Hydrophobic ion pairing of isoniazid using a prodrug approach

Journal of Pharmaceutical Sciences

Volumn 91, Issue 6, 2002, Pages 1502-1511

  Zhou, Huiyu ^a   Lengsfeld, Corinne ^a   Claffey, David J ^b   Ruth, James A ^a,b   Hybertson, Brooks ^c   Randolph, Theodore W ^c   Ng, Ka Yun ^a   Manning, Mark C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b University of Denver   (United States)

^c UCB 450   (United States)

Author keywords

Hydrophobic ion pairing; Isoniazid; Prodrugs

Indexed keywords

AMMONIUM DERIVATIVE; DICHLOROMETHANE; ISONIAZID; MICROSPHERE; POLYLACTIDE; POLYMER; PRODRUG; SODIUM ISONIAZID METHANESULFONATE; TETRAHEPTYLAMMONIUM; TRIMETHYLAMMONIUM SALT DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG SOLUBILITY; ENCAPSULATION; HYDROPHOBICITY; LUNG TUBERCULOSIS; MICROENCAPSULATION; PARTITION COEFFICIENT; PRECIPITATION; SUPERCRITICAL FLUID;

EID: 0036285999     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10116     Document Type: Article

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