Neural stem cell transplantation at critical period improves learning and memory through restoring synaptic impairment in Alzheimer's disease mouse model

Cell Death and Disease

Volumn 6, Issue 6, 2015, Pages

  Kim, J A ^a   Ha, S ^b   Shin, K Y ^a   Kim, S ^b   Lee, K J ^c   Chong, Y H ^d   Chang, K A ^b   Suh, Y H ^a,c  

^a Seoul National University   (South Korea)

^b Gachon University   (South Korea)

^c Korea Brain Research Institute (KBRI)   (South Korea)

^d Ewha Womans University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MICROTUBULE ASSOCIATED PROTEIN 2; NERVE CELL ADHESION MOLECULE; POSTSYNAPTIC DENSITY PROTEIN 95; TAU PROTEIN; CYTOKINE;

ADULT; ALZHEIMER DISEASE; AMNESIA; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE RELEASE; ENTORHINAL CORTEX; FEMALE; FETAL STEM CELL; FETUS; FRONTAL CORTEX; HIPPOCAMPUS; MEMORY; MICROGLIA; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PYRIFORM CORTEX; SPATIAL LEARNING; SYNAPSE; TG2576 MOUSE; UPREGULATION; ANIMAL; BIOLOGICAL THERAPY; BRAIN; C57BL MOUSE; CELL CULTURE; COGNITION DISORDERS; DISEASE MODEL; MAZE TEST; MEMORY DISORDERS; METABOLISM; NEURAL STEM CELL; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SECRETION (PROCESS); SURGERY; TRANSPLANTATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; COGNITION DISORDERS; CYTOKINES; DISEASE MODELS, ANIMAL; MAZE LEARNING; MEMORY; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; NEURAL STEM CELLS; NEUROGENESIS;

EID: 84989315893     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.138     Document Type: Article

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