메뉴 건너뛰기




Volumn 29, Issue 3, 2012, Pages 1817-1826

Intratumoral regulatory T cells alone or in combination with cytotoxic T cells predict prognosis of hepatocellular carcinoma after resection

Author keywords

Cytotoxic T cells, prognosis; Hepatocellular carcinoma; Regulatory T cells; Tumor infiltrating lymphocyte

Indexed keywords

TRANSCRIPTION FACTOR FOXP3;

EID: 84870666902     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-011-0006-x     Document Type: Article
Times cited : (89)

References (24)
  • 1
    • 79958845363 scopus 로고    scopus 로고
    • Tumor-infiltrating immune cells and prognosis: The potential link between conventional cancer therapy and immunity
    • doi:10.1258/ebm.2011.011007
    • Jochems C, Schlom J. Tumor-infiltrating immune cells and prognosis: the potential link between conventional cancer therapy and immunity. Exp Biol Med (Maywood). 2011;236(5):567-79. doi:10.1258/ebm.2011.011007.
    • (2011) Exp Biol Med (Maywood) , vol.236 , Issue.5 , pp. 567-79
    • Jochems, C.1    Schlom, J.2
  • 2
    • 0031890627 scopus 로고    scopus 로고
    • Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration
    • doi: 10.1002/hep.510270214
    • Wada Y, Nakashima O, Kutami R, Yamamoto O, Kojiro M. Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration. Hepatology. 1998;27(2):407-14. doi: 10.1002/hep.510270214.
    • (1998) Hepatology , vol.27 , Issue.2 , pp. 407-14
    • Wada, Y.1    Nakashima, O.2    Kutami, R.3    Yamamoto, O.4    Kojiro, M.5
  • 3
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • doi:10.1126/science.1129139
    • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science. 2006;313(5795):1960-4. doi:10.1126/science.1129139.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1960-4
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6
  • 4
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol. 2006;6(4):295-307.
    • (2006) Nat Rev Immunol , vol.6 , Issue.4 , pp. 295-307
    • Zou, W.1
  • 5
    • 34250005419 scopus 로고    scopus 로고
    • Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
    • Fu J, Xu D, Liu Z, Shi M, Zhao P, Fu B, et al. Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology. 2007;132(7):2328-39.
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2328-39
    • Fu, J.1    Xu, D.2    Liu, Z.3    Shi, M.4    Zhao, P.5    Fu, B.6
  • 6
    • 16244393380 scopus 로고    scopus 로고
    • Compromised lymphocytes infiltrate hepatocellular carcinoma: The role of T-regulatory cells
    • Unitt E, Rushbrook SM, Marshall A, Davies S, Gibbs P, Morris LS, et al. Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells. Hepatology. 2005;41(4) :722-30.
    • (2005) Hepatology , vol.41 , Issue.4 , pp. 722-30
    • Unitt, E.1    Rushbrook, S.M.2    Marshall, A.3    Davies, S.4    Gibbs, P.5    Morris, L.S.6
  • 7
    • 33745699342 scopus 로고    scopus 로고
    • Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma
    • Yang XH, Yamagiwa S, Ichida T, Matsuda Y, Sugahara S, Watanabe H, et al. Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma. J Hepatol. 2006;45(2):254-62.
    • (2006) J Hepatol , vol.45 , Issue.2 , pp. 254-62
    • Yang, X.H.1    Yamagiwa, S.2    Ichida, T.3    Matsuda, Y.4    Sugahara, S.5    Watanabe, H.6
  • 8
    • 65949111746 scopus 로고    scopus 로고
    • FOXP3 defines regulatory T cells in human tumor and autoimmune disease
    • Kryczek I, Liu R, Wang G, Wu K, Shu X, Szeliga W, et al. FOXP3 defines regulatory T cells in human tumor and autoimmune disease. Cancer Res. 2009;69(9):3995-4000.
    • (2009) Cancer Res , vol.69 , Issue.9 , pp. 3995-4000
    • Kryczek, I.1    Liu, R.2    Wang, G.3    Wu, K.4    Shu, X.5    Szeliga, W.6
  • 9
    • 58249089749 scopus 로고    scopus 로고
    • Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
    • Salama P, Phillips M, Grieu F, Morris M, Zeps N, Joseph D, et al. Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol. 2009; 27(2):186-92.
    • (2009) J Clin Oncol , vol.27 , Issue.2 , pp. 186-92
    • Salama, P.1    Phillips, M.2    Grieu, F.3    Morris, M.4    Zeps, N.5    Joseph, D.6
  • 10
    • 77954704449 scopus 로고    scopus 로고
    • Prognostic significance of regulatory T cells in tumor
    • doi:10.1002/ijc.25464
    • Wilke CM, Wu K, Zhao E, Wang G, Zou W. Prognostic significance of regulatory T cells in tumor. Int J Cancer. 2010;127(4): 748-58. doi:10.1002/ijc.25464.
    • (2010) Int J Cancer , vol.127 , Issue.4 , pp. 748-58
    • Wilke, C.M.1    Wu, K.2    Zhao, E.3    Wang, G.4    Zou, W.5
  • 11
    • 20044367117 scopus 로고    scopus 로고
    • Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells
    • doi:10.1158/1078-0432.CCR-04-1869
    • Alvaro T, Lejeune M, Salvado MT, Bosch R, Garcia JF, Jaen J et al. Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells. Clin Cancer Res. 2005;11(4):1467-73. doi:10.1158/1078-0432.CCR-04-1869.
    • (2005) Clin Cancer Res , vol.11 , Issue.4 , pp. 1467-73
    • Alvaro, T.1    Lejeune, M.2    Salvado, M.T.3    Bosch, R.4    Garcia, J.F.5    Jaen, J.6
  • 12
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Gao Q, Qiu SJ, Fan J, Zhou J, Wang XY, Xiao YS, et al. Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol. 2007;25(18):2586-93.
    • (2007) J Clin Oncol , vol.25 , Issue.18 , pp. 2586-93
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3    Zhou, J.4    Wang, X.Y.5    Xiao, Y.S.6
  • 13
    • 67449095883 scopus 로고    scopus 로고
    • Combination of peritumoral mast cells and T-regulatory cells predicts prognosis of hepatocellular carcinoma
    • doi:10.1111/j.1349-7006.2009.01182.x
    • Ju MJ, Qiu SJ, Gao Q, Fan J, Cai MY, Li YW et al. Combination of peritumoral mast cells and T-regulatory cells predicts prognosis of hepatocellular carcinoma. Cancer Sci. 2009;100(7): 1267-74. doi:10.1111/j.1349- 7006.2009.01182.x.
    • (2009) Cancer Sci , vol.100 , Issue.7 , pp. 1267-74
    • Ju, M.J.1    Qiu, S.J.2    Gao, Q.3    Fan, J.4    Cai, M.Y.5    Li, Y.W.6
  • 14
    • 23944447859 scopus 로고    scopus 로고
    • Comparison between the fifth and sixth editions of the AJCC/UICC TNM staging systems for hepatocellular carcinoma: Multicentric study on 393 cirrhotic resected patients
    • doi:10.1016/j.ejso.2005. 04.008
    • Varotti G, Ramacciato G, Ercolani G, Grazi GL, Vetrone G, Cescon M et al. Comparison between the fifth and sixth editions of the AJCC/UICC TNM staging systems for hepatocellular carcinoma: multicentric study on 393 cirrhotic resected patients. Eur J Surg Oncol. 2005;31(7):760-7. doi:10.1016/j.ejso.2005. 04.008.
    • (2005) Eur J Surg Oncol , vol.31 , Issue.7 , pp. 760-7
    • Varotti, G.1    Ramacciato, G.2    Ercolani, G.3    Grazi, G.L.4    Vetrone, G.5    Cescon, M.6
  • 15
    • 0037790651 scopus 로고    scopus 로고
    • Comparison of MELD, Child-Pugh, and Emory model for the prediction of survival in patients undergoing transjugular intrahepatic portosystemic shunting
    • doi:10.1111/j.1572-0241.2003.07515.x
    • Schepke M, Roth F, Fimmers R, Brensing KA, Sudhop T, Schild HH et al. Comparison of MELD, Child-Pugh, and Emory model for the prediction of survival in patients undergoing transjugular intrahepatic portosystemic shunting. Am J Gastroenterol. 2003;98(5):1167-74. doi:10.1111/j.1572-0241.2003.07515.x.
    • (2003) Am J Gastroenterol , vol.98 , Issue.5 , pp. 1167-74
    • Schepke, M.1    Roth, F.2    Fimmers, R.3    Brensing, K.A.4    Sudhop, T.5    Schild, H.H.6
  • 16
    • 45749137283 scopus 로고    scopus 로고
    • High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma
    • doi:10.1200/JCO.2007.15.6521
    • Zhu XD, Zhang JB, Zhuang PY, Zhu HG, Zhang W, Xiong YQ et al. High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol. 2008;26(16):2707-16. doi:10.1200/JCO.2007.15.6521.
    • (2008) J Clin Oncol , vol.26 , Issue.16 , pp. 2707-16
    • Zhu, X.D.1    Zhang, J.B.2    Zhuang, P.Y.3    Zhu, H.G.4    Zhang, W.5    Xiong, Y.Q.6
  • 17
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10(9):942-9.
    • (2004) Nat Med , vol.10 , Issue.9 , pp. 942-9
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6
  • 18
    • 33749317518 scopus 로고    scopus 로고
    • Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
    • doi:10.1158/1078-0432. CCR-06-0369
    • Hiraoka N, Onozato K, Kosuge T, Hirohashi S. Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions. Clin Cancer Res. 2006;12(18):5423-34. doi:10.1158/1078-0432. CCR-06-0369.
    • (2006) Clin Cancer Res , vol.12 , Issue.18 , pp. 5423-34
    • Hiraoka, N.1    Onozato, K.2    Kosuge, T.3    Hirohashi, S.4
  • 19
    • 31544455880 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating CD4+ T-cell subpopulations in head and neck cancers
    • doi:10.1158/1078-0432.CCR-05-1886
    • Badoual C, Hans S, Rodriguez J, Peyrard S, Klein C, Agueznay Nel H et al. Prognostic value of tumor-infiltrating CD4+ T-cell subpopulations in head and neck cancers. Clin Cancer Res. 2006;12(2):465-72. doi:10.1158/1078-0432.CCR-05- 1886.
    • (2006) Clin Cancer Res , vol.12 , Issue.2 , pp. 465-72
    • Badoual, C.1    Hans, S.2    Rodriguez, J.3    Peyrard, S.4    Klein, C.5    Agueznay Nel, H.6
  • 20
    • 33745215983 scopus 로고    scopus 로고
    • Tumorinfiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma
    • doi:10.1158/1078-0432.CCR-05-2434
    • Grabenbauer GG, Lahmer G, Distel L, Niedobitek G. Tumorinfiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma. Clin Cancer Res. 2006;12(11 Pt 1):3355-60. doi:10.1158/1078- 0432.CCR-05-2434.
    • (2006) Clin Cancer Res , vol.12 , Issue.11 PART 1 , pp. 3355-60
    • Grabenbauer, G.G.1    Lahmer, G.2    Distel, L.3    Niedobitek, G.4
  • 21
    • 33847384529 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis
    • Kobayashi N, Hiraoka N, Yamagami W, Ojima H, Kanai Y, Kosuge T, et al. FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis. Clin Cancer Res. 2007;13(3):902-11.
    • (2007) Clin Cancer Res , vol.13 , Issue.3 , pp. 902-11
    • Kobayashi, N.1    Hiraoka, N.2    Yamagami, W.3    Ojima, H.4    Kanai, Y.5    Kosuge, T.6
  • 22
    • 0037448353 scopus 로고    scopus 로고
    • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
    • doi:10.1056/NEJMoa020177
    • Zhang L, Conejo-Garcia JR, Katsaros D, Gimotty PA, Massobrio M, Regnani G et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med. 2003;348(3):203-13. doi:10.1056/NEJMoa020177
    • (2003) N Engl J Med , vol.348 , Issue.3 , pp. 203-13
    • Zhang, L.1    Conejo-Garcia, J.R.2    Katsaros, D.3    Gimotty, P.A.4    Massobrio, M.5    Regnani, G.6
  • 23
    • 0035394233 scopus 로고    scopus 로고
    • Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: Clinicopathologic demonstration of antitumor immunity
    • Nakano O, Sato M, Naito Y, Suzuki K, Orikasa S, Aizawa M, et al. Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res. 2001;61(13):5132-6.
    • (2001) Cancer Res , vol.61 , Issue.13 , pp. 5132-6
    • Nakano, O.1    Sato, M.2    Naito, Y.3    Suzuki, K.4    Orikasa, S.5    Aizawa, M.6
  • 24
    • 68549136586 scopus 로고    scopus 로고
    • Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients
    • doi:10.1002/ijc.24556
    • Zhou J, Ding T, Pan W, Zhu LY, Li L, Zheng L. Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients. Int J Cancer. 2009;125(7):1640-8. doi:10.1002/ijc.24556.
    • (2009) Int J Cancer , vol.125 , Issue.7 , pp. 1640-8
    • Zhou, J.1    Ding, T.2    Pan, W.3    Zhu, L.Y.4    Li, L.5    Zheng, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.