Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: Results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects with Chronic Stable Angina)

Journal of the American College of Cardiology

Volumn 61, Issue 20, 2013, Pages 2038-2045

  Kosiborod, Mikhail ^a,b   Arnold, Suzanne V ^a,b   Spertus, John A ^a,b   McGuire, Darren K ^c   Li, Yan ^a   Yue, Patrick ^d   Ben Yehuda, Ori ^d   Katz, Amos ^e   Jones, Philip G ^a   Olmsted, Ann ^d   Belardinelli, Luiz ^d   Chaitman, Bernard R ^f  

^a SAINT LUKE S MID AMERICA HEART INSTITUTE   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d GILEAD SCIENCES   (United States)

^e BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^f SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

clinical trial; coronary artery disease; diabetes; ranolazine; stable angina

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIDIABETIC AGENT; ANTITHROMBOCYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DILTIAZEM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCERYL TRINITRATE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRIC ACID DERIVATIVE; PLACEBO; RANOLAZINE; VERAPAMIL;

ADULT; ARTICLE; CEREBROVASCULAR ACCIDENT; CONSTIPATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIASTOLIC BLOOD PRESSURE; DISEASE DURATION; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG ACTIVITY; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; GLYCEMIC CONTROL; HEART DEATH; HEART FAILURE; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; NAUSEA; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SHORT FORM 36; STABLE ANGINA PECTORIS; SYSTOLIC BLOOD PRESSURE; TRANSIENT ISCHEMIC ATTACK;

ACETANILIDES; AGED; ANGINA, STABLE; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; DOUBLE-BLIND METHOD; ENZYME INHIBITORS; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; MIDDLE AGED; NITROGLYCERIN; PIPERAZINES; SODIUM CHANNEL BLOCKERS; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 84877776301     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.02.011     Document Type: Article

References (35)

1. A.S. Go, D. Mozaffarian, V.L. Roger Heart disease and stroke statistics - 2013 update: a report from the American Heart Association Circulation 127 2013 e6 e245
2. N. Brown, M. Melville, D. Gray Quality of life four years after acute myocardial infarction: short form 36 scores compared with a normal population Heart 81 1999 352 358
3. B. Brorsson, S.J. Bernstein, R.H. Brook, L. Werko Quality of life of patients with chronic stable angina before and four years after coronary revascularisation compared with a normal population Heart 87 2002 140 145
4. S.V. Arnold, D.A. Morrow, Y. Lei Economic impact of angina after an acute coronary syndrome: insights from the MERLIN-TIMI 36 trial Circ Cardiovasc Qual Outcomes 2 2009 344 353
5. J.F. Beltrame, A.J. Weekes, C. Morgan, R. Tavella, J.A. Spertus The prevalence of weekly angina among patients with chronic stable angina in primary care practices: the Coronary Artery Disease in General Practice (CADENCE) study Arch Intern Med 169 2009 1491 1499
6. T.M. Maddox, K.J. Reid, J.A. Spertus Angina at 1 year after myocardial infarction: prevalence and associated findings Arch Intern Med 168 2008 1310 1316
7. R. Duarte, S. Castela, R.P. Reis Acute coronary syndrome in a diabetic population - risk factors and clinical and angiographic characteristics Rev Port Cardiol 22 2003 1077 1088
8. J. Herlitz, G.B. Wognsen, H. Emanuelsson Mortality and morbidity in diabetic and nondiabetic patients during a 2-year period after coronary artery bypass grafting Diabetes Care 19 1996 698 703
9. P.N. Peterson, J.A. Spertus, D.J. Magid The impact of diabetes on one-year health status outcomes following acute coronary syndromes BMC Cardiovasc Disord 6 2006 41
10. D.A. Morrow, B.M. Scirica, B.R. Chaitman Evaluation of the glycometabolic effects of ranolazine in patients with and without diabetes mellitus in the MERLIN-TIMI 36 randomized controlled trial Circulation 119 2009 2032 2039
11. C. Antzelevitch, L. Belardinelli, A.C. Zygmunt Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties Circulation 110 2004 904 910
12. B.R. Chaitman, S.L. Skettino, J.O. Parker Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina J Am Coll Cardiol 43 2004 1375 1382
13. M.F. Rousseau, H. Pouleur, G. Cocco, A.A. Wolff Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris Am J Cardiol 95 2005 311 316
14. B.R. Chaitman, C.J. Pepine, J.O. Parker Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial JAMA 291 2004 309 316
15. P.H. Stone, N.A. Gratsiansky, A. Blokhin, I.Z. Huang, L. Meng Antianginal efficacy of ranolazine when added to treatment with amlodipine: the ERICA (Efficacy of Ranolazine in Chronic Angina) trial J Am Coll Cardiol 48 2006 566 575
16. J.W. Chisholm, A.B. Goldfine, A.K. Dhalla Effect of ranolazine on A1C and glucose levels in hyperglycemic patients with non-ST elevation acute coronary syndrome Diabetes Care 33 2010 1163 1168
17. A.D. Timmis, B.R. Chaitman, M. Crager Effects of ranolazine on exercise tolerance and HbA1c in patients with chronic angina and diabetes Eur Heart J 27 2006 42 48
18. J.E. Ware Jr., C.D. Sherbourne The MOS 36-item short-form health survey (SF-36) I. Conceptual framework and item selection Med Care 30 1992 473 483
19. W. Guy ECDEU Assessment Manual for Psychopharmacology (DHEW Publication No. ADM 76-338) 1976 U.S. Government Printing Office Washington, DC
20. S.M. Haffner, S. Lehto, T. Ronnemaa, K. Pyorala, M. Laakso Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction N Engl J Med 339 1998 229 234
21. S.M. Donahoe, G.C. Stewart, C.H. McCabe Diabetes and mortality following acute coronary syndromes JAMA 298 2007 765 775
22. B. Marchant, V. Umachandran, R. Stevenson, P.G. Kopelman, A.D. Timmis Silent myocardial ischemia: role of subclinical neuropathy in patients with and without diabetes J Am Coll Cardiol 22 1993 1433 1437
23. D.P. Murray, T. O'Brien, R. Mulrooney, D.J. O'Sullivan Autonomic dysfunction and silent myocardial ischaemia on exercise testing in diabetes mellitus Diabet Med 7 1990 580 584
24. M. Chiariello, C. Indolfi, M.R. Cotecchia, C. Sifola, M. Romano, M. Condorelli Asymptomatic transient ST changes during ambulatory ECG monitoring in diabetic patients Am Heart J 110 1985 529 534
25. S. Nishio, Y. Teshima, N. Takahashi Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart J Mol Cell Cardiol 52 2012 1103 1111
26. O.M. Koval, J.S. Snyder, R.M. Wolf Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease Circulation 126 2012 2084 2094
27. L. Yao, P. Fan, Z. Jiang Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice Am J Physiol Cell Physiol 301 2011 C577 C586
28. P. Deedwania, M. Kosiborod, E. Barrett Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism Circulation 117 2008 1610 1619
29. G. Jackson, J. Schwartz, R.E. Kates, M. Winchester, D.C. Harrison Atenolol: once-daily cardioselective beta blockade for angina pectoris Circulation 61 1980 555 560
30. R. Weiss, D. Ferry, E. Pickering Effectiveness of three different doses of carvedilol for exertional angina Carvedilol-Angina Study Group Am J Cardiol 82 1998 927 931
31. J.N. Estrada, H. Saglietti, M. Di Marco, H. Casabe, R. Oliveri Antiischemic properties of amlodipine, a new calcium antagonist, in patients with severe coronary artery disease: a prospective trial Am Heart J 118 1989 1130 1132
32. J.C. Tardif, P. Ponikowski, T. Kahan Efficacy of the I(f) current inhibitor ivabradine in patients with chronic stable angina receiving beta-blocker therapy: a 4-month, randomized, placebo-controlled trial Eur Heart J 30 2009 540 548
33. W.H. Frishman, M. Heiman Usefulness of oral nisoldipine for stable angina pectoris The Nisoldipine Multicenter Angina Study Group Am J Cardiol 68 1991 1004 1009
34. A.A. Stone, S. Shiffman, J.E. Schwartz, J.E. Broderick, M.R. Hufford Patient non-compliance with paper diaries BMJ 324 2002 1193 1194
35. S.V. Arnold, D.A. Morrow, K. Wang Effects of ranolazine on disease-specific health status and quality of life among patients with acute coronary syndromes: results from the MERLIN-TIMI 36 randomized trial Circ Cardiovasc Qual Outcomes 1 2008 107 115