascular dysfunction. N Engl J Med 356: 830-840, 2007.
5. Chade AR, Herrmann J, Zhu X, Krier JD, Lerman A, Lerman LO. Effects of proteasome inhibition on the kidney in experimental hypercholesterolemia. J Am Soc Nephrol 16: 1005-1012, 2005.
6. Chade AR, Rodriguez-Porcel M, Herrmann J, Zhu X, Grande JP, Napoli C, Lerman A, Lerman LO. Antioxidant intervention blunts renal injury in experimental renovascular disease. J Am Soc Nephrol 15: 958-966, 2004. (Pubitemid 38375315)
7. Chade AR, Zhu X, Lavi R, Krier JD, Pislaru S, Simari RD, Napoli C, Lerman A, Lerman LO. Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation 119: 547-557, 2009.
8. 3 PET techniques. J Nucl Med 47: 1193-1201, 2006.
9. Collins NT, Cummins PM, Colgan OC, Ferguson G, Birney YA, Murphy RP, Meade G, Cahill PA. Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on intercellular tight junction assembly and function. Arterioscler Thromb Vasc Biol 26: 62-68, 2006. (Pubitemid 43732229)
10. Daghini E, Primak AN, Chade AR, Zhu X, Ritman EL, McCollough CH, Lerman LO. Evaluation of porcine myocardial microvascular permeability and fractional vascular volume using 64-slice helical computed tomography (CT). Invest Radiol 42: 274-282, 2007.
11. Favreau F, Zhu XY, Krier JD, Lin J, Warner L, Textor SC, Lerman LO. Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure. Kidney Int 78: 1110-1118, 2010.
12. Fukuda S, Kaga S, Sasaki H, Zhan L, Zhu L, Otani H, Kalfin R, Das DK, Maulik N. Angiogenic signal triggered by ischemic stress induces myocardial repair in rat during chronic infarction. J Mol Cell Cardiol 36: 547-559, 2004.
13. Gonzalez-Avila G, Iturria C, Vadillo-Ortega F, Ovalle C, Montano M. Changes in matrix metalloproteinases during the evolution of interstitial renal fibrosis in a rat experimental model. Pathobiology 66: 196-204, 1998.
14. Gould KL, Lipscomb K. Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol 34: 48-55, 1974.
15. Hamasaki S, Al Suwaidi J, Higano ST, Miyauchi K, Holmes DR Jr, Lerman A. Attenuated coronary flow reserve and vascular remodeling in patients with hypertension and left ventricular hypertrophy. J Am Coll Cardiol 35: 1654-1660, 2000. (Pubitemid 30307513)
16. Hashizume H, Baluk P, Morikawa S, McLean JW, Thurston G, Roberge S, Jain RK, McDonald DM. Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol 156: 1363-1380, 2000. (Pubitemid 30660013)
17. Herrmann J, Saguner AM, Versari D, Peterson TE, Chade A, Olson M, Lerman LO, Lerman A. Chronic proteasome inhibition contributes to coronary atherosclerosis. Circ Res 101: 865-874, 2007.
18. Lin J, Zhu X, Chade AR, Jordan KL, Lavi R, Daghini E, Gibson ME, Guglielmotti A, Lerman A, Lerman LO. Monocyte chemoattractant proteins mediate myocardial microvascular dysfunction in swine renovascular hypertension. Arterioscler Thromb Vasc Biol 29: 1810-1816, 2009.
19. Lobov IB, Renard RA, Papadopoulos N, Gale NW, Thurston G, Yancopoulos GD, Wiegand SJ. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad Sci USA 104: 3219-3224, 2007.
20. Marchesi C, Ebrahimian T, Angulo O, Paradis P, Schiffrin EL. Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome. Hypertension 54: 1384-1392, 2009.
21. Maric C, Sandberg K, Hinojosa-Laborde C. Glomerulosclerosis and tubulointerstitial fibrosis are attenuated with 17beta-estradiol in the aging Dahl salt sensitive rat. J Am Soc Nephrol 15: 1546-1556, 2004.
22. Mattern J, Koomagi R, Volm M. Coexpression of VEGF and bFGF in human epidermoid lung carcinoma is associated with increased vessel density. Anticancer Res 17: 2249-2252, 1997. (Pubitemid 27320977)
23. Mohlenkamp S, Lerman LO, Lerman A, Behrenbeck TR, Katusic ZS, Sheedy PF 2nd, Ritman EL. Minimally invasive evaluation of coronary microvascular function by electron beam computed tomography. Circulation 102: 2411-2416, 2000.
24. Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 323: 22-27, 1990. (Pubitemid 20209468)
25. Reddy HK, Campbell SE, Janicki JS, Zhou G, Weber KT. Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension. J Lab Clin Med 121: 510-521, 1993. (Pubitemid 23105716)
26. Rodriguez-Porcel M, Herrman J, Chade AR, Krier JD, Breen JF, Lerman A, Lerman LO. Long-term antioxidant intervention improves myocardial microvascular function in experimental hypertension. Hypertension 43: 493-498, 2004. (Pubitemid 38174160)
27. Rodriguez-Porcel M, Lerman A, Best PJ, Krier JD, Napoli C, Lerman LO. Hypercholesterolemia impairs myocardial perfusion and permeability: role of oxidative stress and endogenous scavenging activity. J Am Coll Cardiol 37: 608-615, 2001. (Pubitemid 32147278)
28. Rodriguez-Porcel M, Lerman A, Herrmann J, Schwartz RS, Sawamura T, Condorelli M, Napoli C, Lerman LO. Hypertension exacerbates the effect of hypercholesterolemia on the myocardial microvasculature. Cardiovasc Res 58: 213-221, 2003.
29. Rodriguez-Porcel M, Zhu XY, Chade AR, Amores-Arriaga B, Caplice NM, Ritman EL, Lerman A, Lerman LO. Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension. Am J Physiol Heart Circ Physiol 290: H978-H984, 2006.
30. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117: e25-e146, 2008.
31. Sasso FC, Torella D, Carbonara O, Ellison GM, Torella M, Scardone M, Marra C, Nasti R, Marfella R, Cozzolino D, Indolfi C, Cotrufo M, Torella R, Salvatore T. Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease. J Am Coll Cardiol 46: 827-834, 2005.
32. Sluimer JC, Kolodgie FD, Bijnens AP, Maxfield K, Pacheco E, Kutys B, Duimel H, Frederik PM, van Hinsbergh VW, Virmani R, Daemen MJ. Thin-walled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions. Relevance of compromised structural integrity for intraplaque microvascular leakage. J Am Coll Cardiol 53: 1517-1527, 2009.
33. Song L, Pachter JS. Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells. Microvasc Res 67: 78-89, 2004.
34. Suchting S, Freitas C, le Noble F, Benedito R, Breant C, Duarte A, Eichmann A. The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc Natl Acad Sci USA 104: 3225-3230, 2007. (Pubitemid 46364141)
35. Suuronen EJ, Veinot JP, Wong S, Kapila V, Price J, Griffith M, Mesana TG, Ruel M. Tissue-engineered injectable collagen-based matrices for improved cell delivery and vascularization of ischemic tissue using CD133+ progenitors expanded from the peripheral blood. Circulation 114: I138-I144, 2006.
36. Urbieta Caceres VH, Lavi R, Zhu XY, Crane JA, Textor SC, Lerman A, Lerman LO. Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney. Am J Physiol Renal Physiol 299: F135-F140, 2010.
37. Vu TH, Shipley JM, Bergers G, Berger JE, Helms JA, Hanahan D, Shapiro SD, Senior RM, Werb Z. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93: 411-422, 1998.
38. Willott E, Balda MS, Heintzelman M, Jameson B, Anderson JM. Localization and differential expression of two isoforms of the tight junction protein ZO-1. Am J Physiol Cell Physiol 262: C1119-C1124, 1992.
39. Zacharieva S, Atanassova I, Orbetzova M, Kirilov G, Nachev E, Kalinov K, Shigarminova R. Vascular endothelial growth factor (VEGF), prostaglandin E2 (PGE2) and active renin in hypertension of adrenal origin. J Endocrinol Invest 27: 742-746, 2004. (Pubitemid 39619061)
40. Zhu XY, Daghini E, Chade AR, Napoli C, Ritman EL, Lerman A, Lerman LO. Simvastatin prevents coronary microvascular remodeling in renovascular hypertensive pigs. J Am Soc Nephrol 18: 1209-1217, 2007. (Pubitemid 46536907)
41. Zhu XY, Daghini E, Chade AR, Rodriguez-Porcel M, Napoli C, Lerman A, Lerman LO. Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension. Arterioscler Thromb Vasc Biol 26: 1746-1752, 2006. (Pubitemid 44305327)
42. Zhu XY, Daghini E, Chade AR, Versari D, Krier JD, Textor KB, Lerman A, Lerman LO. Myocardial microvascular function during acute coronary artery stenosis: effect of hypertension and hypercholesterolaemia. Cardiovasc Res 83: 371-380, 2009.
43. Zhu XY, Rodriguez-Porcel M, Bentley MD, Chade AR, Sica V, Napoli C, Caplice N, Ritman EL, Lerman A, Lerman LO. Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia. Circulation 109: 2109-2115, 2004. (Pubitemid 38620220)