HLA associations in South Asian multiple sclerosis

Multiple Sclerosis

Volumn 22, Issue 1, 2016, Pages 19-24

  Pandit, Lekha ^a   Malli, Chaithra ^a   Singhal, Bhim ^b   Wason, James ^c   Malik, Omar ^d   Sawcer, Stephen ^e   Ban, Maria ^e   D'Cunha, Anitha ^a   Mustafa, Sharik ^a  

^a NITTE UNIVERSITY   (India)

^b BOMBAY HOSPITAL   (India)

^c MRC BIOSTATISTICS UNIT   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

HLA; multiple sclerosis; South Asians

Indexed keywords

HLA A ANTIGEN; HLA ANTIGEN CLASS 2; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; HLA DQ ANTIGEN;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE REGISTRY; ETHNIC DIFFERENCE; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENOTYPING TECHNIQUE; HUMAN; INDIAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; POLYMERASE CHAIN REACTION; SOUTH ASIAN; DNA SEQUENCE; GENETIC ASSOCIATION STUDY; GENETICS; INDIA; MIDDLE AGED; REGISTER; EUROPEAN; GENETIC HETEROGENEITY; GENETIC RISK; GENETIC VARIATION; GENOTYPE; HLA SYSTEM; NUCLEOTIDE SEQUENCE;

ADULT; FEMALE; GENETIC ASSOCIATION STUDIES; HLA-DQ ALPHA-CHAINS; HLA-DQ BETA-CHAINS; HLA-DRB1 CHAINS; HUMANS; INDIA; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; POLYMERASE CHAIN REACTION; REGISTRIES; SEQUENCE ANALYSIS, DNA;

EID: 84951197399     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458515581439     Document Type: Article

References (28)

1. Syal P, Prabhakar S, Thussu A, et al. Clinical profile of multiple sclerosis in North-West India. Neurol India 1999; 47: 12-17.
2. Pandit L, Kundapur R,. Prevalence and patterns of Multiple sclerosis in India. Mult Scler 2014; 20: 1651-1653.
3. Kurtzke JF,. Epidemiology of multiple sclerosis. In: Koetssier JC, (ed.) Handbook of Clinical Neurology. Vol. 3 Demyelinating Diseases. Amsterdam: Elsevier Science; 1985, pp. 259-287.
4. The International Multiple Sclerosis Genetics Consortium (IMSGC). A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol 2007; 61: 228-236.
5. The International Multiple Sclerosis Genetics Consortium (IMSGC). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nat Genet 2011; 476: 214-219.
6. Naito S, Namerow N, Mickey MR, et al. Multiple sclerosis: association with HL-A3. Tiss Antigen 1972; 2: 1-4.
7. Jersild C, Hansen GS, Svejgaard A, et al. Histocompatibility determinants in multiple sclerosis, with special reference to clinical course. Lancet 1973; 302: 1221-1225.
8. Olerup O, Hillert J,. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tiss Antigen 1991; 38: 1-15.
9. Olerup O, Aldener A, Fogdel A,. HLA-DQB1 and DQA1 typing by PCR amplification with sequence specific primers (PCR-SSP) in 2 hours. Tiss Antigen 1993; 41: 119-134.
10. Marrosu MG, Murru MR, Costa G, et al. DRB1- DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population. Hum Mol Genet 1998; 7: 1235-1237.
11. Caballero A, Alvés-León S, Papais-Alvarenga R, et al. DQB1∗0602 confers genetic susceptibility to multiple sclerosis in Afro- Brazilians. Tiss Antigen 1999; 54: 524-526.
12. Oksenberg JR, Barcellos LF, Cree BA, et al. Mapping multiple sclerosis susceptibility to the HLA- DR locus in African Americans. Am J Hum Genet 2004; 74: 160-167.
13. Trikannad VS, Wadia NH, Krishnaswamy PR,. Multiple sclerosis and HLA-B12 in Parsi and non-Parsi Indians: A clarification. Tiss Antigen 1982; 19: 155-157.
14. Wadia NH, Trikannad VS, Krishnaswamy PR,. HLA antigens in multiple sclerosis amongst Indians. J Neurol Neurosurg Psychiatry 1982; 44: 849-851.
15. Kankonkar S, Jeyanthi B, Singhal BS, et al. Evidence for novel DRB1∗15 allele association among clinically definite multiple sclerosis patients from Mumbai, India. Hum Immunol 2003; 64: 478-482.
16. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria. Ann Neurol 2011; 69: 292-302.
17. Pandit L, Shetty R, Misri Z, et al. Optic neuritis: Experiences from a south Indian demyelinating disease registry. Neurol India 2012; 60: 470-475.
18. Reich D, Thangaraj K, Patterson N, et al. Reconstructing Indian population history. Nature 2009; 461: 489-494.
19. Olerup O, Zetterquist H,. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tiss Antigen 1992; 39: 225-235.
20. Cisneros E, Moraru M, de Pablo R, Vilches C,. A method for simple and accurate identification of the multiple sclerosis associated allele HLA-DRB1∗1501 in neuroscience research laboratories. J Neuroimmunol 2010; 225: 143-148.
21. Buuren S, Groothuis-Oudshoorn K,. MICE: Multivariate imputation by chained equations in R. J Stat Softw 2011; 45: 1-67.
22. Pandit L, Ban M, Sawcer S, et al. Evaluation of the established non-MHC multiple sclerosis loci in an Indian population. Mult Scler 2011 17: 139-143.
23. Shanmugalakshmi S, Balakrishnan K, Manoharan K, et al. HLA-DRB1∗ -DQB1∗ in Piramalai Kallars and Yadhavas, two Dravidian-speaking castes of Tamil Nadu, South India. Tiss Antigen 2003; 61: 451-464.
24. Patel JS, Patel MM, Koringa G, et al. Human leukocyte antigen alleles, genotypes and haplotypes frequencies in renal transplant donors and recipients from West Central India. Ind J Hum Genet 2013; 19: 219-232.
25. Silva MA, Pereira C, Bettencourt A, et al. The role of HLA-DRB1 alleles on susceptibility and outcome of a Portuguese multiple sclerosis population. J Neurol Sci 2007; 258: 69-74.
26. Pandit L, Malli C, D'Cunha A, et al. Association of Epstein-Barr virus infection with multiple sclerosis in India. J Neurol Sci 2013; 325: 86-89.
27. Pandit L, Ramagopalan SV, Malli C, et al. Association of vitamin D and multiple sclerosis in India. Mult Scler 2013; 12: 1592-1596.
28. Isobe N, Gourraud PA, Harbo HF, et al. Genetic risk variants in African Americans with multiple sclerosis. Neurology 2013; 81: 219-227.