Identification of thyroid hormone receptor active compounds using a quantitative high-throughput screening platform

Current Chemical Genomics and Translational Medicine

Volumn 8, Issue 1, 2014, Pages 36-46

  Freitas, Jaime ^a,e   Miller, Nicole ^b   Mengeling, Brenda J ^c   Xia, Menghang ^b   Huang, Ruili ^b   Houck, Keith ^d   Rietjens, Ivonne M C M ^a   Furlow, J David ^c   Murk, Albertinka J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e UNIVERSITY OF PORTO   (Portugal)

Author keywords

Endocrine disruption; Pituitary cells; Quantitative high throughput screening; Reporter gene assay; Retinoid X receptor; Thyroid hormone receptor

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; 2,6 DI TERT BUTYL 4 (3 HYDROXY 2,2 DIMETHYLPROPYL)PHENOL; ACETYLPHENYLHYDRAZINE; FLUOROURACIL; ISOTRETINOIN; LIOTHYRONINE; RETINAL; RETINOIC ACID; RETINOID X RECEPTOR; THYROID HORMONE RECEPTOR; THYROXINE; TRANILAST;

ARTICLE; CELL VIABILITY ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENCY; GENE EXPRESSION REGULATION; HIGH THROUGHPUT SCREENING; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; PRIORITY JOURNAL; REPORTER GENE;

EID: 84989270930     PISSN: None     EISSN: 22139885     Source Type: Journal    
DOI: 10.2174/2213988501408010036     Document Type: Article

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