-
1
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
J. S. de Bono, C. J. Logothetis, A. Molina, K. Fizazi, S. North, L. Chu, K. N. Chi, R. J. Jones, O. B. Goodman Jr., F. Saad, J. N. Staffurth, P. Mainwaring, S. Harland, T. W. Flaig, T. E. Hutson, T. Cheng, H. Patterson, J. D. Hainsworth, C. J. Ryan, C. N. Sternberg, S. L. Ellard, A. Fléchon, M. Saleh, M. Scholz, E. Efstathiou, A. Zivi, D. Bianchini, Y. Loriot, N. Chieffo, T. Kheoh, C. M. Haqq, H. I. Scher; COU-AA-301 Investigators, Abiraterone and increased survival in metastatic prostate cancer. N. Engl. J. Med. 364, 1995-2005 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
Chu, L.6
Chi, K.N.7
Jones, R.J.8
Goodman, O.B.9
Saad, F.10
Staffurth, J.N.11
Mainwaring, P.12
Harland, S.13
Flaig, T.W.14
Hutson, T.E.15
Cheng, T.16
Patterson, H.17
Hainsworth, J.D.18
Ryan, C.J.19
Sternberg, C.N.20
Ellard, S.L.21
Fléchon, A.22
Saleh, M.23
Scholz, M.24
Efstathiou, E.25
Zivi, A.26
Bianchini, D.27
Loriot, Y.28
Chieffo, N.29
Kheoh, T.30
Haqq, C.M.31
Scher, H.I.32
more..
-
2
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
H. I. Scher, K. Fizazi, F. Saad, M.-E. Taplin, C. N. Sternberg, K. Miller, R. de Wit, P. Mulders, K. N. Chi, N. D. Shore, A. J. Armstrong, T. W. Flaig, A. Fléchon, P. Mainwaring, M. Fleming, J. D. Hainsworth, M. Hirmand, B. Selby, L. Seely, J. S. de Bono; AFFIRM Investigators, Increased survival with enzalutamide in prostate cancer after chemotherapy. N. Engl. J. Med. 367, 1187-1197 (2012).
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
Taplin, M.-E.4
Sternberg, C.N.5
Miller, K.6
De Wit, R.7
Mulders, P.8
Chi, K.N.9
Shore, N.D.10
Armstrong, A.J.11
Flaig, T.W.12
Fléchon, A.13
Mainwaring, P.14
Fleming, M.15
Hainsworth, J.D.16
Hirmand, M.17
Selby, B.18
Seely, L.19
De Bono, J.S.20
more..
-
3
-
-
84930225081
-
Integrative clinical genomics of advanced prostate cancer
-
D. Robinson, E. M. Van Allen, Y.-M. Wu, N. Schultz, R. J. Lonigro, J.-M. Mosquera, B. Montgomery, M.-E. Taplin, C. C. Pritchard, G. Attard, H. Beltran, W. Abida, R. K. Bradley, J. Vinson, X. Cao, P. Vats, L. P. Kunju, M. Hussain, F. Y. Feng, S. A. Tomlins, K. A. Cooney, D. C. Smith, C. Brennan, J. Siddiqui, R. Mehra, Y. Chen, D. E. Rathkopf, M. J. Morris, S. B. Solomon, J. C. Durack, V. E. Reuter, A. Gopalan, J. Gao, M. Loda, R. T. Lis, M. Bowden, S. P. Balk, G. Gaviola, C. Sougnez, M. Gupta, E. Y. Yu, E. A. Mostaghel, H. H. Cheng, H. Mulcahy, L. D. True, S. R. Plymate, H. Dvinge, R. Ferraldeschi, P. Flohr, S. Miranda, Z. Zafeiriou, N. Tunariu, J. Mateo, R. Perez-Lopez, F. Demichelis, B. D. Robinson, M. Schiffman, D. M. Nanus, S. T. Tagawa, A. Sigaras, K. W. Eng, O. Elemento, A. Sboner, E. I. Heath, H. I. Scher, K. J. Pienta, P. Kantoff, J. S. de Bono, M. A. Rubin, P. S. Nelson, L. A. Garraway, C. L. Sawyers, A. M. Chinnaiyan, Integrative clinical genomics of advanced prostate cancer. Cell 161, 1215-1228 (2015).
-
(2015)
Cell
, vol.161
, pp. 1215-1228
-
-
Robinson, D.1
Van Allen, E.M.2
Wu, Y.-M.3
Schultz, N.4
Lonigro, R.J.5
Mosquera, J.-M.6
Montgomery, B.7
Taplin, M.-E.8
Pritchard, C.C.9
Attard, G.10
Beltran, H.11
Abida, W.12
Bradley, R.K.13
Vinson, J.14
Cao, X.15
Vats, P.16
Kunju, L.P.17
Hussain, M.18
Feng, F.Y.19
Tomlins, S.A.20
Cooney, K.A.21
Smith, D.C.22
Brennan, C.23
Siddiqui, J.24
Mehra, R.25
Chen, Y.26
Rathkopf, D.E.27
Morris, M.J.28
Solomon, S.B.29
Durack, J.C.30
Reuter, V.E.31
Gopalan, A.32
Gao, J.33
Loda, M.34
Lis, R.T.35
Bowden, M.36
Balk, S.P.37
Gaviola, G.38
Sougnez, C.39
Gupta, M.40
Yu, E.Y.41
Mostaghel, E.A.42
Cheng, H.H.43
Mulcahy, H.44
True, L.D.45
Plymate, S.R.46
Dvinge, H.47
Ferraldeschi, R.48
Flohr, P.49
Miranda, S.50
Zafeiriou, Z.51
Tunariu, N.52
Mateo, J.53
Perez-Lopez, R.54
Demichelis, F.55
Robinson, B.D.56
Schiffman, M.57
Nanus, D.M.58
Tagawa, S.T.59
Sigaras, A.60
Eng, K.W.61
Elemento, O.62
Sboner, A.63
Heath, E.I.64
Scher, H.I.65
Pienta, K.J.66
Kantoff, P.67
De Bono, J.S.68
Rubin, M.A.69
Nelson, P.S.70
Garraway, L.A.71
Sawyers, C.L.72
Chinnaiyan, A.M.73
more..
-
4
-
-
84994777514
-
Whole-exome sequencing of metastatic cancer and biomarkers of treatment response
-
H. Beltran, K. Eng, J. M. Mosquera, A. Sigaras, A. Romanel, H. Rennert, M. Kossai, C. Pauli, B. Faltas, J. Fontugne, K. Park, J. Banfelder, D. Prandi, N. Madhukar, T. Zhang, J. Padilla, N. Greco, T. J. McNary, E. Herrscher, D. Wilkes, T. Y. MacDonald, H. Xue, V. Vacic, A.-K. Emde, D. Oschwald, A. Y. Tan, Z. Chen, C. Collins, M. E. Gleave, Y. Wang, D. Chakravarty, M. Schiffman, R. Kim, F. Campagne, B. D. Robinson, D. M. Nanus, S. T. Tagawa, J. Z. Xiang, A. Smogorzewska, F. Demichelis, D. S. Rickman, A. Sboner, O. Elemento, M. A. Rubin, Whole-exome sequencing of metastatic cancer and biomarkers of treatment response. JAMA Oncol. 1, 466-474 (2015).
-
(2015)
JAMA Oncol.
, vol.1
, pp. 466-474
-
-
Beltran, H.1
Eng, K.2
Mosquera, J.M.3
Sigaras, A.4
Romanel, A.5
Rennert, H.6
Kossai, M.7
Pauli, C.8
Faltas, B.9
Fontugne, J.10
Park, K.11
Banfelder, J.12
Prandi, D.13
Madhukar, N.14
Zhang, T.15
Padilla, J.16
Greco, N.17
McNary, T.J.18
Herrscher, E.19
Wilkes, D.20
MacDonald, T.Y.21
Xue, H.22
Vacic, V.23
Emde, A.-K.24
Oschwald, D.25
Tan, A.Y.26
Chen, Z.27
Collins, C.28
Gleave, M.E.29
Wang, Y.30
Chakravarty, D.31
Schiffman, M.32
Kim, R.33
Campagne, F.34
Robinson, B.D.35
Nanus, D.M.36
Tagawa, S.T.37
Xiang, J.Z.38
Smogorzewska, A.39
Demichelis, F.40
Rickman, D.S.41
Sboner, A.42
Elemento, O.43
Rubin, M.A.44
more..
-
5
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
W. Pao, V. A. Miller, K. A. Politi, G. J. Riely, R. Somwar, M. F. Zakowski, M. G. Kris, H. Varmus, Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLOS Med. 2, e73 (2005).
-
(2005)
PLOS Med.
, vol.2
, pp. e73
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
Kris, M.G.7
Varmus, H.8
-
6
-
-
84928405167
-
The evolutionary history of lethal metastatic prostate cancer
-
G. Gundem, P. Van Loo, B. Kremeyer, L. B. Alexandrov, J. M. Tubio, E. Papaemmanuil, D. S. Brewer, H. M. Kallio, G. Högnäs, M. Annala, K. Kivinummi, V. Goody, C. Latimer, S. O'Meara, K. J. Dawson, W. Isaacs, M. R. Emmert-Buck, M. Nykter, C. Foster, Z. Kote-Jarai, D. Easton, H. C. Whitaker; ICGC Prostate UK Group, D. E. Neal, C. S. Cooper, R. A. Eeles, T. Visakorpi, P. J. Campbell, U. McDermott, D. C. Wedge, G. S. Bova, The evolutionary history of lethal metastatic prostate cancer. Nature 520, 353-357 (2015).
-
(2015)
Nature
, vol.520
, pp. 353-357
-
-
Gundem, G.1
Van Loo, P.2
Kremeyer, B.3
Alexandrov, L.B.4
Tubio, J.M.5
Papaemmanuil, E.6
Brewer, D.S.7
Kallio, H.M.8
Högnäs, G.9
Annala, M.10
Kivinummi, K.11
Goody, V.12
Latimer, C.13
O'Meara, S.14
Dawson, K.J.15
Isaacs, W.16
Emmert-Buck, M.R.17
Nykter, M.18
Foster, C.19
Kote-Jarai, Z.20
Easton, D.21
Whitaker, H.C.22
Neal, D.E.23
Cooper, C.S.24
Eeles, R.A.25
Visakorpi, T.26
Campbell, P.J.27
McDermott, U.28
Wedge, D.C.29
Bova, G.S.30
more..
-
7
-
-
84896371874
-
Detection of circulating tumor DNA in early- and late-stage human malignancies
-
C. Bettegowda, M. Sausen, R. J. Leary, I. Kinde, Y. Wang, N. Agrawal, B. R. Bartlett, H. Wang, B. Luber, R. M. Alani, E. S. Antonarakis, N. S. Azad, A. Bardelli, H. Brem, J. L. Cameron, C. C. Lee, L. A. Fecher, G. L. Gallia, P. Gibbs, D. Le, R. L. Giuntoli, M. Goggins, M. D. Hogarty, M. Holdhoff, S.-M. Hong, Y. Jiao, H. H. Juhl, J. J. Kim, G. Siravegna, D. A. Laheru, C. Lauricella, M. Lim, E. J. Lipson, S. K. N. Marie, G. J. Netto, K. S. Oliner, A. Olivi, L. Olsson, G. J. Riggins, A. Sartore-Bianchi, K. Schmidt, L. M. Shih, S. M. Oba-Shinjo, S. Siena, D. Theodorescu, J. Tie, T. T. Harkins, S. Veronese, T.-L. Wang, J. D. Weingart, C. L. Wolfgang, L. D. Wood, D. Xing, R. H. Hruban, J. Wu, P. J. Allen, C. M. Schmidt, M. A. Choti, V. E. Velculescu, K. W. Kinzler, B. Vogelstein, N. Papadopoulos, L. A. Diaz Jr., Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci. Transl. Med. 6, 224ra224 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Bettegowda, C.1
Sausen, M.2
Leary, R.J.3
Kinde, I.4
Wang, Y.5
Agrawal, N.6
Bartlett, B.R.7
Wang, H.8
Luber, B.9
Alani, R.M.10
Antonarakis, E.S.11
Azad, N.S.12
Bardelli, A.13
Brem, H.14
Cameron, J.L.15
Lee, C.C.16
Fecher, L.A.17
Gallia, G.L.18
Gibbs, P.19
Le, D.20
Giuntoli, R.L.21
Goggins, M.22
Hogarty, M.D.23
Holdhoff, M.24
Hong, S.-M.25
Jiao, Y.26
Juhl, H.H.27
Kim, J.J.28
Siravegna, G.29
Laheru, D.A.30
Lauricella, C.31
Lim, M.32
Lipson, E.J.33
Marie, S.K.N.34
Netto, G.J.35
Oliner, K.S.36
Olivi, A.37
Olsson, L.38
Riggins, G.J.39
Sartore-Bianchi, A.40
Schmidt, K.41
Shih, L.M.42
Oba-Shinjo, S.M.43
Siena, S.44
Theodorescu, D.45
Tie, J.46
Harkins, T.T.47
Veronese, S.48
Wang, T.-L.49
Weingart, J.D.50
Wolfgang, C.L.51
Wood, L.D.52
Xing, D.53
Hruban, R.H.54
Wu, J.55
Allen, P.J.56
Schmidt, C.M.57
Choti, M.A.58
Velculescu, V.E.59
Kinzler, K.W.60
Vogelstein, B.61
Papadopoulos, N.62
Diaz, L.A.63
more..
-
8
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
S.-J. Dawson, D. W. Y. Tsui, M. Murtaza, H. Biggs, O. M. Rueda, S.-F. Chin, M. J. Dunning, D. Gale, T. Forshew, B. Mahler-Araujo, S. Rajan, S. Humphray, J. Becq, D. Halsall, M. Wallis, D. Bentley, C. Caldas, N. Rosenfeld, Analysis of circulating tumor DNA to monitor metastatic breast cancer. N. Engl. J. Med. 368, 1199-1209 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1199-1209
-
-
Dawson, S.-J.1
Tsui, D.W.Y.2
Murtaza, M.3
Biggs, H.4
Rueda, O.M.5
Chin, S.-F.6
Dunning, M.J.7
Gale, D.8
Forshew, T.9
Mahler-Araujo, B.10
Rajan, S.11
Humphray, S.12
Becq, J.13
Halsall, D.14
Wallis, M.15
Bentley, D.16
Caldas, C.17
Rosenfeld, N.18
-
9
-
-
84936748494
-
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
-
G. Siravegna, B. Mussolin, M. Buscarino, G. Corti, A. Cassingena, G. Crisafulli, A. Ponzetti, C. Cremolini, A. Amatu, C. Lauricella, S. Lamba, S. Hobor, A. Avallone, E. Valtorta, G. Rospo, E. Medico, V. Motta, C. Antoniotti, F. Tatangelo, B. Bellosillo, S. Veronese, A. Budillon, C. Montagut, P. Racca, S. Marsoni, A. Falcone, R. B. Corcoran, F. Di Nicolantonio, F. Loupakis, S. Siena, A. Sartore-Bianchi, A. Bardelli, Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients. Nat. Med. 21, 795-801 (2015).
-
(2015)
Nat. Med.
, vol.21
, pp. 795-801
-
-
Siravegna, G.1
Mussolin, B.2
Buscarino, M.3
Corti, G.4
Cassingena, A.5
Crisafulli, G.6
Ponzetti, A.7
Cremolini, C.8
Amatu, A.9
Lauricella, C.10
Lamba, S.11
Hobor, S.12
Avallone, A.13
Valtorta, E.14
Rospo, G.15
Medico, E.16
Motta, V.17
Antoniotti, C.18
Tatangelo, F.19
Bellosillo, B.20
Veronese, S.21
Budillon, A.22
Montagut, C.23
Racca, P.24
Marsoni, S.25
Falcone, A.26
Corcoran, R.B.27
Di Nicolantonio, F.28
Loupakis, F.29
Siena, S.30
Sartore-Bianchi, A.31
Bardelli, A.32
more..
-
10
-
-
84907285681
-
Tumor clone dynamics in lethal prostate cancer
-
S. Carreira, A. Romanel, J. Goodall, E. Grist, R. Ferraldeschi, S. Miranda, D. Prandi, D. Lorente, J.-S. Frenel, C. Pezaro, A. Omlin, D. N. Rodrigues, P. Flohr, N. Tunariu, J. S. de Bono, F. Demichelis, G. Attard, Tumor clone dynamics in lethal prostate cancer. Sci. Transl. Med. 6, 254ra125 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Carreira, S.1
Romanel, A.2
Goodall, J.3
Grist, E.4
Ferraldeschi, R.5
Miranda, S.6
Prandi, D.7
Lorente, D.8
Frenel, J.-S.9
Pezaro, C.10
Omlin, A.11
Rodrigues, D.N.12
Flohr, P.13
Tunariu, N.14
De Bono, J.S.15
Demichelis, F.16
Attard, G.17
-
11
-
-
84875824898
-
Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing
-
E. Heitzer, P. Ulz, J. Belic, S. Gutschi, F. Quehenberger, K. Fischereder, T. Benezeder, M. Auer, C. Pischler, S. Mannweiler, M. Pichler, F. Eisner, M. Haeusler, S. Riethdorf, K. Pantel, H. Samonigg, G. Hoefler, H. Augustin, J. B. Geigl, M. R. Speicher, Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing. Genome Med. 5, 30 (2013).
-
(2013)
Genome Med.
, vol.5
, pp. 30
-
-
Heitzer, E.1
Ulz, P.2
Belic, J.3
Gutschi, S.4
Quehenberger, F.5
Fischereder, K.6
Benezeder, T.7
Auer, M.8
Pischler, C.9
Mannweiler, S.10
Pichler, M.11
Eisner, F.12
Haeusler, M.13
Riethdorf, S.14
Pantel, K.15
Samonigg, H.16
Hoefler, G.17
Augustin, H.18
Geigl, J.B.19
Speicher, M.R.20
more..
-
12
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
-
M. Murtaza, S.-J. Dawson, D. W. Y. Tsui, D. Gale, T. Forshew, A. M. Piskorz, C. Parkinson, S.-F. Chin, Z. Kingsbury, A. S. C. Wong, F. Marass, S. Humphray, J. Hadfield, D. Bentley, T. M. Chin, J. D. Brenton, C. Caldas, N. Rosenfeld, Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 497, 108-112 (2013).
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
Dawson, S.-J.2
Tsui, D.W.Y.3
Gale, D.4
Forshew, T.5
Piskorz, A.M.6
Parkinson, C.7
Chin, S.-F.8
Kingsbury, Z.9
Wong, A.S.C.10
Marass, F.11
Humphray, S.12
Hadfield, J.13
Bentley, D.14
Chin, T.M.15
Brenton, J.D.16
Caldas, C.17
Rosenfeld, N.18
-
13
-
-
0033767930
-
Androgen receptor gene amplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer
-
C. Palmberg, P. Koivisto, L. Kakkola, T. L. J. Tammela, O. P. Kallioniemi, T. Visakorpi, Androgen receptor gene amplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer. J. Urol. 164, 1992-1995 (2000).
-
(2000)
J. Urol.
, vol.164
, pp. 1992-1995
-
-
Palmberg, C.1
Koivisto, P.2
Kakkola, L.3
Tammela, T.L.J.4
Kallioniemi, O.P.5
Visakorpi, T.6
-
14
-
-
0029011116
-
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
-
M.-E. Taplin, G. J. Bubley, T. D. Shuster, M. E. Frantz, A. E. Spooner, G. K. Ogata, H. N. Keer, S. P. Balk, Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N. Engl. J. Med. 332, 1393-1398 (1995).
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 1393-1398
-
-
Taplin, M.-E.1
Bubley, G.J.2
Shuster, T.D.3
Frantz, M.E.4
Spooner, A.E.5
Ogata, G.K.6
Keer, H.N.7
Balk, S.P.8
-
15
-
-
0028944138
-
In vivo amplification of the androgen receptor gene and progression of human prostate cancer
-
T. Visakorpi, E. Hyytinen, P. Koivisto, M. Tanner, R. Keinänen, C. Palmberg, A. Palotie, T. Tammela, J. Isola, O.-P. Kallioniemi, In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat. Genet. 9, 401-406 (1995).
-
(1995)
Nat. Genet.
, vol.9
, pp. 401-406
-
-
Visakorpi, T.1
Hyytinen, E.2
Koivisto, P.3
Tanner, M.4
Keinänen, R.5
Palmberg, C.6
Palotie, A.7
Tammela, T.8
Isola, J.9
Kallioniemi, O.-P.10
-
16
-
-
84964314022
-
Unraveling the clonal hierarchy of somatic genomic aberrations
-
D. Prandi, S. C. Baca, A. Romanel, C. E. Barbieri, J.-M. Mosquera, J. Fontugne, H. Beltran, A. Sboner, L. A. Garraway, M. A. Rubin, F. Demichelis, Unraveling the clonal hierarchy of somatic genomic aberrations. Genome Biol. 15, 439 (2014).
-
(2014)
Genome Biol.
, vol.15
, pp. 439
-
-
Prandi, D.1
Baca, S.C.2
Romanel, A.3
Barbieri, C.E.4
Mosquera, J.-M.5
Fontugne, J.6
Beltran, H.7
Sboner, A.8
Garraway, L.A.9
Rubin, M.A.10
Demichelis, F.11
-
17
-
-
0242609180
-
Sequence divergence, functional constraint, and selection in protein evolution
-
J. C. Fay, C.-I. Wu, Sequence divergence, functional constraint, and selection in protein evolution. Annu. Rev. Genomics Hum. Genet. 4, 213-235 (2003).
-
(2003)
Annu. Rev. Genomics Hum. Genet.
, vol.4
, pp. 213-235
-
-
Fay, J.C.1
Wu, C.-I.2
-
18
-
-
0036720020
-
The ka/Ks ratio: Diagnosing the form of sequence evolution
-
L. D. Hurst, The Ka/Ks ratio: Diagnosing the form of sequence evolution. Trends Genet. 18, 486-487 (2002).
-
(2002)
Trends Genet.
, vol.18
, pp. 486-487
-
-
Hurst, L.D.1
-
19
-
-
84927655173
-
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors
-
E. J. Chen, A. G. Sowalsky, S. Gao, C. Cai, O. Voznesensky, R. Schaefer, M. Loda, L. D. True, H. Ye, P. Troncoso, R. L. Lis, P. W. Kantoff, R. B. Montgomery, P. S. Nelson, G. J. Bubley, S. P. Balk, M.-E. Taplin, Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors. Clin. Cancer Res. 21, 1273-1280 (2015).
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 1273-1280
-
-
Chen, E.J.1
Sowalsky, A.G.2
Gao, S.3
Cai, C.4
Voznesensky, O.5
Schaefer, R.6
Loda, M.7
True, L.D.8
Ye, H.9
Troncoso, P.10
Lis, R.L.11
Kantoff, P.W.12
Montgomery, R.B.13
Nelson, P.S.14
Bubley, G.J.15
Balk, S.P.16
Taplin, M.-E.17
-
20
-
-
84929292191
-
Circulating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone
-
S. Salvi, V. Casadio, V. Conteduca, S. L. Burgio, C. Menna, E. Bianchi, L. Rossi, E. Carretta, C. Masini, D. Amadori, D. Calistri, G. Attard, U. De Giorgi, Circulating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone. Br. J. Cancer 112, 1717-1724 (2015).
-
(2015)
Br. J. Cancer
, vol.112
, pp. 1717-1724
-
-
Salvi, S.1
Casadio, V.2
Conteduca, V.3
Burgio, S.L.4
Menna, C.5
Bianchi, E.6
Rossi, L.7
Carretta, E.8
Masini, C.9
Amadori, D.10
Calistri, D.11
Attard, G.12
De Giorgi, U.13
-
21
-
-
84933510527
-
Androgen receptor gene aberrations in circulating cell-free DNA: Biomarkers of therapeutic resistance in castration-resistant prostate cancer
-
A. A. Azad, S. V. Volik, A. W. Wyatt, A. Haegert, S. Le Bihan, R. H. Bell, S. A. Anderson, B. McConeghy, R. Shukin, J. Bazov, J. Youngren, P. Paris, G. Thomas, E. J. Small, Y. Wang, M. E. Gleave, C. C. Collins, K. N. Chi, Androgen receptor gene aberrations in circulating cell-free DNA: Biomarkers of therapeutic resistance in castration-resistant prostate cancer. Clin. Cancer Res. 21, 2315-2324 (2015).
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 2315-2324
-
-
Azad, A.A.1
Volik, S.V.2
Wyatt, A.W.3
Haegert, A.4
Le Bihan, S.5
Bell, R.H.6
Anderson, S.A.7
McConeghy, B.8
Shukin, R.9
Bazov, J.10
Youngren, J.11
Paris, P.12
Thomas, G.13
Small, E.J.14
Wang, Y.15
Gleave, M.E.16
Collins, C.C.17
Chi, K.N.18
-
22
-
-
84907057471
-
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
-
E. S. Antonarakis, C. Lu, H. Wang, B. Luber, M. Nakazawa, J. C. Roeser, Y. Chen, T. A. Mohammad, Y. Chen, H. L. Fedor, T. L. Lotan, Q. Zheng, A. M. De Marzo, J. T. Isaacs, W. B. Isaacs, R. Nadal, C. J. Paller, S. R. Denmeade, M. A. Carducci, M. A. Eisenberger, J. Luo, AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N. Engl. J. Med. 371, 1028-1038 (2014).
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 1028-1038
-
-
Antonarakis, E.S.1
Lu, C.2
Wang, H.3
Luber, B.4
Nakazawa, M.5
Roeser, J.C.6
Chen, Y.7
Mohammad, T.A.8
Chen, Y.9
Fedor, H.L.10
Lotan, T.L.11
Zheng, Q.12
De Marzo, A.M.13
Isaacs, J.T.14
Isaacs, W.B.15
Nadal, R.16
Paller, C.J.17
Denmeade, S.R.18
Carducci, M.A.19
Eisenberger, M.A.20
Luo, J.21
more..
-
23
-
-
85068160367
-
Detecting predictive androgen receptor modifications in circulating prostate cancer cells
-
J. Steinestel, M. Luedeke, A. Arndt, T. J. Schnoeller, J. K. Lennerz, C. Wurm, C. Maier, M. V. Cronauer, K. Steinestel, A. J. Schrader, Detecting predictive androgen receptor modifications in circulating prostate cancer cells. Oncotarget 10.18632/oncotarget.3925 (2015).
-
(2015)
Oncotarget
-
-
Steinestel, J.1
Luedeke, M.2
Arndt, A.3
Schnoeller, T.J.4
Lennerz, J.K.5
Wurm, C.6
Maier, C.7
Cronauer, M.V.8
Steinestel, K.9
Schrader, A.J.10
-
24
-
-
0035328474
-
Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer
-
M. J. Linja, K. J. Savinainen, O. R. Saramäki, T. L. J. Tammela, R. L. Vessella, T. Visakorpi, Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer. Cancer Res. 61, 3550-3555 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 3550-3555
-
-
Linja, M.J.1
Savinainen, K.J.2
Saramäki, O.R.3
Tammela, T.L.J.4
Vessella, R.L.5
Visakorpi, T.6
-
25
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
C. D. Chen, D. S. Welsbie, C. Tran, S. H. Baek, R. Chen, R. Vessella, M. G. Rosenfeld, C. L. Sawyers, Molecular determinants of resistance to antiandrogen therapy. Nat. Med. 10, 33-39 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vessella, R.6
Rosenfeld, M.G.7
Sawyers, C.L.8
-
26
-
-
70350244512
-
Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens
-
K. K. Waltering, M. A. Helenius, B. Sahu, V. Manni, M. J. Linja, O. A. Jänne, T. Visakorpi, Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens. Cancer Res. 69, 8141-8149 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 8141-8149
-
-
Waltering, K.K.1
Helenius, M.A.2
Sahu, B.3
Manni, V.4
Linja, M.J.5
Jänne, O.A.6
Visakorpi, T.7
-
27
-
-
41949104346
-
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the prostate cancer clinical trials working group
-
H. I. Scher, S. Halabi, I. Tannock, M. Morris, C. N. Sternberg, M. A. Carducci, M. A. Eisenberger, C. Higano, G. J. Bubley, R. Dreicer, D. Petrylak, P. Kantoff, E. Basch, W. K. Kelly, W. D. Figg, E. J. Small, T. M. Beer, G. Wilding, A. Martin, M. Hussain, Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group. J. Clin. Oncol. 26, 1148-1159 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
Morris, M.4
Sternberg, C.N.5
Carducci, M.A.6
Eisenberger, M.A.7
Higano, C.8
Bubley, G.J.9
Dreicer, R.10
Petrylak, D.11
Kantoff, P.12
Basch, E.13
Kelly, W.K.14
Figg, W.D.15
Small, E.J.16
Beer, T.M.17
Wilding, G.18
Martin, A.19
Hussain, M.20
more..
-
28
-
-
84872078210
-
Abiraterone in meta-static prostate cancer without previous chemotherapy
-
C. J. Ryan, M. R. Smith, J. S. de Bono, A. Molina, C. J. Logothetis, P. de Souza, K. Fizazi, P. Mainwaring, J. M. Piulats, S. Ng, J. Carles, P. F. A. Mulders, E. Basch, E. J. Small, F. Saad, D. Schrijvers, H. Van Poppel, S. D. Mukherjee, H. Suttmann, W. R. Gerritsen, T. W. Flaig, D. J. George, E. Y. Yu, E. Efstathiou, A. Pantuck, E. Winquist, C. S. Higano, M.-E. Taplin, Y. Park, T. Kheoh, T. Griffin, H. I. Scher, D. E. Rathkopf; COU-AA-302 Investigators, Abiraterone in meta-static prostate cancer without previous chemotherapy. N. Engl. J. Med. 368, 138-148 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
Molina, A.4
Logothetis, C.J.5
De Souza, P.6
Fizazi, K.7
Mainwaring, P.8
Piulats, J.M.9
Ng, S.10
Carles, J.11
Mulders, P.F.A.12
Basch, E.13
Small, E.J.14
Saad, F.15
Schrijvers, D.16
Van Poppel, H.17
Mukherjee, S.D.18
Suttmann, H.19
Gerritsen, W.R.20
Flaig, T.W.21
George, D.J.22
Yu, E.Y.23
Efstathiou, E.24
Pantuck, A.25
Winquist, E.26
Higano, C.S.27
Taplin, M.-E.28
Park, Y.29
Kheoh, T.30
Griffin, T.31
Scher, H.I.32
Rathkopf, D.E.33
more..
-
29
-
-
84928166234
-
ASEQ: Fast allele-specific studies from next-generation sequencing data
-
A. Romanel, S. Lago, D. Prandi, A. Sboner, F. Demichelis, ASEQ: Fast allele-specific studies from next-generation sequencing data. BMC Med. Genomics 8, 9 (2015).
-
(2015)
BMC Med. Genomics
, vol.8
, pp. 9
-
-
Romanel, A.1
Lago, S.2
Prandi, D.3
Sboner, A.4
Demichelis, F.5
|