-
1
-
-
84925487467
-
Enhancing our understanding of current therapies for hepatitis C virus (HCV
-
Gogela NA, Lin MV, Wisocky JL, Chung RT. Enhancing our understanding of current therapies for hepatitis C virus (HCV). Curr HIV/AIDS Rep 2015; 12:68-78.
-
(2015)
Curr HIV/AIDS Rep
, vol.12
, pp. 68-78
-
-
Gogela, N.A.1
Lin, M.V.2
Wisocky, J.L.3
Chung, R.T.4
-
2
-
-
84922526451
-
Homozygosity for HLA group 2 alleles predicts treatment failure with interferonalpha and ribavirin in chronic hepatitis C virus genotype 1 infection
-
Collison M, Chin JL, Abu Shanab A, et al. Homozygosity for HLA group 2 alleles predicts treatment failure with interferonalpha and ribavirin in chronic hepatitis C virus genotype 1 infection. J Interferon Cytokine Res 2015; 35:126-133.
-
(2015)
J Interferon Cytokine Res
, vol.35
, pp. 126-133
-
-
Collison, M.1
Chin, J.L.2
Abu Shanab, A.3
-
3
-
-
84973573737
-
Baseline prevalence and emergence of protease inhibitor resistance mutations following treatment in chronic HCV genotype 1-infected individuals
-
Nguyen LT, Gray E, Dean J, et al. Baseline prevalence and emergence of protease inhibitor resistance mutations following treatment in chronic HCV genotype 1-infected individuals. Antivir Ther 2015; 20:865-869.
-
(2015)
Antivir Ther
, vol.20
, pp. 865-869
-
-
Nguyen, L.T.1
Gray, E.2
Dean, J.3
-
4
-
-
84890289271
-
Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naive patients
-
Paolucci S, Fiorina L, Mariani B, et al. Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naive patients. Virol J 2013; 10:355.
-
(2013)
Virol J
, vol.10
, pp. 355
-
-
Paolucci, S.1
Fiorina, L.2
Mariani, B.3
-
5
-
-
84873041135
-
Hepatitis C virus variants with decreased sensitivity to direct-acting antivirals (DAAs) were rarely observed in DAA-naive patients prior to treatment
-
Bartels DJ, Sullivan JC, Zhang EZ, et al. Hepatitis C virus variants with decreased sensitivity to direct-acting antivirals (DAAs) were rarely observed in DAA-naive patients prior to treatment. J Virol 2013; 87:1544-1553.
-
(2013)
J Virol
, vol.87
, pp. 1544-1553
-
-
Bartels, D.J.1
Sullivan, J.C.2
Zhang, E.Z.3
-
6
-
-
77952035218
-
Chemical genetics strategy identiies an HCV NS5A inhibitor with a potent clinical effect
-
Gao M, Nettles RE, Belema M, et al. Chemical genetics strategy identiies an HCV NS5A inhibitor with a potent clinical effect. Nature 2010; 465:96-100.
-
(2010)
Nature
, vol.465
, pp. 96-100
-
-
Gao, M.1
Nettles, R.E.2
Belema, M.3
-
7
-
-
84921898327
-
Vitro and in vivo antiviral activity and resistance proile of ombitasvir, an inhibitor of hepatitis C virus NS5A
-
Krishnan P, Beyer J, Mistry N, et al. In vitro and in vivo antiviral activity and resistance proile of ombitasvir, an inhibitor of hepatitis C virus NS5A. Antimicrob Agents Chemother 2015; 59:979-987.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 979-987
-
-
Krishnan, P.1
Beyer, J.2
Mistry, N.3
-
8
-
-
84861546211
-
Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor, BMS-790052
-
Sun JH, O'Boyle Ii DR, Zhang Y, et al. Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor, BMS-790052. Hepatology 2012; 55:1692-1699.
-
(2012)
Hepatology
, vol.55
, pp. 1692-1699
-
-
Sun, J.H.1
O'Boyle Ii, D.R.2
Zhang, Y.3
-
9
-
-
84928175672
-
NS5A inhibitor resistance-associated polymorphisms in Brazilian treatmentnaive patients infected with genotype 1 hepatitis C virus
-
Peres-da-Silva A, de Almeida AJ, Lampe E. NS5A inhibitor resistance-associated polymorphisms in Brazilian treatmentnaive patients infected with genotype 1 hepatitis C virus. J Antimicrob Chemother 2015; 70:726-730.
-
(2015)
J Antimicrob Chemother
, vol.70
, pp. 726-730
-
-
Peres-Da-Silva, A.1
De Almeida, A.J.2
Lampe, E.3
-
10
-
-
84858415895
-
Prevalence of natural polymorphisms at the HCV NS5A gene associated with resistance to daclatasvir, an NS5A inhibitor
-
Plaza Z, Soriano V, Vispo E, et al. Prevalence of natural polymorphisms at the HCV NS5A gene associated with resistance to daclatasvir, an NS5A inhibitor. Antivir Ther 2012; 17:921-926.
-
(2012)
Antivir Ther
, vol.17
, pp. 921-926
-
-
Plaza, Z.1
Soriano, V.2
Vispo, E.3
-
11
-
-
84953359871
-
The clinical features of patients with a Y93H variant of hepatitis C virus detected by a PCR invader assay
-
Kan T, Hashimoto S, Kawabe N, et al. The clinical features of patients with a Y93H variant of hepatitis C virus detected by a PCR invader assay. J Gastroenterol 2016; 51:63-70.
-
(2016)
J Gastroenterol
, vol.51
, pp. 63-70
-
-
Kan, T.1
Hashimoto, S.2
Kawabe, N.3
-
12
-
-
84931269564
-
Prevalence of hepatitis C virus (HCV) variants resistant to NS5A inhibitors in naive patients infected with HCV genotype 1 in Tunisia
-
Aissa Larousse J, Trimoulet P, Recordon Pinson P, et al. Prevalence of hepatitis C virus (HCV) variants resistant to NS5A inhibitors in naive patients infected with HCV genotype 1 in Tunisia. Virol J 2015; 12:84.
-
(2015)
Virol J
, vol.12
, pp. 84
-
-
Aissa Larousse, J.1
Trimoulet, P.2
Recordon Pinson, P.3
-
13
-
-
84939174987
-
Naturally occurring, resistance-associated hepatitis C virus NS5A variants are linked to interleukin-28B genotype and are sensitive to interferon-based therapy
-
Itakura J, Kurosaki M, Takada H, et al. Naturally occurring, resistance-associated hepatitis C virus NS5A variants are linked to interleukin-28B genotype and are sensitive to interferon-based therapy. Hepatol Res 2015; 45:E115-E121.
-
(2015)
Hepatol Res
, vol.45
, pp. E115-E121
-
-
Itakura, J.1
Kurosaki, M.2
Takada, H.3
-
14
-
-
84940942461
-
Resistance analysis of baseline and treatment-emergent variants in the AVIATOR Study with paritaprevir/r, ombitasvir and dasabuvir in HCV genotype 1
-
Krishnan P, Tripathi R, Schnell G, et al. Resistance analysis of baseline and treatment-emergent variants in the AVIATOR Study with paritaprevir/r, ombitasvir and dasabuvir in HCV genotype 1. Antimicrob Agents Chemother 2015; 59:5445-5454.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 5445-5454
-
-
Krishnan, P.1
Tripathi, R.2
Schnell, G.3
-
15
-
-
84952636854
-
IFN lambda 4 genotypes and resistance-associated variants in HCV genotype 1 and 3 infected patients
-
Peiffer KH, Sommer L, Susser S, et al. IFN lambda 4 genotypes and resistance-associated variants in HCV genotype 1 and 3 infected patients. Hepatology 2016; 63:63-73.
-
(2016)
Hepatology
, vol.63
, pp. 63-73
-
-
Peiffer, K.H.1
Sommer, L.2
Susser, S.3
-
16
-
-
9144257569
-
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
-
Enomoto N, Sakuma I, Asahina Y, et al. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 1996; 334:77-81.
-
(1996)
N Engl J Med
, vol.334
, pp. 77-81
-
-
Enomoto, N.1
Sakuma, I.2
Asahina, Y.3
-
17
-
-
4344570256
-
Sustained virological response in hepatitis C virus type 1b infected patients is predicted by the number of mutations within the NS5AISDR: A meta-analysis focused on geographical differences
-
Pascu M, Martus P, Hohne M, et al. Sustained virological response in hepatitis C virus type 1b infected patients is predicted by the number of mutations within the NS5AISDR: a meta-analysis focused on geographical differences. Gut 2004; 53:1345-1351.
-
(2004)
Gut
, vol.53
, pp. 1345-1351
-
-
Pascu, M.1
Martus, P.2
Hohne, M.3
-
18
-
-
33747178354
-
Site-speciic mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication
-
Kohashi T, Maekawa S, Sakamoto N, et al. Site-speciic mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication. J Viral Hepat 2006; 13:582-590.
-
(2006)
J Viral Hepat
, vol.13
, pp. 582-590
-
-
Kohashi, T.1
Maekawa, S.2
Sakamoto, N.3
-
19
-
-
0036190918
-
Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate eficiently in cultured Huh7 cells
-
Ikeda M, Yi M, Li K, Lemon SM. Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate eficiently in cultured Huh7 cells. J Virol 2002; 76:2997-3006.
-
(2002)
J Virol
, vol.76
, pp. 2997-3006
-
-
Ikeda, M.1
Yi, M.2
Li, K.3
Lemon, S.M.4
-
20
-
-
34547591765
-
Contribution of insertions and deletions to the variability of hepatitis C virus populations
-
Torres-Puente M, Cuevas JM, Jimenez-Hernandez N, et al. Contribution of insertions and deletions to the variability of hepatitis C virus populations. J Gen Virol 2007; 88:2198-2203.
-
(2007)
J Gen Virol
, vol.88
, pp. 2198-2203
-
-
Torres-Puente, M.1
Cuevas, J.M.2
Jimenez-Hernandez, N.3
-
21
-
-
84896520682
-
Antiviral therapy of hepatitis C in 2014: Do we need resistance testing?
-
Schneider MD, Sarrazin C. Antiviral therapy of hepatitis C in 2014: do we need resistance testing? Antiviral Res 2014; 105:64-71.
-
(2014)
Antiviral Res
, vol.105
, pp. 64-71
-
-
Schneider, M.D.1
Sarrazin, C.2
-
22
-
-
84903701056
-
Update on hepatitis C virus resistance to directacting antiviral agents
-
Poveda E, Wyles DL, Mena A, Pedreira JD, Castro-Iglesias A, Cachay E. Update on hepatitis C virus resistance to directacting antiviral agents. Antiviral Res 2014; 108:181-191.
-
(2014)
Antiviral Res
, vol.108
, pp. 181-191
-
-
Poveda, E.1
Wyles, D.L.2
Mena, A.3
Pedreira, J.D.4
Castro-Iglesias, A.5
Cachay, E.6
-
23
-
-
84920945807
-
Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir
-
Donaldson EF, Harrington PR, O'Rear JJ, Naeger LK. Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir. Hepatology 2015; 61:56-65.
-
(2015)
Hepatology
, vol.61
, pp. 56-65
-
-
Donaldson, E.F.1
Harrington, P.R.2
O'Rear, J.J.3
Naeger, L.K.4
-
24
-
-
84894271490
-
In vivo emergence of a novel mutant L159F/L320F in the NS5B polymerase confers low-level resistance to the HCV polymerase inhibitors mericitabine and sofosbuvir
-
Tong X, Le Pogam S, Li L, et al. In vivo emergence of a novel mutant L159F/L320F in the NS5B polymerase confers low-level resistance to the HCV polymerase inhibitors mericitabine and sofosbuvir. J Infect Dis 2014; 209:668-675.
-
(2014)
J Infect Dis
, vol.209
, pp. 668-675
-
-
Tong, X.1
Le Pogam, S.2
Li, L.3
-
25
-
-
84964681423
-
Low frequency of drug-resistant virus did not affect the therapeutic eficacy in daclatasvir plus asunaprevir therapy in patients with chronic HCV genotype 1 infection
-
Kinugasa H, Ikeda F, Takaguchi K, et al. Low frequency of drug-resistant virus did not affect the therapeutic eficacy in daclatasvir plus asunaprevir therapy in patients with chronic HCV genotype 1 infection. Antivir Ther 2016; 21:37-44.
-
(2016)
Antivir Ther
, vol.21
, pp. 37-44
-
-
Kinugasa, H.1
Ikeda, F.2
Takaguchi, K.3
-
26
-
-
84880931245
-
Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir
-
Karino Y, Toyota J, Ikeda K, et al. Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir. J Hepatol 2013; 58:646-654.
-
(2013)
J Hepatol
, vol.58
, pp. 646-654
-
-
Karino, Y.1
Toyota, J.2
Ikeda, K.3
-
27
-
-
82455192239
-
Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: In vitro and in vivo correlations
-
Fridell RA, Wang C, Sun JH, et al. Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations. Hepatology 2011; 54:1924-1935.
-
(2011)
Hepatology
, vol.54
, pp. 1924-1935
-
-
Fridell, R.A.1
Wang, C.2
Sun, J.H.3
-
28
-
-
84876246624
-
Persistence of resistant variants in hepatitis C virus-infected patients treated with the NS5A replication complex inhibitor daclatasvir
-
Wang C, Sun JH, O'Boyle DR, II, et al. Persistence of resistant variants in hepatitis C virus-infected patients treated with the NS5A replication complex inhibitor daclatasvir. Antimicrob Agents Chemother 2013; 57:2054-2065.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 2054-2065
-
-
Wang, C.1
Sun, J.H.2
O'Boyle, D.R.I.I.3
-
29
-
-
77956116880
-
Resistance analysis of the hepatitis C virus NS5A inhibitor BMS-790052 in an in vitro replicon system
-
Fridell RA, Qiu D, Wang C, Valera L, Gao M. Resistance analysis of the hepatitis C virus NS5A inhibitor BMS-790052 in an in vitro replicon system. Antimicrob Agents Chemother 2010; 54:3641-3650.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3641-3650
-
-
Fridell, R.A.1
Qiu, D.2
Wang, C.3
Valera, L.4
Gao, M.5
-
30
-
-
84862684876
-
A Phase 1, randomized, placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C
-
Lawitz EJ, Gruener D, Hill JM, et al. A Phase 1, randomized, placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C. J Hepatol 2012; 57:24-31.
-
(2012)
J Hepatol
, vol.57
, pp. 24-31
-
-
Lawitz, E.J.1
Gruener, D.2
Hill, J.M.3
-
31
-
-
84905400652
-
In vitro activity and resistance proile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virus
-
Bilello JP, Lallos LB, McCarville JF, et al. In vitro activity and resistance proile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virus. Antimicrob Agents Chemother 2014; 58:4431-4442.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4431-4442
-
-
Bilello, J.P.1
Lallos, L.B.2
McCarville, J.F.3
-
32
-
-
84861109960
-
Genotype and subtype proiling of PSI-7977 as a nucleotide inhibitor of hepatitis C virus
-
Lam AM, Espiritu C, Bansal S, et al. Genotype and subtype proiling of PSI-7977 as a nucleotide inhibitor of hepatitis C virus. Antimicrob Agents Chemother 2012; 56:3359-3368.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 3359-3368
-
-
Lam, A.M.1
Espiritu, C.2
Bansal, S.3
-
33
-
-
84890869379
-
HCV direct-acting antiviral agents: The best interferon-free combinations
-
Schinazi R, Halfon P, Marcellin P, Asselah T. HCV direct-acting antiviral agents: the best interferon-free combinations. Liver Int 2014; 34 Suppl 1:69-78.
-
(2014)
Liver Int
, vol.34
, pp. 69-78
-
-
Schinazi, R.1
Halfon, P.2
Marcellin, P.3
Asselah, T.4
|