-
2
-
-
84858124845
-
Generation and physiological roles of linear ubiquitin chains
-
Walczak H, Iwai K, Dikic I (2012) Generation and physiological roles of linear ubiquitin chains. BMC Biol 10: 23
-
(2012)
BMC Biol
, vol.10
, pp. 23
-
-
Walczak, H.1
Iwai, K.2
Dikic, I.3
-
3
-
-
84931055813
-
Linear ubiquitination signals in adaptive immune responses
-
Ikeda F (2015) Linear ubiquitination signals in adaptive immune responses. Immunol Rev 266: 222–236
-
(2015)
Immunol Rev
, vol.266
, pp. 222-236
-
-
Ikeda, F.1
-
4
-
-
84931031608
-
Roles of linear ubiquitinylation, a crucial regulator of NF-kappaB and cell death, in the immune system
-
Sasaki K, Iwai K (2015) Roles of linear ubiquitinylation, a crucial regulator of NF-kappaB and cell death, in the immune system. Immunol Rev 266: 175–189
-
(2015)
Immunol Rev
, vol.266
, pp. 175-189
-
-
Sasaki, K.1
Iwai, K.2
-
5
-
-
84912041074
-
Met1-linked ubiquitination in immune signalling
-
Fiil BK, Gyrd-Hansen M (2014) Met1-linked ubiquitination in immune signalling. FEBS J 281: 4337–4350
-
(2014)
FEBS J
, vol.281
, pp. 4337-4350
-
-
Fiil, B.K.1
Gyrd-Hansen, M.2
-
6
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako T, Kamei K, Murata S, Kato M, Fukumoto H, Kanie M, Sano S, Tokunaga F, Tanaka K, Iwai K (2006) A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J 25: 4877–4887
-
(2006)
EMBO J
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
Kamei, K.2
Murata, S.3
Kato, M.4
Fukumoto, H.5
Kanie, M.6
Sano, S.7
Tokunaga, F.8
Tanaka, K.9
Iwai, K.10
-
7
-
-
79953237668
-
SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex
-
Tokunaga F, Nakagawa T, Nakahara M, Saeki Y, Taniguchi M, Sakata S, Tanaka K, Nakano H, Iwai K (2011) SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex. Nature 471: 633–636
-
(2011)
Nature
, vol.471
, pp. 633-636
-
-
Tokunaga, F.1
Nakagawa, T.2
Nakahara, M.3
Saeki, Y.4
Taniguchi, M.5
Sakata, S.6
Tanaka, K.7
Nakano, H.8
Iwai, K.9
-
8
-
-
79953239980
-
SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis
-
Ikeda F, Deribe YL, Skanland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J et al (2011) SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis. Nature 471: 637–641
-
(2011)
Nature
, vol.471
, pp. 637-641
-
-
Ikeda, F.1
Deribe, Y.L.2
Skanland, S.S.3
Stieglitz, B.4
Grabbe, C.5
Franz-Wachtel, M.6
van Wijk, S.J.7
Goswami, P.8
Nagy, V.9
Terzic, J.10
-
9
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B, Cordier SM, Schmukle AC, Emmerich CH, Rieser E, Haas TL, Webb AI, Rickard JA, Anderton H, Wong WW et al (2011) Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471: 591–596
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
-
10
-
-
84867096523
-
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
-
Smit JJ, Monteferrario D, Noordermeer SM, van Dijk WJ, van der Reijden BA, Sixma TK (2012) The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J 31: 3833–3844
-
(2012)
EMBO J
, vol.31
, pp. 3833-3844
-
-
Smit, J.J.1
Monteferrario, D.2
Noordermeer, S.M.3
van Dijk, W.J.4
van der Reijden, B.A.5
Sixma, T.K.6
-
11
-
-
84888034624
-
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
-
Stieglitz B, Rana RR, Koliopoulos MG, Morris-Davies AC, Schaeffer V, Christodoulou E, Howell S, Brown NR, Dikic I, Rittinger K (2013) Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature 503: 422–426
-
(2013)
Nature
, vol.503
, pp. 422-426
-
-
Stieglitz, B.1
Rana, R.R.2
Koliopoulos, M.G.3
Morris-Davies, A.C.4
Schaeffer, V.5
Christodoulou, E.6
Howell, S.7
Brown, N.R.8
Dikic, I.9
Rittinger, K.10
-
12
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T et al (2009) Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell 36: 831–844
-
(2009)
Mol Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
13
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S et al (2009) Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol 11: 123–132
-
(2009)
Nat Cell Biol
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
Kamei, K.6
Nakagawa, T.7
Kato, M.8
Murata, S.9
Yamaoka, S.10
-
14
-
-
84907995994
-
HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death
-
Peltzer N, Rieser E, Taraborrelli L, Draber P, Darding M, Pernaute B, Shimizu Y, Sarr A, Draberova H, Montinaro A et al (2014) HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death. Cell Rep 9: 153–165
-
(2014)
Cell Rep
, vol.9
, pp. 153-165
-
-
Peltzer, N.1
Rieser, E.2
Taraborrelli, L.3
Draber, P.4
Darding, M.5
Pernaute, B.6
Shimizu, Y.7
Sarr, A.8
Draberova, H.9
Montinaro, A.10
-
15
-
-
84924401688
-
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
-
Kumari S, Redouane Y, Lopez-Mosqueda J, Shiraishi R, Romanowska M, Lutzmayer S, Kuiper J, Martinez C, Dikic I, Pasparakis M et al (2014) Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis. eLife 3: e03422
-
(2014)
eLife
, vol.3
-
-
Kumari, S.1
Redouane, Y.2
Lopez-Mosqueda, J.3
Shiraishi, R.4
Romanowska, M.5
Lutzmayer, S.6
Kuiper, J.7
Martinez, C.8
Dikic, I.9
Pasparakis, M.10
-
16
-
-
84863000898
-
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity
-
Damgaard RB, Nachbur U, Yabal M, Wong WW, Fiil BK, Kastirr M, Rieser E, Rickard JA, Bankovacki A, Peschel C et al (2012) The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Mol Cell 46: 746–758
-
(2012)
Mol Cell
, vol.46
, pp. 746-758
-
-
Damgaard, R.B.1
Nachbur, U.2
Yabal, M.3
Wong, W.W.4
Fiil, B.K.5
Kastirr, M.6
Rieser, E.7
Rickard, J.A.8
Bankovacki, A.9
Peschel, C.10
-
17
-
-
84884345970
-
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
-
Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, Komander D, Cohen P (2013) Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proc Natl Acad Sci USA 110: 15247–15252
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 15247-15252
-
-
Emmerich, C.H.1
Ordureau, A.2
Strickson, S.3
Arthur, J.S.4
Pedrioli, P.G.5
Komander, D.6
Cohen, P.7
-
18
-
-
84878862687
-
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin
-
Keusekotten K, Elliott PR, Glockner L, Fiil BK, Damgaard RB, Kulathu Y, Wauer T, Hospenthal MK, Gyrd-Hansen M, Krappmann D et al (2013) OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin. Cell 153: 1312–1326
-
(2013)
Cell
, vol.153
, pp. 1312-1326
-
-
Keusekotten, K.1
Elliott, P.R.2
Glockner, L.3
Fiil, B.K.4
Damgaard, R.B.5
Kulathu, Y.6
Wauer, T.7
Hospenthal, M.K.8
Gyrd-Hansen, M.9
Krappmann, D.10
-
19
-
-
84899911195
-
Molecular basis and regulation of OTULIN-LUBAC interaction
-
Elliott PR, Nielsen SV, Marco-Casanova P, Fiil BK, Keusekotten K, Mailand N, Freund SM, Gyrd-Hansen M, Komander D (2014) Molecular basis and regulation of OTULIN-LUBAC interaction. Mol Cell 54: 335–348
-
(2014)
Mol Cell
, vol.54
, pp. 335-348
-
-
Elliott, P.R.1
Nielsen, S.V.2
Marco-Casanova, P.3
Fiil, B.K.4
Keusekotten, K.5
Mailand, N.6
Freund, S.M.7
Gyrd-Hansen, M.8
Komander, D.9
-
20
-
-
84899982792
-
Binding of OTULIN to the PUB domain of HOIP controls NF-kappaB signaling
-
Schaeffer V, Akutsu M, Olma MH, Gomes LC, Kawasaki M, Dikic I (2014) Binding of OTULIN to the PUB domain of HOIP controls NF-kappaB signaling. Mol Cell 54: 349–361
-
(2014)
Mol Cell
, vol.54
, pp. 349-361
-
-
Schaeffer, V.1
Akutsu, M.2
Olma, M.H.3
Gomes, L.C.4
Kawasaki, M.5
Dikic, I.6
-
21
-
-
84894496869
-
Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN
-
Takiuchi T, Nakagawa T, Tamiya H, Fujita H, Sasaki Y, Saeki Y, Takeda H, Sawasaki T, Buchberger A, Kimura T et al (2014) Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN. Genes Cells 19: 254–272
-
(2014)
Genes Cells
, vol.19
, pp. 254-272
-
-
Takiuchi, T.1
Nakagawa, T.2
Tamiya, H.3
Fujita, H.4
Sasaki, Y.5
Saeki, Y.6
Takeda, H.7
Sawasaki, T.8
Buchberger, A.9
Kimura, T.10
-
22
-
-
84968887534
-
LUBAC-recruited CYLD and A20 regulate gene activation and cell death by exerting opposing effects on linear ubiquitin in signaling complexes
-
Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T et al (2015) LUBAC-recruited CYLD and A20 regulate gene activation and cell death by exerting opposing effects on linear ubiquitin in signaling complexes. Cell Rep 13: 2258–2272
-
(2015)
Cell Rep
, vol.13
, pp. 2258-2272
-
-
Draber, P.1
Kupka, S.2
Reichert, M.3
Draberova, H.4
Lafont, E.5
de Miguel, D.6
Spilgies, L.7
Surinova, S.8
Taraborrelli, L.9
Hartwig, T.10
-
23
-
-
84858725584
-
Regulation of NF-kappaB by deubiquitinases
-
Harhaj EW, Dixit VM (2012) Regulation of NF-kappaB by deubiquitinases. Immunol Rev 246: 107–124
-
(2012)
Immunol Rev
, vol.246
, pp. 107-124
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
24
-
-
84860478940
-
A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex
-
Yagi H, Ishimoto K, Hiromoto T, Fujita H, Mizushima T, Uekusa Y, Yagi-Utsumi M, Kurimoto E, Noda M, Uchiyama S et al (2012) A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex. EMBO Rep 13: 462–468
-
(2012)
EMBO Rep
, vol.13
, pp. 462-468
-
-
Yagi, H.1
Ishimoto, K.2
Hiromoto, T.3
Fujita, H.4
Mizushima, T.5
Uekusa, Y.6
Yagi-Utsumi, M.7
Kurimoto, E.8
Noda, M.9
Uchiyama, S.10
-
25
-
-
67449091213
-
What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor?
-
Michelle C, Vourc'h P, Mignon L, Andres CR (2009) What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor? J Mol Evol 68: 616–628
-
(2009)
J Mol Evol
, vol.68
, pp. 616-628
-
-
Michelle, C.1
Vourc'h, P.2
Mignon, L.3
Andres, C.R.4
-
26
-
-
84867062977
-
A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7
-
Verhelst K, Carpentier I, Kreike M, Meloni L, Verstrepen L, Kensche T, Dikic I, Beyaert R (2012) A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7. EMBO J 31: 3845–3855
-
(2012)
EMBO J
, vol.31
, pp. 3845-3855
-
-
Verhelst, K.1
Carpentier, I.2
Kreike, M.3
Meloni, L.4
Verstrepen, L.5
Kensche, T.6
Dikic, I.7
Beyaert, R.8
-
27
-
-
84879390723
-
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
-
Rivkin E, Almeida SM, Ceccarelli DF, Juang YC, MacLean TA, Srikumar T, Huang H, Dunham WH, Fukumura R, Xie G et al (2013) The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature 498: 318–324
-
(2013)
Nature
, vol.498
, pp. 318-324
-
-
Rivkin, E.1
Almeida, S.M.2
Ceccarelli, D.F.3
Juang, Y.C.4
MacLean, T.A.5
Srikumar, T.6
Huang, H.7
Dunham, W.H.8
Fukumura, R.9
Xie, G.10
-
28
-
-
79952301200
-
Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains
-
Akutsu M, Ye Y, Virdee S, Chin JW, Komander D (2011) Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc Natl Acad Sci USA 108: 2228–2233
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2228-2233
-
-
Akutsu, M.1
Ye, Y.2
Virdee, S.3
Chin, J.W.4
Komander, D.5
-
29
-
-
79957949190
-
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
-
Wenzel DM, Lissounov A, Brzovic PS, Klevit RE (2011) UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature 474: 105–108
-
(2011)
Nature
, vol.474
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
30
-
-
84865709638
-
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
-
Stieglitz B, Morris-Davies AC, Koliopoulos MG, Christodoulou E, Rittinger K (2012) LUBAC synthesizes linear ubiquitin chains via a thioester intermediate. EMBO Rep 13: 840–846
-
(2012)
EMBO Rep
, vol.13
, pp. 840-846
-
-
Stieglitz, B.1
Morris-Davies, A.C.2
Koliopoulos, M.G.3
Christodoulou, E.4
Rittinger, K.5
-
31
-
-
70449084692
-
Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities
-
Hjerpe R, Aillet F, Lopitz-Otsoa F, Lang V, England P, Rodriguez MS (2009) Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities. EMBO Rep 10: 1250–1258
-
(2009)
EMBO Rep
, vol.10
, pp. 1250-1258
-
-
Hjerpe, R.1
Aillet, F.2
Lopitz-Otsoa, F.3
Lang, V.4
England, P.5
Rodriguez, M.S.6
-
32
-
-
84861344026
-
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs)
-
Lopitz-Otsoa F, Rodriguez-Suarez E, Aillet F, Casado-Vela J, Lang V, Matthiesen R, Elortza F, Rodriguez MS (2012) Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). J Proteomics 75: 2998–3014
-
(2012)
J Proteomics
, vol.75
, pp. 2998-3014
-
-
Lopitz-Otsoa, F.1
Rodriguez-Suarez, E.2
Aillet, F.3
Casado-Vela, J.4
Lang, V.5
Matthiesen, R.6
Elortza, F.7
Rodriguez, M.S.8
-
33
-
-
44649166613
-
Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins
-
Wagner S, Carpentier I, Rogov V, Kreike M, Ikeda F, Lohr F, Wu CJ, Ashwell JD, Dotsch V, Dikic I et al (2008) Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. Oncogene 27: 3739–3745
-
(2008)
Oncogene
, vol.27
, pp. 3739-3745
-
-
Wagner, S.1
Carpentier, I.2
Rogov, V.3
Kreike, M.4
Ikeda, F.5
Lohr, F.6
Wu, C.J.7
Ashwell, J.D.8
Dotsch, V.9
Dikic, I.10
-
34
-
-
67349231313
-
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
-
Komander D, Reyes-Turcu F, Licchesi JD, Odenwaelder P, Wilkinson KD, Barford D (2009) Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains. EMBO Rep 10: 466–473
-
(2009)
EMBO Rep
, vol.10
, pp. 466-473
-
-
Komander, D.1
Reyes-Turcu, F.2
Licchesi, J.D.3
Odenwaelder, P.4
Wilkinson, K.D.5
Barford, D.6
-
35
-
-
34547754626
-
A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense
-
Tsichritzis T, Gaentzsch PC, Kosmidis S, Brown AE, Skoulakis EM, Ligoxygakis P, Mosialos G (2007) A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense. Development 134: 2605–2614
-
(2007)
Development
, vol.134
, pp. 2605-2614
-
-
Tsichritzis, T.1
Gaentzsch, P.C.2
Kosmidis, S.3
Brown, A.E.4
Skoulakis, E.M.5
Ligoxygakis, P.6
Mosialos, G.7
-
36
-
-
84984904321
-
SPATA2 links CYLD to the TNF-alpha receptor signaling complex and modulates the receptor signaling outcomes
-
Wagner SA, Satpathy S, Beli P, Choudhary C (2016) SPATA2 links CYLD to the TNF-alpha receptor signaling complex and modulates the receptor signaling outcomes. EMBO J 35: 1868–1884
-
(2016)
EMBO J
, vol.35
, pp. 1868-1884
-
-
Wagner, S.A.1
Satpathy, S.2
Beli, P.3
Choudhary, C.4
-
37
-
-
84890492742
-
Spatial expression of transcription factors in Drosophila embryonic organ development
-
Hammonds AS, Bristow CA, Fisher WW, Weiszmann R, Wu S, Hartenstein V, Kellis M, Yu B, Frise E, Celniker SE (2013) Spatial expression of transcription factors in Drosophila embryonic organ development. Genome Biol 14: R140
-
(2013)
Genome Biol
, vol.14
, pp. R140
-
-
Hammonds, A.S.1
Bristow, C.A.2
Fisher, W.W.3
Weiszmann, R.4
Wu, S.5
Hartenstein, V.6
Kellis, M.7
Yu, B.8
Frise, E.9
Celniker, S.E.10
-
38
-
-
38349127974
-
Global analysis of patterns of gene expression during Drosophila embryogenesis
-
Tomancak P, Berman BP, Beaton A, Weiszmann R, Kwan E, Hartenstein V, Celniker SE, Rubin GM (2007) Global analysis of patterns of gene expression during Drosophila embryogenesis. Genome Biol 8: R145
-
(2007)
Genome Biol
, vol.8
, pp. R145
-
-
Tomancak, P.1
Berman, B.P.2
Beaton, A.3
Weiszmann, R.4
Kwan, E.5
Hartenstein, V.6
Celniker, S.E.7
Rubin, G.M.8
-
39
-
-
0012252471
-
Systematic determination of patterns of gene expression during Drosophila embryogenesis
-
research0088
-
Tomancak P, Beaton A, Weiszmann R, Kwan E, Shu S, Lewis SE, Richards S, Ashburner M, Hartenstein V, Celniker SE et al (2002) Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol 3: research0088
-
(2002)
Genome Biol
, vol.3
-
-
Tomancak, P.1
Beaton, A.2
Weiszmann, R.3
Kwan, E.4
Shu, S.5
Lewis, S.E.6
Richards, S.7
Ashburner, M.8
Hartenstein, V.9
Celniker, S.E.10
-
40
-
-
0033231556
-
Relish, a central factor in the control of humoral but not cellular immunity in Drosophila
-
Hedengren M, Asling B, Dushay MS, Ando I, Ekengren S, Wihlborg M, Hultmark D (1999) Relish, a central factor in the control of humoral but not cellular immunity in Drosophila. Mol Cell 4: 827–837
-
(1999)
Mol Cell
, vol.4
, pp. 827-837
-
-
Hedengren, M.1
Asling, B.2
Dushay, M.S.3
Ando, I.4
Ekengren, S.5
Wihlborg, M.6
Hultmark, D.7
-
41
-
-
84925285850
-
Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress
-
Fang NN, Chan GT, Zhu M, Comyn SA, Persaud A, Deshaies RJ, Rotin D, Gsponer J, Mayor T (2014) Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress. Nat Cell Biol 16: 1227–1237
-
(2014)
Nat Cell Biol
, vol.16
, pp. 1227-1237
-
-
Fang, N.N.1
Chan, G.T.2
Zhu, M.3
Comyn, S.A.4
Persaud, A.5
Deshaies, R.J.6
Rotin, D.7
Gsponer, J.8
Mayor, T.9
-
42
-
-
0031447741
-
Myocyte enhancer factor 2 (MEF2)
-
Brand NJ (1997) Myocyte enhancer factor 2 (MEF2). Int J Biochem Cell Biol 29: 1467–1470
-
(1997)
Int J Biochem Cell Biol
, vol.29
, pp. 1467-1470
-
-
Brand, N.J.1
-
43
-
-
0032437107
-
Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
-
Black BL, Olson EN (1998) Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol 14: 167–196
-
(1998)
Annu Rev Cell Dev Biol
, vol.14
, pp. 167-196
-
-
Black, B.L.1
Olson, E.N.2
-
44
-
-
85011940601
-
The evolutionarily conserved RNA binding protein SMOOTH is essential for maintaining normal muscle function
-
Draper I, Tabaka ME, Jackson FR, Salomon RN, Kopin AS (2009) The evolutionarily conserved RNA binding protein SMOOTH is essential for maintaining normal muscle function. Fly 3: 235–246
-
(2009)
Fly
, vol.3
, pp. 235-246
-
-
Draper, I.1
Tabaka, M.E.2
Jackson, F.R.3
Salomon, R.N.4
Kopin, A.S.5
-
45
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401–415
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
46
-
-
77954955686
-
Heat shock factors: integrators of cell stress, development and lifespan
-
Akerfelt M, Morimoto RI, Sistonen L (2010) Heat shock factors: integrators of cell stress, development and lifespan. Nat Rev Mol Cell Biol 11: 545–555
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 545-555
-
-
Akerfelt, M.1
Morimoto, R.I.2
Sistonen, L.3
-
47
-
-
84929944191
-
Fever and the thermal regulation of immunity: the immune system feels the heat
-
Evans SS, Repasky EA, Fisher DT (2015) Fever and the thermal regulation of immunity: the immune system feels the heat. Nat Rev Immunol 15: 335–349
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 335-349
-
-
Evans, S.S.1
Repasky, E.A.2
Fisher, D.T.3
-
48
-
-
84980347632
-
Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia
-
Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov HG, Hopkins G, Du L, Belkadi A et al (2015) Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia. J Exp Med 212: 939–951
-
(2015)
J Exp Med
, vol.212
, pp. 939-951
-
-
Boisson, B.1
Laplantine, E.2
Dobbs, K.3
Cobat, A.4
Tarantino, N.5
Hazen, M.6
Lidov, H.G.7
Hopkins, G.8
Du, L.9
Belkadi, A.10
-
49
-
-
84880934152
-
Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement
-
Wang K, Kim C, Bradfield J, Guo Y, Toskala E, Otieno FG, Hou C, Thomas K, Cardinale C, Lyon GJ et al (2013) Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement. Genome Med 5: 67
-
(2013)
Genome Med
, vol.5
, pp. 67
-
-
Wang, K.1
Kim, C.2
Bradfield, J.3
Guo, Y.4
Toskala, E.5
Otieno, F.G.6
Hou, C.7
Thomas, K.8
Cardinale, C.9
Lyon, G.J.10
-
50
-
-
84883768942
-
Polyglucosan body myopathy caused by defective ubiquitin ligase RBCK1
-
Nilsson J, Schoser B, Laforet P, Kalev O, Lindberg C, Romero NB, Davila Lopez M, Akman HO, Wahbi K, Iglseder S et al (2013) Polyglucosan body myopathy caused by defective ubiquitin ligase RBCK1. Ann Neurol 74: 914–919
-
(2013)
Ann Neurol
, vol.74
, pp. 914-919
-
-
Nilsson, J.1
Schoser, B.2
Laforet, P.3
Kalev, O.4
Lindberg, C.5
Romero, N.B.6
Davila Lopez, M.7
Akman, H.O.8
Wahbi, K.9
Iglseder, S.10
-
51
-
-
84931058612
-
The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination
-
Elton L, Carpentier I, Verhelst K, Staal J, Beyaert R (2015) The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination. Immunol Rev 266: 208–221
-
(2015)
Immunol Rev
, vol.266
, pp. 208-221
-
-
Elton, L.1
Carpentier, I.2
Verhelst, K.3
Staal, J.4
Beyaert, R.5
-
52
-
-
0037396011
-
Tamo selectively modulates nuclear import in Drosophila
-
Minakhina S, Yang J, Steward R (2003) Tamo selectively modulates nuclear import in Drosophila. Genes Cells 8: 299–310
-
(2003)
Genes Cells
, vol.8
, pp. 299-310
-
-
Minakhina, S.1
Yang, J.2
Steward, R.3
-
53
-
-
0034569782
-
Regulation of dorso/ventral patterning in the Drosophila embryo by multiple dorsal-interacting proteins
-
Flores-Saaib RD, Courey AJ (2000) Regulation of dorso/ventral patterning in the Drosophila embryo by multiple dorsal-interacting proteins. Cell Biochem Biophys 33: 1–17
-
(2000)
Cell Biochem Biophys
, vol.33
, pp. 1-17
-
-
Flores-Saaib, R.D.1
Courey, A.J.2
-
54
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
-
Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R, Kensche T, Uejima T, Bloor S, Komander D et al (2009) Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell 136: 1098–1109
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
Akutsu, M.4
Suzuki, N.5
Kato, R.6
Kensche, T.7
Uejima, T.8
Bloor, S.9
Komander, D.10
-
55
-
-
84855517985
-
Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
-
Sato Y, Fujita H, Yoshikawa A, Yamashita M, Yamagata A, Kaiser SE, Iwai K, Fukai S (2011) Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex. Proc Natl Acad Sci USA 108: 20520–20525
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20520-20525
-
-
Sato, Y.1
Fujita, H.2
Yoshikawa, A.3
Yamashita, M.4
Yamagata, A.5
Kaiser, S.E.6
Iwai, K.7
Fukai, S.8
-
56
-
-
84867043680
-
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
-
Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O (2012) Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation. EMBO J 31: 3856–3870
-
(2012)
EMBO J
, vol.31
, pp. 3856-3870
-
-
Tokunaga, F.1
Nishimasu, H.2
Ishitani, R.3
Goto, E.4
Noguchi, T.5
Mio, K.6
Kamei, K.7
Ma, A.8
Iwai, K.9
Nureki, O.10
-
57
-
-
26644432726
-
The role of ubiquitination in Drosophila innate immunity
-
Zhou R, Silverman N, Hong M, Liao DS, Chung Y, Chen ZJ, Maniatis T (2005) The role of ubiquitination in Drosophila innate immunity. J Biol Chem 280: 34048–34055
-
(2005)
J Biol Chem
, vol.280
, pp. 34048-34055
-
-
Zhou, R.1
Silverman, N.2
Hong, M.3
Liao, D.S.4
Chung, Y.5
Chen, Z.J.6
Maniatis, T.7
-
58
-
-
0034303573
-
Role of Drosophila IKK gamma in a toll-independent antibacterial immune response
-
Rutschmann S, Jung AC, Zhou R, Silverman N, Hoffmann JA, Ferrandon D (2000) Role of Drosophila IKK gamma in a toll-independent antibacterial immune response. Nat Immunol 1: 342–347
-
(2000)
Nat Immunol
, vol.1
, pp. 342-347
-
-
Rutschmann, S.1
Jung, A.C.2
Zhou, R.3
Silverman, N.4
Hoffmann, J.A.5
Ferrandon, D.6
-
59
-
-
84922481687
-
Immunity in Drosophila melanogaster–from microbial recognition to whole-organism physiology
-
Buchon N, Silverman N, Cherry S (2014) Immunity in Drosophila melanogaster–from microbial recognition to whole-organism physiology. Nat Rev Immunol 14: 796–810
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 796-810
-
-
Buchon, N.1
Silverman, N.2
Cherry, S.3
-
60
-
-
84928139542
-
A comprehensive method for detecting ubiquitinated substrates using TR-TUBE
-
Yoshida Y, Saeki Y, Murakami A, Kawawaki J, Tsuchiya H, Yoshihara H, Shindo M, Tanaka K (2015) A comprehensive method for detecting ubiquitinated substrates using TR-TUBE. Proc Natl Acad Sci USA 112: 4630–4635
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 4630-4635
-
-
Yoshida, Y.1
Saeki, Y.2
Murakami, A.3
Kawawaki, J.4
Tsuchiya, H.5
Yoshihara, H.6
Shindo, M.7
Tanaka, K.8
-
61
-
-
84925949741
-
Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)
-
Hospenthal MK, Mevissen TE, Komander D (2015) Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest). Nat Protoc 10: 349–361
-
(2015)
Nat Protoc
, vol.10
, pp. 349-361
-
-
Hospenthal, M.K.1
Mevissen, T.E.2
Komander, D.3
-
62
-
-
82755182013
-
Universal and confident phosphorylation site localization using phosphoRS
-
Taus T, Kocher T, Pichler P, Paschke C, Schmidt A, Henrich C, Mechtler K (2011) Universal and confident phosphorylation site localization using phosphoRS. J Proteome Res 10: 5354–5362
-
(2011)
J Proteome Res
, vol.10
, pp. 5354-5362
-
-
Taus, T.1
Kocher, T.2
Pichler, P.3
Paschke, C.4
Schmidt, A.5
Henrich, C.6
Mechtler, K.7
-
63
-
-
34447530305
-
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
-
Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, Fellner M, Gasser B, Kinsey K, Oppel S, Scheiblauer S et al (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448: 151–156
-
(2007)
Nature
, vol.448
, pp. 151-156
-
-
Dietzl, G.1
Chen, D.2
Schnorrer, F.3
Su, K.C.4
Barinova, Y.5
Fellner, M.6
Gasser, B.7
Kinsey, K.8
Oppel, S.9
Scheiblauer, S.10
-
64
-
-
84910658482
-
Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila
-
Gokcezade J, Sienski G, Duchek P (2014) Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila. G3 4: 2279–2282
-
(2014)
G3
, vol.4
, pp. 2279-2282
-
-
Gokcezade, J.1
Sienski, G.2
Duchek, P.3
-
65
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
-
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389–3402
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
66
-
-
45949107473
-
Recent developments in the MAFFT multiple sequence alignment program
-
Katoh K, Toh H (2008) Recent developments in the MAFFT multiple sequence alignment program. Brief Bioinform 9: 286–298
-
(2008)
Brief Bioinform
, vol.9
, pp. 286-298
-
-
Katoh, K.1
Toh, H.2
-
67
-
-
84871809302
-
STAR: ultrafast universal RNA-seq aligner
-
Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29: 15–21
-
(2013)
Bioinformatics
, vol.29
, pp. 15-21
-
-
Dobin, A.1
Davis, C.A.2
Schlesinger, F.3
Drenkow, J.4
Zaleski, C.5
Jha, S.6
Batut, P.7
Chaisson, M.8
Gingeras, T.R.9
-
68
-
-
84876996918
-
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
-
Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL (2013) TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 14: R36
-
(2013)
Genome Biol
, vol.14
, pp. R36
-
-
Kim, D.1
Pertea, G.2
Trapnell, C.3
Pimentel, H.4
Kelley, R.5
Salzberg, S.L.6
-
69
-
-
84928987900
-
HTSeq–a Python framework to work with high-throughput sequencing data
-
Anders S, Pyl PT, Huber W (2015) HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics 31: 166–169
-
(2015)
Bioinformatics
, vol.31
, pp. 166-169
-
-
Anders, S.1
Pyl, P.T.2
Huber, W.3
-
70
-
-
78651271733
-
Integrative genomics viewer
-
Robinson JT, Thorvaldsdottir H, Winckler W, Guttman M, Lander ES, Getz G, Mesirov JP (2011) Integrative genomics viewer. Nat Biotechnol 29: 24–26
-
(2011)
Nat Biotechnol
, vol.29
, pp. 24-26
-
-
Robinson, J.T.1
Thorvaldsdottir, H.2
Winckler, W.3
Guttman, M.4
Lander, E.S.5
Getz, G.6
Mesirov, J.P.7
-
71
-
-
84875634162
-
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration
-
Thorvaldsdottir H, Robinson JT, Mesirov JP (2013) Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform 14: 178–192
-
(2013)
Brief Bioinform
, vol.14
, pp. 178-192
-
-
Thorvaldsdottir, H.1
Robinson, J.T.2
Mesirov, J.P.3
-
72
-
-
45549104911
-
Drosophila immunity: methods for monitoring the activity of Toll and Imd signaling pathways
-
Romeo Y, Lemaitre B (2008) Drosophila immunity: methods for monitoring the activity of Toll and Imd signaling pathways. Methods Mol Biol 415: 379–394
-
(2008)
Methods Mol Biol
, vol.415
, pp. 379-394
-
-
Romeo, Y.1
Lemaitre, B.2
|