Identifying the structural requirements for chromosomal aberration by incorporating molecular flexibility and metabolic activation of chemicals

Chemical Research in Toxicology

Volumn 20, Issue 12, 2007, Pages 1927-1941

  Mekenyan, Ovanes ^a   Todorov, Milen ^a   Serafimova, Rossitsa ^a   Stoeva, Stoyanka ^a   Aptula, Aynur ^b   Finking, Robert ^c   Jacob, Elard ^c  

^a ASSEN ZLATAROV UNIVERSITY   (Bulgaria)

^b UNILEVER RESEARCH   (United Kingdom)

^c BASF SE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINE; AROMATIC NITRO COMPOUND; AZO COMPOUND; DNA TOPOISOMERASE; EPOXIDE; HISTONE; HYDRAZINE DERIVATIVE; NITROSOGUANIDINE; NITROSOUREA; NUCLEAR PROTEIN; PHENOL DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; QUINONE DERIVATIVE; RESORCINOL DERIVATIVE; SULFONAMIDE; SULFONIC ACID DERIVATIVE; URACIL; URETHAN DERIVATIVE; XANTHINE DERIVATIVE;

AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME ABERRATION; COMPARATIVE ANATOMY; CONTROLLED STUDY; DNA SYNTHESIS; GENOTOXICITY; IN VITRO STUDY; MUTAGENICITY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; DATABASES, FACTUAL; DNA, BACTERIAL; FIBROBLASTS; MODELS, BIOLOGICAL; MUTAGENICITY TESTS; MUTAGENS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); RATTUS;

EID: 38149020825     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx700249q     Document Type: Article

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