Microfluidic diffusion analysis of the sizes and interactions of proteins under native solution conditions

ACS Nano

Volumn 10, Issue 1, 2016, Pages 333-341

  Arosio, Paolo ^a   Müller, Thomas ^a,b   Rajah, Luke ^a   Yates, Emma V ^a   Aprile, Francesco A ^a   Zhang, Yingbo ^a   Cohen, Samuel I A ^a   White, Duncan A ^a   Herling, Therese W ^a   De Genst, Erwin J ^a   Linse, Sara ^c   Vendruscolo, Michele ^a   Dobson, Christopher M ^a   Knowles, Tuomas P J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b FLUIDIC ANALYTICS LTD   (United Kingdom)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Diffusion; Immunoassay; Interactions; Polydispersity; Proteins; Size distribution

Indexed keywords

BEAM PLASMA INTERACTIONS; BIOMOLECULES; DIFFUSION; IMMUNOLOGY; MIXTURES; POLYDISPERSITY; PROTEINS; SIZE DISTRIBUTION;

DIFFUSION ANALYSIS; GLOBAL ANALYSIS; HYDRODYNAMIC RADIUS; IMMUNOASSAY; MICROFLUIDIC PLATFORMS; MOLECULAR SCIENCE; SOLUTION CONDITIONS; SPECIFIC INTERACTION;

MICROFLUIDICS;

ALPHA SYNUCLEIN; BOVINE SERUM ALBUMIN; FLUORESCENT DYE; GLUCAGON; HEAT SHOCK PROTEIN 70; NANOBODY; PHTHALALDEHYDE; SOLUTION AND SOLUBILITY; WATER;

ANIMAL; BOVINE; CHEMISTRY; DEVICES; DIFFUSION; HUMAN; HYDRODYNAMICS; IMMUNOASSAY; MICROFLUIDIC ANALYSIS; MICROFLUIDICS; MOLECULAR WEIGHT; PROCEDURES; SOLUTION AND SOLUBILITY; STAINING;

ALPHA-SYNUCLEIN; ANIMALS; CATTLE; DIFFUSION; FLUORESCENT DYES; GLUCAGON; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYDRODYNAMICS; IMMUNOASSAY; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; MOLECULAR WEIGHT; O-PHTHALALDEHYDE; SERUM ALBUMIN, BOVINE; SINGLE-DOMAIN ANTIBODIES; SOLUTIONS; STAINING AND LABELING; WATER;

EID: 84989315217     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b04713     Document Type: Article

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