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Volumn 6, Issue , 2016, Pages

Regulatory T cells, especially ICOS+ FOXP3+ regulatory T cells, are increased in the hepatocellular carcinoma microenvironment and predict reduced survival

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; ICOS PROTEIN, HUMAN; INDUCIBLE T CELL COSTIMULATOR;

EID: 84991501368     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep35056     Document Type: Article
Times cited : (110)

References (32)
  • 1
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Forner, A., Llovet, J. M., & Bruix, J. Hepatocellular carcinoma. Lancet 379, 1245-1255 (2012
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 2
    • 0042738929 scopus 로고    scopus 로고
    • Twenty-year trends of primary liver cancer incidence rates in an urban Chinese population
    • Hao, X. S., et al. Twenty-year trends of primary liver cancer incidence rates in an urban Chinese population. Eur J Cancer Prev 12, 273-279 (2003
    • (2003) Eur J Cancer Prev , vol.12 , pp. 273-279
    • Hao, X.S.1
  • 3
    • 33747029250 scopus 로고    scopus 로고
    • Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
    • Budhu, A., et al. Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 10, 99-111 (2006
    • (2006) Cancer Cell , vol.10 , pp. 99-111
    • Budhu, A.1
  • 4
    • 77950346282 scopus 로고    scopus 로고
    • Immunity inflammation, and cancer
    • Grivennikov, S. I., Greten, F. R., & Karin, M. Immunity, inflammation, and cancer. Cell 140, 883-899 (2010
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 5
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon, J., et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313, 1960-1964 (2006
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1
  • 6
    • 79955038372 scopus 로고    scopus 로고
    • Pillars article: Immunologic self-Tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-Tolerance causes various autoimmune diseases
    • J. Immunol 1995
    • Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., & Toda, M. Pillars article: immunologic self-Tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-Tolerance causes various autoimmune diseases. J. Immunol. 1995. J Immunol 186, 3808-3821 (2011
    • (2011) J Immunol , vol.186 , pp. 3808-3821
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 7
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • Beyer, M., & Schultze, J. L. Regulatory T cells in cancer. Blood 108, 804-811 (2006
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 8
    • 2942674466 scopus 로고    scopus 로고
    • Foxp3: A critical regulator of the development, and function of regulatory T cells
    • Hori, S., & Sakaguchi, S. Foxp3: a critical regulator of the development, and function of regulatory T cells. Microbes Infect 6, 745-751 (2004
    • (2004) Microbes Infect , vol.6 , pp. 745-751
    • Hori, S.1    Sakaguchi, S.2
  • 9
    • 0037099733 scopus 로고    scopus 로고
    • Human CD4(+ )CD25(+ ) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected
    • Dieckmann, D., Bruett, C. H., Ploettner, H., Lutz, M. B., & Schuler, G. Human CD4(+ )CD25(+ ) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med 196, 247-253 (2002
    • (2002) J Exp Med , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 10
    • 33646052605 scopus 로고    scopus 로고
    • Functional study of CD4+ CD25+ regulatory T cells in health, and autoimmune hepatitis
    • Longhi, M. S., et al. Functional study of CD4+ CD25+ regulatory T cells in health, and autoimmune hepatitis. J Immunol 176, 4484-4491 (2006
    • (2006) J Immunol , vol.176 , pp. 4484-4491
    • Longhi, M.S.1
  • 11
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
    • Wolf, D., et al. The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res 11, 8326-8331 (2005
    • (2005) Clin Cancer Res , vol.11 , pp. 8326-8331
    • Wolf, D.1
  • 12
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege, and predicts reduced survival
    • Curiel, T. J., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege, and predicts reduced survival. Nat Med 10, 942-949 (2004
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1
  • 13
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood, and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage, U. K., et al. Prevalence of regulatory T cells is increased in peripheral blood, and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 169, 2756-2761 (2002
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1
  • 14
    • 33750807427 scopus 로고    scopus 로고
    • CD4+ CD25high T cells are enriched in the tumor, and peripheral blood of prostate cancer patients
    • Miller, A. M., et al. CD4+ CD25high T cells are enriched in the tumor, and peripheral blood of prostate cancer patients. J Immunol 177, 7398-7405 (2006
    • (2006) J Immunol , vol.177 , pp. 7398-7405
    • Miller, A.M.1
  • 15
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4(+ )CD25(+ ) T cells in tumors from patients with early-stage non-small cell lung cancer, and latestage ovarian cancer
    • Woo, E. Y., et al. Regulatory CD4(+ )CD25(+ ) T cells in tumors from patients with early-stage non-small cell lung cancer, and latestage ovarian cancer. Cancer Res 61, 4766-4772 (2001
    • (2001) Cancer Res , vol.61 , pp. 4766-4772
    • Woo, E.Y.1
  • 16
    • 0041386189 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells in patients with gastrointestinal malignancies: Possible involvement of regulatory T cells in disease progression
    • Sasada, T., Kimura, M., Yoshida, Y., Kanai, M., & Takabayashi, A. CD4+ CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression. Cancer 98, 1089-1099 (2003
    • (2003) Cancer , vol.98 , pp. 1089-1099
    • Sasada, T.1    Kimura, M.2    Yoshida, Y.3    Kanai, M.4    Takabayashi, A.5
  • 17
    • 33744457276 scopus 로고    scopus 로고
    • CD4(+ )CD25high regulatory T cells increase with tumor stage in patients with gastric, and esophageal cancers
    • Kono, K., et al. CD4(+ )CD25high regulatory T cells increase with tumor stage in patients with gastric, and esophageal cancers. Cancer Immunol Immunother 55, 1064-1071 (2006
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1064-1071
    • Kono, K.1
  • 18
    • 84860762023 scopus 로고    scopus 로고
    • Phenotypical analysis of lymphocytes with suppressive, and regulatory properties (Tregs), and NK cells in the papillary carcinoma of thyroid
    • Gogali, F., et al. Phenotypical analysis of lymphocytes with suppressive, and regulatory properties (Tregs), and NK cells in the papillary carcinoma of thyroid. J Clin Endocrinol Metab 97, 1474-1482 (2012
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1474-1482
    • Gogali, F.1
  • 19
    • 84856585744 scopus 로고    scopus 로고
    • ICOS-dependent homeostasis, and function of Foxp3+ regulatory T cells in islets of nonobese diabetic mice
    • Kornete, M., Sgouroudis, E., & Piccirillo, C. A. ICOS-dependent homeostasis, and function of Foxp3+ regulatory T cells in islets of nonobese diabetic mice. J Immunol 188, 1064-1074 (2012
    • (2012) J Immunol , vol.188 , pp. 1064-1074
    • Kornete, M.1    Sgouroudis, E.2    Piccirillo, C.A.3
  • 20
    • 49149125958 scopus 로고    scopus 로고
    • Expression of ICOS on human melanoma-infiltrating CD4+ CD25highFoxp3+ T regulatory cells: Implications, and impact on tumor-mediated immune suppression
    • Strauss, L., et al. Expression of ICOS on human melanoma-infiltrating CD4+ CD25highFoxp3+ T regulatory cells: implications, and impact on tumor-mediated immune suppression. J Immunol 180, 2967-2980 (2008
    • (2008) J Immunol , vol.180 , pp. 2967-2980
    • Strauss, L.1
  • 21
    • 84893782730 scopus 로고    scopus 로고
    • Role of plasmacytoid dendritic cells, and inducible costimulator-positive regulatory T cells in the immunosuppression microenvironment of gastric cancer
    • Huang, X. M., et al. Role of plasmacytoid dendritic cells, and inducible costimulator-positive regulatory T cells in the immunosuppression microenvironment of gastric cancer. Cancer Sci 105, 150-158 (2014
    • (2014) Cancer Sci , vol.105 , pp. 150-158
    • Huang, X.M.1
  • 22
    • 84881150970 scopus 로고    scopus 로고
    • Regulatory T cells, and plasmacytoid dendritic cells contribute to the immune escape of papillary thyroid cancer coexisting with multinodular non-Toxic goiter
    • Yu, H., et al. Regulatory T cells, and plasmacytoid dendritic cells contribute to the immune escape of papillary thyroid cancer coexisting with multinodular non-Toxic goiter. Endocrine 44, 172-181 (2013
    • (2013) Endocrine , vol.44 , pp. 172-181
    • Yu, H.1
  • 23
    • 84870666902 scopus 로고    scopus 로고
    • Intratumoral regulatory T cells alone or in combination with cytotoxic T cells predict prognosis of hepatocellular carcinoma after resection
    • Chen, K. J., et al. Intratumoral regulatory T cells alone or in combination with cytotoxic T cells predict prognosis of hepatocellular carcinoma after resection. Med Oncol 29, 1817-1826 (2012
    • (2012) Med Oncol , vol.29 , pp. 1817-1826
    • Chen, K.J.1
  • 24
    • 0031890627 scopus 로고    scopus 로고
    • Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration
    • Wada, Y., Nakashima, O., Kutami, R., Yamamoto, O., & Kojiro, M. Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration. Hepatology 27, 407-414 (1998
    • (1998) Hepatology , vol.27 , pp. 407-414
    • Wada, Y.1    Nakashima, O.2    Kutami, R.3    Yamamoto, O.4    Kojiro, M.5
  • 25
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory, and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Gao, Q., et al. Intratumoral balance of regulatory, and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol 25, 2586-2593 (2007
    • (2007) J Clin Oncol , vol.25 , pp. 2586-2593
    • Gao, Q.1
  • 26
    • 33847384529 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells affect the development, and progression of hepatocarcinogenesis
    • Kobayashi, N., et al. FOXP3+ regulatory T cells affect the development, and progression of hepatocarcinogenesis. Clin Cancer Res 13, 902-911 (2007
    • (2007) Clin Cancer Res , vol.13 , pp. 902-911
    • Kobayashi, N.1
  • 27
    • 84878854019 scopus 로고    scopus 로고
    • Prediction of recurrence, and survival in hepatocellular carcinoma based on two Cox models mainly determined by FoxP3+ regulatory T cells
    • Lin, S. Z., et al. Prediction of recurrence, and survival in hepatocellular carcinoma based on two Cox models mainly determined by FoxP3+ regulatory T cells. Cancer Prev Res (Phila) 6, 594-602 (2013
    • (2013) Cancer Prev Res (Phila , vol.6 , pp. 594-602
    • Lin, S.Z.1
  • 28
    • 79958845363 scopus 로고    scopus 로고
    • Tumor-infiltrating immune cells, and prognosis: The potential link between conventional cancer therapy, and immunity
    • Jochems, C., & Schlom, J. Tumor-infiltrating immune cells, and prognosis: the potential link between conventional cancer therapy, and immunity. Exp Biol Med (Maywood) 236, 567-579 (2011
    • (2011) Exp Biol Med (Maywood , vol.236 , pp. 567-579
    • Jochems, C.1    Schlom, J.2
  • 29
    • 84870299577 scopus 로고    scopus 로고
    • Tumor-infiltrating FoxP3+ Tregs, and CD8+ T cells affect the prognosis of hepatocellular carcinoma patients
    • Huang, Y., et al. Tumor-infiltrating FoxP3+ Tregs, and CD8+ T cells affect the prognosis of hepatocellular carcinoma patients. Digestion 86, 329-337 (2012
    • (2012) Digestion , vol.86 , pp. 329-337
    • Huang, Y.1
  • 31
    • 65249175159 scopus 로고    scopus 로고
    • C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
    • Reboldi, A., et al. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol 10, 514-523 (2009
    • (2009) Nat Immunol , vol.10 , pp. 514-523
    • Reboldi, A.1
  • 32
    • 50049123401 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Sallusto, F., & Baggiolini, M. Chemokines, and leukocyte traffic. Nat Immunol 9, 949-952 (2008
    • (2008) Nat Immunol , vol.9 , pp. 949-952
    • Sallusto, F.1    Baggiolini, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.