-
1
-
-
1842600276
-
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]
-
Kinasewitz GT, Yan SB, Basson B, Comp P, Russell JA, Cariou A, Um SL, Utterback B, Laterre PF, Dhainaut JF, PROWESS Sepsis Study Group. Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]. Crit Care. 2004;8:R82-90.
-
(2004)
Crit Care
, vol.8
, pp. R82-R90
-
-
Kinasewitz, G.T.1
Yan, S.B.2
Basson, B.3
Comp, P.4
Russell, J.A.5
Cariou, A.6
Um, S.L.7
Utterback, B.8
Laterre, P.F.9
Dhainaut, J.F.10
-
2
-
-
33748260015
-
Disseminated intravascular coagulation
-
Levi M, ten Cate H. Disseminated intravascular coagulation. N Engl J Med. 1999;341:586-92.
-
(1999)
N Engl J Med
, vol.341
, pp. 586-592
-
-
Levi, M.1
ten Cate, H.2
-
3
-
-
10644283860
-
Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation
-
Bakhtiari K, Meijers JC, de Jonge E, Levi M. Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation. Crit Care Med. 2004;32:2416-21.
-
(2004)
Crit Care Med
, vol.32
, pp. 2416-2421
-
-
Bakhtiari, K.1
Meijers, J.C.2
de Jonge, E.3
Levi, M.4
-
4
-
-
1842547895
-
Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation
-
Dhainaut JF, Yan SB, Joyce DE, Pettilä V, Basson B, Brandt JT, Sundin DP, Levi M. Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation. J Thromb Haemost. 2004;2:1924-33.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 1924-1933
-
-
Dhainaut, J.F.1
Yan, S.B.2
Joyce, D.E.3
Pettilä, V.4
Basson, B.5
Brandt, J.T.6
Sundin, D.P.7
Levi, M.8
-
5
-
-
84873714375
-
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.
-
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R. Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med. 2013;39(2):165-228.
-
(2013)
Intensive Care Med
, vol.39
, Issue.2
, pp. 165-228
-
-
Dellinger, R.P.1
Levy, M.M.2
Rhodes, A.3
Annane, D.4
Gerlach, H.5
Opal, S.M.6
Sevransky, J.E.7
Sprung, C.L.8
Douglas, I.S.9
Jaeschke, R.10
Osborn, T.M.11
Nunnally, M.E.12
Townsend, S.R.13
Reinhart, K.14
Kleinpell, R.M.15
Angus, D.C.16
Deutschman, C.S.17
Machado, F.R.18
Rubenfeld, G.D.19
Webb, S.20
Beale, R.J.21
Vincent, J.L.22
Moreno, R.23
more..
-
6
-
-
84873339299
-
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012
-
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R, Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2):580-637.
-
(2013)
Crit Care Med
, vol.41
, Issue.2
, pp. 580-637
-
-
Dellinger, R.P.1
Levy, M.M.2
Rhodes, A.3
Annane, D.4
Gerlach, H.5
Opal, S.M.6
Sevransky, J.E.7
Sprung, C.L.8
Douglas, I.S.9
Jaeschke, R.10
Osborn, T.M.11
Nunnally, M.E.12
Townsend, S.R.13
Reinhart, K.14
Kleinpell, R.M.15
Angus, D.C.16
Deutschman, C.S.17
Machado, F.R.18
Rubenfeld, G.D.19
Webb, S.A.20
Beale, R.J.21
Vincent, J.L.22
Moreno, R.23
more..
-
7
-
-
84979197941
-
Sepsis Registry Committee of The Japanese Society of Intensive Care Medicine. The Japanese guidelines for the management of sepsis
-
eCollection 2014
-
Oda S, Aibiki M, Ikeda T, Imaizumi H, Endo S, Ochiai R, Kotani J, Shime N, Nishida O, Noguchi T, Matsuda N, Hirasawa H. Sepsis Registry Committee of The Japanese Society of Intensive Care Medicine. The Japanese guidelines for the management of sepsis. J Intensive Care. 2014;2(1):55. doi:10.1186/s40560-014-0055-2. eCollection 2014.
-
(2014)
J Intensive Care
, vol.2
, Issue.1
, pp. 55
-
-
Oda, S.1
Aibiki, M.2
Ikeda, T.3
Imaizumi, H.4
Endo, S.5
Ochiai, R.6
Kotani, J.7
Shime, N.8
Nishida, O.9
Noguchi, T.10
Matsuda, N.11
Hirasawa, H.12
-
8
-
-
76449097783
-
Japanese Society of Thrombosis Hemostasis/DIC subcommittee: expert consensus for the treatment of disseminated intravascular coagulation in Japan
-
Wada H, Asakura H, Okamoto K, Iba T, Uchiyama T, Kawasugi K, Koga S, Mayumi T, Koike K, Gando S, Kushimoto S, Seki Y, Madoiwa S, Maruyama I, Yoshioka A. Japanese Society of Thrombosis Hemostasis/DIC subcommittee: expert consensus for the treatment of disseminated intravascular coagulation in Japan. Thromb Res. 2010;125:6-11.
-
(2010)
Thromb Res
, vol.125
, pp. 6-11
-
-
Wada, H.1
Asakura, H.2
Okamoto, K.3
Iba, T.4
Uchiyama, T.5
Kawasugi, K.6
Koga, S.7
Mayumi, T.8
Koike, K.9
Gando, S.10
Kushimoto, S.11
Seki, Y.12
Madoiwa, S.13
Maruyama, I.14
Yoshioka, A.15
-
9
-
-
84908201166
-
Addition of recommendations for the use of recombinant human thrombomodulin to the "Expert consensus for the treatment of disseminated intravascular coagulation in Japan"
-
Wada H, Okamoto K, Iba T, Kushimoto S, Kawasugi K, Gando S, Madoiwa S, Uchiyama T, Mayumi T, Seki Y, Japanese Society of Thrombosis Hemostasis/ DIC subcommittee. Addition of recommendations for the use of recombinant human thrombomodulin to the "Expert consensus for the treatment of disseminated intravascular coagulation in Japan". Thromb Res. 2014;134(4):924-5.
-
(2014)
Thromb Res
, vol.134
, Issue.4
, pp. 924-925
-
-
Wada, H.1
Okamoto, K.2
Iba, T.3
Kushimoto, S.4
Kawasugi, K.5
Gando, S.6
Madoiwa, S.7
Uchiyama, T.8
Mayumi, T.9
Seki, Y.10
-
10
-
-
74949117097
-
Inflammation and coagulation
-
Levi M, van der Poll T. Inflammation and coagulation. Crit Care Med. 2010;38:S26-34.
-
(2010)
Crit Care Med
, vol.38
, pp. S26-34
-
-
Levi, M.1
van der Poll, T.2
-
11
-
-
84866989789
-
The reciprocal relationship between inflammation and coagulation
-
O'Brien M. The reciprocal relationship between inflammation and coagulation. Top Companion Anim Med. 2012;27:46-52.
-
(2012)
Top Companion Anim Med
, vol.27
, pp. 46-52
-
-
O'Brien, M.1
-
12
-
-
0031057343
-
The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxemia
-
Levi M, van der Poll T, ten Cate H, van Deventer SJ. The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxemia. Eur J Clin Invest. 1997;27:3-9.
-
(1997)
Eur J Clin Invest
, vol.27
, pp. 3-9
-
-
Levi, M.1
van der Poll, T.2
ten Cate, H.3
van Deventer, S.J.4
-
13
-
-
84991034919
-
The mechanism behind coagulation disorders and organ dysfunction due to abdominal sepsis
-
(in Japanese)
-
Itoh H, Okamoto K. The mechanism behind coagulation disorders and organ dysfunction due to abdominal sepsis. J Abdomin Emerg Med. 2002;22(5):729-37 (in Japanese).
-
(2002)
J Abdomin Emerg Med
, vol.22
, Issue.5
, pp. 729-737
-
-
Itoh, H.1
Okamoto, K.2
-
14
-
-
0032525041
-
Potential mechanism for a proinflammatory vascular cytokine response to coagulation activation
-
Johnson K, Choi Y, DeGroot E, Samuels I, Creasey A, Aardwn I. Potential mechanism for a proinflammatory vascular cytokine response to coagulation activation. J Immunol. 1998;160:5130-5.
-
(1998)
J Immunol
, vol.160
, pp. 5130-5135
-
-
Johnson, K.1
Choi, Y.2
DeGroot, E.3
Samuels, I.4
Creasey, A.5
Aardwn, I.6
-
15
-
-
0029996796
-
The proinflammatory cytokine response to coagulation and endotoxin in whole blood
-
Johnson K, Aarden L, Choi Y, De Groot E, Creasey A. The proinflammatory cytokine response to coagulation and endotoxin in whole blood. Blood. 1996;87:5051-60.
-
(1996)
Blood
, vol.87
, pp. 5051-5060
-
-
Johnson, K.1
Aarden, L.2
Choi, Y.3
De Groot, E.4
Creasey, A.5
-
16
-
-
0034461642
-
Does inflammation contribute to thrombotic events?
-
Esmon CT. Does inflammation contribute to thrombotic events? Haemostasis. 2000;30 Suppl 2:34-40.
-
(2000)
Haemostasis
, vol.30
, pp. 34-40
-
-
Esmon, C.T.1
-
17
-
-
0030070996
-
Cell biology of tissue factor, the principal initiator of blood coagulation
-
Camerer E, Kolsto AB, Prydz H. Cell biology of tissue factor, the principal initiator of blood coagulation. Thromb Res. 1996;81:1-41.
-
(1996)
Thromb Res
, vol.81
, pp. 1-41
-
-
Camerer, E.1
Kolsto, A.B.2
Prydz, H.3
-
18
-
-
8944220715
-
Macrophages and neutrophils infiltrating into the liver are responsible for tissue factor expression in a rabbit model of acute obstructive cholangitis
-
Higure A, Okamoto K, Hirata K, Todoroki H, Nagafuchi Y, Takeda S, Katoh H, Itoh H, Ohsato K, Nakamura S. Macrophages and neutrophils infiltrating into the liver are responsible for tissue factor expression in a rabbit model of acute obstructive cholangitis. Thromb Haemost. 1996;75(5):791-5.
-
(1996)
Thromb Haemost
, vol.75
, Issue.5
, pp. 791-795
-
-
Higure, A.1
Okamoto, K.2
Hirata, K.3
Todoroki, H.4
Nagafuchi, Y.5
Takeda, S.6
Katoh, H.7
Itoh, H.8
Ohsato, K.9
Nakamura, S.10
-
19
-
-
0033965530
-
Neutrophils express tissue factor in a monkey model of sepsis
-
Todoroki H, Nakamura S, Higure A, Okamoto K, Takeda S, Nagata N, Itoh H, Ohsato K. Neutrophils express tissue factor in a monkey model of sepsis. Surgery. 2000;127(2):209-16.
-
(2000)
Surgery
, vol.127
, Issue.2
, pp. 209-216
-
-
Todoroki, H.1
Nakamura, S.2
Higure, A.3
Okamoto, K.4
Takeda, S.5
Nagata, N.6
Itoh, H.7
Ohsato, K.8
-
21
-
-
0034750626
-
Inhibition of factor Xa suppresses the expression of tissue factor in human monocytes and lipopolysaccharide induced endotoxemia in rats
-
Akahane K, Okamoto K, Kikuchi M, Todoroki H, Higure A, Sugiyama T, Kitahara K, Takeda S, Itoh H, Ohsato K. Inhibition of factor Xa suppresses the expression of tissue factor in human monocytes and lipopolysaccharide induced endotoxemia in rats. Surgery. 2001;130(5):809-18.
-
(2001)
Surgery
, vol.130
, Issue.5
, pp. 809-818
-
-
Akahane, K.1
Okamoto, K.2
Kikuchi, M.3
Todoroki, H.4
Higure, A.5
Sugiyama, T.6
Kitahara, K.7
Takeda, S.8
Itoh, H.9
Ohsato, K.10
-
22
-
-
34548835747
-
Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor
-
Tang H, Ivanciu L, Popescu N, Peer G, Hack E, Lupu C, Taylor FB Jr. Lupu F. Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor. Am J Pathol. 2007;171:1066-77.
-
(2007)
Am J Pathol
, vol.171
, pp. 1066-1077
-
-
Tang, H.1
Ivanciu, L.2
Popescu, N.3
Peer, G.4
Hack, E.5
Lupu, C.6
Taylor, F.B.7
Lupu, F.8
-
23
-
-
0036342697
-
Tissue factor production not balanced by tissue factor pathway inhibitor in sepsis promotes poor prognosis
-
Gando S, Kameue T, Morimoto Y, Matsuda N, Hayakawa M, Kemmotsu O. Tissue factor production not balanced by tissue factor pathway inhibitor in sepsis promotes poor prognosis. Crit Care Med. 2002;30:1729-34.
-
(2002)
Crit Care Med
, vol.30
, pp. 1729-1734
-
-
Gando, S.1
Kameue, T.2
Morimoto, Y.3
Matsuda, N.4
Hayakawa, M.5
Kemmotsu, O.6
-
24
-
-
0035891570
-
HMGB1 as a late mediator of lethal systemic inflammation
-
Wang H, Yang H, Czura CJ, Sama AE, Tracey KJ. HMGB1 as a late mediator of lethal systemic inflammation. Am J Respir Crit Care Med. 2001;164:1768-73.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1768-1773
-
-
Wang, H.1
Yang, H.2
Czura, C.J.3
Sama, A.E.4
Tracey, K.J.5
-
25
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ. HMG-1 as a late mediator of endotoxin lethality in mice. Science. 1999;285:248-51.
-
(1999)
Science
, vol.285
, pp. 248-251
-
-
Wang, H.1
Bloom, O.2
Zhang, M.3
Vishnubhakat, J.M.4
Ombrellino, M.5
Che, J.6
Frazier, A.7
Yang, H.8
Ivanova, S.9
Borovikova, L.10
Manogue, K.R.11
Faist, E.12
Abraham, E.13
Andersson, J.14
Andersson, U.15
Molina, P.E.16
Abumrad, N.N.17
Sama, A.18
Tracey, K.J.19
-
26
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 2002;418:191-5.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
27
-
-
0034795140
-
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
-
Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest. 2001;108:949-55.
-
(2001)
J Clin Invest
, vol.108
, pp. 949-955
-
-
Schmidt, A.M.1
Yan, S.D.2
Yan, S.F.3
Stern, D.M.4
-
28
-
-
0032816123
-
Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes
-
Wang H, Vishnubhakat JM, Bloom O, Zhang M, Ombrellino M, Sama A, Tracey KJ. Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes. Surgery. 1999;126:389-92.
-
(1999)
Surgery
, vol.126
, pp. 389-392
-
-
Wang, H.1
Vishnubhakat, J.M.2
Bloom, O.3
Zhang, M.4
Ombrellino, M.5
Sama, A.6
Tracey, K.J.7
-
29
-
-
84865511926
-
Novel role of PKR in inflammasome activation and HMGB1 release
-
Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson P, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 2012;488:670-4.
-
(2012)
Nature
, vol.488
, pp. 670-674
-
-
Lu, B.1
Nakamura, T.2
Inouye, K.3
Li, J.4
Tang, Y.5
Lundbäck, P.6
Valdes-Ferrer, S.I.7
Olofsson, P.8
Kalb, T.9
Roth, J.10
Zou, Y.11
Erlandsson-Harris, H.12
Yang, H.13
Ting, J.P.14
Wang, H.15
Andersson, U.16
Antoine, D.J.17
Chavan, S.S.18
Hotamisligil, G.S.19
Tracey, K.J.20
more..
-
30
-
-
84878408642
-
The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
-
Yang H, Antoine DJ, Andersson U, Tracey KJ. The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis. J Leukoc Biol. 2013;93:865-73.
-
(2013)
J Leukoc Biol
, vol.93
, pp. 865-873
-
-
Yang, H.1
Antoine, D.J.2
Andersson, U.3
Tracey, K.J.4
-
31
-
-
84979196664
-
PAMPs and DAMPs as triggers for DIC
-
Ito T. PAMPs and DAMPs as triggers for DIC. J Intensive Care. 2014;2(1):67.
-
(2014)
J Intensive Care
, vol.2
, Issue.1
, pp. 67
-
-
Ito, T.1
-
32
-
-
70449107044
-
Extracellular histones are major mediators of death in sepsis
-
Xu J, Zhang X, Pelayo R, Monestier M, Ammollo CT, Semerano F, Taylor FB, Esmon NL, Lupu F, Esmon CT. Extracellular histones are major mediators of death in sepsis. Nat Med. 2009;15:1318-21.
-
(2009)
Nat Med
, vol.15
, pp. 1318-1321
-
-
Xu, J.1
Zhang, X.2
Pelayo, R.3
Monestier, M.4
Ammollo, C.T.5
Semerano, F.6
Taylor, F.B.7
Esmon, N.L.8
Lupu, F.9
Esmon, C.T.10
-
33
-
-
70449112006
-
Sepsis: the dark side of histones
-
Chaput C, Zychlinsky A. Sepsis: the dark side of histones. Nat Med. 2009;15:1245-6.
-
(2009)
Nat Med
, vol.15
, pp. 1245-1246
-
-
Chaput, C.1
Zychlinsky, A.2
-
34
-
-
80051969149
-
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice
-
Huang H, Evankovich J, Yan W, Nace G, Zhang L, Ross M, Liao X, Billiar T, Xu J, Esmon CT, Tsung A. Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice. Hepatology. 2011;54:999-1008.
-
(2011)
Hepatology
, vol.54
, pp. 999-1008
-
-
Huang, H.1
Evankovich, J.2
Yan, W.3
Nace, G.4
Zhang, L.5
Ross, M.6
Liao, X.7
Billiar, T.8
Xu, J.9
Esmon, C.T.10
Tsung, A.11
-
35
-
-
84872555329
-
Circulating histones are mediators of trauma-associated lung injury
-
Abrams ST, Zhang N, Manson J, Liu T, Dart C, Baluwa F, Wang SS, Brohl K, Kipar A, Yu W, Wang G, Toh CH. Circulating histones are mediators of trauma-associated lung injury. Am J Respir Crit Care Med. 2013;187:160-9.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 160-169
-
-
Abrams, S.T.1
Zhang, N.2
Manson, J.3
Liu, T.4
Dart, C.5
Baluwa, F.6
Wang, S.S.7
Brohl, K.8
Kipar, A.9
Yu, W.10
Wang, G.11
Toh, C.H.12
-
36
-
-
77957652949
-
Extracellular DNA traps promote thrombosis
-
Fuchs TA, Brill A, Duerschmied D, Schatzberg D, Monestier M, Myers Jr DD, Wrobleski SK, Wakefield TW, Hartwig JH, Wagner DD. Extracellular DNA traps promote thrombosis. Proc Natl Acad Sci U S A. 2010;107:15880-5.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15880-15885
-
-
Fuchs, T.A.1
Brill, A.2
Duerschmied, D.3
Schatzberg, D.4
Monestier, M.5
Myers, D.D.6
Wrobleski, S.K.7
Wakefield, T.W.8
Hartwig, J.H.9
Wagner, D.D.10
-
37
-
-
80053354116
-
Histones induce rapid and profound thrombocytopenia in mice
-
Fuchs TA, Bhandari AA, Wagner DD. Histones induce rapid and profound thrombocytopenia in mice. Blood. 2011;118:3708-14.
-
(2011)
Blood
, vol.118
, pp. 3708-3714
-
-
Fuchs, T.A.1
Bhandari, A.A.2
Wagner, D.D.3
-
38
-
-
77949305755
-
Inflammation, innate immunity and blood coagulation
-
Xu J, Lupu F, Esmon CT. Inflammation, innate immunity and blood coagulation. Hamostaseologie. 2010;30:5-9.
-
(2010)
Hamostaseologie
, vol.30
, pp. 5-9
-
-
Xu, J.1
Lupu, F.2
Esmon, C.T.3
-
39
-
-
84884752631
-
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism
-
Nakahara M, Ito T, Kawahara K, Yamamoto M, Nagasato T, Shrestha B, Yamada S, Miyauchi T, Higuchi K, Takenaka T, Yasuda T, Matsunaga A, Kakihana Y, Hashiguchi T, Kanmura Y, Maruyama I. Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism. PLoS One. 2013;8(9):e75961.
-
(2013)
PLoS One
, vol.8
, Issue.9
-
-
Nakahara, M.1
Ito, T.2
Kawahara, K.3
Yamamoto, M.4
Nagasato, T.5
Shrestha, B.6
Yamada, S.7
Miyauchi, T.8
Higuchi, K.9
Takenaka, T.10
Yasuda, T.11
Matsunaga, A.12
Kakihana, Y.13
Hashiguchi, T.14
Kanmura, Y.15
Maruyama, I.16
-
40
-
-
0035160476
-
Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation
-
Taylor FB, Toh CH, Hoots WK, Wada H, Levi M. Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost. 2001;86:1327-30.
-
(2001)
Thromb Haemost
, vol.86
, pp. 1327-1330
-
-
Taylor, F.B.1
Toh, C.H.2
Hoots, W.K.3
Wada, H.4
Levi, M.5
-
41
-
-
0021087622
-
Criteria for diagnosis of DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the Research Committee on DIC in Japan
-
Kobayashi N, Maegawa T, Takada M, Tanaka H, Gonmori H. Criteria for diagnosis of DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the Research Committee on DIC in Japan. Bibl Haematol. 1983;49:265-75.
-
(1983)
Bibl Haematol
, vol.49
, pp. 265-275
-
-
Kobayashi, N.1
Maegawa, T.2
Takada, M.3
Tanaka, H.4
Gonmori, H.5
-
42
-
-
33644589346
-
A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: comparing current criteria
-
Gando S, Iba T, Eguchi Y, Ohtomo Y, Okamoto K, Koseki K, Mayumi T, Murata A, Ikeda T, Ishikura H, Ueyama M, Ogura H, Kushimoto S, Saitoh D, Endo S, Shimazaki S, Japanese Association for Acute Medicine Disseminated Intravascular Coagulation (JAAM DIC) Study Group. A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: comparing current criteria. Crit Care Med. 2006;34:625-31.
-
(2006)
Crit Care Med
, vol.34
, pp. 625-631
-
-
Gando, S.1
Iba, T.2
Eguchi, Y.3
Ohtomo, Y.4
Okamoto, K.5
Koseki, K.6
Mayumi, T.7
Murata, A.8
Ikeda, T.9
Ishikura, H.10
Ueyama, M.11
Ogura, H.12
Kushimoto, S.13
Saitoh, D.14
Endo, S.15
Shimazaki, S.16
-
43
-
-
34548680947
-
SIRS-associated coagulopathy and organ dysfunction in critically ill patients with thrombocytopenia
-
Ogura H, Gando S, Iba T, Eguchi Y, Ohtomo Y, Okamoto K, Koseki K, Mayumi T, Murata A, Ikeda T, Ishikura H, Ueyama M, Kushimoto S, Saitoh D, Endo S, Shimazaki S. Japanese Association for Acute Medicine Disseminated Intravascular Coagulation (JAAM DIC) Study Group. SIRS-associated coagulopathy and organ dysfunction in critically ill patients with thrombocytopenia. Shock. 2007;28:411-7.
-
(2007)
Shock
, vol.28
, pp. 411-417
-
-
Ogura, H.1
Gando, S.2
Iba, T.3
Eguchi, Y.4
Ohtomo, Y.5
Okamoto, K.6
Koseki, K.7
Mayumi, T.8
Murata, A.9
Ikeda, T.10
Ishikura, H.11
Ueyama, M.12
Kushimoto, S.13
Saitoh, D.14
Endo, S.15
Shimazaki, S.16
-
44
-
-
78651102024
-
Prospective evaluation of three different diagnostic criteria for disseminated intravascular coagulation
-
Takemitsu T, Wada H, Hatada T, Ohmori Y, Ishikura K, Takeda T, Sugiyama T, Yamada N, Maruyama K, Katayama N, Isaji S, Shimpo H, Kusunoki M, Nobori T. Prospective evaluation of three different diagnostic criteria for disseminated intravascular coagulation. Thromb Haemost. 2011;105:40-4.
-
(2011)
Thromb Haemost
, vol.105
, pp. 40-44
-
-
Takemitsu, T.1
Wada, H.2
Hatada, T.3
Ohmori, Y.4
Ishikura, K.5
Takeda, T.6
Sugiyama, T.7
Yamada, N.8
Maruyama, K.9
Katayama, N.10
Isaji, S.11
Shimpo, H.12
Kusunoki, M.13
Nobori, T.14
-
45
-
-
0029082904
-
Outcome of disseminated intravascular coagulation in relation to the score when treatment was begun
-
Wada H, Wakita Y, Nakase T, Shimura M, Hiyoyama K, Nagaya S, Mori Y, Shiku H. Outcome of disseminated intravascular coagulation in relation to the score when treatment was begun. Thromb Haemost. 1995;74:848-52.
-
(1995)
Thromb Haemost
, vol.74
, pp. 848-852
-
-
Wada, H.1
Wakita, Y.2
Nakase, T.3
Shimura, M.4
Hiyoyama, K.5
Nagaya, S.6
Mori, Y.7
Shiku, H.8
-
46
-
-
77953122371
-
Frequency and hemostatic abnormalities in pre-DIC patients
-
Okamoto K, Wada H, Hatada T, Uchiyama T, Kawasugi K, Mayumi T, Gando S, Kushimoto S, Seki Y, Madoiwa S, Asakura H, Koga S, Iba T, Maruyama I, Japanese Society of Thrombosis Hemostasis/DIC subcommittee. Frequency and hemostatic abnormalities in pre-DIC patients. Thromb Res. 2010;126:74-8.
-
(2010)
Thromb Res
, vol.126
, pp. 74-78
-
-
Okamoto, K.1
Wada, H.2
Hatada, T.3
Uchiyama, T.4
Kawasugi, K.5
Mayumi, T.6
Gando, S.7
Kushimoto, S.8
Seki, Y.9
Madoiwa, S.10
Asakura, H.11
Koga, S.12
Iba, T.13
Maruyama, I.14
-
47
-
-
0015821564
-
The purification and mechanism of action of human antithrombin-heparin cofactor
-
Rosenberg RD, Damus PS. The purification and mechanism of action of human antithrombin-heparin cofactor. J Biol Chem. 1973;248:6490-505.
-
(1973)
J Biol Chem
, vol.248
, pp. 6490-6505
-
-
Rosenberg, R.D.1
Damus, P.S.2
-
48
-
-
0035904368
-
High-dose antithrombin in severe sepsis
-
Warren BL, Eid A, Singer P, Pillay SS, Carl P, Novak I, Chalupa P, Atherstone A, Pénzes I, Kübler A, Knaub S, Keinecke HO, Heinrichs H, Schindel F, Juers M, Bone RC, Opal SM; KyberSept Trial Study Group. High-dose antithrombin in severe sepsis. A randomized controlled trial. JAMA. 2001;286:1869-78.
-
(2001)
A randomized controlled trial. JAMA
, vol.286
, pp. 1869-1878
-
-
Warren, B.L.1
Eid, A.2
Singer, P.3
Pillay, S.S.4
Carl, P.5
Novak, I.6
Chalupa, P.7
Atherstone, A.8
Pénzes, I.9
Kübler, A.10
Knaub, S.11
Keinecke, H.O.12
Heinrichs, H.13
Schindel, F.14
Juers, M.15
Bone, R.C.16
Opal, S.M.17
-
49
-
-
0024451154
-
Therapeutic use of antithrombin III in shock and disseminated intravascular coagulation
-
Vinazzer H. Therapeutic use of antithrombin III in shock and disseminated intravascular coagulation. Semin Thromb Hemost. 1989;15:347-52.
-
(1989)
Semin Thromb Hemost
, vol.15
, pp. 347-352
-
-
Vinazzer, H.1
-
50
-
-
0026311493
-
Clinical study of the therapeutic value of Kybernin in the treatment of antithrombin III deficiency
-
Dzinic L, Marenovic T, Lakic-Trajkovic Z. Clinical study of the therapeutic value of Kybernin in the treatment of antithrombin III deficiency. Med Pregl. 1991;44:245-8.
-
(1991)
Med Pregl
, vol.44
, pp. 245-248
-
-
Dzinic, L.1
Marenovic, T.2
Lakic-Trajkovic, Z.3
-
51
-
-
0026462921
-
Effect of antithrombin concentrate on haemostatic variables in critically ill patients
-
Albert J, Blomqvist H, Gardlund B, Jakobsson J, Svensson J, Blombäck M. Effect of antithrombin concentrate on haemostatic variables in critically ill patients. Acta Anaesthesiol Scand. 1992;36:745-52.
-
(1992)
Acta Anaesthesiol Scand
, vol.36
, pp. 745-752
-
-
Albert, J.1
Blomqvist, H.2
Gardlund, B.3
Jakobsson, J.4
Svensson, J.5
Blombäck, M.6
-
52
-
-
0027171963
-
Double-blind, placebocontrolled trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation
-
Fourrier F, Chopin C, Huart JJ, Runge I, Caron C, Goudemand J. Double-blind, placebocontrolled trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation. Chest. 1993;104:882-8.
-
(1993)
Chest
, vol.104
, pp. 882-888
-
-
Fourrier, F.1
Chopin, C.2
Huart, J.J.3
Runge, I.4
Caron, C.5
Goudemand, J.6
-
53
-
-
0031728553
-
High-dose antithrombin III treatment of severely injured patients: results of a prospective study
-
Waydhas C, Nast-Kolb D, Gippner-Steppert C, Trupka A, Pfundstein C, Schweiberer L, Jochum M. High-dose antithrombin III treatment of severely injured patients: results of a prospective study. J Trauma. 1998;45:931-40.
-
(1998)
J Trauma
, vol.45
, pp. 931-940
-
-
Waydhas, C.1
Nast-Kolb, D.2
Gippner-Steppert, C.3
Trupka, A.4
Pfundstein, C.5
Schweiberer, L.6
Jochum, M.7
-
54
-
-
7144251856
-
Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled doubleblind, randomized, multicenter study
-
Baudo F, Caimi TM, de Cataldo F, Ravizza A, Arlati S, Casella G, Carugo D, Palareti G, Legnani C, Ridolfi L, Rossi R, D'Angelo A, Crippa L, Giudici D, Gallioli G, Wolfler A, Calori G. Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled doubleblind, randomized, multicenter study. Intensive Care Med. 1998;24:336-42.
-
(1998)
Intensive Care Med
, vol.24
, pp. 336-342
-
-
Baudo, F.1
Caimi, T.M.2
de Cataldo, F.3
Ravizza, A.4
Arlati, S.5
Casella, G.6
Carugo, D.7
Palareti, G.8
Legnani, C.9
Ridolfi, L.10
Rossi, R.11
D'Angelo, A.12
Crippa, L.13
Giudici, D.14
Gallioli, G.15
Wolfler, A.16
Calori, G.17
-
55
-
-
0031825290
-
Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a metaanalysis on all randomized, placebo-controlled, double blind trials with antithrombin III in severe sepsis
-
Eisele B, Lamy M, Thijs LG, Keinecke HO, Schuster HP, Matthias FR, Fourrier F, Heinrichs H, Delvos U. Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a metaanalysis on all randomized, placebo-controlled, double blind trials with antithrombin III in severe sepsis. Intensive CareMed. 1998;24:663-72.
-
(1998)
Intensive CareMed
, vol.24
, pp. 663-672
-
-
Eisele, B.1
Lamy, M.2
Thijs, L.G.3
Keinecke, H.O.4
Schuster, H.P.5
Matthias, F.R.6
Fourrier, F.7
Heinrichs, H.8
Delvos, U.9
-
56
-
-
4444237509
-
Effect of long-term and high-dose antithrombin supplementation on coagulation and fibrinolysis in patients with severe sepsis
-
Hoffmann JN, Muhlbayer D, Jochum M, Inthorn D. Effect of long-term and high-dose antithrombin supplementation on coagulation and fibrinolysis in patients with severe sepsis. Crit Care Med. 2004;32:1851-9.
-
(2004)
Crit Care Med
, vol.32
, pp. 1851-1859
-
-
Hoffmann, J.N.1
Muhlbayer, D.2
Jochum, M.3
Inthorn, D.4
-
57
-
-
33644859949
-
Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation
-
Kienast J, Juers M, Wiedermann CJ, Hoffmann JN, Ostermann H, Strauss R, Keinecke HO, Warren BL, Opal SM, KyberSept investigators. Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation. J Thromb Haemost. 2006;4:90-7.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 90-97
-
-
Kienast, J.1
Juers, M.2
Wiedermann, C.J.3
Hoffmann, J.N.4
Ostermann, H.5
Strauss, R.6
Keinecke, H.O.7
Warren, B.L.8
Opal, S.M.9
-
58
-
-
33748926949
-
A systematic review of antithrombin concentrate use in patients with disseminated intravascular coagulation of severe sepsis
-
Wiedermann CJ, Kaneider N. A systematic review of antithrombin concentrate use in patients with disseminated intravascular coagulation of severe sepsis. Blood Coagul Fibrinolysis. 2006;17:521-6.
-
(2006)
Blood Coagul Fibrinolysis
, vol.17
, pp. 521-526
-
-
Wiedermann, C.J.1
Kaneider, N.2
-
59
-
-
84865252092
-
Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a prospective multicenter survey
-
Iba T, Saito D, Wada H, Asakura H. Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a prospective multicenter survey. Thromb Res. 2012;130:e129-33.
-
(2012)
Thromb Res
, vol.130
, pp. e129-e133
-
-
Iba, T.1
Saito, D.2
Wada, H.3
Asakura, H.4
-
60
-
-
84907721570
-
Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a secondary survey
-
Iba T, Saitoh D, Wada H, Asakura H. Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a secondary survey. Crit Care. 2014;18:497.
-
(2014)
Crit Care
, vol.18
, pp. 497
-
-
Iba, T.1
Saitoh, D.2
Wada, H.3
Asakura, H.4
-
61
-
-
84890278513
-
A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis
-
Gando S, Saitoh D, Ishikura H, Ueyama M, Otomo Y, Oda S, Kushimoto S, Tanjoh K, Mayumi T, Ikeda T, Iba T, Eguchi Y, Okamoto K, Ogura H, Koseki K, Sakamoto Y, Takayama Y, Shirai K, Takasu O, Inoue Y, Mashiko K, Tsubota T, Endo S. A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis. Crit Care. 2013;17:R297.
-
(2013)
Crit Care
, vol.17
, pp. R297
-
-
Gando, S.1
Saitoh, D.2
Ishikura, H.3
Ueyama, M.4
Otomo, Y.5
Oda, S.6
Kushimoto, S.7
Tanjoh, K.8
Mayumi, T.9
Ikeda, T.10
Iba, T.11
Eguchi, Y.12
Okamoto, K.13
Ogura, H.14
Koseki, K.15
Sakamoto, Y.16
Takayama, Y.17
Shirai, K.18
Takasu, O.19
Inoue, Y.20
Mashiko, K.21
Tsubota, T.22
Endo, S.23
more..
-
62
-
-
84908469647
-
Antithrombin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study
-
Tagami T, Matsui H, Horiguchi H, Fushimi K, Yasunaga H. Antithrombin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study. J Thromb Haemost. 2014;12:1470-9.
-
(2014)
J Thromb Haemost
, vol.12
, pp. 1470-1479
-
-
Tagami, T.1
Matsui, H.2
Horiguchi, H.3
Fushimi, K.4
Yasunaga, H.5
-
63
-
-
0027383665
-
Clinical evaluation of low-molecular-weight heparin (FR-860) on disseminated intravascular coagulation (DIC)-a multicenter co-operative double-blind trial in comparison with heparin
-
Sakuragawa N, Hasegawa H, Maki M, Nakagawa M, Nakashima M. Clinical evaluation of low-molecular-weight heparin (FR-860) on disseminated intravascular coagulation (DIC)-a multicenter co-operative double-blind trial in comparison with heparin. Thromb Res. 1993;72:475-500.
-
(1993)
Thromb Res
, vol.72
, pp. 475-500
-
-
Sakuragawa, N.1
Hasegawa, H.2
Maki, M.3
Nakagawa, M.4
Nakashima, M.5
-
64
-
-
67650470156
-
Unfractioned heparin for treatment of sepsis: a randomized clinical trial (The HETRASE study)
-
Jaimes F, De La Rosa G, Morales C, Fortich F, Arango C, Aguirre D, Munoz A. Unfractioned heparin for treatment of sepsis: a randomized clinical trial (The HETRASE study). Crit Care Med. 2009;37:1185-96.
-
(2009)
Crit Care Med
, vol.37
, pp. 1185-1196
-
-
Jaimes, F.1
De La Rosa, G.2
Morales, C.3
Fortich, F.4
Arango, C.5
Aguirre, D.6
Munoz, A.7
-
65
-
-
84924230426
-
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis
-
Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hébert P, Cook DJ, Fergusson DA, Canadian Critical Care Trials Group. The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis. Crit Care Med. 2015;43:511-28.
-
(2015)
Crit Care Med
, vol.43
, pp. 511-528
-
-
Zarychanski, R.1
Abou-Setta, A.M.2
Kanji, S.3
Turgeon, A.F.4
Kumar, A.5
Houston, D.S.6
Rimmer, E.7
Houston, B.L.8
McIntyre, L.9
Fox-Robichaud, A.E.10
Hébert, P.11
Cook, D.J.12
Fergusson, D.A.13
Canadian Critical Care Trials, Group.14
-
66
-
-
84988715283
-
Heparin therapy reduces 28-day mortality in adult severe sepsis patients: a systematic review and meta-analysis
-
Wang C, Chi C, Guo L, Wang X, Guo L, Sun J, Sun B, Liu S, Chang X, Li E. Heparin therapy reduces 28-day mortality in adult severe sepsis patients: a systematic review and meta-analysis. Crit Care. 2014;18:563.
-
(2014)
Crit Care
, vol.18
, pp. 563
-
-
Wang, C.1
Chi, C.2
Guo, L.3
Wang, X.4
Guo, L.5
Sun, J.6
Sun, B.7
Liu, S.8
Chang, X.9
Li, E.10
-
67
-
-
85132478420
-
Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction
-
Epub 2015 Dec 29
-
Iba T, Hashiguchi N, Nagaoka I, Tabe Y, Kadota K, Sato K. Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction. Intensive Care Med Exp. 2015;3(1):36. doi:10.1186/s40635-015-0072-z. Epub 2015 Dec 29.
-
(2015)
Intensive Care Med Exp
, vol.3
, Issue.1
, pp. 36
-
-
Iba, T.1
Hashiguchi, N.2
Nagaoka, I.3
Tabe, Y.4
Kadota, K.5
Sato, K.6
-
68
-
-
33644801469
-
The interactions between inflammation and coagulation
-
Esmon CT. The interactions between inflammation and coagulation. Br J Haematol. 2005;131:417-30.
-
(2005)
Br J Haematol
, vol.131
, pp. 417-430
-
-
Esmon, C.T.1
-
69
-
-
0023096623
-
The regulation of natural anticoagulant pathways
-
Esmon CT. The regulation of natural anticoagulant pathways. Science. 1987;235:1348-52.
-
(1987)
Science
, vol.235
, pp. 1348-1352
-
-
Esmon, C.T.1
-
70
-
-
0027998013
-
Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN gamma, or phorbol ester
-
Grey ST, Tsuchida A, Hau H, Orthner CL, Salem HH, Hancock WW. Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN gamma, or phorbol ester. J Immunol. 1994;153:3664-72.
-
(1994)
J Immunol
, vol.153
, pp. 3664-3672
-
-
Grey, S.T.1
Tsuchida, A.2
Hau, H.3
Orthner, C.L.4
Salem, H.H.5
Hancock, W.W.6
-
71
-
-
20944436774
-
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism
-
Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I. The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J Clin Invest. 2005;115:1267-74.
-
(2005)
J Clin Invest
, vol.115
, pp. 1267-1274
-
-
Abeyama, K.1
Stern, D.M.2
Ito, Y.3
Kawahara, K.4
Yoshimoto, Y.5
Tanaka, M.6
Uchimura, T.7
Ida, N.8
Yamazaki, Y.9
Yamada, S.10
Yamamoto, Y.11
Yamamoto, H.12
Iino, S.13
Taniguchi, N.14
Maruyama, I.15
-
72
-
-
53449087278
-
Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes
-
Ito T, Kawahara K, Okamoto K, Yamada S, Yasuda M, Imaizumi H, Nawa Y, Meug X, Shrestha B, Hashiguchi T, Maruyama I. Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes. Arterioscler Thromb Biol. 2008;28:1825-30.
-
(2008)
Arterioscler Thromb Biol
, vol.28
, pp. 1825-1830
-
-
Ito, T.1
Kawahara, K.2
Okamoto, K.3
Yamada, S.4
Yasuda, M.5
Imaizumi, H.6
Nawa, Y.7
Meug, X.8
Shrestha, B.9
Hashiguchi, T.10
Maruyama, I.11
-
73
-
-
67649766887
-
Recombinant human soluble thrombomodulin (ART-123) decreases the plasma HMGB1 levels, while improving the acute liver injury and survival rates in experimental endotoxemia
-
Nagato M, Okamoto K, Abe Y, Higure A, Yamaguchi K. Recombinant human soluble thrombomodulin (ART-123) decreases the plasma HMGB1 levels, while improving the acute liver injury and survival rates in experimental endotoxemia. Crit Care Med. 2009;37:2181-6.
-
(2009)
Crit Care Med
, vol.37
, pp. 2181-2186
-
-
Nagato, M.1
Okamoto, K.2
Abe, Y.3
Higure, A.4
Yamaguchi, K.5
-
74
-
-
33845513582
-
Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial
-
Saito H, Maruyama I, Shimazaki S, Yamamoto Y, Aikawa N, Ohno R, Hirayama A, Matsuda T, Asakura H, Nakashima M, Aoki N. Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial. J Thromb Haemost. 2007;5:31-41.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 31-41
-
-
Saito, H.1
Maruyama, I.2
Shimazaki, S.3
Yamamoto, Y.4
Aikawa, N.5
Ohno, R.6
Hirayama, A.7
Matsuda, T.8
Asakura, H.9
Nakashima, M.10
Aoki, N.11
-
75
-
-
79961081848
-
Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial
-
Aikawa N, Shimazaki S, Yamamoto Y, Saito H, Maruyama I, Ohno R, Hirayama A, Aoki Y, Aoki N. Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial. Shock. 2011;35:349-54.
-
(2011)
Shock
, vol.35
, pp. 349-354
-
-
Aikawa, N.1
Shimazaki, S.2
Yamamoto, Y.3
Saito, H.4
Maruyama, I.5
Ohno, R.6
Hirayama, A.7
Aoki, Y.8
Aoki, N.9
-
76
-
-
84883615933
-
A randomized, double-blind, placebo-controlled, phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation
-
Vincent JL, Ramesh MK, Ernest D, Larosa SP, Pach J, Aikawa N, Hoste E, Levy H, Hirman J, Levi M, Daga M, Kutsogiannis DJ, Crowther M, Bernard GR, Devriendt J, Puigserver JV, Blanzaco DU, Esmon CT, Parrillo JE, Guzzi L, Henderson SJ, Pothirat C, Mehta P, Fareed J, Talwar D, Tsuruta K, Gorelick KJ, Osawa Y, Kaul I. A randomized, double-blind, placebo-controlled, phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Crit Care Med. 2013;41:2069-79.
-
(2013)
Crit Care Med
, vol.41
, pp. 2069-2079
-
-
Vincent, J.L.1
Ramesh, M.K.2
Ernest, D.3
Larosa, S.P.4
Pach, J.5
Aikawa, N.6
Hoste, E.7
Levy, H.8
Hirman, J.9
Levi, M.10
Daga, M.11
Kutsogiannis, D.J.12
Crowther, M.13
Bernard, G.R.14
Devriendt, J.15
Puigserver, J.V.16
Blanzaco, D.U.17
Esmon, C.T.18
Parrillo, J.E.19
Guzzi, L.20
Henderson, S.J.21
Pothirat, C.22
Mehta, P.23
Fareed, J.24
Talwar, D.25
Tsuruta, K.26
Gorelick, K.J.27
Osawa, Y.28
Kaul, I.29
more..
-
77
-
-
84921047896
-
Recombinant human soluble thrombomodulin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study
-
Tagami T, Matsui H, Horiguchi H, Fushimmi K, Yasunaga H. Recombinant human soluble thrombomodulin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study. J Thromb Haemost. 2015;13:31-40.
-
(2015)
J Thromb Haemost
, vol.13
, pp. 31-40
-
-
Tagami, T.1
Matsui, H.2
Horiguchi, H.3
Fushimmi, K.4
Yasunaga, H.5
-
78
-
-
84906934935
-
The recent time trend of outcomes of disseminated intravascular coagulation in Japan: an observational study based on a national administrative database
-
Murata A, Okamoto K, Mayumi T, Muramatsu K, Matsuda S. The recent time trend of outcomes of disseminated intravascular coagulation in Japan: an observational study based on a national administrative database. J Thrombosis Thrombolysis. 2014;38(3):364-71.
-
(2014)
J Thrombosis Thrombolysis
, vol.38
, Issue.3
, pp. 364-371
-
-
Murata, A.1
Okamoto, K.2
Mayumi, T.3
Muramatsu, K.4
Matsuda, S.5
-
79
-
-
84964292230
-
Observational study to compare antithrombin and thrombomodulin for disseminated intravascular coagulation
-
Murata A, Okamoto K, Mayumi T, Muramatsu K, Matsuda S. Observational study to compare antithrombin and thrombomodulin for disseminated intravascular coagulation. Int J Clin Pharm. 2015;37(1):139-47.
-
(2015)
Int J Clin Pharm
, vol.37
, Issue.1
, pp. 139-147
-
-
Murata, A.1
Okamoto, K.2
Mayumi, T.3
Muramatsu, K.4
Matsuda, S.5
-
80
-
-
84951336287
-
Recent change in treatment of disseminated intravascular coagulation in Japan: an epidemiological study based on a National Administrative Database
-
Murata A, Okamoto K, Mayumi T, Muramatsu K, Matsuda S. Recent change in treatment of disseminated intravascular coagulation in Japan: an epidemiological study based on a National Administrative Database. Clin Appl Thromb Hemost. 2016;22:21-27.
-
(2016)
Clin Appl Thromb Hemost
, vol.22
, pp. 21-27
-
-
Murata, A.1
Okamoto, K.2
Mayumi, T.3
Muramatsu, K.4
Matsuda, S.5
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