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Volumn 45, Issue 10, 2015, Pages E115-E121

Naturally occurring, resistance-associated hepatitis C virus NS5A variants are linked to interleukin-28B genotype and are sensitive to interferon-based therapy

Author keywords

Direct acting antivirals; Hepatitis C virus; Interferon based therapy; Interleukin 28B genotype; Resistance associated variants

Indexed keywords

INTERLEUKIN 28B; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5A; PEGINTERFERON; RIBAVIRIN;

EID: 84939174987     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/hepr.12474     Document Type: Article
Times cited : (36)

References (36)
  • 1
    • 84879606466 scopus 로고    scopus 로고
    • New horizons in hepatitis C antiviral therapy with direct-acting antivirals
    • Aghemo A, Francesco DR. New horizons in hepatitis C antiviral therapy with direct-acting antivirals. Hepatology 2013; 58: 428-438.
    • (2013) Hepatology , vol.58 , pp. 428-438
    • Aghemo, A.1    Francesco, D.R.2
  • 2
    • 84879290204 scopus 로고    scopus 로고
    • Direct-acting antivirals for the treatment of chronic hepatitis C: open issues and future perspectives
    • 704912
    • Chae HB, Park SM, Youn SJ. Direct-acting antivirals for the treatment of chronic hepatitis C: open issues and future perspectives. Scientific World J 2013; 2013: 704912. doi: 10.1155/2013/704912
    • (2013) Scientific World J , vol.2013
    • Chae, H.B.1    Park, S.M.2    Youn, S.J.3
  • 3
    • 84890939899 scopus 로고    scopus 로고
    • Antiviral treatment of hepatitis C virus infection and factors affecting efficacy
    • Zhu Y, Chen S. Antiviral treatment of hepatitis C virus infection and factors affecting efficacy. World J Gastroenterol 2013; 19: 8963-8973.
    • (2013) World J Gastroenterol , vol.19 , pp. 8963-8973
    • Zhu, Y.1    Chen, S.2
  • 4
    • 79958830099 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to protease inhibitors
    • Halfon P, Locarnini S. Hepatitis C virus resistance to protease inhibitors. J Hepatol 2011; 55: 192-206.
    • (2011) J Hepatol , vol.55 , pp. 192-206
    • Halfon, P.1    Locarnini, S.2
  • 5
    • 75149151884 scopus 로고    scopus 로고
    • Resistance to direct antiviral agents in patients with hepatitis C virus infection
    • Sarrazin C, Zeuzem S. Resistance to direct antiviral agents in patients with hepatitis C virus infection. Gastroenterology 2010; 138: 447-462.
    • (2010) Gastroenterology , vol.138 , pp. 447-462
    • Sarrazin, C.1    Zeuzem, S.2
  • 6
    • 84902548335 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to new specifically-targeted antiviral therapy: A public health perspective
    • Salvatierra K, Fareleski S, Forcada A, López-Labrador FX. Hepatitis C virus resistance to new specifically-targeted antiviral therapy: A public health perspective. World J Virol 2013; 2: 6-15.
    • (2013) World J Virol , vol.2 , pp. 6-15
    • Salvatierra, K.1    Fareleski, S.2    Forcada, A.3    López-Labrador, F.X.4
  • 7
    • 79955103901 scopus 로고    scopus 로고
    • Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus
    • Pawlotsky JM. Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus. Hepatology 2011; 53: 1742-1751.
    • (2011) Hepatology , vol.53 , pp. 1742-1751
    • Pawlotsky, J.M.1
  • 8
    • 58149388300 scopus 로고    scopus 로고
    • Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naive patients
    • Kuntzen T, Timm J, Berical A et al. Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naive patients. Hepatology 2008; 48: 1769-1778.
    • (2008) Hepatology , vol.48 , pp. 1769-1778
    • Kuntzen, T.1    Timm, J.2    Berical, A.3
  • 9
    • 84873041135 scopus 로고    scopus 로고
    • Hepatitis C virus variants with decreased sensitivity to direct-acting antivirals (DAAs) were rarely observed in DAA-naive patients prior to treatment
    • Bartels DJ, Sullivan JC, Zhang EZ et al. Hepatitis C virus variants with decreased sensitivity to direct-acting antivirals (DAAs) were rarely observed in DAA-naive patients prior to treatment. J Virol 2013; 87: 1544-1553.
    • (2013) J Virol , vol.87 , pp. 1544-1553
    • Bartels, D.J.1    Sullivan, J.C.2    Zhang, E.Z.3
  • 10
    • 79959995313 scopus 로고    scopus 로고
    • Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals
    • Robinson M, Tian Y, Delaney WE 4th, Greenstein AE. Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals. Proc Natl Acad Sci U S A 2011; 108: 10290-10295.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10290-10295
    • Robinson, M.1    Tian, Y.2    Delaney, W.E.3    Greenstein, A.E.4
  • 11
    • 9144257569 scopus 로고    scopus 로고
    • Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
    • Enomoto N, Sakuma I, Asahina Y et al. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 1996; 334: 77-81.
    • (1996) N Engl J Med , vol.334 , pp. 77-81
    • Enomoto, N.1    Sakuma, I.2    Asahina, Y.3
  • 12
    • 28944436403 scopus 로고    scopus 로고
    • Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load
    • Akuta N, Suzuki F, Sezaki H et al. Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load. J Med Virol 2006; 78: 83-90.
    • (2006) J Med Virol , vol.78 , pp. 83-90
    • Akuta, N.1    Suzuki, F.2    Sezaki, H.3
  • 13
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009; 41:1105-9.
    • (2009) Nat Genet , vol.41 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3
  • 14
    • 84860389491 scopus 로고    scopus 로고
    • IL28B single nucleotide polymorphisms in the treatment of hepatitis C
    • Lange CM, Zeuzem S. IL28B single nucleotide polymorphisms in the treatment of hepatitis C. J Hepatol 2011; 55: 692-701.
    • (2011) J Hepatol , vol.55 , pp. 692-701
    • Lange, C.M.1    Zeuzem, S.2
  • 15
    • 78649708165 scopus 로고    scopus 로고
    • IL28B and the control of hepatitis C virus infection
    • Balagopal A, Thomas DL, Thio CL. IL28B and the control of hepatitis C virus infection. Gastroenterology 2010; 139: 1865-1876.
    • (2010) Gastroenterology , vol.139 , pp. 1865-1876
    • Balagopal, A.1    Thomas, D.L.2    Thio, C.L.3
  • 16
    • 84905825880 scopus 로고    scopus 로고
    • Efficacy of daclatasvir in hepatitis C virus
    • Izumi N. Efficacy of daclatasvir in hepatitis C virus. Expert Rev Anti Infect Ther 2014; 12: 1025-31.
    • (2014) Expert Rev Anti Infect Ther , vol.12 , pp. 1025-1031
    • Izumi, N.1
  • 17
    • 84901217985 scopus 로고    scopus 로고
    • Simeprevir with peginterferon and ribavirin leads to high rates of SVR in patients with HCV genotype 1 who relapsed after previous therapy: a phase 3 trial
    • Forns X, Lawitz E, Zeuzem S et al. Simeprevir with peginterferon and ribavirin leads to high rates of SVR in patients with HCV genotype 1 who relapsed after previous therapy: a phase 3 trial. Gastroenterology 2014; 146:1669-1679.
    • (2014) Gastroenterology , vol.146 , pp. 1669-1679
    • Forns, X.1    Lawitz, E.2    Zeuzem, S.3
  • 18
    • 84945339322 scopus 로고    scopus 로고
    • the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America.
    • Recommendations for Testing, Managing, and Treating Hepatitis C 2014 by the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America. http://www.hcvguidelines.org
    • , vol.2014
  • 19
    • 84904991493 scopus 로고    scopus 로고
    • EASL Recommendations on Treatment of Hepatitis C
    • Accessed January 11, 2015.
    • Pawlotzky JM et al. EASL Recommendations on Treatment of Hepatitis C 2014. Available at: http://www.easl.eu/_newsroom/latest-news/easl-recommendations-on-treatment-of-hepatitis-c-2014. Accessed January 11, 2015.
    • (2014)
    • Pawlotzky, J.M.1
  • 21
    • 73149113353 scopus 로고    scopus 로고
    • Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients
    • Susser S, Welsch C, Wang Y et al. Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients. Hepatology 2009; 50: 1709-1718.
    • (2009) Hepatology , vol.50 , pp. 1709-1718
    • Susser, S.1    Welsch, C.2    Wang, Y.3
  • 22
    • 77951210464 scopus 로고    scopus 로고
    • In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435
    • Lenz O, Verbinnen T, Lin TI et al. In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435. Antimicrob Agents Chemother 2010; 54: 1878-1887.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 1878-1887
    • Lenz, O.1    Verbinnen, T.2    Lin, T.I.3
  • 23
    • 84864387126 scopus 로고    scopus 로고
    • MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants
    • Summa V, Ludmerer SW, McCauley JA et al. MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrob Agents Chemother 2012; 56: 4161-4167.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4161-4167
    • Summa, V.1    Ludmerer, S.W.2    McCauley, J.A.3
  • 24
    • 84880848789 scopus 로고    scopus 로고
    • Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: a population and clonal analysis
    • Barnard RJ, McHale CM, Newhard W et al. Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: a population and clonal analysis. Virology 2013; 443: 278-284.
    • (2013) Virology , vol.443 , pp. 278-284
    • Barnard, R.J.1    McHale, C.M.2    Newhard, W.3
  • 25
    • 84883219967 scopus 로고    scopus 로고
    • Resistance analysis of hepatitis C virus genotype 1 prior treatment null responders receiving daclatasvir and asunaprevir
    • McPhee F, Hernandez D, Yu F et al. Resistance analysis of hepatitis C virus genotype 1 prior treatment null responders receiving daclatasvir and asunaprevir. Hepatology 2013; 58: 902-911.
    • (2013) Hepatology , vol.58 , pp. 902-911
    • McPhee, F.1    Hernandez, D.2    Yu, F.3
  • 26
    • 82455192239 scopus 로고    scopus 로고
    • Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations
    • Fridell RA, Wang C, Sun JH et al. Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations. Hepatology 2011; 54: 1924-1935.
    • (2011) Hepatology , vol.54 , pp. 1924-1935
    • Fridell, R.A.1    Wang, C.2    Sun, J.H.3
  • 28
    • 84880931245 scopus 로고    scopus 로고
    • Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir
    • Karino Y, Toyota J, Ikeda K et al. Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir. J Hepatol 2013; 58: 646-654.
    • (2013) J Hepatol , vol.58 , pp. 646-654
    • Karino, Y.1    Toyota, J.2    Ikeda, K.3
  • 29
    • 84918525841 scopus 로고    scopus 로고
    • Deep Sequencing Analysis of Variants Resistant to the NS5A Inhibitor Daclatasvir in Patients with Genotype 1b Hepatitis C Virus Infection
    • Miura M, Maekawa S, Sato M et al. Deep Sequencing Analysis of Variants Resistant to the NS5A Inhibitor Daclatasvir in Patients with Genotype 1b Hepatitis C Virus Infection. Hepatol Res 2014; 44: E360-7.
    • (2014) Hepatol Res , vol.44 , pp. E360-E367
    • Miura, M.1    Maekawa, S.2    Sato, M.3
  • 30
    • 84906350125 scopus 로고    scopus 로고
    • Daclatasvir combined with peginterferon alfa-2a and ribavirin in Japanese patients infected with hepatitis C genotype 1
    • Izumi N, Yokosuka O, Kawada N et al. Daclatasvir combined with peginterferon alfa-2a and ribavirin in Japanese patients infected with hepatitis C genotype 1. Antivir Ther 2014; 19: 501-10.
    • (2014) Antivir Ther , vol.19 , pp. 501-510
    • Izumi, N.1    Yokosuka, O.2    Kawada, N.3
  • 31
    • 84900339263 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection
    • Afdhal N, Zeuzem S, Kwo P et al. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med 2014; 370:1889-98.
    • (2014) N Engl J Med , vol.370 , pp. 1889-1898
    • Afdhal, N.1    Zeuzem, S.2    Kwo, P.3
  • 32
    • 84898669547 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection
    • Afdhal N, Reddy KR, Nelson DR et al. Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection. N Engl J Med 2014; 370: 1483-1493.
    • (2014) N Engl J Med , vol.370 , pp. 1483-1493
    • Afdhal, N.1    Reddy, K.R.2    Nelson, D.R.3
  • 33
    • 84900326091 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for 8 or 12weeks for chronic HCV without cirrhosis
    • Kowdley KV, Gordon SC, Reddy KR et al. Ledipasvir and sofosbuvir for 8 or 12weeks for chronic HCV without cirrhosis. N Engl J Med 2014; 370: 1879-88.
    • (2014) N Engl J Med , vol.370 , pp. 1879-1888
    • Kowdley, K.V.1    Gordon, S.C.2    Reddy, K.R.3
  • 34
    • 84896520682 scopus 로고    scopus 로고
    • Antiviral therapy of hepatitis C in 2014: Do we need resistance testing?
    • Schneider MD, Sarrazin C. Antiviral therapy of hepatitis C in 2014: Do we need resistance testing? Antiviral Res 2014; 105: 64-71.
    • (2014) Antiviral Res , vol.105 , pp. 64-71
    • Schneider, M.D.1    Sarrazin, C.2
  • 35
    • 84882876118 scopus 로고    scopus 로고
    • Analysis of boceprevir resistance associated amino acid variants (RAVs) in two phase 3 boceprevir clinical studies
    • Barnard RJ, Howe JA, Ogert RA et al. Analysis of boceprevir resistance associated amino acid variants (RAVs) in two phase 3 boceprevir clinical studies. Virology 2013; 444: 329-336.
    • (2013) Virology , vol.444 , pp. 329-336
    • Barnard, R.J.1    Howe, J.A.2    Ogert, R.A.3
  • 36
    • 84879683134 scopus 로고    scopus 로고
    • Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials
    • Sullivan JC, De Meyer S, Bartels DJ et al. Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials. Clin Infect Dis 2013; 57: 221-229.
    • (2013) Clin Infect Dis , vol.57 , pp. 221-229
    • Sullivan, J.C.1    De Meyer, S.2    Bartels, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.