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Volumn 9, Issue SEP2016, 2016, Pages

“Soldiers heart”: A genetic basis for elevated cardiovascular disease risk associated with post-traumatic stress disorder

Author keywords

Candidate gene; Cardiovascular disease; Post traumatic stress disorder; Type 2 diabetes mellitus

Indexed keywords

ADENYLATE CYCLASE; CATECHOL METHYLTRANSFERASE INHIBITOR; CRYOPYRIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; DOPAMINE TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 3; FK 506 BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; GLUCOCORTICOID RECEPTOR; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPIC AGENT; PROTEIN KINASE B; PROTEIN KINASE C; RGS2 PROTEIN; SEROTONIN; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 2; TUMOR NECROSIS FACTOR;

EID: 84989903975     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2016.00087     Document Type: Article
Times cited : (29)

References (66)
  • 2
    • 84963625871 scopus 로고    scopus 로고
    • PTSD and risk of incident cardiovascular disease in aging veterans
    • Beristianos, M. H., Yaffe, K., Cohen, B., and Byers, A. L. (2014). PTSD and risk of incident cardiovascular disease in aging veterans. Am. J. Geriatr. Psychiatry 24, 192-200. doi: 10.1016/j.jagp.2014.12.003
    • (2014) Am. J. Geriatr. Psychiatry , vol.24 , pp. 192-200
    • Beristianos, M.H.1    Yaffe, K.2    Cohen, B.3    Byers, A.L.4
  • 3
    • 84947617144 scopus 로고    scopus 로고
    • Gene networks specific for innate immunity define post-traumatic stress disorder
    • Breen, M. S., Maihofer, A. X., Glatt, S. J., Tylee, D. S., Chandler, S. D., Tsuang, M. T., et al. (2015). Gene networks specific for innate immunity define post-traumatic stress disorder. Mol. Psychiatry 20, 1538-1545. doi: 10.1038/mp.2015.9
    • (2015) Mol. Psychiatry , vol.20 , pp. 1538-1545
    • Breen, M.S.1    Maihofer, A.X.2    Glatt, S.J.3    Tylee, D.S.4    Chandler, S.D.5    Tsuang, M.T.6
  • 4
    • 35148835708 scopus 로고    scopus 로고
    • Genetics of cardiovascular diseases: From single mutations to the whole genome
    • Cambien, F., and Tiret, L. (2007). Genetics of cardiovascular diseases: from single mutations to the whole genome. Circulation 116, 1714-1724. doi: 10.1161/circulationaha.106.661751
    • (2007) Circulation , vol.116 , pp. 1714-1724
    • Cambien, F.1    Tiret, L.2
  • 5
    • 0038217084 scopus 로고    scopus 로고
    • PKA and PKC enhance excitatory synaptic transmission in human dentate gyrus
    • Chen, H. X., and Roper, S. N. (2003). PKA and PKC enhance excitatory synaptic transmission in human dentate gyrus. J. Neurophysiol. 89, 2482-2488. doi: 10.1152/jn.01031.2002
    • (2003) J. Neurophysiol , vol.89 , pp. 2482-2488
    • Chen, H.X.1    Roper, S.N.2
  • 6
    • 2342522110 scopus 로고    scopus 로고
    • Shaping the nuclear action of NF-κB
    • Chen, L. F., and Greene, W. C. (2004). Shaping the nuclear action of NF-κB. Nat. Rev. Mol. Cell Biol. 5, 392-401. doi: 10.1038/nrm1368
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 392-401
    • Chen, L.F.1    Greene, W.C.2
  • 7
    • 84885418229 scopus 로고    scopus 로고
    • Crosstalk between dopamine D(2) receptors and cannabinoid CB(1) receptors regulates CNR1 promoter activity via ERK1/2 signaling
    • Chiang, Y. C., Lo, Y. N., and Chen, J. C. (2013). Crosstalk between dopamine D(2) receptors and cannabinoid CB(1) receptors regulates CNR1 promoter activity via ERK1/2 signaling. J. Neurochem. 127, 163-176. doi: 10.1111/jnc.12399
    • (2013) J. Neurochem , vol.127 , pp. 163-176
    • Chiang, Y.C.1    Lo, Y.N.2    Chen, J.C.3
  • 8
    • 84896842161 scopus 로고    scopus 로고
    • Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder
    • Cho, J. H., Lee, I., Hammamieh, R., Wang, K., Baxter, D., Scherler, K., et al. (2014). Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder. Proc. Natl. Acad. Sci. U.S.A. 111, 3188-3193. doi: 10.1073/pnas.1400113111
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 3188-3193
    • Cho, J.H.1    Lee, I.2    Hammamieh, R.3    Wang, K.4    Baxter, D.5    Scherler, K.6
  • 9
    • 0031446024 scopus 로고    scopus 로고
    • Two-year follow up study of stress-related disorders among immigrants to Israel from the Chernobyl area
    • Cwikel, J., Abdelgani, A., Goldsmith, J. R., Quastel, M., and Yevelson, I. I. (1997). Two-year follow up study of stress-related disorders among immigrants to Israel from the Chernobyl area. Environ. Health Perspect. 105(Suppl. 6), 1545-1550. doi: 10.2307/3433668
    • (1997) Environ. Health Perspect , vol.105 , pp. 1545-1550
    • Cwikel, J.1    Abdelgani, A.2    Goldsmith, J.R.3    Quastel, M.4    Yevelson, I.I.5
  • 10
    • 84923341407 scopus 로고    scopus 로고
    • A novel analytical brain block tool to enable functional annotation of discriminatory transcript biomarkers among discrete regions of the fronto-limbic circuit in primate brain
    • Dalgard, C. L., Jacobowitz, D. M., Singh, V. K., Saleem, K. S., Ursano, R. J., Starr, J. M., et al. (2015). A novel analytical brain block tool to enable functional annotation of discriminatory transcript biomarkers among discrete regions of the fronto-limbic circuit in primate brain. Brain Res. 1600, 42-58. doi: 10.1016/j.brainres.2014.12.031
    • (2015) Brain Res , vol.1600 , pp. 42-58
    • Dalgard, C.L.1    Jacobowitz, D.M.2    Singh, V.K.3    Saleem, K.S.4    Ursano, R.J.5    Starr, J.M.6
  • 11
    • 1542676772 scopus 로고    scopus 로고
    • A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells
    • Davis, M. I., Ronesi, J., and Lovinger, D. M. (2003). A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells. J. Biol. Chem. 278, 48973-48980. doi: 10.1074/jbc.M305697200
    • (2003) J. Biol. Chem , vol.278 , pp. 48973-48980
    • Davis, M.I.1    Ronesi, J.2    Lovinger, D.M.3
  • 12
    • 67651142330 scopus 로고    scopus 로고
    • The proinflammatory cytokines IL- 1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway
    • Gao, B., Calhoun, K., and Fang, D. (2006). The proinflammatory cytokines IL- 1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway. Arthritis Res. Ther. 8:R172. doi: 10.1186/ar2081
    • (2006) Arthritis Res. Ther , vol.8 , pp. R172
    • Gao, B.1    Calhoun, K.2    Fang, D.3
  • 13
    • 3042748507 scopus 로고    scopus 로고
    • Genetic markers: Progress and potential for cardiovascular disease
    • Gibbons, G. H., Liew, C. C., Goodarzi, M. O., Rotter, J. I., Hsueh, W. A., Siragy, H. M., et al. (2004). Genetic markers: progress and potential for cardiovascular disease. Circulation 109, Iv47-Iv58. doi: 10.1161/01.CIR.0000133440.86427.26
    • (2004) Circulation , vol.109 , pp. Iv47-Iv58
    • Gibbons, G.H.1    Liew, C.C.2    Goodarzi, M.O.3    Rotter, J.I.4    Hsueh, W.A.5    Siragy, H.M.6
  • 14
    • 70349539012 scopus 로고    scopus 로고
    • PTSD is associated with an excess of inflammatory immune activities
    • Gill, J. M., Saligan, L., Woods, S., and Page, G. (2009). PTSD is associated with an excess of inflammatory immune activities. Perspect. Psychiatr. Care 45, 262-277. doi: 10.1111/j.1744-6163.2009.00229.x
    • (2009) Perspect. Psychiatr. Care , vol.45 , pp. 262-277
    • Gill, J.M.1    Saligan, L.2    Woods, S.3    Page, G.4
  • 15
    • 84872914326 scopus 로고    scopus 로고
    • Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells
    • Gola, H., Engler, H., Sommershof, A., Adenauer, H., Kolassa, S., Schedlowski, M., et al. (2013). Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells. BMC Psychiatry 13:40. doi: 10.1186/1471-244X-13-40
    • (2013) BMC Psychiatry , vol.13 , pp. 40
    • Gola, H.1    Engler, H.2    Sommershof, A.3    Adenauer, H.4    Kolassa, S.5    Schedlowski, M.6
  • 16
    • 84947297455 scopus 로고    scopus 로고
    • PKCα-dependent augmentation of cAMP and CREB phosphorylation mediates the angiotensin II stimulation of renin in the collecting duct
    • Gonzalez, A. A., Liu, L., Lara, L. S., Bourgeois, C. R., Ibaceta-Gonzalez, C., Salinas-Parra, N., et al. (2015). PKCα-dependent augmentation of cAMP and CREB phosphorylation mediates the angiotensin II stimulation of renin in the collecting duct. Am. J. Physiol. Renal Physiol. 309, F880-F888. doi: 10.1152/ajprenal.00155.2015
    • (2015) Am. J. Physiol. Renal Physiol , vol.309 , pp. F880-F888
    • Gonzalez, A.A.1    Liu, L.2    Lara, L.S.3    Bourgeois, C.R.4    Ibaceta-Gonzalez, C.5    Salinas-Parra, N.6
  • 17
    • 0345826140 scopus 로고    scopus 로고
    • Cell type-specific expression of the IκB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-κB activation
    • Gustin, J. A., Ozes, O. N., Akca, H., Pincheira, R., Mayo, L. D., Li, Q., et al. (2004a). Cell type-specific expression of the IκB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-κB activation. J. Biol. Chem. 279, 1615-1620. doi: 10.1074/jbc.M306976200
    • (2004) J. Biol. Chem , vol.279 , pp. 1615-1620
    • Gustin, J.A.1    Ozes, O.N.2    Akca, H.3    Pincheira, R.4    Mayo, L.D.5    Li, Q.6
  • 18
    • 1442325382 scopus 로고    scopus 로고
    • Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells
    • Gustin, J. A., Pincheira, R., Mayo, L. D., Ozes, O. N., Kessler, K. M., Baerwald, M. R., et al. (2004b). Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells. Am. J. Physiol. Cell physiol. 286, C547-C555. doi: 10.1152/ajpcell.00332.2002
    • (2004) Am. J. Physiol. Cell Physiol , vol.286 , pp. C547-C555
    • Gustin, J.A.1    Pincheira, R.2    Mayo, L.D.3    Ozes, O.N.4    Kessler, K.M.5    Baerwald, M.R.6
  • 19
    • 33645796477 scopus 로고    scopus 로고
    • Cannabinoid receptor signaling
    • Howlett, A. C. (2005). Cannabinoid receptor signaling. Handb. Exp. Pharmacol. 168, 53-79. doi: 10.1007/3-540-26573-2_2
    • (2005) Handb. Exp. Pharmacol , vol.168 , pp. 53-79
    • Howlett, A.C.1
  • 20
    • 84898752877 scopus 로고    scopus 로고
    • The NIMH Research Domain Criteria (RDoC) Project: Precision medicine for psychiatry
    • Insel, T. R. (2014). The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry. Am J. Psychiatry 171, 395-397. doi: 10.1176/appi.ajp.2014.14020138
    • (2014) Am J. Psychiatry , vol.171 , pp. 395-397
    • Insel, T.R.1
  • 21
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • Joseph, S. B., Castrillo, A., Laffitte, B. A., Mangelsdorf, D. J., and Tontonoz, P. (2003). Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9, 213-219. doi: 10.1038/nm820
    • (2003) Nat. Med , vol.9 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Laffitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 22
    • 84871145783 scopus 로고    scopus 로고
    • An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: Evidence for candidate genes on human chromosome 2
    • Kim, J., Lee, T., Kim, T. H., Lee, K. T., and Kim, H. (2012). An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: evidence for candidate genes on human chromosome 2. BMC Genomics 13:711. doi: 10.1186/1471-2164-13-711
    • (2012) BMC Genomics , vol.13 , pp. 711
    • Kim, J.1    Lee, T.2    Kim, T.H.3    Lee, K.T.4    Kim, H.5
  • 23
    • 84875542865 scopus 로고    scopus 로고
    • Apolipoprotein E inhibits osteoclast differentiation via regulation of c-Fos, NFATc1 and NF-κB
    • Kim, W. S., Kim, H. J., Lee, Z. H., Lee, Y., and Kim, H. H. (2013). Apolipoprotein E inhibits osteoclast differentiation via regulation of c-Fos, NFATc1 and NF-κB. Exp. Cell Res. 319, 436-446. doi: 10.1016/j.yexcr.2012.12.004
    • (2013) Exp. Cell Res. , vol.319 , pp. 436-446
    • Kim, W.S.1    Kim, H.J.2    Lee, Z.H.3    Lee, Y.4    Kim, H.H.5
  • 24
    • 79955678047 scopus 로고    scopus 로고
    • The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1
    • King, C. C., Sastri, M., Chang, P., Pennypacker, J., and Taylor, S. S. (2011). The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1. PLoS ONE 6:e18713. doi: 10.1371/journal.pone.0018713
    • (2011) Plos ONE , vol.6 , pp. e18713
    • King, C.C.1    Sastri, M.2    Chang, P.3    Pennypacker, J.4    Taylor, S.S.5
  • 25
    • 84911895975 scopus 로고    scopus 로고
    • Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes
    • Kluth, O., Matzke, D., Schulze, G., Schwenk, R. W., Joost, H. G., and Schürmann, A. (2014). Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes. Diabetes 63, 4230-4238. doi: 10.2337/db14-0425
    • (2014) Diabetes , vol.63 , pp. 4230-4238
    • Kluth, O.1    Matzke, D.2    Schulze, G.3    Schwenk, R.W.4    Joost, H.G.5    Schürmann, A.6
  • 26
    • 84894571860 scopus 로고    scopus 로고
    • Causal analysis approaches in Ingenuity pathway analysis
    • Krämer, A., Green, J., Pollard, J. Jr., and Tugendreich, S. (2014). Causal analysis approaches in Ingenuity pathway analysis. Bioinformatics 30, 523-530. doi: 10.1093/bioinformatics/btt703
    • (2014) Bioinformatics , vol.30 , pp. 523-530
    • Krämer, A.1    Green, J.2    Pollard, J.3    Tugendreich, S.4
  • 27
    • 36148964068 scopus 로고    scopus 로고
    • Id-1 activation of PI3K/Akt/NFκB signaling pathway and its significance in promoting survival of esophageal cancer cells
    • Li, B., Cheung, P. Y., Wang, X., Tsao, S. W., Ling, M. T., Wong, Y. C., et al. (2007). Id-1 activation of PI3K/Akt/NFκB signaling pathway and its significance in promoting survival of esophageal cancer cells. Carcinogenesis 28, 2313-2320. doi: 10.1093/carcin/bgm152
    • (2007) Carcinogenesis , vol.28 , pp. 2313-2320
    • Li, B.1    Cheung, P.Y.2    Wang, X.3    Tsao, S.W.4    Ling, M.T.5    Wong, Y.C.6
  • 28
    • 84872790689 scopus 로고    scopus 로고
    • Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy
    • Liao, W., Lin, J. X., and Leonard, W. J. (2013). Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 38, 13-25. doi: 10.1016/j.immuni.2013.01.004
    • (2013) Immunity , vol.38 , pp. 13-25
    • Liao, W.1    Lin, J.X.2    Leonard, W.J.3
  • 29
    • 0025343895 scopus 로고
    • Activation of interleukin-6 gene expression through the NF-κB transcription factor
    • Libermann, T. A., and Baltimore, D. (1990). Activation of interleukin-6 gene expression through the NF-κB transcription factor. Mol. Cell. Biol. 10, 2327-2334. doi: 10.1128/mcb.10.5.2327
    • (1990) Mol. Cell. Biol , vol.10 , pp. 2327-2334
    • Libermann, T.A.1    Baltimore, D.2
  • 30
    • 84918836866 scopus 로고    scopus 로고
    • IL-1beta Upregulates IL-8 production in human muller cells through activation of the p38 MAPK and ERK1/2 signaling pathways
    • Liu, X., Ye, F., Xiong, H., Hu, D., Limb, G. A., Xie, T., et al. (2014). IL-1beta Upregulates IL-8 production in human muller cells through activation of the p38 MAPK and ERK1/2 signaling pathways. Inflammation 37, 1486-1495. doi: 10.1007/s10753-014-9874-5
    • (2014) Inflammation , vol.37 , pp. 1486-1495
    • Liu, X.1    Ye, F.2    Xiong, H.3    Hu, D.4    Limb, G.A.5    Xie, T.6
  • 31
    • 84881161107 scopus 로고    scopus 로고
    • A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus
    • Logue, M. W., Baldwin, C., Guffanti, G., Melista, E., Wolf, E. J., Reardon, A. F., et al. (2013). A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. Mol. Psychiatry 18, 937-942. doi: 10.1038/mp.2012.113
    • (2013) Mol. Psychiatry , vol.18 , pp. 937-942
    • Logue, M.W.1    Baldwin, C.2    Guffanti, G.3    Melista, E.4    Wolf, E.J.5    Reardon, A.F.6
  • 32
    • 0034747526 scopus 로고    scopus 로고
    • Interleukin-1β-induced promatrilysin expression is mediated by NFκB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP
    • Maliner-Stratton, M. S., Klein, R. D., Udayakumar, T. S., Nagle, R. B., and Bowden, G. T. (2001). Interleukin-1β-induced promatrilysin expression is mediated by NFκB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP. Neoplasia 3, 509-520. doi: 10.1038/sj/neo/7900178
    • (2001) Neoplasia , vol.3 , pp. 509-520
    • Maliner-Stratton, M.S.1    Klein, R.D.2    Udayakumar, T.S.3    Nagle, R.B.4    Bowden, G.T.5
  • 34
    • 84954271826 scopus 로고    scopus 로고
    • Network science and the human brain: Using graph theory to understand the brain and one of its hubs, the amygdala, in health and disease
    • Mears, D., and Pollard, H. B. (2016). Network science and the human brain: using graph theory to understand the brain and one of its hubs, the amygdala, in health and disease. J. Neurosci. Res. 94, 590-605. doi: 10.1002/jnr.23705
    • (2016) J. Neurosci. Res , vol.94 , pp. 590-605
    • Mears, D.1    Pollard, H.B.2
  • 35
    • 78649724603 scopus 로고    scopus 로고
    • Unifying candidate gene and GWAS Approaches in Asthma
    • Michel, S., Liang, L., Depner, M., Klopp, N., Ruether, A., Kumar, A., et al. (2010). Unifying candidate gene and GWAS Approaches in Asthma. PLoS ONE 5:e13894. doi: 10.1371/journal.pone.0013894
    • (2010) Plos ONE , vol.5 , pp. e13894
    • Michel, S.1    Liang, L.2    Depner, M.3    Klopp, N.4    Ruether, A.5    Kumar, A.6
  • 36
    • 0344875505 scopus 로고    scopus 로고
    • Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor
    • Nair, V. D., and Sealfon, S. C. (2003). Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. J. Biol. Chem. 278, 47053-47061. doi: 10.1074/jbc.M303364200
    • (2003) J. Biol. Chem , vol.278 , pp. 47053-47061
    • Nair, V.D.1    Sealfon, S.C.2
  • 37
    • 0041932370 scopus 로고    scopus 로고
    • Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity
    • Patel, S., Rademacher, D. J., and Hillard, C. J. (2003). Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. J. Pharmacol. Exp. Ther. 306, 880-888. doi: 10.1124/jpet.103.054270
    • (2003) J. Pharmacol. Exp. Ther , vol.306 , pp. 880-888
    • Patel, S.1    Rademacher, D.J.2    Hillard, C.J.3
  • 38
    • 84874019208 scopus 로고    scopus 로고
    • The impact of posttraumatic stress disorder on blood pressure and heart rate in a veteran population
    • Paulus, E. J., Argo, T. R., and Egge, J. A. (2013). The impact of posttraumatic stress disorder on blood pressure and heart rate in a veteran population. J. Trauma. Stress 26, 169-172. doi: 10.1002/jts.21785
    • (2013) J. Trauma. Stress , vol.26 , pp. 169-172
    • Paulus, E.J.1    Argo, T.R.2    Egge, J.A.3
  • 39
    • 84880959704 scopus 로고    scopus 로고
    • CIAP-2 protects cardiac fibroblasts from oxidative damage: An obligate regulatory role for ERK1/2 MAPK and NF-κB
    • Philip, L., and Shivakumar, K. (2013). cIAP-2 protects cardiac fibroblasts from oxidative damage: an obligate regulatory role for ERK1/2 MAPK and NF-κB. J. Mol. Cell. Cardiol. 62, 217-226. doi: 10.1016/j.yjmcc.2013.06.009
    • (2013) J. Mol. Cell. Cardiol , vol.62 , pp. 217-226
    • Philip, L.1    Shivakumar, K.2
  • 40
    • 84924388081 scopus 로고    scopus 로고
    • Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors?
    • Rankinen, T., Sarzynski, M. A., Ghosh, S., and Bouchard, C. (2015). Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors? Circ. Res. 116, 909-922. doi: 10.1161/CIRCRESAHA.116.302888
    • (2015) Circ. Res , vol.116 , pp. 909-922
    • Rankinen, T.1    Sarzynski, M.A.2    Ghosh, S.3    Bouchard, C.4
  • 41
    • 84924705842 scopus 로고    scopus 로고
    • Posttraumatic stress disorder and incident heart failure among a community-based sample of US Veterans
    • Roy, S. S., Foraker, R. E., Girton, R. A., and Mansfield, A. J. (2015). Posttraumatic stress disorder and incident heart failure among a community-based sample of US Veterans. Am. J. Public Health 105, 757-763. doi: 10.2105/AJPH.2014.302342
    • (2015) Am. J. Public Health , vol.105 , pp. 757-763
    • Roy, S.S.1    Foraker, R.E.2    Girton, R.A.3    Mansfield, A.J.4
  • 42
    • 17144470224 scopus 로고    scopus 로고
    • Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction
    • Sánchez, M. G., Ruiz-Llorente, L., Sánchez, A. M., and Díaz-Laviada, I. (2003). Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction. Cell. Signal. 15, 851-859. doi: 10.1016/S0898-6568(03)00036-6
    • (2003) Cell. Signal , vol.15 , pp. 851-859
    • Sánchez, M.G.1    Ruiz-Llorente, L.2    Sánchez, A.M.3    Díaz-Laviada, I.4
  • 43
    • 66749117828 scopus 로고    scopus 로고
    • IL-1β augments TNF-α-mediated inflammatory responses from lung epithelial cells
    • Saperstein, S., Chen, L., Oakes, D., Pryhuber, G., and Finkelstein, J. (2009). IL-1β augments TNF-α-mediated inflammatory responses from lung epithelial cells. J. interferon Cytokine Res. 29, 273-284. doi: 10.1089/jir.2008.0076
    • (2009) J. Interferon Cytokine Res. , vol.29 , pp. 273-284
    • Saperstein, S.1    Chen, L.2    Oakes, D.3    Pryhuber, G.4    Finkelstein, J.5
  • 44
    • 0034669171 scopus 로고    scopus 로고
    • Role of LXRs in control of lipogenesis
    • Schultz, J. R., Tu, H., Luk, A., Repa, J. J., Medina, J. C., Li, L., et al. (2000). Role of LXRs in control of lipogenesis. Genes Dev. 14, 2831-2838. doi: 10.1101/gad.850400
    • (2000) Genes Dev , vol.14 , pp. 2831-2838
    • Schultz, J.R.1    Tu, H.2    Luk, A.3    Repa, J.J.4    Medina, J.C.5    Li, L.6
  • 45
    • 0024564514 scopus 로고
    • Interleukin 1 and cyclic AMP induce κ immunoglobulin light-chain expression via activation of an NF-κB-like DNA-binding protein
    • Shirakawa, F., Chedid, M., Suttles, J., Pollok, B. A., and Mizel, S. B. (1989). Interleukin 1 and cyclic AMP induce κ immunoglobulin light-chain expression via activation of an NF-κB-like DNA-binding protein. Mol. Cell. Biol. 9, 959-964. doi: 10.1128/MCB.9.3.959
    • (1989) Mol. Cell. Biol , vol.9 , pp. 959-964
    • Shirakawa, F.1    Chedid, M.2    Suttles, J.3    Pollok, B.A.4    Mizel, S.B.5
  • 46
    • 0024355977 scopus 로고
    • In vitro activation and nuclear translocation of NF-κB catalyzed by cyclic AMP-dependent protein kinase and protein kinase C
    • Shirakawa, F., and Mizel, S. B. (1989). In vitro activation and nuclear translocation of NF-κB catalyzed by cyclic AMP-dependent protein kinase and protein kinase C. Mol. Cell. Biol. 9, 2424-2430.
    • (1989) Mol. Cell. Biol , vol.9 , pp. 2424-2430
    • Shirakawa, F.1    Mizel, S.B.2
  • 47
    • 84883476475 scopus 로고    scopus 로고
    • Post-traumatic stress disorder and coronary heart disease
    • Sidney, S. (2013). Post-traumatic stress disorder and coronary heart disease. J. Am. Coll. Cardiol. 62, 979-980. doi: 10.1016/j.jacc.2013.06.005
    • (2013) J. Am. Coll. Cardiol , vol.62 , pp. 979-980
    • Sidney, S.1
  • 48
    • 84964687940 scopus 로고    scopus 로고
    • Integrative multi-omic analysis of human platelet eQTLs reveals alternative start site in Mitofusin 2
    • Simon, L. M., Chen, E. S., Edelstein, L. C., Kong, X., Bhatlekar, S., Rigoutsos, I., et al. (2016). Integrative multi-omic analysis of human platelet eQTLs reveals alternative start site in Mitofusin 2. Am. J. Hum. Genet. 98, 883-897. doi: 10.1016/j.ajhg.2016.03.007
    • (2016) Am. J. Hum. Genet , vol.98 , pp. 883-897
    • Simon, L.M.1    Chen, E.S.2    Edelstein, L.C.3    Kong, X.4    Bhatlekar, S.5    Rigoutsos, I.6
  • 49
    • 84978159607 scopus 로고    scopus 로고
    • Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers
    • Stein, M. B., Chen, C. Y., Ursano, R. J., Cai, T., Gelernter, J., Heeringa, S. G., et al. (2016). Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers. JAMA Psychiatry. 73, 695-704. doi: 10.1001/jamapsychiatry.2016.0350
    • (2016) JAMA Psychiatry , vol.73 , pp. 695-704
    • Stein, M.B.1    Chen, C.Y.2    Ursano, R.J.3    Cai, T.4    Gelernter, J.5    Heeringa, S.G.6
  • 50
    • 0036255811 scopus 로고    scopus 로고
    • Candidate-gene approaches for studying complex genetic traits: Practical considerations
    • Tabor, H. K., Risch, N. J., and Myers, R. M. (2002). Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat. Rev. Genet. 3, 391-397. doi: 10.1038/nrg796
    • (2002) Nat. Rev. Genet , vol.3 , pp. 391-397
    • Tabor, H.K.1    Risch, N.J.2    Myers, R.M.3
  • 51
    • 0346102602 scopus 로고    scopus 로고
    • Different effects of five dopamine receptor subtypes on nuclear factor-κB activity in NG108-15 cells and mouse brain
    • Takeuchi, Y., and Fukunaga, K. (2004). Different effects of five dopamine receptor subtypes on nuclear factor-κB activity in NG108-15 cells and mouse brain. J. Neurochem. 88, 41-50. doi: 10.1046/j.1471-4159.2003.02129.x
    • (2004) J. Neurochem , vol.88 , pp. 41-50
    • Takeuchi, Y.1    Fukunaga, K.2
  • 52
    • 84887241085 scopus 로고    scopus 로고
    • Objective evidence of myocardial ischemia in patients with posttraumatic stress disorder
    • Turner, J. H., Neylan, T. C., Schiller, N. B., Li, Y., and Cohen, B. E. (2013). Objective evidence of myocardial ischemia in patients with posttraumatic stress disorder. Biol. Psychiatry 74, 861-866. doi: 10.1016/j.biopsych.2013.07.012
    • (2013) Biol. Psychiatry , vol.74 , pp. 861-866
    • Turner, J.H.1    Neylan, T.C.2    Schiller, N.B.3    Li, Y.4    Cohen, B.E.5
  • 53
    • 84903783002 scopus 로고    scopus 로고
    • Posttraumatic stress disorder and incidence of type-2 diabetes: A prospective twin study
    • Vaccarino, V., Goldberg, J., Magruder, K. M., Forsberg, C. W., Friedman, M. J., Litz, B. T., et al. (2014). Posttraumatic stress disorder and incidence of type-2 diabetes: a prospective twin study. J. Psychiatr. Res. 56, 158-164. doi: 10.1016/j.jpsychires.2014.05.019
    • (2014) J. Psychiatr. Res , vol.56 , pp. 158-164
    • Vaccarino, V.1    Goldberg, J.2    Magruder, K.M.3    Forsberg, C.W.4    Friedman, M.J.5    Litz, B.T.6
  • 54
    • 84883482591 scopus 로고    scopus 로고
    • Post-traumatic stress disorder and incidence of coronary heart disease: A twin study
    • Vaccarino, V., Goldberg, J., Rooks, C., Shah, A. J., Veledar, E., Faber, T. L., et al. (2013). Post-traumatic stress disorder and incidence of coronary heart disease: a twin study. J. Am. Coll. Cardiol. 62, 970-978. doi: 10.1016/j.jacc.2013.04.085
    • (2013) J. Am. Coll. Cardiol , vol.62 , pp. 970-978
    • Vaccarino, V.1    Goldberg, J.2    Rooks, C.3    Shah, A.J.4    Veledar, E.5    Faber, T.L.6
  • 55
    • 66949165544 scopus 로고    scopus 로고
    • NF-κ Bp50 regulates C/EBPα expression and inflammatory cytokine-induced neutrophil production
    • Wang, D., Paz-Priel, I., and Friedman, A. D. (2009). NF-κ Bp50 regulates C/EBPα expression and inflammatory cytokine-induced neutrophil production. J. Immunol. 182, 5757-5762. doi: 10.4049/jimmunol.0803861
    • (2009) J. Immunol , vol.182 , pp. 5757-5762
    • Wang, D.1    Paz-Priel, I.2    Friedman, A.D.3
  • 56
    • 84868093966 scopus 로고    scopus 로고
    • The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements
    • Wang, V. Y., Huang, W., Asagiri, M., Spann, N., Hoffmann, A., Glass, C., et al. (2012). The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements. Cell Rep. 2, 824-839. doi: 10.1016/j.celrep.2012.08.042
    • (2012) Cell Rep , vol.2 , pp. 824-839
    • Wang, V.Y.1    Huang, W.2    Asagiri, M.3    Spann, N.4    Hoffmann, A.5    Glass, C.6
  • 57
    • 84867525729 scopus 로고    scopus 로고
    • Focal adhesion kinase activates NF-κB via the ERK1/2 and p38MAPK Pathways in amyloid-beta25-35-induced apoptosis in PC12 cells
    • Wang, X., Chen, Q., and Xing, D. (2012). Focal adhesion kinase activates NF-κB via the ERK1/2 and p38MAPK Pathways in amyloid-beta25-35-induced apoptosis in PC12 cells. J. Alzheimers Dis. 32, 77-94. doi: 10.3233/JAD-2012-120526
    • (2012) J. Alzheimers Dis , vol.32 , pp. 77-94
    • Wang, X.1    Chen, Q.2    Xing, D.3
  • 58
    • 78650666211 scopus 로고    scopus 로고
    • The role of the transcription factor CREB in immune function
    • Wen, A. Y., Sakamoto, K. M., and Miller, L. S. (2010). The role of the transcription factor CREB in immune function. J. Immunol. 185, 6413-6419. doi: 10.4049/jimmunol.1001829
    • (2010) J. Immunol , vol.185 , pp. 6413-6419
    • Wen, A.Y.1    Sakamoto, K.M.2    Miller, L.S.3
  • 59
    • 84871748027 scopus 로고    scopus 로고
    • Post-traumatic stress disorder: A fast track to premature cardiovascular disease?
    • Wentworth, B. A., Stein, M. B., Redwine, L. S., Xue, Y., Taub, P. R., Clopton, P., et al. (2013). Post-traumatic stress disorder: a fast track to premature cardiovascular disease? Cardiol. Rev. 21, 16-22. doi: 10.1097/crd.0b013e318265343b
    • (2013) Cardiol. Rev , vol.21 , pp. 16-22
    • Wentworth, B.A.1    Stein, M.B.2    Redwine, L.S.3    Xue, Y.4    Taub, P.R.5    Clopton, P.6
  • 60
    • 0031423761 scopus 로고    scopus 로고
    • Pillars article: MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
    • Wesche, H., Henzel, W. J., Shillinglaw, W., Li, S., and Cao, Z. (2013). Pillars article: MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 1997. 7: 837-847.
    • (2013) Immunity , vol.7 , pp. 837-847
    • Wesche, H.1    Henzel, W.J.2    Shillinglaw, W.3    Li, S.4    Cao, Z.5
  • 61
    • 84901987345 scopus 로고    scopus 로고
    • Genetic insights into cardiometabolic risk factors
    • Whitfield, J. B. (2014). Genetic insights into cardiometabolic risk factors. Clin. Biochem. Rev. 35, 15-36.
    • (2014) Clin. Biochem. Rev , vol.35 , pp. 15-36
    • Whitfield, J.B.1
  • 62
    • 84924430270 scopus 로고    scopus 로고
    • Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes
    • Wood, A. R., Tuke, M. A., Nalls, M., Hernandez, D., Gibbs, J. R., Lin, H., et al. (2015). Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes. Hum. Mol. Genet. 24, 1504-1512. doi: 10.1093/hmg/ddu560
    • (2015) Hum. Mol. Genet , vol.24 , pp. 1504-1512
    • Wood, A.R.1    Tuke, M.A.2    Nalls, M.3    Hernandez, D.4    Gibbs, J.R.5    Lin, H.6
  • 63
    • 0020214219 scopus 로고
    • Jacob Mendez DaCosta: Medical teacher, clinician, and clinical investigator
    • Wooley, C. F. (1982). Jacob Mendez DaCosta: medical teacher, clinician, and clinical investigator. Am. J. Cardiol. 50, 1145-1148. doi: 10.1016/0002-9149(82)90434-9
    • (1982) Am. J. Cardiol , vol.50 , pp. 1145-1148
    • Wooley, C.F.1
  • 64
    • 84885424758 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder
    • Xie, P., Kranzler, H. R., Yang, C., Zhao, H., Farrer, L. A., and Gelernter, J. (2013). Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol. Psychiatry 74, 656-663. doi: 10.1016/j.biopsych.2013.04.013
    • (2013) Biol. Psychiatry , vol.74 , pp. 656-663
    • Xie, P.1    Kranzler, H.R.2    Yang, C.3    Zhao, H.4    Farrer, L.A.5    Gelernter, J.6
  • 65
    • 0037417136 scopus 로고    scopus 로고
    • Identification of NF-κB-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference
    • Zhou, A., Scoggin, S., Gaynor, R. B., and Williams, N. S. (2003). Identification of NF-κB-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference. Oncogene 22, 2054-2064. doi: 10.1038/sj.onc.1206262
    • (2003) Oncogene , vol.22 , pp. 2054-2064
    • Zhou, A.1    Scoggin, S.2    Gaynor, R.B.3    Williams, N.S.4
  • 66
    • 84899724278 scopus 로고    scopus 로고
    • Dysregulation in microRNA expression is associated with alterations in immune functions in combat veterans with post-traumatic stress disorder
    • Zhou, J., Nagarkatti, P., Zhong, Y., Ginsberg, J. P., Singh, N. P., Zhang, J., et al. (2014). Dysregulation in microRNA expression is associated with alterations in immune functions in combat veterans with post-traumatic stress disorder. PLoS ONE 9:e94075. doi: 10.1371/journal.pone.0094075
    • (2014) Plos ONE , vol.9 , pp. e94075
    • Zhou, J.1    Nagarkatti, P.2    Zhong, Y.3    Ginsberg, J.P.4    Singh, N.P.5    Zhang, J.6


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