Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay

Toxicology in Vitro

Volumn 25, Issue 1, 2011, Pages 257-266

  Freitas, Jaime ^a   Cano, Patricia ^a   Craig Veit, Christina ^b   Goodson, Michael L ^b   David Furlow, J ^b   Murk, Albertinka J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amiodarone; Bisphenol A; Endocrine disruption; PBDE; PCB metabolite; Thyroid hormone receptor

Indexed keywords

2,2 BIS(4 HYDROXY 3,5 DICHLOROPHENYL)PROPANE; 4,4' ISOPROPYLIDENEDIPHENOL; 4,4' PROPANE 2,2 DIYLBIS(2,6 DIBROMOPHENOL); ACETIC ACID DERIVATIVE; AMIODARONE; ARSENITE SODIUM; ENDOCRINE DISRUPTOR; FIREFLY LUCIFERASE; HORMONE RECEPTOR AFFECTING AGENT; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; LIOTHYRONINE; POLYBROMINATED DIPHENYL ETHER; POLYCHLORINATED BIPHENYL; RESAZURIN; TETRAIODOTHYROACETIC ACID; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR BLOCKING AGENT; THYROID HORMONE RECEPTOR STIMULATING AGENT; THYROXINE; TIRATRICOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOASSAY; CELL PROLIFERATION; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EXPRESSION VECTOR; GENE EXPRESSION; GENE INDUCTION; HIGH THROUGHPUT SCREENING; IC 50; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; REPORTER GENE; STABLE TRANSFECTION; TUMOR CELL LINE;

ANIMALS; CELL COUNT; CELL LINE, TUMOR; CELL SURVIVAL; ENDOCRINE DISRUPTORS; ENVIRONMENTAL POLLUTANTS; GENES, REPORTER; HIGH-THROUGHPUT SCREENING ASSAYS; LIMIT OF DETECTION; LUCIFERASES, FIREFLY; MICROCHEMISTRY; PLASMIDS; RATS; RECEPTORS, THYROID HORMONE; REPRODUCIBILITY OF RESULTS; RESPONSE ELEMENTS; THYROXINE; TOXICITY TESTS; TRANSFECTION; TRIIODOTHYRONINE;

RATTUS;

EID: 78650522817     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.08.013     Document Type: Article

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