European multiple sclerosis risk variants in the south Asian population

Multiple Sclerosis

Volumn 22, Issue 12, 2016, Pages 1536-1540

  Pandit, Lekha ^a   Ban, Maria ^b   Beecham, Ashley Harris ^c   McCauley, Jacob L ^c   Sawcer, Stephen ^b   D'Cunha, Anitha ^a   Malli, Chaitra ^a   Malik, Omar ^c  

^a NITTE UNIVERSITY   (India)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

association; epidemiology; genetics; genomewide; Multiple sclerosis; south Asia

Indexed keywords

APRIL PROTEIN; B CELL ACTIVATING FACTOR;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ETHNIC DIFFERENCE; EUROPEAN; FEMALE; GENE; GENE FREQUENCY; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NEXT GENERATION SEQUENCING; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH ASIAN; TNFSF13 GENE; TNFSF13B GENE; ASIA; CAUCASIAN; DNA SEQUENCE; EUROPE; GENETICS; GENOTYPING TECHNIQUE; MIDDLE AGED;

ADULT; ASIA, WESTERN; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPING TECHNIQUES; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; SEQUENCE ANALYSIS, DNA;

EID: 84991407816     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458515624270     Document Type: Article

References (23)

1. Orton SM, Herrera BM, Yee IM, et al. Sex ratio of multiple sclerosis in Canada: A longitudinal study. Lancet Neurol 2006; 5: 932-936.
2. Wallin MT, Culpepper WJ, Coffman P, et al. The Gulf War era multiple sclerosis cohort: Age and incidence rates by race, sex and service. Brain 2012; 135: 1778-1785.
3. Pandit L, Kundapur R,. Prevalence and patterns of demyelinating central nervous system disorders in urban Mangalore, South India. Mult Scler 2014; 20: 1651-1653.
4. Sawcer S, Franklin RJ, Ban M,. Multiple sclerosis genetics. Lancet Neurol 2014; 13: 700-709.
5. International Multiple Sclerosis Genetics Consortium (IMSGC). A high-density screen for linkage in multiple sclerosis. Am J Hum Genet 2005; 77: 454-467.
6. International Multiple Sclerosis Genetics Consortium (IMSGC). A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol 2007; 61: 228-236.
7. International Multiple Sclerosis Genetics Consortium (IMSGC). Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 2007; 357: 851-862.
8. International Multiple Sclerosis Genetics Consortium (IMSGC) and Wellcome Trust Case Control Consortium (WTCCC2). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476: 214-219.
9. International Multiple Sclerosis Genetics Consortium (IMSGC). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet 2013; 45: 1353-1360.
10. Pandit L, Malli C, Singhal B, et al. HLA associations in South Asian multiple sclerosis. Mult Scler 2016; 22: 19-24.
11. Pandit L, Ban M, Sawcer S, et al. Evaluation of the established non-MHC multiple sclerosis loci in an Indian population. Mult Scler 2011; 17: 139-143.
12. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011; 69: 292-302.
13. Reich D, Thangaraj K, Patterson N, et al. Reconstructing Indian population history. Nature 2009; 461: 489-494.
14. International Multiple Sclerosis Genetics Consortium (IMSGC). Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol 2011; 70: 897-912.
15. Purcell S, Neale B, Todd-Brown K, et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575.
16. Warnes G, Duffy D, Man M, et al. Genetics design: functions for designing genetics studies (R package version 1.36.0, 1.36.0 ed.). 2010.
17. Sawcer S, Wason J,. Risk in complex genetics: 'All models are wrong but some are useful'. Ann Neurol 2012; 72: 502-509.
18. De Jager PL, Chibnik LB, Cui J, et al. Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score. Lancet Neurol 2009; 8: 1111-1119.
19. Isobe N, Madireddy L, Khankhanian P, et al. An ImmunoChip study of multiple sclerosis risk in African Americans. Brain 2015; 138: 1518-1530.
20. Daridon C, Youinou P, Pers JO,. BAFF, APRIL, TWE-PRIL: Who's who? Autoimmun Rev 2008; 7: 267-271.
21. Osman W, Okada Y, Kamatani Y, et al. Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. PLoS ONE 2012; 7: e32683.
22. Yang C, Jie W, Yanlong Y, et al. Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers. Immunogenetics 2012; 64: 747-753.
23. Cortes A, Brown MA,. Promise and pitfalls of the Immunochip. Arthritis Res Ther 2011; 13: 101.