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Volumn 134, Issue 21, 2016, Pages e468-e495

Recommendations for Management of Clinically Significant Drug-Drug Interactions with Statins and Select Agents Used in Patients with Cardiovascular Disease: A Scientific Statement from the American Heart Association

Author keywords

AHA Scientific Statements; anti arrhythmic agents; anticoagulants; calcium channel blockers; cardiovascular disease; drug related side effects and adverse reactions; fenofibrate fenofibric acid derivatives; gemfibrozil; hydroxymethylglutaryl CoA reductase inhibitors; immunosuppressive agents

Indexed keywords

AMIODARONE; AMLODIPINE; ANTIARRHYTHMIC AGENT; ANTILIPEMIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; COLCHICINE; CONIVAPTAN; CYCLOSPORIN; CYTOCHROME P450; DIGOXIN; DILTIAZEM; DRONEDARONE; FENOFIBRATE; FENOFIBRIC ACID; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; IVABRADINE; MULTIDRUG RESISTANCE PROTEIN; NICOTINIC ACID; RANOLAZINE; RAPAMYCIN; SACUBITRIL; TACROLIMUS; TICAGRELOR; VALSARTAN; VASOPRESSIN RECEPTOR ANTAGONIST; VERAPAMIL; WARFARIN;

EID: 84991502977     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIR.0000000000000456     Document Type: Article
Times cited : (239)

References (189)
  • 2
    • 19544394711 scopus 로고    scopus 로고
    • Potential determinants of drug-drug interaction associated dispensing in community pharmacies
    • Becker ML, Kallewaard M, Caspers PW, Schalekamp T, Stricker BH. Potential determinants of drug-drug interaction associated dispensing in community pharmacies. Drug Saf. 2005;28:371-378.
    • (2005) Drug Saf. , vol.28 , pp. 371-378
    • Becker, M.L.1    Kallewaard, M.2    Caspers, P.W.3    Schalekamp, T.4    Stricker, B.H.5
  • 3
    • 0033576292 scopus 로고    scopus 로고
    • Drug-drug interactions: How scared should we be
    • Shapiro LE, Shear NH. Drug-drug interactions: how scared should we be? CMAJ. 1999;161:1266-1267.
    • (1999) CMAJ. , vol.161 , pp. 1266-1267
    • Shapiro, L.E.1    Shear, N.H.2
  • 4
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-1389.
    • (1994) Lancet. , vol.344 , pp. 1383-1389
  • 6
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels: The Long-Term Intervention and Pravastatin in Ischaemic Disease (LIPID) Study Group
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels: the Long-Term Intervention and Pravastatin in Ischaemic Disease (LIPID) Study Group. N Engl J Med. 1998;339:1349-1357. doi: 10.1056/NEJM199811053391902.
    • (1998) N Engl J Med. , vol.339 , pp. 1349-1357
  • 7
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomized placebo-controlled trial
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomized placebo-controlled trial. Lancet. 2002;360:7-22. doi: 10.1016/S0140-6736(02)09327-3.
    • (2002) Lancet. , vol.360 , pp. 7-22
    • Heart Protection Study Collaborative Group1
  • 8
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS: Air Force/Texas Coronary Atherosclerosis Prevention Study
    • Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR, Beere PA, Langendorfer A, Stein EA, Kruyer W, Gotto AM Jr. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS: Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA. 1998;279:1615-1622.
    • (1998) JAMA. , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3    Whitney, E.4    Shapiro, D.R.5    Beere, P.A.6    Langendorfer, A.7    Stein, E.A.8    Kruyer, W.9    Gotto, A.M.10
  • 9
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • Sever PS, Dahlöf B, Poulter NR, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J; ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet. 2003;361:1149-1158. doi: 10.1016/ S0140-6736(03)12948-0.
    • (2003) Lancet. , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlöf, B.2    Poulter, N.R.3    Wedel, H.4    Beevers, G.5    Caulfield, M.6    Collins, R.7    Kjeldsen, S.E.8    Kristinsson, A.9    McInnes, G.T.10    Mehlsen, J.11    Nieminen, M.12    O'Brien, E.13    Ostergren, J.14
  • 11
    • 0037068964 scopus 로고    scopus 로고
    • Clinical importance of the cytochromes P450
    • Nebert DW, Russell DW. Clinical importance of the cytochromes P450. Lancet. 2002;360:1155-1162. doi: 10.1016/S0140-6736(02)11203-7.
    • (2002) Lancet. , vol.360 , pp. 1155-1162
    • Nebert, D.W.1    Russell, D.W.2
  • 12
    • 19444376971 scopus 로고    scopus 로고
    • Drug metabolism and variability among patients in drug response
    • Wilkinson GR. Drug metabolism and variability among patients in drug response. N Engl J Med. 2005;352:2211-2221. doi: 10.1056/NEJMra032424.
    • (2005) N Engl J Med. , vol.352 , pp. 2211-2221
    • Wilkinson, G.R.1
  • 14
    • 0344837894 scopus 로고    scopus 로고
    • Investigation of the mutual pharmacokinetic interactions between bosentan, a dual endothelin receptor antagonist, and simvastatin
    • Dingemanse J, Schaarschmidt D, van Giersbergen PL. Investigation of the mutual pharmacokinetic interactions between bosentan, a dual endothelin receptor antagonist, and simvastatin. Clin Pharmacokinet. 2003;42:293-301. doi: 10.2165/00003088-200342030-00004.
    • (2003) Clin Pharmacokinet. , vol.42 , pp. 293-301
    • Dingemanse, J.1    Schaarschmidt, D.2    Van Giersbergen, P.L.3
  • 15
    • 0035076611 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and P-glycoprotein modulation
    • Bogman K, Peyer AK, Török M, Küsters E, Drewe J. HMG-CoA reductase inhibitors and P-glycoprotein modulation. Br J Pharmacol. 2001;132:1183-1192. doi: 10.1038/sj.bjp.0703920.
    • (2001) Br J Pharmacol. , vol.132 , pp. 1183-1192
    • Bogman, K.1    Peyer, A.K.2    Török, M.3    Küsters, E.4    Drewe, J.5
  • 16
    • 0036291921 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors
    • Williams D, Feely J. Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. Clin Pharmacokinet. 2002;41:343-370. doi: 10.2165/00003088-200241050-00003.
    • (2002) Clin Pharmacokinet. , vol.41 , pp. 343-370
    • Williams, D.1    Feely, J.2
  • 18
    • 0034866642 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein
    • Wang E, Casciano CN, Clement RP, Johnson WW. HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein. Pharm Res. 2001;18:800-806.
    • (2001) Pharm Res. , vol.18 , pp. 800-806
    • Wang, E.1    Casciano, C.N.2    Clement, R.P.3    Johnson, W.W.4
  • 19
    • 27544515516 scopus 로고    scopus 로고
    • Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMGCoA reductase
    • Fujino H, Saito T, Ogawa S, Kojima J. Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMGCoA reductase. J Pharm Pharmacol. 2005;57:1305-1311. doi: 10.1211/jpp.57.10.0009.
    • (2005) J Pharm Pharmacol. , vol.57 , pp. 1305-1311
    • Fujino, H.1    Saito, T.2    Ogawa, S.3    Kojima, J.4
  • 20
    • 84879232919 scopus 로고    scopus 로고
    • The P-glycoprotein transport system and cardiovascular drugs [published correction appears in J Am Coll Cardiol. 2014;63:2176].
    • Wessler JD, Grip LT, Mendell J, Giugliano RP. The P-glycoprotein transport system and cardiovascular drugs [published correction appears in J Am Coll Cardiol. 2014;63:2176]. J Am Coll Cardiol. 2013;61:2495-2502. doi: 10.1016/j.jacc.2013. 02.058.
    • (2013) J Am Coll Cardiol. , vol.61 , pp. 2495-2502
    • Wessler, J.D.1    Grip, L.T.2    Mendell, J.3    Giugliano, R.P.4
  • 22
    • 70350048926 scopus 로고    scopus 로고
    • Impact of OATP transporters on pharmacokinetics
    • Kalliokoski A, Niemi M. Impact of OATP transporters on pharmacokinetics. Br J Pharmacol. 2009;158:693-705. doi: 10.1111/j.1476-5381.2009.00430.x.
    • (2009) Br J Pharmacol. , vol.158 , pp. 693-705
    • Kalliokoski, A.1    Niemi, M.2
  • 23
    • 84866018277 scopus 로고    scopus 로고
    • The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins
    • Hua WJ, Hua WX, Fang HJ. The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins. Cardiovasc Ther. 2012;30:e234-e241. doi: 10.1111/j.1755-5922.2011.00290.x.
    • (2012) Cardiovasc Ther. , vol.30 , pp. e234-e241
    • Hua, W.J.1    Hua, W.X.2    Fang, H.J.3
  • 28
  • 31
    • 0035434397 scopus 로고    scopus 로고
    • Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins)
    • Igel M, Sudhop T, von Bergmann K. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). Eur J Clin Pharmacol. 2001;57:357-364.
    • (2001) Eur J Clin Pharmacol. , vol.57 , pp. 357-364
    • Igel, M.1    Sudhop, T.2    Von Bergmann, K.3
  • 32
    • 0141988934 scopus 로고    scopus 로고
    • Pitavastatin: Efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor
    • Kajinami K, Takekoshi N, Saito Y. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003;21:199-215.
    • (2003) Cardiovasc Drug Rev. , vol.21 , pp. 199-215
    • Kajinami, K.1    Takekoshi, N.2    Saito, Y.3
  • 33
    • 40049084668 scopus 로고    scopus 로고
    • Prioritization of clinical drug interaction studies using in vitro cytochrome P450 data: Proposed refinement and expansion of the "rank order" approach
    • Rodriques AD. Prioritization of clinical drug interaction studies using in vitro cytochrome P450 data: proposed refinement and expansion of the "rank order" approach. Drug Metab Lett.2007;1:31-35.
    • (2007) Drug Metab Lett , vol.1 , pp. 31-35
    • Rodriques, A.D.1
  • 34
    • 79955460186 scopus 로고    scopus 로고
    • Safety review of combination drugs for hyperlipidemia
    • Farnier M. Safety review of combination drugs for hyperlipidemia. Expert Opin Drug Saf. 2011;10:363-371. doi: 10.1517/14740338.2011.540237.
    • (2011) Expert Opin Drug Saf. , vol.10 , pp. 363-371
    • Farnier, M.1
  • 35
    • 4644301418 scopus 로고    scopus 로고
    • Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: Analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil
    • Shitara Y, Hirano M, Sato H, Sugiyama Y. Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil. J Pharmacol Exp Ther. 2004;311:228-236. doi: 10.1124/jpet.104.068536.
    • (2004) J Pharmacol Exp Ther. , vol.311 , pp. 228-236
    • Shitara, Y.1    Hirano, M.2    Sato, H.3    Sugiyama, Y.4
  • 36
    • 0038381566 scopus 로고    scopus 로고
    • Antilipemic therapy and rhabdomyolysis [in Hungarian]
    • Paragh G, Balogh Z, Romics L. Antilipemic therapy and rhabdomyolysis [in Hungarian]. Orv Hetil. 2003;144:515-520.
    • (2003) Orv Hetil. , vol.144 , pp. 515-520
    • Paragh, G.1    Balogh, Z.2    Romics, L.3
  • 38
    • 3042623891 scopus 로고    scopus 로고
    • Rhabdomyolysis with HMGCoA reductase inhibitors and gemfibrozil combination therapy
    • Chang JT, Staffa JA, Parks M, Green L. Rhabdomyolysis with HMGCoA reductase inhibitors and gemfibrozil combination therapy. Pharmacoepidemiol Drug Saf. 2004;13:417-426. doi: 10.1002/ pds.977.
    • (2004) Pharmacoepidemiol Drug Saf. , vol.13 , pp. 417-426
    • Chang, J.T.1    Staffa, J.A.2    Parks, M.3    Green, L.4
  • 39
    • 1542333320 scopus 로고    scopus 로고
    • Rhabdomyolysis and renal failure associated with gemfibrozil monotherapy
    • Layne RD, Sehbai AS, Stark LJ. Rhabdomyolysis and renal failure associated with gemfibrozil monotherapy. Ann Pharmacother. 2004;38:232-234. doi: 10.1345/aph.1D282.
    • (2004) Ann Pharmacother. , vol.38 , pp. 232-234
    • Layne, R.D.1    Sehbai, A.S.2    Stark, L.J.3
  • 40
    • 0034887738 scopus 로고    scopus 로고
    • Lipid-lowering drugs and risk of myopathy: A population-based follow-up study
    • Gaist D, Rodríguez LA, Huerta C, Hallas J, Sindrup SH. Lipid-lowering drugs and risk of myopathy: a population-based follow-up study. Epidemiology. 2001;12:565-569.
    • (2001) Epidemiology. , vol.12 , pp. 565-569
    • Gaist, D.1    Rodríguez, L.A.2    Huerta, C.3    Hallas, J.4    Sindrup, S.H.5
  • 41
    • 11144239674 scopus 로고    scopus 로고
    • Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin
    • Jones PH, Davidson MH. Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin. Am J Cardiol. 2005;95:120-122. doi: 10.1016/j.amjcard.2004.08.076.
    • (2005) Am J Cardiol. , vol.95 , pp. 120-122
    • Jones, P.H.1    Davidson, M.H.2
  • 42
    • 80053978944 scopus 로고    scopus 로고
    • Incidence of hospitalized rhabdomyolysis with statin and fibrate use in an insured US population
    • Amend KL, Landon J, Thyagarajan V, Niemcryk S, McAfee A. Incidence of hospitalized rhabdomyolysis with statin and fibrate use in an insured US population. Ann Pharmacother. 2011;45:1230-1239. doi: 10.1345/aph.1Q110.
    • (2011) Ann Pharmacother. , vol.45 , pp. 1230-1239
    • Amend, K.L.1    Landon, J.2    Thyagarajan, V.3    Niemcryk, S.4    McAfee, A.5
  • 43
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol: Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, Faas FH, Linares E, Schaefer EJ, Schectman G, Wilt TJ, Wittes J. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol: Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med. 1999;341:410-418. doi: 10.1056/NEJM199908053410604.
    • (1999) N Engl J Med. , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3    Fye, C.L.4    Anderson, J.W.5    Elam, M.B.6    Faas, F.H.7    Linares, E.8    Schaefer, E.J.9    Schectman, G.10    Wilt, T.J.11    Wittes, J.12
  • 45
    • 0025365041 scopus 로고
    • Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy
    • Pierce LR, Wysowski DK, Gross TP. Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy. JAMA. 1990;264:71-75.
    • (1990) JAMA. , vol.264 , pp. 71-75
    • Pierce, L.R.1    Wysowski, D.K.2    Gross, T.P.3
  • 47
    • 5344233372 scopus 로고    scopus 로고
    • Risk of adverse events with fibrates
    • Alsheikh-Ali AA, Kuvin JT, Karas RH. Risk of adverse events with fibrates. Am J Cardiol. 2004;94:935-938. doi: 10.1016/ j.amjcard.2004.06.033.
    • (2004) Am J Cardiol. , vol.94 , pp. 935-938
    • Alsheikh-Ali, A.A.1    Kuvin, J.T.2    Karas, R.H.3
  • 48
    • 33645868967 scopus 로고    scopus 로고
    • Statin safety and drug interactions: Clinical implications
    • Bottorff MB. Statin safety and drug interactions: clinical implications. Am J Cardiol. 2006;97:27C-31C. doi: 10.1016/ j.amjcard.2005.12.007.
    • (2006) Am J Cardiol. , vol.97 , pp. 27C-31C
    • Bottorff, M.B.1
  • 50
    • 29944446317 scopus 로고    scopus 로고
    • Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: Implications for drug-drug interactions
    • Ogilvie BW, Zhang D, Li W, Rodrigues AD, Gipson AE, Holsapple J, Toren P, Parkinson A. Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions. Drug Metab Dispos. 2006;34:191-197. doi: 10.1124/dmd.105.007633.
    • (2006) Drug Metab Dispos. , vol.34 , pp. 191-197
    • Ogilvie, B.W.1    Zhang, D.2    Li, W.3    Rodrigues, A.D.4    Gipson, A.E.5    Holsapple, J.6    Toren, P.7    Parkinson, A.8
  • 52
    • 84867873811 scopus 로고    scopus 로고
    • Understanding the critical disposition pathways of statins to assess drug-drug interaction risk during drug development: It's not just about OATP1B1
    • Elsby R, Hilgendorf C, Fenner K. Understanding the critical disposition pathways of statins to assess drug-drug interaction risk during drug development: it's not just about OATP1B1. Clin Pharmacol Ther. 2012;92:584-598. doi: 10.1038/clpt.2012.163.
    • (2012) Clin Pharmacol Ther. , vol.92 , pp. 584-598
    • Elsby, R.1    Hilgendorf, C.2    Fenner, K.3
  • 53
    • 34547154774 scopus 로고    scopus 로고
    • Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid
    • Goosen TC, Bauman JN, Davis JA, Yu C, Hurst SI, Williams JA, Loi CM. Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid. Drug Metab Dispos. 2007;35:1315-1324. doi: 10.1124/ dmd.107.015230.
    • (2007) Drug Metab Dispos. , vol.35 , pp. 1315-1324
    • Goosen, T.C.1    Bauman, J.N.2    Davis, J.A.3    Yu, C.4    Hurst, S.I.5    Williams, J.A.6    Loi, C.M.7
  • 56
    • 79953813165 scopus 로고    scopus 로고
    • Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin
    • Whitfield LR, Porcari AR, Alvey C, Abel R, Bullen W, Hartman D. Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin. J Clin Pharmacol. 2011;51:378-388. doi: 10.1177/0091270010366446.
    • (2011) J Clin Pharmacol. , vol.51 , pp. 378-388
    • Whitfield, L.R.1    Porcari, A.R.2    Alvey, C.3    Abel, R.4    Bullen, W.5    Hartman, D.6
  • 57
    • 23444452547 scopus 로고    scopus 로고
    • Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites
    • Backman JT, Luurila H, Neuvonen M, Neuvonen PJ. Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites. Clin Pharmacol Ther. 2005;78:154-167. doi: 10.1016/j.clpt.2005.04.007.
    • (2005) Clin Pharmacol Ther. , vol.78 , pp. 154-167
    • Backman, J.T.1    Luurila, H.2    Neuvonen, M.3    Neuvonen, P.J.4
  • 58
    • 0037534010 scopus 로고    scopus 로고
    • Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance
    • Kyrklund C, Backman JT, Neuvonen M, Neuvonen PJ. Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance. Clin Pharmacol Ther. 2003;73:538-544. doi: 10.1016/S0009-9236(03)00052-3.
    • (2003) Clin Pharmacol Ther. , vol.73 , pp. 538-544
    • Kyrklund, C.1    Backman, J.T.2    Neuvonen, M.3    Neuvonen, P.J.4
  • 60
    • 77954647557 scopus 로고    scopus 로고
    • Effect of a single gemfibrozil dose on the pharmacokinetics of rosuvastatin in bile and plasma in healthy volunteers
    • Bergman E, Matsson EM, Hedeland M, Bondesson U, Knutson L, Lennernäs H. Effect of a single gemfibrozil dose on the pharmacokinetics of rosuvastatin in bile and plasma in healthy volunteers. J Clin Pharmacol. 2010;50:1039-1049. doi: 10.1177/0091270009357432.
    • (2010) J Clin Pharmacol. , vol.50 , pp. 1039-1049
    • Bergman, E.1    Matsson, E.M.2    Hedeland, M.3    Bondesson, U.4    Knutson, L.5    Lennernäs, H.6
  • 61
    • 4644272415 scopus 로고    scopus 로고
    • An open-label study on the pharmacokinetics (PK) of pitavastatin (NK-104) when administered concomitantly with fenofibrate or gemfibrozil in healthy volunteers
    • Mathew P, Cuddy T, Tracewell WG, Salazar D. An open-label study on the pharmacokinetics (PK) of pitavastatin (NK-104) when administered concomitantly with fenofibrate or gemfibrozil in healthy volunteers. Clin Pharmacol Ther. 2004;75:33.
    • (2004) Clin Pharmacol Ther. , vol.75 , pp. 33
    • Mathew, P.1    Cuddy, T.2    Tracewell, W.G.3    Salazar, D.4
  • 62
    • 34547178337 scopus 로고    scopus 로고
    • Substrate-dependent drugdrug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3
    • Noé J, Portmann R, Brun ME, Funk C. Substrate-dependent drugdrug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. Drug Metab Dispos. 2007;35:1308-1314. doi: 10.1124/dmd.106.012930.
    • (2007) Drug Metab Dispos. , vol.35 , pp. 1308-1314
    • Noé, J.1    Portmann, R.2    Brun, M.E.3    Funk, C.4
  • 64
    • 84881135658 scopus 로고    scopus 로고
    • Adherence to drug label recommendations for avoiding drug interactions causing statin-induced myopathy: A nationwide register study
    • Settergren J, Eiermann B, Mannheimer B. Adherence to drug label recommendations for avoiding drug interactions causing statin-induced myopathy: a nationwide register study. PLoS One. 2013;8:e69545. doi: 10.1371/journal.pone.0069545.
    • (2013) PLoS One. , vol.8 , pp. e69545
    • Settergren, J.1    Eiermann, B.2    Mannheimer, B.3
  • 67
    • 4644220820 scopus 로고    scopus 로고
    • The renal patient with coronary artery disease: Current concepts and dilemmas [published correction appears in J Am Coll Cardiol.2004;44:2283]
    • Gupta R, Birnbaum Y, Uretsky BF. The renal patient with coronary artery disease: current concepts and dilemmas [published correction appears in J Am Coll Cardiol. 2004;44:2283]. J Am Coll Cardiol. 2004;44:1343-1353. doi: 10.1016/j. jacc.2004.06.058.
    • (2004) J Am Coll Cardiol. , vol.44 , pp. 1343-1353
    • Gupta, R.1    Birnbaum, Y.2    Uretsky, B.F.3
  • 69
    • 0034145932 scopus 로고    scopus 로고
    • Lack of a clinically significant pharmacokinetic interaction between fenofibrate and pravastatin in healthy volunteers
    • Pan WJ, Gustavson LE, Achari R, Rieser MJ, Ye X, Gutterman C, Wallin BA. Lack of a clinically significant pharmacokinetic interaction between fenofibrate and pravastatin in healthy volunteers. J Clin Pharmacol. 2000;40:316-323.
    • (2000) J Clin Pharmacol. , vol.40 , pp. 316-323
    • Pan, W.J.1    Gustavson, L.E.2    Achari, R.3    Rieser, M.J.4    Ye, X.5    Gutterman, C.6    Wallin, B.A.7
  • 70
    • 0037292311 scopus 로고    scopus 로고
    • An open-label, randomized, three-way crossover trial of the effects of coadministration of rosuvastatin and fenofibrate on the pharmacokinetic properties of rosuvastatin and fenofibric acid in healthy male volunteers
    • Martin PD, Dane AL, Schneck DW, Warwick MJ. An open-label, randomized, three-way crossover trial of the effects of coadministration of rosuvastatin and fenofibrate on the pharmacokinetic properties of rosuvastatin and fenofibric acid in healthy male volunteers. Clin Ther. 2003;25:459-471.
    • (2003) Clin Ther. , vol.25 , pp. 459-471
    • Martin, P.D.1    Dane, A.L.2    Schneck, D.W.3    Warwick, M.J.4
  • 71
    • 58149181570 scopus 로고    scopus 로고
    • ABT-335, the choline salt of fenofibric acid, does not have a clinically significant pharmacokinetic interaction with rosuvastatin in humans
    • Zhu T, Awni WM, Hosmane B, Kelly MT, Sleep DJ, Stolzenbach JC, Wan K, Chira TO, Pradhan RS. ABT-335, the choline salt of fenofibric acid, does not have a clinically significant pharmacokinetic interaction with rosuvastatin in humans. J Clin Pharmacol. 2009;49:63-71. doi: 10.1177/0091270008325671.
    • (2009) J Clin Pharmacol. , vol.49 , pp. 63-71
    • Zhu, T.1    Awni, W.M.2    Hosmane, B.3    Kelly, M.T.4    Sleep, D.J.5    Stolzenbach, J.C.6    Wan, K.7    Chira, T.O.8    Pradhan, R.S.9
  • 74
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy [published correction appears in N Engl J Med 2012;367:189]
    • AIM-HIGH Investigators, Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, McBride R, Teo K, Weintraub W. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy [published correction appears in N Engl J Med. 2012;367:189]. N Engl J Med. 2011;365:2255-2267. doi: 10.1056/NEJMoa1107579.
    • (2011) N Engl J Med. , vol.365 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3    Chaitman, B.R.4    Desvignes-Nickens, P.5    Koprowicz, K.6    McBride, R.7    Teo, K.8    Weintraub, W.9
  • 75
    • 84877299845 scopus 로고    scopus 로고
    • HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/ laropiprant: Trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
    • HPS2-THRIVE Collaborative Group. HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/ laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment. Eur Heart J. 2013;34:1279-1291. doi:10.1093/eurheartj/eht55.
    • (2013) Eur Heart J. , vol.34 , pp. 1279-1291
  • 76
    • 34249049430 scopus 로고    scopus 로고
    • Calcium channel antagonists: Clinical uses-past, present and future
    • Triggle DJ. Calcium channel antagonists: clinical uses-past, present and future. Biochem Pharmacol. 2007;74:1-9. doi: 10.1016/j.bcp.2007.01.016.
    • (2007) Biochem Pharmacol. , vol.74 , pp. 1-9
    • Triggle, D.J.1
  • 77
  • 78
    • 4644336965 scopus 로고    scopus 로고
    • New advances in the field of calcium channel antagonists: Cardiovascular effects and structure-activity relationships
    • Romero M, Sánchez I, Pujol MD. New advances in the field of calcium channel antagonists: cardiovascular effects and structure-activity relationships. Curr Med Chem Cardiovasc Hematol Agents. 2003;1:113-141.
    • (2003) Curr Med Chem Cardiovasc Hematol Agents. , vol.1 , pp. 113-141
    • Romero, M.1    Sánchez, I.2    Pujol, M.D.3
  • 79
    • 45549089673 scopus 로고    scopus 로고
    • Risk management of simvastatin or atorvastatin interactions with CYP3A4 inhibitors
    • Molden E, Skovlund E, Braathen P. Risk management of simvastatin or atorvastatin interactions with CYP3A4 inhibitors. Drug Saf. 2008;31:587-596.
    • (2008) Drug Saf. , vol.31 , pp. 587-596
    • Molden, E.1    Skovlund, E.2    Braathen, P.3
  • 80
    • 45549091043 scopus 로고    scopus 로고
    • Pharmacokinetic comparison of the potential over-The-counter statins simvastatin, lovastatin, fluvastatin and pravastatin
    • Neuvonen PJ, Backman JT, Niemi M. Pharmacokinetic comparison of the potential over-The-counter statins simvastatin, lovastatin, fluvastatin and pravastatin. Clin Pharmacokinet. 2008;47:463-474. doi: 10.2165/00003088-200847070-00003.
    • (2008) Clin Pharmacokinet. , vol.47 , pp. 463-474
    • Neuvonen, P.J.1    Backman, J.T.2    Niemi, M.3
  • 81
    • 57049137177 scopus 로고    scopus 로고
    • Multiple drug interactions in a renal transplant patient leading to simvastatin-induced rhabdomyolysis: A case report
    • Rifkin SI. Multiple drug interactions in a renal transplant patient leading to simvastatin-induced rhabdomyolysis: a case report. Medscape J Med. 2008;10:264.
    • (2008) Medscape J Med. , vol.10 , pp. 264
    • Rifkin, S.I.1
  • 82
    • 77958529099 scopus 로고    scopus 로고
    • Effects of concomitant therapy with diltiazem on the lipid responses to simvastatin in Chinese subjects
    • You JH, Chan WK, Chung PF, Hu M, Tomlinson B. Effects of concomitant therapy with diltiazem on the lipid responses to simvastatin in Chinese subjects. J Clin Pharmacol. 2010;50:1151-1158. doi: 10.1177/0091270009358082.
    • (2010) J Clin Pharmacol. , vol.50 , pp. 1151-1158
    • You, J.H.1    Chan, W.K.2    Chung, P.F.3    Hu, M.4    Tomlinson, B.5
  • 83
    • 79955750364 scopus 로고    scopus 로고
    • Simvastatin-induced myopathy, the role of interaction with diltiazem and genetic predisposition
    • Hu M, Mak VW, Tomlinson B. Simvastatin-induced myopathy, the role of interaction with diltiazem and genetic predisposition. J Clin Pharm Ther. 2011;36:419-425. doi: 10.1111/ j.1365-2710.2010.01184.x.
    • (2011) J Clin Pharm Ther. , vol.36 , pp. 419-425
    • Hu, M.1    Mak, V.W.2    Tomlinson, B.3
  • 86
    • 0036786092 scopus 로고    scopus 로고
    • Rhabdomyolysis with concurrent atorvastatin and diltiazem
    • Lewin JJ 3rd, Nappi JM, Taylor MH. Rhabdomyolysis with concurrent atorvastatin and diltiazem. Ann Pharmacother. 2002;36:1546-1549.
    • (2002) Ann Pharmacother. , vol.36 , pp. 1546-1549
    • Lewin, J.J.1    Nappi, J.M.2    Taylor, M.H.3
  • 87
    • 72149099860 scopus 로고    scopus 로고
    • Effects of simvastatin on the pharmacokinetics of verapamil and its main metabolite, norverapamil, in rats
    • Choi DH, Li C, Choi JS. Effects of simvastatin on the pharmacokinetics of verapamil and its main metabolite, norverapamil, in rats. Eur J Drug Metab Pharmacokinet. 2009;34:163-168.
    • (2009) Eur J Drug Metab Pharmacokinet. , vol.34 , pp. 163-168
    • Choi, D.H.1    Li, C.2    Choi, J.S.3
  • 88
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) [published corrections appear in JAMA. 2003;289:178 and JAMA. 2004;291:2196
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) [published corrections appear in JAMA. 2003;289:178 and JAMA. 2004;291:2196]. JAMA. 2002;288:2981-2997.
    • (2002) JAMA. , vol.288 , pp. 2981-2997
  • 89
  • 90
    • 84996469022 scopus 로고    scopus 로고
    • Macquarie Park, NSW: Sanofi-Aventis, Australia Pty Ltd
    • Diltiazem [package insert]. Macquarie Park, NSW: Sanofi-Aventis, Australia Pty Ltd; 2014.
    • (2014) Diltiazem [Package Insert]
  • 91
    • 84996446174 scopus 로고    scopus 로고
    • New York, NY: Pfizer Labs
    • Verapamil [package insert]. New York, NY: Pfizer Labs; 2011.
    • (2011) Verapamil [Package Insert]
  • 92
    • 19844378287 scopus 로고    scopus 로고
    • Adverse events with concomitant amiodarone and statin therapy
    • Alsheikh-Ali AA, Karas RH. Adverse events with concomitant amiodarone and statin therapy. Prev Cardiol. 2005;8:95-97.
    • (2005) Prev Cardiol. , vol.8 , pp. 95-97
    • Alsheikh-Ali, A.A.1    Karas, R.H.2
  • 96
    • 1542783160 scopus 로고    scopus 로고
    • Amiodarone's role in simvastatin-associated rhabdomyolysis
    • de Denus S, Spinler SA. Amiodarone's role in simvastatin-associated rhabdomyolysis. Am J Health Syst Pharm. 2003;60:1791; author reply 1791-1792.
    • (2003) Am J Health Syst Pharm. , vol.60 , pp. 1791-1792
    • De Denus, S.1    Spinler, S.A.2
  • 98
    • 33144462199 scopus 로고    scopus 로고
    • Myopathy from the combination of simvastatin and amiodarone
    • Saliba WR, Elias M. Myopathy from the combination of simvastatin and amiodarone. Eur J Intern Med. 2006;17:148. doi: 10.1016/j.ejim.2005.09.018.
    • (2006) Eur J Intern Med. , vol.17 , pp. 148
    • Saliba, W.R.1    Elias, M.2
  • 99
    • 33646241551 scopus 로고    scopus 로고
    • Simvastatinamiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity
    • Ricaurte B, Guirguis A, Taylor HC, Zabriskie D. Simvastatinamiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity. Ann Pharmacother. 2006;40:753-757. doi: 10.1345/aph.1G462.
    • (2006) Ann Pharmacother. , vol.40 , pp. 753-757
    • Ricaurte, B.1    Guirguis, A.2    Taylor, H.C.3    Zabriskie, D.4
  • 100
    • 79960961358 scopus 로고    scopus 로고
    • Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: A case report and review of the literature
    • Marot A, Morelle J, Chouinard VA, Jadoul M, Lambert M, Demoulin N. Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: a case report and review of the literature. Acta Clin Belg. 2011;66:134-136. doi: 10.2143/ ACB.66.2.20625533.
    • (2011) Acta Clin Belg. , vol.66 , pp. 134-136
    • Marot, A.1    Morelle, J.2    Chouinard, V.A.3    Jadoul, M.4    Lambert, M.5    Demoulin, N.6
  • 101
    • 34848923693 scopus 로고    scopus 로고
    • Elevated serum transaminase levels resulting from concomitant use of rosuvastatin and amiodarone
    • Merz T, Fuller SH. Elevated serum transaminase levels resulting from concomitant use of rosuvastatin and amiodarone. Am J Health Syst Pharm. 2007;64:1818-1821. doi: 10.2146/ajhp060305.
    • (2007) Am J Health Syst Pharm. , vol.64 , pp. 1818-1821
    • Merz, T.1    Fuller, S.H.2
  • 102
    • 25844499828 scopus 로고    scopus 로고
    • Simvastatin interaction with clarithromycin and amiodarone causing myositis
    • Chouhan UM, Chakrabarti S, Millward LJ. Simvastatin interaction with clarithromycin and amiodarone causing myositis. Ann Pharmacother. 2005;39:1760-1761. doi: 10.1345/aph.1G195.
    • (2005) Ann Pharmacother. , vol.39 , pp. 1760-1761
    • Chouhan, U.M.1    Chakrabarti, S.2    Millward, L.J.3
  • 104
    • 78449267756 scopus 로고    scopus 로고
    • Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: A double-blind randomised trial
    • Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group
    • Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group, Armitage J, Bowman L, Wallendszus K, Bulbulia R, Rahimi K, Haynes R, Parish S, Peto R, Collins R. Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial. Lancet. 2010;376:1658-1669. doi: 10.1016/ S0140-6736(10)60310-8.
    • (2010) Lancet. , vol.376 , pp. 1658-1669
    • Armitage, J.1    Bowman, L.2    Wallendszus, K.3    Bulbulia, R.4    Rahimi, K.5    Haynes, R.6    Parish, S.7    Peto, R.8    Collins, R.9
  • 105
    • 0025688313 scopus 로고
    • Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel Antiarrhythmic Study of Infarct Survival (BASIS)
    • Burkart F, Pfisterer M, Kiowski W, Follath F, Burckhardt D. Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel Antiarrhythmic Study of Infarct Survival (BASIS). J Am Coll Cardiol. 1990;16:1711-1718.
    • (1990) J Am Coll Cardiol. , vol.16 , pp. 1711-1718
    • Burkart, F.1    Pfisterer, M.2    Kiowski, W.3    Follath, F.4    Burckhardt, D.5
  • 106
    • 0031029373 scopus 로고    scopus 로고
    • Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT: Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators [published correction appears in Lancet 1997;349:1776
    • Cairns JA, Connolly SJ, Roberts R, Gent M. Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT: Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators [published correction appears in Lancet. 1997;349:1776]. Lancet. 1997;349:675-682.
    • (1997) Lancet. , vol.349 , pp. 675-682
    • Cairns, J.A.1    Connolly, S.J.2    Roberts, R.3    Gent, M.4
  • 107
    • 0027998462 scopus 로고
    • Randomised trial of low-dose amiodarone in severe congestive heart failure: Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA)
    • Doval HC, Nul DR, Grancelli HO, Perrone SV, Bortman GR, Curiel R. Randomised trial of low-dose amiodarone in severe congestive heart failure: Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA). Lancet. 1994;344:493-498.
    • (1994) Lancet. , vol.344 , pp. 493-498
    • Doval, H.C.1    Nul, D.R.2    Grancelli, H.O.3    Perrone, S.V.4    Bortman, G.R.5    Curiel, R.6
  • 108
    • 0031038213 scopus 로고    scopus 로고
    • Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT: European Myocardial Infarct Amiodarone Trial Investigators [published corrections appear in Lancet 1997;349:1180 and Lancet. 1997 349 1776
    • Julian DG, Camm AJ, Frangin G, Janse MJ, Munoz A, Schwartz PJ, Simon P. Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT: European Myocardial Infarct Amiodarone Trial Investigators [published corrections appear in Lancet. 1997;349:1180 and Lancet. 1997;349:1776]. Lancet. 1997;349:667-674.
    • (1997) Lancet. , vol.349 , pp. 667-674
    • Julian, D.G.1    Camm, A.J.2    Frangin, G.3    Janse, M.J.4    Munoz, A.5    Schwartz, P.J.6    Simon, P.7
  • 109
    • 9844224486 scopus 로고    scopus 로고
    • A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators
    • A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias: the Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators. N Engl J Med. 1997;337:1576-1583. doi: 10.1056/NEJM199711273372202.
    • (1997) N Engl J Med. , vol.337 , pp. 1576-1583
  • 110
    • 66749174587 scopus 로고    scopus 로고
    • Concurrent use of statins and amiodarone
    • Borders-Hemphill V. Concurrent use of statins and amiodarone. Consult Pharm. 2009;24:372-379.
    • (2009) Consult Pharm. , vol.24 , pp. 372-379
    • Borders-Hemphill, V.1
  • 111
    • 77958538072 scopus 로고    scopus 로고
    • Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center
    • Karimi S, Hough A, Beckey C, Parra D. Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center. J Manag Care Pharm. 2010;16:472-481. doi: 10.18553/jmcp.2010.16.7.472.
    • (2010) J Manag Care Pharm. , vol.16 , pp. 472-481
    • Karimi, S.1    Hough, A.2    Beckey, C.3    Parra, D.4
  • 112
    • 84899501175 scopus 로고    scopus 로고
    • Potential statin-drug interactions: Prevalence and clinical significance
    • Zhelyazkova-Savova M, Gancheva S, Sirakova V. Potential statin-drug interactions: prevalence and clinical significance. Springerplus. 2014;3:168. doi: 10.1186/2193-1801-3-168.
    • (2014) Springerplus. , vol.3 , pp. 168
    • Zhelyazkova-Savova, M.1    Gancheva, S.2    Sirakova, V.3
  • 113
    • 34247235590 scopus 로고    scopus 로고
    • Dronedarone: An amiodarone analog for the treatment of atrial fibrillation and atrial flutter
    • Dale KM, White CM. Dronedarone: an amiodarone analog for the treatment of atrial fibrillation and atrial flutter. Ann Pharmacother. 2007;41:599-605. doi: 10.1345/aph.1H524.
    • (2007) Ann Pharmacother. , vol.41 , pp. 599-605
    • Dale, K.M.1    White, C.M.2
  • 114
    • 60549097431 scopus 로고    scopus 로고
    • Effect of dronedarone on cardiovascular events in atrial fibrillation [published correction appears in N Engl J Med 2009;360:2487
    • Hohnloser SH, Crijns HJ, van Eickels M, Gaudin C, Page RL, Torp-Pedersen C, Connolly SJ; ATHENA Investigators. Effect of dronedarone on cardiovascular events in atrial fibrillation [published correction appears in N Engl J Med. 2009;360:2487]. N Engl J Med. 2009;360:668-678. doi: 10.1056/NEJMoa0803778.
    • (2009) N Engl J Med. , vol.360 , pp. 668-678
    • Hohnloser, S.H.1    Crijns, H.J.2    Van Eickels, M.3    Gaudin, C.4    Page, R.L.5    Torp-Pedersen, C.6    Connolly, S.J.7
  • 116
    • 77952604921 scopus 로고    scopus 로고
    • A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: The DIONYSOS study
    • Le Heuzey JY, De Ferrari GM, Radzik D, Santini M, Zhu J, Davy JM. A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study. J Cardiovasc Electrophysiol. 2010;21:597-605. doi: 10.1111/j.1540-8167.2010.01764.x.
    • (2010) J Cardiovasc Electrophysiol. , vol.21 , pp. 597-605
    • Le Heuzey, J.Y.1    De Ferrari, G.M.2    Radzik, D.3    Santini, M.4    Zhu, J.5    Davy, J.M.6
  • 117
    • 84996445949 scopus 로고    scopus 로고
    • NC: GlaxoSmithKline. Accessed August 28, 2016.
    • Digoxin [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2009. http://www.accessdata.fda.gov/drugsatfda- docs/label/2010/009330s025lbl.pdf. Accessed August 28, 2016.
    • (2009) Digoxin [Package Insert Research Triangle Park
  • 119
    • 33646140572 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of ranolazine
    • Jerling M. Clinical pharmacokinetics of ranolazine. Clin Pharmacokinet. 2006;45:469-491. doi: 10.2165/00003088-200645050-00003.
    • (2006) Clin Pharmacokinet. , vol.45 , pp. 469-491
    • Jerling, M.1
  • 120
    • 16844369128 scopus 로고    scopus 로고
    • Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects
    • Jerling M, Huan BL, Leung K, Chu N, Abdallah H, Hussein Z. Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects. J Clin Pharmacol. 2005;45:422-433. doi: 10.1177/0091270004273992.
    • (2005) J Clin Pharmacol. , vol.45 , pp. 422-433
    • Jerling, M.1    Huan, B.L.2    Leung, K.3    Chu, N.4    Abdallah, H.5    Hussein, Z.6
  • 121
    • 79952201860 scopus 로고    scopus 로고
    • Rhabdomyolysis in a patient receiving ranolazine and simvastatin
    • Hylton AC, Ezekiel TO. Rhabdomyolysis in a patient receiving ranolazine and simvastatin. Am J Health Syst Pharm. 2010;67:1829-1831. doi: 10.2146/ajhp090299.
    • (2010) Am J Health Syst Pharm. , vol.67 , pp. 1829-1831
    • Hylton, A.C.1    Ezekiel, T.O.2
  • 122
    • 84875434213 scopus 로고    scopus 로고
    • Ranolazine-induced myopathy in a patient on chronic statin therapy
    • Correa D, Landau M. Ranolazine-induced myopathy in a patient on chronic statin therapy. J Clin Neuromuscul Dis. 2013;14:114-116. doi: 10.1097/CND.0b013e31828525a5.
    • (2013) J Clin Neuromuscul Dis. , vol.14 , pp. 114-116
    • Correa, D.1    Landau, M.2
  • 123
  • 124
    • 34247526904 scopus 로고    scopus 로고
    • Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes: The MERLIN-TIMI 36 randomized trial
    • Morrow DA, Scirica BM, Karwatowska-Prokopczuk E, Murphy SA, Budaj A, Varshavsky S, Wolff AA, Skene A, McCabe CH, Braunwald E; MERLIN-TIMI 36 Trial Investigators. Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes: the MERLIN-TIMI 36 randomized trial. JAMA. 2007;297:1775-1783. doi: 10.1001/ jama.297.16.1775.
    • (2007) JAMA. , vol.297 , pp. 1775-1783
    • Morrow, D.A.1    Scirica, B.M.2    Karwatowska-Prokopczuk, E.3    Murphy, S.A.4    Budaj, A.5    Varshavsky, S.6    Wolff, A.A.7    Skene, A.8    McCabe, C.H.9    Braunwald, E.10
  • 125
    • 84877776301 scopus 로고    scopus 로고
    • Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: Results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects with Chronic Stable Angina)
    • Kosiborod M, Arnold SV, Spertus JA, McGuire DK, Li Y, Yue P, Ben-Yehuda O, Katz A, Jones PG, Olmsted A, Belardinelli L, Chaitman BR. Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina). J Am Coll Cardiol. 2013;61:2038-2045. doi: 10.1016/j.jacc.2013.02.011.
    • (2013) J Am Coll Cardiol. , vol.61 , pp. 2038-2045
    • Kosiborod, M.1    Arnold, S.V.2    Spertus, J.A.3    McGuire, D.K.4    Li, Y.5    Yue, P.6    Ben-Yehuda, O.7    Katz, A.8    Jones, P.G.9    Olmsted, A.10    Belardinelli, L.11    Chaitman, B.R.12
  • 127
    • 84996469623 scopus 로고    scopus 로고
    • Foster City, CA; Gilead Sciences, Inc. January
    • Ranolazine [package insert]. Foster City, CA; Gilead Sciences, Inc. January 2016.
    • (2016) Ranolazine [Package Insert]
  • 129
    • 84857862416 scopus 로고    scopus 로고
    • Acute rhabdomyolysis caused by combination therapy with atorvastatin and warfarin
    • Mackay JW, Fenech ME, Myint KS. Acute rhabdomyolysis caused by combination therapy with atorvastatin and warfarin. Br J Hosp Med (Lond). 2012;73:106-107.
    • (2012) Br J Hosp Med (Lond). , vol.73 , pp. 106-107
    • Mackay, J.W.1    Fenech, M.E.2    Myint, K.S.3
  • 130
    • 0038291753 scopus 로고    scopus 로고
    • The effect of simvastatin co-medication on warfarin anticoagulation response and dose requirements
    • Hickmott H, Wynne H, Kamali F. The effect of simvastatin co-medication on warfarin anticoagulation response and dose requirements. Thromb Haemost. 2003;89:949-950. doi: 10.1267/ THRO03050949.
    • (2003) Thromb Haemost. , vol.89 , pp. 949-950
    • Hickmott, H.1    Wynne, H.2    Kamali, F.3
  • 132
    • 0032895810 scopus 로고    scopus 로고
    • The effect of converting from pravastatin to simvastatin on the pharmacodynamics of warfarin
    • Lin JC, Ito MK, Stolley SN, Morreale AP, Marcus DB. The effect of converting from pravastatin to simvastatin on the pharmacodynamics of warfarin. J Clin Pharmacol. 1999;39:86-90.
    • (1999) J Clin Pharmacol. , vol.39 , pp. 86-90
    • Lin, J.C.1    Ito, M.K.2    Stolley, S.N.3    Morreale, A.P.4    Marcus, D.B.5
  • 133
    • 33646817390 scopus 로고    scopus 로고
    • The impact of simvastatin on warfarin disposition and dose requirements
    • Sconce EA, Khan TI, Daly AK, Wynne HA, Kamali F. The impact of simvastatin on warfarin disposition and dose requirements. J Thromb Haemost. 2006;4:1422-1424. doi: 10.1111/j.1538-7836.2006.01974.x.
    • (2006) J Thromb Haemost. , vol.4 , pp. 1422-1424
    • Sconce, E.A.1    Khan, T.I.2    Daly, A.K.3    Wynne, H.A.4    Kamali, F.5
  • 134
    • 84861112762 scopus 로고    scopus 로고
    • A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C9 3 allele
    • Andersson ML, Eliasson E, Lindh JD. A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C9 3 allele. Pharmacogenomics. 2012;13:757-762. doi: 10.2217/pgs.12.40.
    • (2012) Pharmacogenomics. , vol.13 , pp. 757-762
    • Andersson, M.L.1    Eliasson, E.2    Lindh, J.D.3
  • 135
    • 34547234102 scopus 로고    scopus 로고
    • Probable warfarin-simvastatin interaction
    • Westergren T, Johansson P, Molden E. Probable warfarin-simvastatin interaction. Ann Pharmacother. 2007;41:1292-1295. doi: 10.1345/aph.1K167.
    • (2007) Ann Pharmacother. , vol.41 , pp. 1292-1295
    • Westergren, T.1    Johansson, P.2    Molden, E.3
  • 136
    • 19244376298 scopus 로고    scopus 로고
    • Potential warfarin-fluvastatin interaction
    • Kline SS, Harrell CC. Potential warfarin-fluvastatin interaction. Ann Pharmacother. 1997;31:790.
    • (1997) Ann Pharmacother. , vol.31 , pp. 790
    • Kline, S.S.1    Harrell, C.C.2
  • 138
    • 1142274350 scopus 로고    scopus 로고
    • Oral anticoagulant drug interactions with statins: Case report of fluvastatin and review of the literature
    • Andrus MR. Oral anticoagulant drug interactions with statins: case report of fluvastatin and review of the literature. Pharmacotherapy. 2004;24:285-290.
    • (2004) Pharmacotherapy. , vol.24 , pp. 285-290
    • Andrus, M.R.1
  • 139
    • 0025173199 scopus 로고
    • Lovastatin: Warfarin interaction
    • Ahmad S. Lovastatin: warfarin interaction. Arch Intern Med. 1990;150:2407.
    • (1990) Arch Intern Med. , vol.150 , pp. 2407
    • Ahmad, S.1
  • 140
    • 0942300658 scopus 로고    scopus 로고
    • Rosuvastatin-warfarin drug interaction
    • Barry M. Rosuvastatin-warfarin drug interaction. Lancet. 2004;363:328. doi: 10.1016/S0140-6736(03)15396-2.
    • (2004) Lancet. , vol.363 , pp. 328
    • Barry, M.1
  • 142
    • 84856429823 scopus 로고    scopus 로고
    • Effect of pitavastatin vs rosuvastatin on international normalized ratio in healthy volunteers on steadystate warfarin
    • Yu CY, Campbell SE, Zhu B, Knadler MP, Small DS, Sponseller CA, Hunt TL, Morgan RE. Effect of pitavastatin vs. rosuvastatin on international normalized ratio in healthy volunteers on steadystate warfarin. Curr Med Res Opin. 2012;28:187-194. doi: 10.1185/03007995.2011.648264.
    • (2012) Curr Med Res Opin. , vol.28 , pp. 187-194
    • Yu, C.Y.1    Campbell, S.E.2    Zhu, B.3    Knadler, M.P.4    Small, D.S.5    Sponseller, C.A.6    Hunt, T.L.7    Morgan, R.E.8
  • 143
    • 33748097815 scopus 로고    scopus 로고
    • Pharmacodynamic evaluation of warfarin and rosuvastatin co-administration in healthy subjects
    • Jindal D, Tandon M, Sharma S, Pillai KK. Pharmacodynamic evaluation of warfarin and rosuvastatin co-administration in healthy subjects. Eur J Clin Pharmacol. 2005;61:621-625. doi: 10.1007/s00228-005-0986-6.
    • (2005) Eur J Clin Pharmacol. , vol.61 , pp. 621-625
    • Jindal, D.1    Tandon, M.2    Sharma, S.3    Pillai, K.K.4
  • 144
    • 0030784620 scopus 로고    scopus 로고
    • Atorvastatin does not alter the anticoagulant activity of warfarin
    • Stern R, Abel R, Gibson GL, Besserer J. Atorvastatin does not alter the anticoagulant activity of warfarin. J Clin Pharmacol. 1997;37:1062-1064.
    • (1997) J Clin Pharmacol. , vol.37 , pp. 1062-1064
    • Stern, R.1    Abel, R.2    Gibson, G.L.3    Besserer, J.4
  • 146
    • 84876205079 scopus 로고    scopus 로고
    • Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers
    • Teng R, Mitchell PD, Butler KA. Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers. Eur J Clin Pharmacol. 2013;69:477-487. doi: 10.1007/s00228-012-1369-4.
    • (2013) Eur J Clin Pharmacol. , vol.69 , pp. 477-487
    • Teng, R.1    Mitchell, P.D.2    Butler, K.A.3
  • 147
    • 84873580229 scopus 로고    scopus 로고
    • Exploring the ticagrelor-statin interplay in the PLATO trial
    • Dinicolantonio JJ, Serebruany VL. Exploring the ticagrelor-statin interplay in the PLATO trial. Cardiology. 2013;124:105-107. doi: 10.1159/000346151.
    • (2013) Cardiology. , vol.124 , pp. 105-107
    • Dinicolantonio, J.J.1    Serebruany, V.L.2
  • 151
    • 84996428271 scopus 로고    scopus 로고
    • Accessed August 28
    • Otsuka. Tolvaptan [package insert]. http://www.otsuka-us.com/ products/Documents/Samsca.PI.pdf. Accessed August 28, 2016.
    • (2016) Tolvaptan [Package Insert
  • 155
  • 158
    • 12344325443 scopus 로고    scopus 로고
    • Drug therapy in the heart transplant recipient, part IV: Drug-drug interactions
    • Page RL 2nd, Miller GG, Lindenfeld J. Drug therapy in the heart transplant recipient, part IV: drug-drug interactions. Circulation. 2005;111:230-239. doi: 10.1161/01. CIR.0000151805.86933.35.
    • (2005) Circulation. , vol.111 , pp. 230-239
    • Page, I.I.R.L.1    Miller, G.G.2    Lindenfeld, J.3
  • 159
    • 0030042485 scopus 로고    scopus 로고
    • Clinically significant drug interactions with cyclosporine: An update
    • Campana C, Regazzi MB, Buggia I, Molinaro M. Clinically significant drug interactions with cyclosporine: an update. Clin Pharmacokinet. 1996;30:141-179.
    • (1996) Clin Pharmacokinet. , vol.30 , pp. 141-179
    • Campana, C.1    Regazzi, M.B.2    Buggia, I.3    Molinaro, M.4
  • 161
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipidlowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT. Drug interactions with lipidlowering drugs: mechanisms and clinical relevance. Clin Pharmacol Ther. 2006;80:565-581. doi: 10.1016/j.clpt.2006.09.003.
    • (2006) Clin Pharmacol Ther. , vol.80 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 164
  • 165
    • 58849117190 scopus 로고    scopus 로고
    • Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation
    • Aliabadi AZ, Mahr S, Dunkler D, Grömmer M, Zimpfer D, Wolner E, Grimm M, Zuckermann AO. Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation. Transplantation. 2008;86:1771-1776. doi: 10.1097/TP.0b013e3181910eb2.
    • (2008) Transplantation. , vol.86 , pp. 1771-1776
    • Aliabadi, A.Z.1    Mahr, S.2    Dunkler, D.3    Grömmer, M.4    Zimpfer, D.5    Wolner, E.6    Grimm, M.7    Zuckermann, A.O.8
  • 166
    • 77952977236 scopus 로고    scopus 로고
    • Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient
    • Basic-Jukic N, Kes P, Bubic-Filipi L, Vranjican Z. Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient. Nephrol Dial Transplant. 2010;25:2036; author reply 2036-2037. doi: 10.1093/ ndt/gfq157.
    • (2010) Nephrol Dial Transplant. , vol.25 , pp. 2036-2037
    • Basic-Jukic, N.1    Kes, P.2    Bubic-Filipi, L.3    Vranjican, Z.4
  • 167
    • 64349118448 scopus 로고    scopus 로고
    • Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin with rapamycin plus tacrolimus in liver transplant patient
    • Dopazo C, Bilbao I, Lázaro JL, Sapisochin G, Caralt M, Blanco L, Castells L, Charco R. Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin with rapamycin plus tacrolimus in liver transplant patient. Transplant Proc. 2009;41: 1021-1024. doi: 10.1016/j.transproceed.2009.02.019.
    • (2009) Transplant Proc. , vol.41 , pp. 1021-1024
    • Dopazo, C.1    Bilbao, I.2    Lázaro, J.L.3    Sapisochin, G.4    Caralt, M.5    Blanco, L.6    Castells, L.7    Charco, R.8
  • 169
    • 84872678868 scopus 로고    scopus 로고
    • Lowdose colchicine for secondary prevention of cardiovascular disease
    • Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Lowdose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol. 2013;61:404-410. doi: 10.1016/j. jacc.2012.10.027.
    • (2013) J Am Coll Cardiol. , vol.61 , pp. 404-410
    • Nidorf, S.M.1    Eikelboom, J.W.2    Budgeon, C.A.3    Thompson, P.L.4
  • 170
    • 10044225589 scopus 로고    scopus 로고
    • Cytoskeletal myotoxicity from simvastatin and colchicine
    • Baker SK, Goodwin S, Sur M, Tarnopolsky MA. Cytoskeletal myotoxicity from simvastatin and colchicine. Muscle Nerve. 2004;30:799-802. doi: 10.1002/mus.20135.
    • (2004) Muscle Nerve. , vol.30 , pp. 799-802
    • Baker, S.K.1    Goodwin, S.2    Sur, M.3    Tarnopolsky, M.A.4
  • 172
    • 37249063052 scopus 로고    scopus 로고
    • Which statin should be used together with colchicine? Clinical experience in three patients with nephrotic syndrome due to AA type amyloidosis
    • Sahin G, Korkmaz C, Yalcin AU. Which statin should be used together with colchicine? Clinical experience in three patients with nephrotic syndrome due to AA type amyloidosis. Rheumatol Int. 2008;28:289-291. doi: 10.1007/s00296-007-0435-1.
    • (2008) Rheumatol Int. , vol.28 , pp. 289-291
    • Sahin, G.1    Korkmaz, C.2    Yalcin, A.U.3
  • 173
    • 77958601194 scopus 로고    scopus 로고
    • Multiple organ failure after an overdose of less than 0.4 mg/ kg of colchicine: Role of coingestants and drugs during intensive care management
    • Montiel V, Huberlant V, Vincent MF, Bonbled F, Hantson P. Multiple organ failure after an overdose of less than 0.4 mg/ kg of colchicine: role of coingestants and drugs during intensive care management. Clin Toxicol (Phila). 2010;48:845-848. doi: 10.3109/15563650.2010.509101.
    • (2010) Clin Toxicol (Phila). , vol.48 , pp. 845-848
    • Montiel, V.1    Huberlant, V.2    Vincent, M.F.3    Bonbled, F.4    Hantson, P.5
  • 174
    • 21744439979 scopus 로고    scopus 로고
    • Possible colchicine rhabdomyolysis in a fluvastatin-treated patient
    • Atasoyu EM, Evrenkaya TR, Solmazgul E. Possible colchicine rhabdomyolysis in a fluvastatin-treated patient. Ann Pharmacother. 2005;39:1368-1369. doi: 10.1345/aph.1E653.
    • (2005) Ann Pharmacother. , vol.39 , pp. 1368-1369
    • Atasoyu, E.M.1    Evrenkaya, T.R.2    Solmazgul, E.3
  • 175
    • 78149239391 scopus 로고    scopus 로고
    • Rhabdomyolysis induced by co-administration of fluvastatin and colchicine
    • Sarullo FM, Americo L, Di Franco A, Di Pasquale P. Rhabdomyolysis induced by co-administration of fluvastatin and colchicine. Monaldi Arch Chest Dis. 2010;74:147-149. doi: 10.4081/monaldi.2010.264.
    • (2010) Monaldi Arch Chest Dis. , vol.74 , pp. 147-149
    • Sarullo, F.M.1    Americo, L.2    Di Franco, A.3    Di Pasquale, P.4
  • 176
    • 33845199216 scopus 로고    scopus 로고
    • Colchicine and HMG Co-A reductase inhibitors induced myopathy: A case report
    • Torgovnick J, Sethi N, Arsura E. Colchicine and HMG Co-A reductase inhibitors induced myopathy: a case report. Neurotoxicology. 2006;27:1126-1127. doi: 10.1016/j.neuro.2006.09.003.
    • (2006) Neurotoxicology. , vol.27 , pp. 1126-1127
    • Torgovnick, J.1    Sethi, N.2    Arsura, E.3
  • 177
    • 21744447883 scopus 로고    scopus 로고
    • Acute myopathy in a patient with concomitant use of pravastatin and colchicine
    • Alayli G, Cengiz K, Cantürk F, Durmuş D, Akyol Y, Menekşe EB. Acute myopathy in a patient with concomitant use of pravastatin and colchicine. Ann Pharmacother. 2005;39:1358-1361. doi: 10.1345/aph.1E593.
    • (2005) Ann Pharmacother. , vol.39 , pp. 1358-1361
    • Alayli, G.1    Cengiz, K.2    Cantürk, F.3    Durmuş, D.4    Akyol, Y.5    Menekşe, E.B.6
  • 178
    • 78651367718 scopus 로고    scopus 로고
    • Colchicine-induced rhabdomyolysis in a heart/lung transplant patient with concurrent use of cyclosporin, pravastatin, and azithromycin
    • Bouquié R, Deslandes G, Renaud C, Dailly E, Haloun A, Jolliet P. Colchicine-induced rhabdomyolysis in a heart/lung transplant patient with concurrent use of cyclosporin, pravastatin, and azithromycin. J Clin Rheumatol. 2011;17:28-30. doi: 10.1097/ RHU.0b013e3182056042.
    • (2011) J Clin Rheumatol. , vol.17 , pp. 28-30
    • Bouquié, R.1    Deslandes, G.2    Renaud, C.3    Dailly, E.4    Haloun, A.5    Jolliet, P.6
  • 179
    • 0036709325 scopus 로고    scopus 로고
    • Colchicine-induced acute myopathy in a patient with concomitant use of simvastatin
    • Hsu WC, Chen WH, Chang MT, Chiu HC. Colchicine-induced acute myopathy in a patient with concomitant use of simvastatin. Clin Neuropharmacol. 2002;25:266-268.
    • (2002) Clin Neuropharmacol. , vol.25 , pp. 266-268
    • Hsu, W.C.1    Chen, W.H.2    Chang, M.T.3    Chiu, H.C.4
  • 180
    • 36549086091 scopus 로고    scopus 로고
    • Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin
    • Francis L, Bonilla E, Soforo E, Neupane H, Nakhla H, Fuller C, Perl A. Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin. Clin Rheumatol. 2008;27:129-131. doi: 10.1007/ s10067-007-0696-9.
    • (2008) Clin Rheumatol. , vol.27 , pp. 129-131
    • Francis, L.1    Bonilla, E.2    Soforo, E.3    Neupane, H.4    Nakhla, H.5    Fuller, C.6    Perl, A.7
  • 181
    • 35148864034 scopus 로고    scopus 로고
    • Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine
    • Justiniano M, Dold S, Espinoza LR. Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine. J Clin Rheumatol. 2007;13:266-268. doi: 10.1097/RHU.0b013e318156d977.
    • (2007) J Clin Rheumatol. , vol.13 , pp. 266-268
    • Justiniano, M.1    Dold, S.2    Espinoza, L.R.3
  • 182
    • 84871895162 scopus 로고    scopus 로고
    • Myopathy and possible intestinal dysfunction in a patient treated with colchicine and simvastatin
    • Oh DH, Chan SQ, Wilson AM. Myopathy and possible intestinal dysfunction in a patient treated with colchicine and simvastatin. Med J Aust. 2012;197:332-333.
    • (2012) Med J Aust. , vol.197 , pp. 332-333
    • Oh, D.H.1    Chan, S.Q.2    Wilson, A.M.3
  • 183
    • 77956612624 scopus 로고    scopus 로고
    • Ivabradine and outcomes in chronic heart failure (SHIFT): A randomised placebo-controlled study [published correction appears in Lancet 2010;376:1988
    • Swedberg K, Komajda M, Böhm M, Borer JS, Ford I, Dubost-Brama A, Lerebours G, Tavazzi L; SHIFT Investigators. Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study [published correction appears in Lancet. 2010;376:1988]. Lancet. 2010;376:875-885. doi: 10.1016/ S0140-6736(10)61198-1.
    • (2010) Lancet. , vol.376 , pp. 875-885
    • Swedberg, K.1    Komajda, M.2    Böhm, M.3    Borer, J.S.4    Ford, I.5    Dubost-Brama, A.6    Lerebours, G.7    Tavazzi, L.8
  • 185
  • 187
    • 84996455228 scopus 로고    scopus 로고
    • Accessed April 21
    • European Medicines Agency. Assessment report: Entresto. 2015. http://www.ema.europa.eu/docs/en-GB/document-library/ EPAR-Public-assessment-report/human/004062/ WC500197538.pdf. Accessed April 21, 2016.
    • (2016) Assessment Report: Entresto. 2015
    • European Medicines Agency1
  • 189
    • 84996447629 scopus 로고    scopus 로고
    • Accessed August 28
    • http://www.hiv-druginteractions.org/. Accessed August 28, 2016.
    • (2016)


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