Integrated approach to testing and assessment for predicting rodent genotoxic carcinogenicity

Journal of Applied Toxicology

Volumn 36, Issue 12, 2016, Pages 1536-1550

  Petkov, Petko I ^a   Schultz, Terry W ^b   Donner, E Maria ^c   Honma, Masamitsu ^d   Morita, Takeshi ^d   Hamada, Shuichi ^e   Wakata, Akihiro ^f   Mishima, Masayuki ^g   Maniwa, Jiro ^h   Todorov, Milen ^a   Kaloyanova, Elena ^a   Kotov, Stefan ^a   Mekenyan, Ovanes G ^a  

^a ASSEN ZLATAROV UNIVERSITY   (Bulgaria)

^b UNIVERSITY OF TENNESSEE   (United States)

^c DUPONT COMPANY   (United States)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^e LSI MEDIENCE CORPORATION   (Japan)

^f ASTELLAS PHARMA INC   (Japan)

^g CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^h ASTRAZENECA   (United Kingdom)

Author keywords

carcinogenicity; genotoxicity; IATA; OECD Toolbox; TIMES

Indexed keywords

ANDROGEN RECEPTOR; AROMATIC HYDROCARBON RECEPTOR; CARCINOGEN; ESTROGEN RECEPTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CELL PROLIFERATION; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; FEMALE; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MUTAGEN TESTING; MUTAGENICITY; NONHUMAN; ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RECEPTOR BINDING; SENSITIVITY AND SPECIFICITY; TISSUE METABOLISM;

EID: 84991233295     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3338     Document Type: Article

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