메뉴 건너뛰기




Volumn 240, Issue , 2016, Pages 127-134

Inhaled drug treatment for tuberculosis: Past progress and future prospects

Author keywords

Aerosols; Antibiotics; Inhaled therapy; Mycobacterium tuberculosis; Pulmonary drug delivery; Tuberculosis

Indexed keywords

AEROSOLS; ANTIBIOTICS; DRUG DOSAGE; VIRUSES;

EID: 84991072031     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.11.018     Document Type: Article
Times cited : (57)

References (98)
  • 1
    • 76549253387 scopus 로고
    • Aerosol streptomycin treatment of advanced pulmonary tuberculosis in children
    • [1] Miller, J.B., Abramson, H.A., Ratner, B., Aerosol streptomycin treatment of advanced pulmonary tuberculosis in children. Am. J. Dis. Child. 80:2 (1950), 207–237.
    • (1950) Am. J. Dis. Child. , vol.80 , Issue.2 , pp. 207-237
    • Miller, J.B.1    Abramson, H.A.2    Ratner, B.3
  • 2
    • 84877267006 scopus 로고    scopus 로고
    • Advances in the development of new tuberculosis drugs and treatment regimens
    • [2] Zumla, A., Nahid, P., Cole, S.T., Advances in the development of new tuberculosis drugs and treatment regimens. Nat. Rev. Drug Discov. 12:5 (2013), 388–404.
    • (2013) Nat. Rev. Drug Discov. , vol.12 , Issue.5 , pp. 388-404
    • Zumla, A.1    Nahid, P.2    Cole, S.T.3
  • 3
    • 79551498057 scopus 로고    scopus 로고
    • Inhaled drug therapy for treatment of tuberculosis
    • [3] Misra, A., et al. Inhaled drug therapy for treatment of tuberculosis. Tuberculosis (Edinb.) 91:1 (2011), 71–81.
    • (2011) Tuberculosis (Edinb.) , vol.91 , Issue.1 , pp. 71-81
    • Misra, A.1
  • 4
    • 85017385995 scopus 로고    scopus 로고
    • Aerosolized pentamidine for treatment and prophylaxis of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome
    • second edition Taylor & Francis
    • [4] Hickey, A.J., Montgomery, A.B., Aerosolized pentamidine for treatment and prophylaxis of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Pharmaceutical Inhalation Aerosol Technology, second edition, 2003, Taylor & Francis.
    • (2003) Pharmaceutical Inhalation Aerosol Technology
    • Hickey, A.J.1    Montgomery, A.B.2
  • 5
    • 84906784147 scopus 로고    scopus 로고
    • The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy
    • [5] Mortensen, N.P., Durham, P., Hickey, A.J., The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy. J. Microencapsul. 31:8 (2014), 785–795.
    • (2014) J. Microencapsul. , vol.31 , Issue.8 , pp. 785-795
    • Mortensen, N.P.1    Durham, P.2    Hickey, A.J.3
  • 6
    • 70350228508 scopus 로고    scopus 로고
    • Inhaled drug delivery for tuberculosis therapy
    • [6] Muttil, P., Wang, C., Hickey, A.J., Inhaled drug delivery for tuberculosis therapy. Pharm. Res. 26:11 (2009), 2401–2416.
    • (2009) Pharm. Res. , vol.26 , Issue.11 , pp. 2401-2416
    • Muttil, P.1    Wang, C.2    Hickey, A.J.3
  • 7
    • 17444377960 scopus 로고    scopus 로고
    • Antitubercular inhaled therapy: opportunities, progress and challenges
    • [7] Pandey, R., Khuller, G.K., Antitubercular inhaled therapy: opportunities, progress and challenges. J. Antimicrob. Chemother. 55:4 (2005), 430–435.
    • (2005) J. Antimicrob. Chemother. , vol.55 , Issue.4 , pp. 430-435
    • Pandey, R.1    Khuller, G.K.2
  • 8
    • 84886513932 scopus 로고    scopus 로고
    • Pharmaceutical aerosols for the treatment and prevention of tuberculosis
    • [8] Hanif, S.N.M., Garcia-Contreras, L., Pharmaceutical aerosols for the treatment and prevention of tuberculosis. Front. Cell. Infect. Microbiol., 2, 2012, 118.
    • (2012) Front. Cell. Infect. Microbiol. , vol.2 , pp. 118
    • Hanif, S.N.M.1    Garcia-Contreras, L.2
  • 9
    • 0038784717 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence
    • [9] Smith, I., Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clin. Microbiol. Rev. 16:3 (2003), 463–496.
    • (2003) Clin. Microbiol. Rev. , vol.16 , Issue.3 , pp. 463-496
    • Smith, I.1
  • 10
    • 84991058819 scopus 로고
    • Pathogenesis of pulmonary tuberculosis: an interplay of tissue-damaging and macrophage-activating immune responses—dual mechanisms that control bacillary multiplication. Tuberculosis: pathogenesis, protection, and control
    • (Washington, DC)
    • [10] Dannenberg, A.M. Jr., Rook, G.A., Pathogenesis of pulmonary tuberculosis: an interplay of tissue-damaging and macrophage-activating immune responses—dual mechanisms that control bacillary multiplication. Tuberculosis: pathogenesis, protection, and control. Am. Soc. Microbiol. 141 (1994), 1239–1245 (Washington, DC).
    • (1994) Am. Soc. Microbiol. , vol.141 , pp. 1239-1245
    • Dannenberg, A.M.1    Rook, G.A.2
  • 11
    • 48549100053 scopus 로고    scopus 로고
    • Human macrophage host defense against Mycobacterium tuberculosis
    • [11] Liu, P.T., Modlin, R.L., Human macrophage host defense against Mycobacterium tuberculosis. Curr. Opin. Immunol. 20:4 (2008), 371–376.
    • (2008) Curr. Opin. Immunol. , vol.20 , Issue.4 , pp. 371-376
    • Liu, P.T.1    Modlin, R.L.2
  • 12
    • 0036839223 scopus 로고    scopus 로고
    • Protection against tuberculosis: cytokines, T cells, and macrophages
    • [12] Kaufmann, S., Protection against tuberculosis: cytokines, T cells, and macrophages. Ann. Rheum. Dis. 61:Suppl. 2 (2002), ii54–ii58.
    • (2002) Ann. Rheum. Dis. , vol.61 , pp. ii54-ii58
    • Kaufmann, S.1
  • 13
    • 84890391146 scopus 로고    scopus 로고
    • Pulmonary drug delivery: an historical overview
    • H.D.C. Smyth A.J. Hickey Springer New York
    • [13] Sanders, M., Pulmonary drug delivery: an historical overview. Smyth, H.D.C., Hickey, A.J., (eds.) Controlled Pulmonary Drug Delivery, 2011, Springer, New York.
    • (2011) Controlled Pulmonary Drug Delivery
    • Sanders, M.1
  • 14
    • 79959984752 scopus 로고    scopus 로고
    • Herbal Simples Approved for Modern Uses of Cure
    • Echo Library
    • [14] Fernie, W.T., Herbal Simples Approved for Modern Uses of Cure. 2008, Echo Library.
    • (2008)
    • Fernie, W.T.1
  • 15
    • 0035008416 scopus 로고    scopus 로고
    • A history of nebulization
    • [15] Dessanges, J.F., A history of nebulization. J. Aerosol Med. 14:1 (2001), 65–71.
    • (2001) J. Aerosol Med. , vol.14 , Issue.1 , pp. 65-71
    • Dessanges, J.F.1
  • 16
    • 0011489418 scopus 로고    scopus 로고
    • Dispersion and characterization of pharmaceutical dry powder aerosols
    • [16] Dunbar, C.A., Hickey, A.J., Holzner, P., Dispersion and characterization of pharmaceutical dry powder aerosols. Kona Powder Part. J. 16 (1998), 7–45.
    • (1998) Kona Powder Part. J. , vol.16 , pp. 7-45
    • Dunbar, C.A.1    Hickey, A.J.2    Holzner, P.3
  • 17
    • 33644617924 scopus 로고    scopus 로고
    • Dry powder inhaler formulation
    • [17] Telko, M.J., Hickey, A.J., Dry powder inhaler formulation. Respir. Care 50:9 (2005), 1209–1227.
    • (2005) Respir. Care , vol.50 , Issue.9 , pp. 1209-1227
    • Telko, M.J.1    Hickey, A.J.2
  • 19
    • 84857639619 scopus 로고    scopus 로고
    • Therapeutic aerosol bioengineering of targeted, inhalable microparticle formulations to treat Mycobacterium tuberculosis (MTb)
    • [19] Lawlor, C., et al. Therapeutic aerosol bioengineering of targeted, inhalable microparticle formulations to treat Mycobacterium tuberculosis (MTb). J. Mater. Sci. Mater. Med. 23:1 (2012), 89–98.
    • (2012) J. Mater. Sci. Mater. Med. , vol.23 , Issue.1 , pp. 89-98
    • Lawlor, C.1
  • 20
    • 84864645030 scopus 로고    scopus 로고
    • Preparation and characterisation of novel spray-dried nano-structured para-aminosalicylic acid particulates for pulmonary delivery: impact of ammonium carbonate on morphology, chemical composition and solid state
    • [20] Gad, S., et al. Preparation and characterisation of novel spray-dried nano-structured para-aminosalicylic acid particulates for pulmonary delivery: impact of ammonium carbonate on morphology, chemical composition and solid state. J. Pharm. Pharmacol. 64:9 (2012), 1264–1274.
    • (2012) J. Pharm. Pharmacol. , vol.64 , Issue.9 , pp. 1264-1274
    • Gad, S.1
  • 21
    • 0347418154 scopus 로고    scopus 로고
    • Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages
    • [21] Vyas, S.P., et al. Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages. Int. J. Pharm. 269:1 (2004), 37–49.
    • (2004) Int. J. Pharm. , vol.269 , Issue.1 , pp. 37-49
    • Vyas, S.P.1
  • 22
    • 23144445286 scopus 로고    scopus 로고
    • Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug
    • E28
    • [22] Sethuraman, V.V., Hickey, A.J., Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug. AAPS PharmSciTech, 3(4), 2002, E28.
    • (2002) AAPS PharmSciTech , vol.3 , Issue.4
    • Sethuraman, V.V.1    Hickey, A.J.2
  • 23
    • 84906540333 scopus 로고    scopus 로고
    • Microparticles of rifampicin: comparison of pulmonary route with oral route for drug uptake by alveolar macrophages, phagocytosis activity and toxicity study in albino rats
    • [23] Parikh, R., Patel, L., Dalwadi, S., Microparticles of rifampicin: comparison of pulmonary route with oral route for drug uptake by alveolar macrophages, phagocytosis activity and toxicity study in albino rats. Drug Deliv. 21:6 (2014), 406–411.
    • (2014) Drug Deliv. , vol.21 , Issue.6 , pp. 406-411
    • Parikh, R.1    Patel, L.2    Dalwadi, S.3
  • 24
    • 84881578909 scopus 로고    scopus 로고
    • Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage
    • [24] Vadakkan, M.V., et al. Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. Int. J. Nanomedicine 8 (2013), 2871–2885.
    • (2013) Int. J. Nanomedicine , vol.8 , pp. 2871-2885
    • Vadakkan, M.V.1
  • 25
    • 0033795452 scopus 로고    scopus 로고
    • Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: manufacture and characterization
    • [25] O'Hara, P., Hickey, A.J., Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: manufacture and characterization. Pharm. Res. 17:8 (2000), 955–961.
    • (2000) Pharm. Res. , vol.17 , Issue.8 , pp. 955-961
    • O'Hara, P.1    Hickey, A.J.2
  • 26
    • 77349119814 scopus 로고    scopus 로고
    • Delivery of rifampicin-PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis
    • [26] Hirota, K., et al. Delivery of rifampicin-PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis. J. Control. Release 142:3 (2010), 339–346.
    • (2010) J. Control. Release , vol.142 , Issue.3 , pp. 339-346
    • Hirota, K.1
  • 27
    • 84873246196 scopus 로고    scopus 로고
    • Distribution and deposition of respirable PLGA microspheres in lung alveoli
    • [27] Hirota, K., et al. Distribution and deposition of respirable PLGA microspheres in lung alveoli. Colloids Surf. B: Biointerfaces 105 (2013), 92–97.
    • (2013) Colloids Surf. B: Biointerfaces , vol.105 , pp. 92-97
    • Hirota, K.1
  • 28
    • 0034848118 scopus 로고    scopus 로고
    • Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: screening in an infectious disease model
    • [28] Suarez, S., et al. Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: screening in an infectious disease model. Pharm. Res. 18:9 (2001), 1315–1319.
    • (2001) Pharm. Res. , vol.18 , Issue.9 , pp. 1315-1319
    • Suarez, S.1
  • 29
    • 34547627972 scopus 로고    scopus 로고
    • Evaluation of dosing regimen of respirable rifampicin biodegradable microspheres in the treatment of tuberculosis in the guinea pig
    • [29] Garcia-Contreras, L., et al. Evaluation of dosing regimen of respirable rifampicin biodegradable microspheres in the treatment of tuberculosis in the guinea pig. J. Antimicrob. Chemother. 58:5 (2006), 980–986.
    • (2006) J. Antimicrob. Chemother. , vol.58 , Issue.5 , pp. 980-986
    • Garcia-Contreras, L.1
  • 30
    • 61649118970 scopus 로고    scopus 로고
    • One-step preparation of rifampicin/poly(lactic-co-glycolic acid) nanoparticle-containing mannitol microspheres using a four-fluid nozzle spray drier for inhalation therapy of tuberculosis
    • [30] Ohashi, K., et al. One-step preparation of rifampicin/poly(lactic-co-glycolic acid) nanoparticle-containing mannitol microspheres using a four-fluid nozzle spray drier for inhalation therapy of tuberculosis. J. Control. Release 135:1 (2009), 19–24.
    • (2009) J. Control. Release , vol.135 , Issue.1 , pp. 19-24
    • Ohashi, K.1
  • 31
    • 84892169113 scopus 로고    scopus 로고
    • Inhaled solid lipid microparticles to target alveolar macrophages for tuberculosis
    • [31] Maretti, E., et al. Inhaled solid lipid microparticles to target alveolar macrophages for tuberculosis. Int. J. Pharm. 462:1–2 (2014), 74–82.
    • (2014) Int. J. Pharm. , vol.462 , Issue.1-2 , pp. 74-82
    • Maretti, E.1
  • 32
    • 84862576659 scopus 로고    scopus 로고
    • Mouse model for efficacy testing of antituberculosis agents via intrapulmonary delivery
    • [32] Gonzalez-Juarrero, M., et al. Mouse model for efficacy testing of antituberculosis agents via intrapulmonary delivery. Antimicrob. Agents Chemother. 56:7 (2012), 3957–3959.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , Issue.7 , pp. 3957-3959
    • Gonzalez-Juarrero, M.1
  • 33
    • 84901489961 scopus 로고    scopus 로고
    • Inhaled microparticles of antitubercular antibiotic for in vitro and in vivo alveolar macrophage targeting and activation of phagocytosis
    • (Tokyo)
    • [33] Parikh, R., et al. Inhaled microparticles of antitubercular antibiotic for in vitro and in vivo alveolar macrophage targeting and activation of phagocytosis. J Antibiot. 67:5 (2014), 387–394 (Tokyo).
    • (2014) J Antibiot. , vol.67 , Issue.5 , pp. 387-394
    • Parikh, R.1
  • 34
    • 79960774579 scopus 로고    scopus 로고
    • Isoniazid proliposome powders for inhalation-preparation, characterization and cell culture studies
    • [34] Rojanarat, W., et al. Isoniazid proliposome powders for inhalation-preparation, characterization and cell culture studies. Int. J. Mol. Sci. 12:7 (2011), 4414–4434.
    • (2011) Int. J. Mol. Sci. , vol.12 , Issue.7 , pp. 4414-4434
    • Rojanarat, W.1
  • 35
    • 0036285999 scopus 로고    scopus 로고
    • Hydrophobic ion pairing of isoniazid using a prodrug approach
    • [35] Zhou, H., et al. Hydrophobic ion pairing of isoniazid using a prodrug approach. J. Pharm. Sci. 91:6 (2002), 1502–1511.
    • (2002) J. Pharm. Sci. , vol.91 , Issue.6 , pp. 1502-1511
    • Zhou, H.1
  • 36
    • 0033255665 scopus 로고    scopus 로고
    • Effects of INH (isoniazid) inhalation in patients with endobronchial tuberculosis (EBTB)
    • [36] Yokota, S., Miki, K., Effects of INH (isoniazid) inhalation in patients with endobronchial tuberculosis (EBTB). Kekkaku 74:12 (1999), 873–877.
    • (1999) Kekkaku , vol.74 , Issue.12 , pp. 873-877
    • Yokota, S.1    Miki, K.2
  • 37
    • 84884168091 scopus 로고    scopus 로고
    • Formulation of pyrazinamide-loaded large porous particles for the pulmonary route: avoiding crystal growth using excipients
    • [37] Pham, D.D., et al. Formulation of pyrazinamide-loaded large porous particles for the pulmonary route: avoiding crystal growth using excipients. Int. J. Pharm. 454:2 (2013), 668–677.
    • (2013) Int. J. Pharm. , vol.454 , Issue.2 , pp. 668-677
    • Pham, D.D.1
  • 38
    • 84938389586 scopus 로고    scopus 로고
    • Spray dried aerosol particles of salts for tuberculosis therapy
    • [38] Durham, P.G., et al. Spray dried aerosol particles of salts for tuberculosis therapy. Mol. Pharm. 12:8 (2015), 2574–2581.
    • (2015) Mol. Pharm. , vol.12 , Issue.8 , pp. 2574-2581
    • Durham, P.G.1
  • 39
    • 84867567038 scopus 로고    scopus 로고
    • Inhaled pyrazinamide proliposome for targeting alveolar macrophages
    • [39] Rojanarat, W., et al. Inhaled pyrazinamide proliposome for targeting alveolar macrophages. Drug Deliv. 19:7 (2012), 334–345.
    • (2012) Drug Deliv. , vol.19 , Issue.7 , pp. 334-345
    • Rojanarat, W.1
  • 40
    • 0035134275 scopus 로고    scopus 로고
    • Adjunctive salvage therapy with inhaled aminoglycosides for patients with persistent smear-positive pulmonary tuberculosis
    • [40] Sacks, L.V., et al. Adjunctive salvage therapy with inhaled aminoglycosides for patients with persistent smear-positive pulmonary tuberculosis. Clin. Infect. Dis. 32:1 (2001), 44–49.
    • (2001) Clin. Infect. Dis. , vol.32 , Issue.1 , pp. 44-49
    • Sacks, L.V.1
  • 41
    • 0034101659 scopus 로고    scopus 로고
    • Aerosolized interferon-alpha treatment in patients with multi-drug-resistant pulmonary tuberculosis
    • [41] Giosue, S., et al. Aerosolized interferon-alpha treatment in patients with multi-drug-resistant pulmonary tuberculosis. Eur. Cytokine Netw. 11:1 (2000), 99–104.
    • (2000) Eur. Cytokine Netw. , vol.11 , Issue.1 , pp. 99-104
    • Giosue, S.1
  • 42
    • 10744232820 scopus 로고    scopus 로고
    • Aerosolized gamma interferon (IFN-gamma) induces expression of the genes encoding the IFN-gamma-inducible 10-kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis
    • [42] Raju, B., et al. Aerosolized gamma interferon (IFN-gamma) induces expression of the genes encoding the IFN-gamma-inducible 10-kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis. Infect. Immun. 72:3 (2004), 1275–1283.
    • (2004) Infect. Immun. , vol.72 , Issue.3 , pp. 1275-1283
    • Raju, B.1
  • 43
    • 0037379391 scopus 로고    scopus 로고
    • Recombinant gamma interferon stimulates signal transduction and gene expression in alveolar macrophages in vitro and in tuberculosis patients
    • [43] Condos, R., et al. Recombinant gamma interferon stimulates signal transduction and gene expression in alveolar macrophages in vitro and in tuberculosis patients. Infect. Immun. 71:4 (2003), 2058–2064.
    • (2003) Infect. Immun. , vol.71 , Issue.4 , pp. 2058-2064
    • Condos, R.1
  • 44
    • 45349092396 scopus 로고    scopus 로고
    • A new protocol for multiple inhalation of IFN-gamma successfully treats MDR-TB: a case study
    • [44] Grahmann, P.R., Braun, R.K., A new protocol for multiple inhalation of IFN-gamma successfully treats MDR-TB: a case study. Int. J. Tuberc. Lung Dis. 12:6 (2008), 636–644.
    • (2008) Int. J. Tuberc. Lung Dis. , vol.12 , Issue.6 , pp. 636-644
    • Grahmann, P.R.1    Braun, R.K.2
  • 45
    • 2942740857 scopus 로고    scopus 로고
    • Regional deposition of aerosolized interferon-gamma in pulmonary tuberculosis
    • [45] Condos, R., et al. Regional deposition of aerosolized interferon-gamma in pulmonary tuberculosis. Chest 125:6 (2004), 2146–2155.
    • (2004) Chest , vol.125 , Issue.6 , pp. 2146-2155
    • Condos, R.1
  • 46
    • 2342531580 scopus 로고    scopus 로고
    • Six-month therapy with aerosolized interferon-gamma for refractory multidrug-resistant pulmonary tuberculosis
    • [46] Koh, W.J., et al. Six-month therapy with aerosolized interferon-gamma for refractory multidrug-resistant pulmonary tuberculosis. J. Korean Med. Sci. 19:2 (2004), 167–171.
    • (2004) J. Korean Med. Sci. , vol.19 , Issue.2 , pp. 167-171
    • Koh, W.J.1
  • 47
    • 0034242395 scopus 로고    scopus 로고
    • A case of multidrug-resistant pulmonary tuberculosis
    • [47] Tsurutani, J., et al. A case of multidrug-resistant pulmonary tuberculosis. Nihon Kokyuki Gakkai Zasshi 38:8 (2000), 594–598.
    • (2000) Nihon Kokyuki Gakkai Zasshi , vol.38 , Issue.8 , pp. 594-598
    • Tsurutani, J.1
  • 48
    • 0035888002 scopus 로고    scopus 로고
    • Clinical and microbiological efficacy of adjunctive salvage therapy with inhaled aminoglycosides in a patient with refractory cavitary pulmonary tuberculosis
    • [48] Parola, P., Brouqui, P., Clinical and microbiological efficacy of adjunctive salvage therapy with inhaled aminoglycosides in a patient with refractory cavitary pulmonary tuberculosis. Clin. Infect. Dis., 33(8), 2001, 1439.
    • (2001) Clin. Infect. Dis. , vol.33 , Issue.8 , pp. 1439
    • Parola, P.1    Brouqui, P.2
  • 49
    • 0034900387 scopus 로고    scopus 로고
    • Treatment of ulcerative endobronchial tuberculosis and bronchial stenosis with aerosolized streptomycin and steroids
    • [49] Rikimaru, T., et al. Treatment of ulcerative endobronchial tuberculosis and bronchial stenosis with aerosolized streptomycin and steroids. Int. J. Tuberc. Lung Dis. 5:8 (2001), 769–774.
    • (2001) Int. J. Tuberc. Lung Dis. , vol.5 , Issue.8 , pp. 769-774
    • Rikimaru, T.1
  • 50
    • 84899787031 scopus 로고    scopus 로고
    • Capreomycin inhalable powders prepared with an innovative spray-drying technique
    • [50] Schoubben, A., et al. Capreomycin inhalable powders prepared with an innovative spray-drying technique. Int. J. Pharm. 469:1 (2014), 132–139.
    • (2014) Int. J. Pharm. , vol.469 , Issue.1 , pp. 132-139
    • Schoubben, A.1
  • 51
    • 84875209682 scopus 로고    scopus 로고
    • Capreomycin supergenerics for pulmonary tuberculosis treatment: preparation, in vitro, and in vivo characterization
    • [51] Schoubben, A., et al. Capreomycin supergenerics for pulmonary tuberculosis treatment: preparation, in vitro, and in vivo characterization. Eur. J. Pharm. Biopharm. 83:3 (2013), 388–395.
    • (2013) Eur. J. Pharm. Biopharm. , vol.83 , Issue.3 , pp. 388-395
    • Schoubben, A.1
  • 52
    • 84860109542 scopus 로고    scopus 로고
    • Pharmacokinetics of sequential doses of capreomycin powder for inhalation in guinea pigs
    • [52] Garcia-Contreras, L., et al. Pharmacokinetics of sequential doses of capreomycin powder for inhalation in guinea pigs. Antimicrob. Agents Chemother. 56:5 (2012), 2612–2618.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , Issue.5 , pp. 2612-2618
    • Garcia-Contreras, L.1
  • 53
    • 34547642167 scopus 로고    scopus 로고
    • Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model
    • [53] Garcia-Contreras, L., et al. Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model. Antimicrob. Agents Chemother. 51:8 (2007), 2830–2836.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , Issue.8 , pp. 2830-2836
    • Garcia-Contreras, L.1
  • 54
    • 73749084878 scopus 로고    scopus 로고
    • Simple and scalable method for peptide inhalable powder production
    • [54] Schoubben, A., et al. Simple and scalable method for peptide inhalable powder production. Eur. J. Pharm. Sci. 39:1–3 (2010), 53–58.
    • (2010) Eur. J. Pharm. Sci. , vol.39 , Issue.1-3 , pp. 53-58
    • Schoubben, A.1
  • 55
    • 84872859798 scopus 로고    scopus 로고
    • Inhaled microparticles containing clofazimine are efficacious in treatment of experimental tuberculosis in mice
    • [55] Verma, R.K., et al. Inhaled microparticles containing clofazimine are efficacious in treatment of experimental tuberculosis in mice. Antimicrob. Agents Chemother. 57:2 (2013), 1050–1052.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , Issue.2 , pp. 1050-1052
    • Verma, R.K.1
  • 56
    • 84856077790 scopus 로고    scopus 로고
    • Aerosolized gentamicin reduces the burden of tuberculosis in a murine model
    • [56] Roy, C.J., et al. Aerosolized gentamicin reduces the burden of tuberculosis in a murine model. Antimicrob. Agents Chemother. 56:2 (2012), 883–886.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , Issue.2 , pp. 883-886
    • Roy, C.J.1
  • 57
    • 77954817188 scopus 로고    scopus 로고
    • Isoxyl aerosols for tuberculosis treatment: preparation and characterization of particles
    • [57] Wang, C., Hickey, A.J., Isoxyl aerosols for tuberculosis treatment: preparation and characterization of particles. AAPS PharmSciTech 11:2 (2010), 538–549.
    • (2010) AAPS PharmSciTech , vol.11 , Issue.2 , pp. 538-549
    • Wang, C.1    Hickey, A.J.2
  • 58
    • 11144298628 scopus 로고    scopus 로고
    • Kanamycin incorporation in lipid vesicles prepared by ethanol injection designed for tuberculosis treatment
    • [58] Justo, O.R., Moraes, A.M., Kanamycin incorporation in lipid vesicles prepared by ethanol injection designed for tuberculosis treatment. J. Pharm. Pharmacol. 57:1 (2005), 23–30.
    • (2005) J. Pharm. Pharmacol. , vol.57 , Issue.1 , pp. 23-30
    • Justo, O.R.1    Moraes, A.M.2
  • 59
    • 84872791453 scopus 로고    scopus 로고
    • Chitosan microspheres as an alveolar macrophage delivery system of ofloxacin via pulmonary inhalation
    • [59] Park, J.H., et al. Chitosan microspheres as an alveolar macrophage delivery system of ofloxacin via pulmonary inhalation. Int. J. Pharm. 441:1–2 (2013), 562–569.
    • (2013) Int. J. Pharm. , vol.441 , Issue.1-2 , pp. 562-569
    • Park, J.H.1
  • 60
    • 46549090057 scopus 로고    scopus 로고
    • Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis
    • [60] Hwang, S.M., et al. Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis. J. Control. Release 129:2 (2008), 100–106.
    • (2008) J. Control. Release , vol.129 , Issue.2 , pp. 100-106
    • Hwang, S.M.1
  • 61
    • 84872294618 scopus 로고    scopus 로고
    • Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin-palladium complex
    • [61] Palazzo, F., et al. Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin-palladium complex. Int. J. Pharm. 440:2 (2013), 273–282.
    • (2013) Int. J. Pharm. , vol.440 , Issue.2 , pp. 273-282
    • Palazzo, F.1
  • 62
    • 65649147964 scopus 로고    scopus 로고
    • Dry powder nitroimidazopyran antibiotic PA-824 aerosol for inhalation
    • [62] Sung, J.C., et al. Dry powder nitroimidazopyran antibiotic PA-824 aerosol for inhalation. Antimicrob. Agents Chemother. 53:4 (2009), 1338–1343.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , Issue.4 , pp. 1338-1343
    • Sung, J.C.1
  • 63
    • 77950101234 scopus 로고    scopus 로고
    • Dry powder PA-824 aerosols for treatment of tuberculosis in guinea pigs
    • [63] Garcia-Contreras, L., et al. Dry powder PA-824 aerosols for treatment of tuberculosis in guinea pigs. Antimicrob. Agents Chemother. 54:4 (2010), 1436–1442.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , Issue.4 , pp. 1436-1442
    • Garcia-Contreras, L.1
  • 64
    • 10744225450 scopus 로고    scopus 로고
    • Direct lung delivery of para-aminosalicylic acid by aerosol particles
    • [64] Tsapis, N., et al. Direct lung delivery of para-aminosalicylic acid by aerosol particles. Tuberculosis (Edinb.) 83:6 (2003), 379–385.
    • (2003) Tuberculosis (Edinb.) , vol.83 , Issue.6 , pp. 379-385
    • Tsapis, N.1
  • 65
    • 84897977285 scopus 로고    scopus 로고
    • Inhalable particles containing rapamycin for induction of autophagy in macrophages infected with Mycobacterium tuberculosis
    • [65] Gupta, A., et al. Inhalable particles containing rapamycin for induction of autophagy in macrophages infected with Mycobacterium tuberculosis. Mol. Pharm. 11:4 (2014), 1201–1207.
    • (2014) Mol. Pharm. , vol.11 , Issue.4 , pp. 1201-1207
    • Gupta, A.1
  • 66
    • 84898015823 scopus 로고    scopus 로고
    • A novel inhalable form of rifapentine
    • [66] Chan, J.G., et al. A novel inhalable form of rifapentine. J. Pharm. Sci. 103:5 (2014), 1411–1421.
    • (2014) J. Pharm. Sci. , vol.103 , Issue.5 , pp. 1411-1421
    • Chan, J.G.1
  • 67
    • 84929076528 scopus 로고    scopus 로고
    • Rifapentine-proliposomes for inhalation: in vitro and in vivo toxicity
    • [67] Patil-Gadhe, A.A., et al. Rifapentine-proliposomes for inhalation: in vitro and in vivo toxicity. Toxicol. Int. 21:3 (2014), 275–282.
    • (2014) Toxicol. Int. , vol.21 , Issue.3 , pp. 275-282
    • Patil-Gadhe, A.A.1
  • 68
    • 67651172938 scopus 로고    scopus 로고
    • Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis
    • [68] Rosas-Taraco, A.G., et al. Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis. Am. J. Respir. Cell Mol. Biol. 41:2 (2009), 136–145.
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.41 , Issue.2 , pp. 136-145
    • Rosas-Taraco, A.G.1
  • 69
    • 65549109778 scopus 로고    scopus 로고
    • Evaluation of antitubercular drug-loaded surfactants as inhalable drug-delivery systems for pulmonary tuberculosis
    • [69] Chimote, G., Banerjee, R., Evaluation of antitubercular drug-loaded surfactants as inhalable drug-delivery systems for pulmonary tuberculosis. J. Biomed. Mater. Res. A 89:2 (2009), 281–292.
    • (2009) J. Biomed. Mater. Res. A , vol.89 , Issue.2 , pp. 281-292
    • Chimote, G.1    Banerjee, R.2
  • 70
    • 84873703779 scopus 로고    scopus 로고
    • A novel dry powder inhalable formulation incorporating three first-line anti-tubercular antibiotics
    • [70] Chan, J.G., et al. A novel dry powder inhalable formulation incorporating three first-line anti-tubercular antibiotics. Eur. J. Pharm. Biopharm. 83:2 (2013), 285–292.
    • (2013) Eur. J. Pharm. Biopharm. , vol.83 , Issue.2 , pp. 285-292
    • Chan, J.G.1
  • 71
    • 25144447412 scopus 로고    scopus 로고
    • Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis
    • [71] Ahmad, Z., Sharma, S., Khuller, G.K., Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis. Int. J. Antimicrob. Agents 26:4 (2005), 298–303.
    • (2005) Int. J. Antimicrob. Agents , vol.26 , Issue.4 , pp. 298-303
    • Ahmad, Z.1    Sharma, S.2    Khuller, G.K.3
  • 72
    • 6344277290 scopus 로고    scopus 로고
    • Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis
    • [72] Sharma, A., Sharma, S., Khuller, G.K., Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis. J. Antimicrob. Chemother. 54:4 (2004), 761–766.
    • (2004) J. Antimicrob. Chemother. , vol.54 , Issue.4 , pp. 761-766
    • Sharma, A.1    Sharma, S.2    Khuller, G.K.3
  • 73
    • 20444385102 scopus 로고    scopus 로고
    • Solid lipid particle-based inhalable sustained drug delivery system against experimental tuberculosis
    • [73] Pandey, R., Khuller, G.K., Solid lipid particle-based inhalable sustained drug delivery system against experimental tuberculosis. Tuberculosis (Edinb.) 85:4 (2005), 227–234.
    • (2005) Tuberculosis (Edinb.) , vol.85 , Issue.4 , pp. 227-234
    • Pandey, R.1    Khuller, G.K.2
  • 74
    • 84902246417 scopus 로고    scopus 로고
    • A rifapentine-containing inhaled triple antibiotic formulation for rapid treatment of tubercular infection
    • [74] Chan, J.G., et al. A rifapentine-containing inhaled triple antibiotic formulation for rapid treatment of tubercular infection. Pharm. Res. 31:5 (2014), 1239–1253.
    • (2014) Pharm. Res. , vol.31 , Issue.5 , pp. 1239-1253
    • Chan, J.G.1
  • 75
    • 50949086685 scopus 로고    scopus 로고
    • Intracellular time course, pharmacokinetics, and biodistribution of isoniazid and rifabutin following pulmonary delivery of inhalable microparticles to mice
    • [75] Verma, R.K., et al. Intracellular time course, pharmacokinetics, and biodistribution of isoniazid and rifabutin following pulmonary delivery of inhalable microparticles to mice. Antimicrob. Agents Chemother. 52:9 (2008), 3195–3201.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , Issue.9 , pp. 3195-3201
    • Verma, R.K.1
  • 76
    • 34248155773 scopus 로고    scopus 로고
    • Uptake of inhalable microparticles affects defence responses of macrophages infected with Mycobacterium tuberculosis H37Ra
    • [76] Sharma, R., et al. Uptake of inhalable microparticles affects defence responses of macrophages infected with Mycobacterium tuberculosis H37Ra. J. Antimicrob. Chemother. 59:3 (2007), 499–506.
    • (2007) J. Antimicrob. Chemother. , vol.59 , Issue.3 , pp. 499-506
    • Sharma, R.1
  • 77
    • 0034781469 scopus 로고    scopus 로고
    • Inhalable microparticles containing drug combinations to target alveolar macrophages for treatment of pulmonary tuberculosis
    • [77] Sharma, R., et al. Inhalable microparticles containing drug combinations to target alveolar macrophages for treatment of pulmonary tuberculosis. Pharm. Res. 18:10 (2001), 1405–1410.
    • (2001) Pharm. Res. , vol.18 , Issue.10 , pp. 1405-1410
    • Sharma, R.1
  • 78
    • 79551488013 scopus 로고    scopus 로고
    • Inhalable microparticles modify cytokine secretion by lung macrophages of infected mice
    • [78] Sharma, R., et al. Inhalable microparticles modify cytokine secretion by lung macrophages of infected mice. Tuberculosis (Edinb.) 91:1 (2011), 107–110.
    • (2011) Tuberculosis (Edinb.) , vol.91 , Issue.1 , pp. 107-110
    • Sharma, R.1
  • 79
    • 68249149640 scopus 로고    scopus 로고
    • Inhalable microparticles containing isoniazid and rifabutin target macrophages and ‘stimulate the phagocyte’ to achieve high efficacy
    • [79] Yadav, A.B., et al. Inhalable microparticles containing isoniazid and rifabutin target macrophages and ‘stimulate the phagocyte’ to achieve high efficacy. Indian J. Exp. Biol. 47:6 (2009), 469–474.
    • (2009) Indian J. Exp. Biol. , vol.47 , Issue.6 , pp. 469-474
    • Yadav, A.B.1
  • 80
    • 0042023529 scopus 로고    scopus 로고
    • Incorporation of antibiotics in liposomes designed for tuberculosis therapy by inhalation
    • [80] Justo, O.R., Moraes, A.M., Incorporation of antibiotics in liposomes designed for tuberculosis therapy by inhalation. Drug Deliv. 10:3 (2003), 201–207.
    • (2003) Drug Deliv. , vol.10 , Issue.3 , pp. 201-207
    • Justo, O.R.1    Moraes, A.M.2
  • 81
    • 0347519282 scopus 로고    scopus 로고
    • Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis
    • [81] Pandey, R., et al. Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis. J. Antimicrob. Chemother. 52:6 (2003), 981–986.
    • (2003) J. Antimicrob. Chemother. , vol.52 , Issue.6 , pp. 981-986
    • Pandey, R.1
  • 82
    • 34548009339 scopus 로고    scopus 로고
    • Inhalable microparticles containing large payload of anti-tuberculosis drugs
    • [82] Muttil, P., et al. Inhalable microparticles containing large payload of anti-tuberculosis drugs. Eur. J. Pharm. Sci. 32:2 (2007), 140–150.
    • (2007) Eur. J. Pharm. Sci. , vol.32 , Issue.2 , pp. 140-150
    • Muttil, P.1
  • 83
    • 84881479792 scopus 로고    scopus 로고
    • Isoniazid-gelatin conjugate microparticles containing rifampicin for the treatment of tuberculosis
    • [83] Manca, M.L., et al. Isoniazid-gelatin conjugate microparticles containing rifampicin for the treatment of tuberculosis. J. Pharm. Pharmacol. 65:9 (2013), 1302–1311.
    • (2013) J. Pharm. Pharmacol. , vol.65 , Issue.9 , pp. 1302-1311
    • Manca, M.L.1
  • 84
    • 84877855898 scopus 로고    scopus 로고
    • Phase I, single-dose, dose-escalating study of inhaled Dry powder capreomycin: a new approach to therapy of drug-resistant tuberculosis
    • [84] Dharmadhikari, A.S., et al. Phase I, single-dose, dose-escalating study of inhaled Dry powder capreomycin: a new approach to therapy of drug-resistant tuberculosis. Antimicrob. Agents Chemother. 57:6 (2013), 2613–2619.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , Issue.6 , pp. 2613-2619
    • Dharmadhikari, A.S.1
  • 85
    • 18044403109 scopus 로고    scopus 로고
    • Effect of chloroquine on phagolysosomal fusion in cultured guinea pig alveolar macrophages: implications in drug delivery
    • E34
    • [85] Bhat, M., Hickey, A.J., Effect of chloroquine on phagolysosomal fusion in cultured guinea pig alveolar macrophages: implications in drug delivery. AAPS PharmSci, 2(4), 2000, E34.
    • (2000) AAPS PharmSci , vol.2 , Issue.4
    • Bhat, M.1    Hickey, A.J.2
  • 86
    • 78649284183 scopus 로고    scopus 로고
    • Certain surfactants show promise in the therapy of pulmonary tuberculosis
    • [86] Stoops, J.K., et al. Certain surfactants show promise in the therapy of pulmonary tuberculosis. In Vivo 24:5 (2010), 687–694.
    • (2010) In Vivo , vol.24 , Issue.5 , pp. 687-694
    • Stoops, J.K.1
  • 87
    • 84899721353 scopus 로고    scopus 로고
    • Certain surfactants significantly enhance the activity of antibiotics in the mouse model of MTB and drug resistant MTB infection and effectively remove the bacteria from a pulmonary cavity in human ex-vivo study
    • [87] Risin, S.A., et al. Certain surfactants significantly enhance the activity of antibiotics in the mouse model of MTB and drug resistant MTB infection and effectively remove the bacteria from a pulmonary cavity in human ex-vivo study. Ann. Clin. Lab. Sci. 44:2 (2014), 117–122.
    • (2014) Ann. Clin. Lab. Sci. , vol.44 , Issue.2 , pp. 117-122
    • Risin, S.A.1
  • 89
    • 84878936028 scopus 로고    scopus 로고
    • Inhalable microparticles of nitric oxide donors induce phagosome maturation and kill Mycobacterium tuberculosis
    • [89] Verma, R.K., et al. Inhalable microparticles of nitric oxide donors induce phagosome maturation and kill Mycobacterium tuberculosis. Tuberculosis (Edinb.) 93:4 (2013), 412–417.
    • (2013) Tuberculosis (Edinb.) , vol.93 , Issue.4 , pp. 412-417
    • Verma, R.K.1
  • 90
    • 84868557865 scopus 로고    scopus 로고
    • Inhalable microparticles containing nitric oxide donors: saying NO to intracellular Mycobacterium tuberculosis
    • [90] Verma, R.K., et al. Inhalable microparticles containing nitric oxide donors: saying NO to intracellular Mycobacterium tuberculosis. Mol. Pharm. 9:11 (2012), 3183–3189.
    • (2012) Mol. Pharm. , vol.9 , Issue.11 , pp. 3183-3189
    • Verma, R.K.1
  • 91
    • 85012438725 scopus 로고
    • Regulatory science of inhalation aerosols
    • [91] Burke, G.P., Poochikian, G., Botstein, P., Regulatory science of inhalation aerosols. J. Aerosol Med. 4:3 (1991), 265–268.
    • (1991) J. Aerosol Med. , vol.4 , Issue.3 , pp. 265-268
    • Burke, G.P.1    Poochikian, G.2    Botstein, P.3
  • 92
    • 0028859518 scopus 로고
    • Delivery of biotherapeutics by inhalation aerosol
    • [92] Niven, R.W., Delivery of biotherapeutics by inhalation aerosol. Crit. Rev. Ther. Drug Carrier Syst. 12:2–3 (1995), 151–231.
    • (1995) Crit. Rev. Ther. Drug Carrier Syst. , vol.12 , Issue.2-3 , pp. 151-231
    • Niven, R.W.1
  • 93
    • 84929742263 scopus 로고    scopus 로고
    • Nebulizers for drug delivery to the lungs
    • [93] Martin, A.R., Finlay, W.H., Nebulizers for drug delivery to the lungs. Expert Opin. Drug Deliv. 12:6 (2015), 889–900.
    • (2015) Expert Opin. Drug Deliv. , vol.12 , Issue.6 , pp. 889-900
    • Martin, A.R.1    Finlay, W.H.2
  • 94
    • 84929754475 scopus 로고    scopus 로고
    • Generation of tailored aerosols for inhalative drug delivery employing recent vibrating-mesh nebulizer systems
    • [94] Bohr, A., Beck-Broichsitter, M., Generation of tailored aerosols for inhalative drug delivery employing recent vibrating-mesh nebulizer systems. Ther. Deliv. 6:5 (2015), 223–238.
    • (2015) Ther. Deliv. , vol.6 , Issue.5 , pp. 223-238
    • Bohr, A.1    Beck-Broichsitter, M.2
  • 95
    • 36649036141 scopus 로고    scopus 로고
    • Design of nanoparticle-based dry powder pulmonary vaccines
    • [95] Pulliam, B., Sung, J.C., Edwards, D.A., Design of nanoparticle-based dry powder pulmonary vaccines. Expert Opin. Drug Deliv. 4:6 (2007), 651–663.
    • (2007) Expert Opin. Drug Deliv. , vol.4 , Issue.6 , pp. 651-663
    • Pulliam, B.1    Sung, J.C.2    Edwards, D.A.3
  • 96
    • 84885849579 scopus 로고    scopus 로고
    • Dry powder antibiotic aerosol product development: inhaled therapy for tuberculosis
    • [96] Hickey, A.J., Misra, A., Fourie, P.B., Dry powder antibiotic aerosol product development: inhaled therapy for tuberculosis. J. Pharm. Sci. 102:11 (2013), 3900–3907.
    • (2013) J. Pharm. Sci. , vol.102 , Issue.11 , pp. 3900-3907
    • Hickey, A.J.1    Misra, A.2    Fourie, P.B.3
  • 97
    • 43349083052 scopus 로고    scopus 로고
    • Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin
    • [97] Fiegel, J., et al. Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin. Pharm. Res. 25:4 (2008), 805–811.
    • (2008) Pharm. Res. , vol.25 , Issue.4 , pp. 805-811
    • Fiegel, J.1
  • 98
    • 79961039597 scopus 로고    scopus 로고
    • Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere technology
    • [98] Geller, D.E., Weers, J., Heuerding, S., Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere technology. J. Aerosol Med. Pulm. Drug Deliv. 24:4 (2011), 175–182.
    • (2011) J. Aerosol Med. Pulm. Drug Deliv. , vol.24 , Issue.4 , pp. 175-182
    • Geller, D.E.1    Weers, J.2    Heuerding, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.