메뉴 건너뛰기




Volumn 13, Issue , 2013, Pages

Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells

Author keywords

Cytokines; Immune system; Inflammation; Posttraumatic stress disorder; Pro inflammatory cytokines; Traumatic stress

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84872914326     PISSN: None     EISSN: 1471244X     Source Type: Journal    
DOI: 10.1186/1471-244X-13-40     Document Type: Article
Times cited : (174)

References (39)
  • 2
    • 12944331139 scopus 로고    scopus 로고
    • Psychological trauma and evidence for enhanced vulnerability for posttraumatic stress disorder through previous trauma among West Nile refugees
    • 10.1186/1471-244X-4-34, 529265, 15504233
    • Neuner F, Schauer M, Karunakara U, Klaschik C, Robert C, Elbert T. Psychological trauma and evidence for enhanced vulnerability for posttraumatic stress disorder through previous trauma among West Nile refugees. BMC Psychiatry 2004, 4:34. 10.1186/1471-244X-4-34, 529265, 15504233.
    • (2004) BMC Psychiatry , vol.4 , pp. 34
    • Neuner, F.1    Schauer, M.2    Karunakara, U.3    Klaschik, C.4    Robert, C.5    Elbert, T.6
  • 3
    • 74749101062 scopus 로고    scopus 로고
    • The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism
    • 10.1016/j.biopsych.2009.10.009, 19944409
    • Kolassa IT, Kolassa S, Ertl V, Papassotiropoulos A, De Quervain DJ. The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism. Biol Psychiatry 2010, 67:304-308. 10.1016/j.biopsych.2009.10.009, 19944409.
    • (2010) Biol Psychiatry , vol.67 , pp. 304-308
    • Kolassa, I.T.1    Kolassa, S.2    Ertl, V.3    Papassotiropoulos, A.4    De Quervain, D.J.5
  • 4
    • 84870465485 scopus 로고
    • Washington DC: American Psychiatric Association, American Psychiatric Association
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) 1994, Washington DC: American Psychiatric Association, American Psychiatric Association.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
  • 5
    • 0033211359 scopus 로고    scopus 로고
    • Physical health and post-traumatic stress disorder: review and synthesis
    • Schnurr PP, Jankowski MK. Physical health and post-traumatic stress disorder: review and synthesis. Semin Clin Neuropsychiatry 1999, 4:295-304.
    • (1999) Semin Clin Neuropsychiatry , vol.4 , pp. 295-304
    • Schnurr, P.P.1    Jankowski, M.K.2
  • 6
    • 4143059341 scopus 로고    scopus 로고
    • Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies
    • 10.1196/annals.1314.011, 15677401
    • Boscarino JA. Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies. Ann N Y Acad Sci 2004, 1032:141-153. 10.1196/annals.1314.011, 15677401.
    • (2004) Ann N Y Acad Sci , vol.1032 , pp. 141-153
    • Boscarino, J.A.1
  • 7
    • 0037383601 scopus 로고    scopus 로고
    • Health care costs associated with posttraumatic stress disorder symptoms in women
    • 10.1001/archpsyc.60.4.369, 12695314
    • Walker EA, Katon W, Russo J, Ciechanowski P, Newman E, Wagner AW. Health care costs associated with posttraumatic stress disorder symptoms in women. Arch Gen Psychiatry 2003, 60:369-374. 10.1001/archpsyc.60.4.369, 12695314.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 369-374
    • Walker, E.A.1    Katon, W.2    Russo, J.3    Ciechanowski, P.4    Newman, E.5    Wagner, A.W.6
  • 8
    • 33947647297 scopus 로고    scopus 로고
    • Is post-traumatic stress disorder related to development of heart disease?
    • 10.2217/14796678.3.2.153, 19804243
    • Kubzansky LD, Koenen KC. Is post-traumatic stress disorder related to development of heart disease?. Future Cardiol 2007, 3:153-156. 10.2217/14796678.3.2.153, 19804243.
    • (2007) Future Cardiol , vol.3 , pp. 153-156
    • Kubzansky, L.D.1    Koenen, K.C.2
  • 9
    • 33846031991 scopus 로고    scopus 로고
    • Prospective study of posttraumatic stress disorder symptoms and coronary heart disease in the normative aging study
    • 10.1001/archpsyc.64.1.109, 17199060
    • Kubzansky LD, Koenen KC, Spiro A, Vokonas PS, Sparrow D. Prospective study of posttraumatic stress disorder symptoms and coronary heart disease in the normative aging study. Arch Gen Psychiatry 2007, 64:109-116. 10.1001/archpsyc.64.1.109, 17199060.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 109-116
    • Kubzansky, L.D.1    Koenen, K.C.2    Spiro, A.3    Vokonas, P.S.4    Sparrow, D.5
  • 10
    • 52049116513 scopus 로고    scopus 로고
    • A prospective study of PTSD and early-age heart disease mortality among Vietnam veterans: implications for surveillance and prevention
    • 10.1097/PSY.0b013e31817bccaf, 3552245, 18596248
    • Boscarino JA. A prospective study of PTSD and early-age heart disease mortality among Vietnam veterans: implications for surveillance and prevention. Psychosom Med 2008, 70:668-676. 10.1097/PSY.0b013e31817bccaf, 3552245, 18596248.
    • (2008) Psychosom Med , vol.70 , pp. 668-676
    • Boscarino, J.A.1
  • 12
    • 34247547482 scopus 로고    scopus 로고
    • Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder
    • 10.1016/j.jpsychires.2006.06.009, 16901505
    • von Kanel R, Hepp U, Kraemer B, Traber R, Keel M, Mica L, Schnyder U. Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. J Psychiatr Res 2007, 41:744-752. 10.1016/j.jpsychires.2006.06.009, 16901505.
    • (2007) J Psychiatr Res , vol.41 , pp. 744-752
    • von Kanel, R.1    Hepp, U.2    Kraemer, B.3    Traber, R.4    Keel, M.5    Mica, L.6    Schnyder, U.7
  • 13
    • 2642535951 scopus 로고    scopus 로고
    • Inflammation as a cardiovascular risk factor
    • Willerson JT, Ridker PM. Inflammation as a cardiovascular risk factor. Circulation 2004, 109:II2-10.
    • (2004) Circulation , vol.109
    • Willerson, J.T.1    Ridker, P.M.2
  • 14
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • 10.1038/nature01323, 12490960
    • Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874. 10.1038/nature01323, 12490960.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 15
    • 3042520734 scopus 로고    scopus 로고
    • Neuroimmune and cortisol changes in selective serotonin reuptake inhibitor and placebo treatment of chronic posttraumatic stress disorder
    • 10.1016/j.biopsych.2004.03.009, 15231444
    • Tucker P, Ruwe WD, Masters B, Parker DE, Hossain A, Trautman RP, Wyatt DB. Neuroimmune and cortisol changes in selective serotonin reuptake inhibitor and placebo treatment of chronic posttraumatic stress disorder. Biol Psychiatry 2004, 56:121-128. 10.1016/j.biopsych.2004.03.009, 15231444.
    • (2004) Biol Psychiatry , vol.56 , pp. 121-128
    • Tucker, P.1    Ruwe, W.D.2    Masters, B.3    Parker, D.E.4    Hossain, A.5    Trautman, R.P.6    Wyatt, D.B.7
  • 16
    • 0030846197 scopus 로고    scopus 로고
    • Elevated levels of serum interleukin-1 beta in combat-related posttraumatic stress disorder
    • 10.1016/S0006-3223(96)00375-7, 9276074
    • Spivak B, Shohat B, Mester R, Avraham S, Gil-Ad I, Bleich A, Valevski A, Weizman A. Elevated levels of serum interleukin-1 beta in combat-related posttraumatic stress disorder. Biol Psychiatry 1997, 42:345-348. 10.1016/S0006-3223(96)00375-7, 9276074.
    • (1997) Biol Psychiatry , vol.42 , pp. 345-348
    • Spivak, B.1    Shohat, B.2    Mester, R.3    Avraham, S.4    Gil-Ad, I.5    Bleich, A.6    Valevski, A.7    Weizman, A.8
  • 17
    • 0033120020 scopus 로고    scopus 로고
    • Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events
    • 10.1016/S0006-3223(98)00131-0, 10202570
    • Maes M, Lin AH, Delmeire L, Van Gastel A, Kenis G, De Jongh R, Bosmans E. Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events. Biol Psychiatry 1999, 45:833-839. 10.1016/S0006-3223(98)00131-0, 10202570.
    • (1999) Biol Psychiatry , vol.45 , pp. 833-839
    • Maes, M.1    Lin, A.H.2    Delmeire, L.3    Van Gastel, A.4    Kenis, G.5    De Jongh, R.6    Bosmans, E.7
  • 19
    • 72149124501 scopus 로고    scopus 로고
    • Association of posttraumatic stress disorder with low-grade elevation of C-reactive protein: evidence from the general population
    • 10.1016/j.jpsychires.2009.06.002, 19628221
    • Spitzer C, Barnow S, Volzke H, Wallaschofski H, John U, Freyberger HJ, Lowe B, Grabe HJ. Association of posttraumatic stress disorder with low-grade elevation of C-reactive protein: evidence from the general population. J Psychiatr Res 2010, 44:15-21. 10.1016/j.jpsychires.2009.06.002, 19628221.
    • (2010) J Psychiatr Res , vol.44 , pp. 15-21
    • Spitzer, C.1    Barnow, S.2    Volzke, H.3    Wallaschofski, H.4    John, U.5    Freyberger, H.J.6    Lowe, B.7    Grabe, H.J.8
  • 20
    • 40349093516 scopus 로고    scopus 로고
    • Disturbance of serum interleukin-2 and interleukin-8 levels in posttraumatic and non-posttraumatic stress disorder earthquake survivors in northern China
    • 10.1159/000112050, 18073500
    • Song Y, Zhou D, Guan Z, Wang X. Disturbance of serum interleukin-2 and interleukin-8 levels in posttraumatic and non-posttraumatic stress disorder earthquake survivors in northern China. Neuroimmunomodulation 2007, 14:248-254. 10.1159/000112050, 18073500.
    • (2007) Neuroimmunomodulation , vol.14 , pp. 248-254
    • Song, Y.1    Zhou, D.2    Guan, Z.3    Wang, X.4
  • 21
    • 1542604598 scopus 로고    scopus 로고
    • The inflammatory markers C-reactive protein and serum amyloid A in refugees with and without posttraumatic stress disorder
    • 10.1016/j.cccn.2003.12.019, 15026269
    • Sondergaard HP, Hansson LO, Theorell T. The inflammatory markers C-reactive protein and serum amyloid A in refugees with and without posttraumatic stress disorder. Clin Chim Acta 2004, 342:93-98. 10.1016/j.cccn.2003.12.019, 15026269.
    • (2004) Clin Chim Acta , vol.342 , pp. 93-98
    • Sondergaard, H.P.1    Hansson, L.O.2    Theorell, T.3
  • 22
    • 1642320206 scopus 로고    scopus 로고
    • Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder
    • 10.1016/j.biopsych.2003.11.018, 15039004
    • Rohleder N, Joksimovic L, Wolf JM, Kirschbaum C. Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder. Biol Psychiatry 2004, 55:745-751. 10.1016/j.biopsych.2003.11.018, 15039004.
    • (2004) Biol Psychiatry , vol.55 , pp. 745-751
    • Rohleder, N.1    Joksimovic, L.2    Wolf, J.M.3    Kirschbaum, C.4
  • 23
    • 61849166110 scopus 로고    scopus 로고
    • Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD
    • 10.1002/jts.20372, 2829297, 19107725
    • Gill J, Vythilingam M, Page GG. Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD. J Trauma Stress 2008, 21:530-539. 10.1002/jts.20372, 2829297, 19107725.
    • (2008) J Trauma Stress , vol.21 , pp. 530-539
    • Gill, J.1    Vythilingam, M.2    Page, G.G.3
  • 26
    • 0141993086 scopus 로고    scopus 로고
    • A new approach to the assessment of the treatment effects of somatoform disorders
    • 10.1176/appi.psy.44.6.492, 14597684
    • Rief W, Hiller W. A new approach to the assessment of the treatment effects of somatoform disorders. Psychosomatics 2003, 44:492-498. 10.1176/appi.psy.44.6.492, 14597684.
    • (2003) Psychosomatics , vol.44 , pp. 492-498
    • Rief, W.1    Hiller, W.2
  • 28
    • 0032421570 scopus 로고    scopus 로고
    • The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • quiz 34-57
    • Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC. The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998, 59(Suppl 20):22-33. quiz 34-57.
    • (1998) J Clin Psychiatry , vol.59 , Issue.SUPPL. 20 , pp. 22-33
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavs, J.5    Weiller, E.6    Hergueta, T.7    Baker, R.8    Dunbar, G.C.9
  • 29
    • 72949151592 scopus 로고
    • A rating scale for depression
    • 10.1136/jnnp.23.1.56, 495331, 14399272
    • Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960, 23:56-62. 10.1136/jnnp.23.1.56, 495331, 14399272.
    • (1960) J Neurol Neurosurg Psychiatry , vol.23 , pp. 56-62
    • Hamilton, M.1
  • 30
    • 2642574503 scopus 로고    scopus 로고
    • Vienna, Austria: R Foundation for Statistical Computing, R Development Core Team: R
    • R Development Core Team: R A language and environment for statistical computing 2010, Vienna, Austria: R Foundation for Statistical Computing, R Development Core Team: R.
    • (2010) A language and environment for statistical computing
  • 32
    • 0033241810 scopus 로고    scopus 로고
    • An empirical comparison of permutation methods for tests of partial regression coefficients in a linear model
    • Anderson MJ, Legendre P. An empirical comparison of permutation methods for tests of partial regression coefficients in a linear model. J Stat Comput Simul 1999, 62:271-303.
    • (1999) J Stat Comput Simul , vol.62 , pp. 271-303
    • Anderson, M.J.1    Legendre, P.2
  • 33
    • 0035095424 scopus 로고    scopus 로고
    • Misunderstanding analysis of covariance
    • Miller GA, Chapman JP. Misunderstanding analysis of covariance. J Abnorm Psychol 2001, 110:40-48.
    • (2001) J Abnorm Psychol , vol.110 , pp. 40-48
    • Miller, G.A.1    Chapman, J.P.2
  • 34
    • 0014149425 scopus 로고
    • A paradox in the interpretation of group comparisons
    • Lord FM. A paradox in the interpretation of group comparisons. Psychol Bull 1967, 68:304-305.
    • (1967) Psychol Bull , vol.68 , pp. 304-305
    • Lord, F.M.1
  • 35
    • 0002294347 scopus 로고
    • A simple sequentially rejective multiple test procedur
    • Holm S. A simple sequentially rejective multiple test procedur. Scand J Stat 1979, 6:65-70.
    • (1979) Scand J Stat , vol.6 , pp. 65-70
    • Holm, S.1
  • 36
    • 0034904564 scopus 로고    scopus 로고
    • Biology of posttraumatic stress disorder
    • Yehuda R. Biology of posttraumatic stress disorder. J Clin Psychiatry 2001, 62(Suppl 17):41-46.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 17 , pp. 41-46
    • Yehuda, R.1
  • 38
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: friend or foe in immunity to infection?
    • 10.1038/nri1485, 15516964
    • Mills KH. Regulatory T cells: friend or foe in immunity to infection?. Nat Rev Immunol 2004, 4:841-855. 10.1038/nri1485, 15516964.
    • (2004) Nat Rev Immunol , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 39
    • 33744475829 scopus 로고    scopus 로고
    • Regulating inflammation by glucocorticoids
    • Besedovsky HO, del Rey A. Regulating inflammation by glucocorticoids. Nat Immunol 2006, 7:537.
    • (2006) Nat Immunol , vol.7 , pp. 537
    • Besedovsky, H.O.1    del Rey, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.