메뉴 건너뛰기




Volumn 214, Issue , 2016, Pages S75-S82

From Wasting to Obesity: The Contribution of Nutritional Status to Immune Activation in HIV Infection

Author keywords

adipose tissue; HIV; immune activation; inflammation; malnutrition; obesity

Indexed keywords

ADIPOCYTOKINE; BIOLOGICAL MARKER;

EID: 84990938578     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiw286     Document Type: Article
Times cited : (23)

References (50)
  • 1
    • 84969384618 scopus 로고    scopus 로고
    • Obesity trends and body mass index changes after starting antiretroviral treatment: The Swiss HIV Cohort Study
    • Hasse B, Iff M, Ledergerber B, et al. Obesity trends and body mass index changes after starting antiretroviral treatment: The Swiss HIV Cohort Study. Open Forum Infect Dis 2014; 1: 40.
    • (2014) Open Forum Infect Dis , vol.1 , pp. 40
    • Hasse, B.1    Iff, M.2    Ledergerber, B.3
  • 2
    • 84954186194 scopus 로고    scopus 로고
    • Rising obesity prevalence and weight gain among adults starting antiretroviral therapy in the United States and Canada
    • Koethe JR, Jenkins CA, Lau B, et al. Rising obesity prevalence and weight gain among adults starting antiretroviral therapy in the United States and Canada. AIDS Res Hum Retroviruses 2016; 32:50-8.
    • (2016) AIDS Res Hum Retroviruses , vol.32 , pp. 50-58
    • Koethe, J.R.1    Jenkins, C.A.2    Lau, B.3
  • 3
    • 77950511903 scopus 로고    scopus 로고
    • Nutritional aspects of HIV-associated wasting in sub-Saharan Africa
    • Koethe JR, Heimburger DC. Nutritional aspects of HIV-associated wasting in sub-Saharan Africa. Am J Clin Nutr 2010; 91:1138S-42.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1138S-1138S42
    • Koethe, J.R.1    Heimburger, D.C.2
  • 4
    • 0024446834 scopus 로고
    • Magnitude of body-cell-mass depletion and the timing of death from wasting in AIDS
    • Kotler DP, Tierney AR, Wang J, Pierson RN Jr. Magnitude of body-cell-mass depletion and the timing of death from wasting in AIDS. Am J Clin Nutr 1989; 50:444-7.
    • (1989) Am J Clin Nutr , vol.50 , pp. 444-447
    • Kotler, D.P.1    Tierney, A.R.2    Wang, J.3    Pierson, R.N.4
  • 5
    • 0029004922 scopus 로고
    • Energy expenditure and wasting in human immunodeficiency virus infection
    • Macallan DC, Noble C, Baldwin C, et al. Energy expenditure and wasting in human immunodeficiency virus infection. N Engl J Med 1995; 333:83-8.
    • (1995) N Engl J Med , vol.333 , pp. 83-88
    • MacAllan, D.C.1    Noble, C.2    Baldwin, C.3
  • 6
    • 0026547557 scopus 로고
    • Resting energy expenditure, caloric intake, and short-term weight change in human immunodeficiency virus infection and the acquired immunodeficiency syndrome
    • Grunfeld C, Pang M, Shimizu L, Shigenaga JK, Jensen P, Feingold KR. Resting energy expenditure, caloric intake, and short-term weight change in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. Am J Clin Nutr 1992; 55:455-60.
    • (1992) Am J Clin Nutr , vol.55 , pp. 455-460
    • Grunfeld, C.1    Pang, M.2    Shimizu, L.3    Shigenaga, J.K.4    Jensen, P.5    Feingold, K.R.6
  • 7
    • 0032859850 scopus 로고    scopus 로고
    • Elevated resting energy expenditure among HIV-seropositive persons receiving highly active antiretroviral therapy
    • Shevitz AH, Knox TA, Spiegelman D, Roubenoff R, Gorbach SL, Skolnik PR. Elevated resting energy expenditure among HIV-seropositive persons receiving highly active antiretroviral therapy. AIDS 1999; 13:1351-7.
    • (1999) AIDS , vol.13 , pp. 1351-1357
    • Shevitz, A.H.1    Knox, T.A.2    Spiegelman, D.3    Roubenoff, R.4    Gorbach, S.L.5    Skolnik, P.R.6
  • 8
    • 0027277122 scopus 로고
    • Resting energy expenditure in human immunodeficiency virus-infected patients: Comparison between patients with and without secondary infections
    • Melchior JC, Raguin G, Boulier A, et al. Resting energy expenditure in human immunodeficiency virus-infected patients: comparison between patients with and without secondary infections. Am J Clin Nutr 1993; 57:614-9.
    • (1993) Am J Clin Nutr , vol.57 , pp. 614-619
    • Melchior, J.C.1    Raguin, G.2    Boulier, A.3
  • 10
    • 0028924390 scopus 로고
    • Wholebody protein turnover from leucine kinetics and the response to nutrition in human immunodeficiency virus infection
    • Macallan DC, McNurlan MA, Milne E, Calder AG, Garlick PJ, Griffin GE. Wholebody protein turnover from leucine kinetics and the response to nutrition in human immunodeficiency virus infection. Am J Clin Nutr 1995; 61:818-26.
    • (1995) Am J Clin Nutr , vol.61 , pp. 818-826
    • MacAllan, D.C.1    McNurlan, M.A.2    Milne, E.3    Calder, A.G.4    Garlick, P.J.5    Griffin, G.E.6
  • 11
    • 84930685126 scopus 로고    scopus 로고
    • Food and Agricultural Organzation of the United Nations Rome: FAO Accessed 25 July 2106
    • Food and Agricultural Organzation of the United Nations. The State of Food Insecurity in the World 2014. Rome: FAO, 2014. http://www.fao.org/publications/sofi/2014/en/. Accessed 25 July 2106.
    • (2014) The State of Food Insecurity in the World 2014
  • 12
    • 77949347626 scopus 로고    scopus 로고
    • Association between weight gain and clinical outcomes among malnourished adults initiating antiretroviral therapy in Lusaka, Zambia
    • Koethe JR, Lukusa A, Giganti MJ, et al. Association between weight gain and clinical outcomes among malnourished adults initiating antiretroviral therapy in Lusaka, Zambia. J Acquir Immune Defic Syndr 2010; 53:507-13.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 507-513
    • Koethe, J.R.1    Lukusa, A.2    Giganti, M.J.3
  • 13
    • 77955690397 scopus 로고    scopus 로고
    • Persistent microbial translocation and immune activation in HIV-1-infected South Africans receiving combination antiretroviral therapy
    • Cassol E, Malfeld S, Mahasha P, et al. Persistent microbial translocation and immune activation in HIV-1-infected South Africans receiving combination antiretroviral therapy. J Infect Dis 2010; 202:723-33.
    • (2010) J Infect Dis , vol.202 , pp. 723-733
    • Cassol, E.1    Malfeld, S.2    Mahasha, P.3
  • 14
    • 84964314815 scopus 로고    scopus 로고
    • A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy
    • Canipe A, Chidumayo T, Blevins M, et al. A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy. BMC Infect Dis 2014; 14:521.
    • (2014) BMC Infect Dis , vol.14 , pp. 521
    • Canipe, A.1    Chidumayo, T.2    Blevins, M.3
  • 15
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-71.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3
  • 16
    • 84861816724 scopus 로고    scopus 로고
    • Enteropathies in the developing world: Neglected effects on global health
    • Prendergast A, Kelly P. Enteropathies in the developing world: neglected effects on global health. Am J Trop Med Hyg 2012; 86:756-63.
    • (2012) Am J Trop Med Hyg , vol.86 , pp. 756-763
    • Prendergast, A.1    Kelly, P.2
  • 17
    • 85027956964 scopus 로고    scopus 로고
    • Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count
    • Marchetti G, Cozzi-Lepri A, Merlini E, et al. Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count. AIDS 2011; 25:1385-94.
    • (2011) AIDS , vol.25 , pp. 1385-1394
    • Marchetti, G.1    Cozzi-Lepri, A.2    Merlini, E.3
  • 18
    • 84937938856 scopus 로고    scopus 로고
    • Association of microbial translocation biomarkers with clinical outcome in controllers HIV-infected patients
    • Leon A, Leal L, Torres B, et al. Association of microbial translocation biomarkers with clinical outcome in controllers HIV-infected patients. AIDS 2015; 29:675-81.
    • (2015) AIDS , vol.29 , pp. 675-681
    • Leon, A.1    Leal, L.2    Torres, B.3
  • 19
    • 79952335046 scopus 로고    scopus 로고
    • Plasma levels of soluble CD14 independently predict mortality in HIV infection
    • Sandler NG,Wand H, Roque A, et al. Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis 2011; 203:780-90.
    • (2011) J Infect Dis , vol.203 , pp. 780-790
    • Sandler, N.G.1    Wand, H.2    Roque, A.3
  • 20
    • 84991015278 scopus 로고    scopus 로고
    • Pre-cART pro-inflammatory milieu, microbial translocation (MT) and risk of disease progression in HIV-infected patients starting their first cART: Data from the Icona Foundation Cohort
    • Barcelona, Spain 21-24 October
    • Marchetti G, Cozzi-Lepri A, Merlini E, et al. Pre-cART pro-inflammatory milieu, microbial translocation (MT) and risk of disease progression in HIV-infected patients starting their first cART: data from the Icona Foundation Cohort. Presented at: European AIDS Clinical Society, Barcelona, Spain, 21-24 October 2015.
    • (2015) European AIDS Clinical Society
    • Marchetti, G.1    Cozzi-Lepri, A.2    Merlini, E.3
  • 21
    • 53549129725 scopus 로고    scopus 로고
    • Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy
    • Marchetti G, Bellistri GM, Borghi E, et al. Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy. AIDS 2008; 22:2035-8.
    • (2008) AIDS , vol.22 , pp. 2035-2038
    • Marchetti, G.1    Bellistri, G.M.2    Borghi, E.3
  • 22
    • 0023258997 scopus 로고
    • Effect of total starvation and very low calorie diets on intestinal permeability in man
    • Elia M, Goren A, Behrens R, Barber RW, Neale G. Effect of total starvation and very low calorie diets on intestinal permeability in man. Clin Sci (Lond) 1987; 73:205-10.
    • (1987) Clin Sci (Lond) , vol.73 , pp. 205-210
    • Elia, M.1    Goren, A.2    Behrens, R.3    Barber, R.W.4    Neale, G.5
  • 23
    • 0031969046 scopus 로고    scopus 로고
    • Gut barrier function in malnourished patients
    • Welsh FK, Farmery SM, MacLennan K, et al. Gut barrier function in malnourished patients. Gut 1998; 42:396-401.
    • (1998) Gut , vol.42 , pp. 396-401
    • Welsh, F.K.1    Farmery, S.M.2    MacLennan, K.3
  • 24
    • 11144358077 scopus 로고    scopus 로고
    • Responses of small intestinal architecture and function over time to environmental factors in a tropical population
    • Kelly P, Menzies I, Crane R, et al. Responses of small intestinal architecture and function over time to environmental factors in a tropical population. Am J Trop Med Hyg 2004; 70:412-9.
    • (2004) Am J Trop Med Hyg , vol.70 , pp. 412-419
    • Kelly, P.1    Menzies, I.2    Crane, R.3
  • 26
    • 0141884335 scopus 로고    scopus 로고
    • Intestinal defensin gene expression in human populations
    • DhaliwalW, Bajaj-Elliott M, Kelly P. Intestinal defensin gene expression in human populations. Mol Immunol 2003; 40:469-75.
    • (2003) Mol Immunol , vol.40 , pp. 469-475
    • Dhaliwal, W.1    Bajaj-Elliott, M.2    Kelly, P.3
  • 27
    • 53449093632 scopus 로고    scopus 로고
    • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
    • Brenchley JM, Paiardini M, Knox KS, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 2008; 112:2826-35.
    • (2008) Blood , vol.112 , pp. 2826-2835
    • Brenchley, J.M.1    Paiardini, M.2    Knox, K.S.3
  • 28
    • 77954059792 scopus 로고    scopus 로고
    • Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation
    • Nazli A, Chan O, Dobson-Belaire WN, et al. Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation. PLoS Pathog 2010; 6:e1000852.
    • (2010) PLoS Pathog , vol.6 , pp. e1000852
    • Nazli, A.1    Chan, O.2    Dobson-Belaire, W.N.3
  • 29
    • 37349078686 scopus 로고    scopus 로고
    • Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration
    • Sankaran S, George MD, Reay E, et al. Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration. J Virol 2008; 82:538-45.
    • (2008) J Virol , vol.82 , pp. 538-545
    • Sankaran, S.1    George, M.D.2    Reay, E.3
  • 30
    • 0028879979 scopus 로고
    • Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea
    • Keating J, Bjarnason I, Somasundaram S, et al. Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea. Gut 1995; 37:623-9.
    • (1995) Gut , vol.37 , pp. 623-629
    • Keating, J.1    Bjarnason, I.2    Somasundaram, S.3
  • 31
    • 0025823029 scopus 로고
    • Altered small-intestinal permeability associated with diarrhoea in human-immunodeficiency-virus-infected Caucasian and African subjects
    • Kapembwa MS, Fleming SC, Sewankambo N, et al. Altered small-intestinal permeability associated with diarrhoea in human-immunodeficiency-virus-infected Caucasian and African subjects. Clin Sci (Lond) 1991; 81:327-34.
    • (1991) Clin Sci (Lond) , vol.81 , pp. 327-334
    • Kapembwa, M.S.1    Fleming, S.C.2    Sewankambo, N.3
  • 32
    • 84879520476 scopus 로고    scopus 로고
    • The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation
    • ChevalierMF, Petitjean G, Dunyach-Remy C, et al. The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation. PLoS Pathog 2013; 9:e1003453.
    • (2013) PLoS Pathog , vol.9 , pp. e1003453
    • Chevalier, M.F.1    Petitjean, G.2    Dunyach-Remy, C.3
  • 33
    • 78049291281 scopus 로고    scopus 로고
    • A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 infection
    • Smith AJ, Schacker TW, Reilly CS, Haase AT. A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 infection. J Acquir Immune Defic Syndr 2010; 55:306-15.
    • (2010) J Acquir Immune Defic Syndr , vol.55 , pp. 306-315
    • Smith, A.J.1    Schacker, T.W.2    Reilly, C.S.3    Haase, A.T.4
  • 34
    • 84936810525 scopus 로고    scopus 로고
    • Immunosuppressive tryptophan catabolism and gut mucosal dysfunction following early HIV infection
    • Jenabian MA, El-Far M, Vyboh K, et al. Immunosuppressive tryptophan catabolism and gut mucosal dysfunction following early HIV infection. J Infect Dis 2015; 212:355-66.
    • (2015) J Infect Dis , vol.212 , pp. 355-366
    • Jenabian, M.A.1    El-Far, M.2    Vyboh, K.3
  • 35
    • 0017341656 scopus 로고
    • Microbial ecology of the gastrointestinal tract
    • Savage DC. Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol 1977; 31:107-33.
    • (1977) Annu Rev Microbiol , vol.31 , pp. 107-133
    • Savage, D.C.1
  • 37
    • 84861980130 scopus 로고    scopus 로고
    • Interactions between the microbiota and the immune system
    • Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science 2012; 336:1268-73.
    • (2012) Science , vol.336 , pp. 1268-1273
    • Hooper, L.V.1    Littman, D.R.2    MacPherson, A.J.3
  • 39
    • 38949134533 scopus 로고    scopus 로고
    • Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis
    • Gori A, Tincati C, Rizzardini G, et al. Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis. J Clin Microbiol 2008; 46:757-8.
    • (2008) J Clin Microbiol , vol.46 , pp. 757-758
    • Gori, A.1    Tincati, C.2    Rizzardini, G.3
  • 40
    • 80051552856 scopus 로고    scopus 로고
    • Molecular characterization of stool microbiota in HIV-infected subjects by panbacterial and order-level 16S ribosomal DNA (rDNA) quantification and correlations with immune activation
    • Ellis CL, Ma ZM, Mann SK, et al. Molecular characterization of stool microbiota in HIV-infected subjects by panbacterial and order-level 16S ribosomal DNA (rDNA) quantification and correlations with immune activation. J Acquir Immune Defic Syndr 2011; 57:363-70.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 363-370
    • Ellis, C.L.1    Ma, Z.M.2    Mann, S.K.3
  • 41
    • 79954536349 scopus 로고    scopus 로고
    • Evidence for polymicrobic flora translocating in peripheral blood of HIV-infected patients with poor immune response to antiretroviral therapy
    • Merlini E, Bai F, Bellistri GM, Tincati C, d'Arminio Monforte A, Marchetti G. Evidence for polymicrobic flora translocating in peripheral blood of HIV-infected patients with poor immune response to antiretroviral therapy. PLoSOne 2011; 6:e18580.
    • (2011) PLoS One , vol.6 , pp. e18580
    • Merlini, E.1    Bai, F.2    Bellistri, G.M.3    Tincati, C.4    D'Arminio Monforte, A.5    Marchetti, G.6
  • 42
    • 84895733084 scopus 로고    scopus 로고
    • A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects
    • Mutlu EA, Keshavarzian A, Losurdo J, et al. A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. PLoS Pathog 2014; 10:e1003829.
    • (2014) PLoS Pathog , vol.10 , pp. e1003829
    • Mutlu, E.A.1    Keshavarzian, A.2    Losurdo, J.3
  • 43
    • 84926519274 scopus 로고    scopus 로고
    • HIV-associated mucosal gene expression: Region-specific alterations
    • Voigt RM, Keshavarzian A, Losurdo J, et al. HIV-associated mucosal gene expression: region-specific alterations. AIDS 2015; 29:537-46.
    • (2015) AIDS , vol.29 , pp. 537-546
    • Voigt, R.M.1    Keshavarzian, A.2    Losurdo, J.3
  • 44
    • 84880540665 scopus 로고    scopus 로고
    • Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism
    • Vujkovic-Cvijin I, Dunham RM, Iwai S, et al. Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism. Sci Transl Med 2013; 5:193ra91.
    • (2013) Sci Transl Med , vol.5 , pp. 193ra91
    • Vujkovic-Cvijin, I.1    Dunham, R.M.2    Iwai, S.3
  • 45
    • 84900493012 scopus 로고    scopus 로고
    • An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia
    • Dillon SM, Lee EJ, Kotter CV, et al. An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. Mucosal Immunol 2014; 7:983-94.
    • (2014) Mucosal Immunol , vol.7 , pp. 983-994
    • Dillon, S.M.1    Lee, E.J.2    Kotter, C.V.3
  • 46
    • 84884379881 scopus 로고    scopus 로고
    • Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection
    • Perez-Santiago J, Gianella S, Massanella M, et al. Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. AIDS 2013; 27:1921-31.
    • (2013) AIDS , vol.27 , pp. 1921-1931
    • Perez-Santiago, J.1    Gianella, S.2    Massanella, M.3
  • 47
    • 84922414182 scopus 로고    scopus 로고
    • Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection
    • Dinh DM, Volpe GE, Duffalo C, et al. Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection. J Infect Dis 2015; 211:19-27.
    • (2015) J Infect Dis , vol.211 , pp. 19-27
    • Dinh, D.M.1    Volpe, G.E.2    Duffalo, C.3
  • 48
    • 0343012289 scopus 로고
    • Changes in intestinal bacterial flora and role of infection in Kwashiorkor
    • Smythe PM. Changes in intestinal bacterial flora and role of infection in Kwashiorkor. Lancet 1958; 2:724-7.
    • (1958) Lancet , vol.2 , pp. 724-727
    • Smythe, P.M.1
  • 49
    • 84862679988 scopus 로고    scopus 로고
    • Gut microbiota of healthy and malnourished children in Bangladesh
    • Monira S, Nakamura S, Gotoh K, et al. Gut microbiota of healthy and malnourished children in bangladesh. Front Microbiol 2011; 2:228.
    • (2011) Front Microbiol , vol.2 , pp. 228
    • Monira, S.1    Nakamura, S.2    Gotoh, K.3
  • 50
    • 84899752631 scopus 로고    scopus 로고
    • Gut microbiomes of Indian children of varying nutritional status
    • 51-168. These references are available in the Supplementary Appendix
    • Ghosh TS, Gupta SS, Bhattacharya T, et al. Gut microbiomes of Indian children of varying nutritional status. PLoS One 2014; 9:e95547. 51-168. These references are available in the Supplementary Appendix.
    • (2014) PLoS One , vol.9 , pp. e95547
    • Ghosh, T.S.1    Gupta, S.S.2    Bhattacharya, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.