-
1
-
-
84920887662
-
Biomarkers for personalized oncology: Recent advances and future challenges
-
Kalia M. Biomarkers for personalized oncology: recent advances and future challenges. Metabolism 2015; 64: S16-21.
-
(2015)
Metabolism
, vol.64
, pp. S16-S21
-
-
Kalia, M.1
-
2
-
-
84989243447
-
-
(Accessed on 15th August 2015)
-
The website of Cancer Research UK, http: //www.cancerresearchuk. org2012 (Accessed on 15th August 2015).
-
(2012)
The Website of Cancer Research UK
-
-
-
3
-
-
84926457179
-
European cancer mortality predictions for the year 2015: Does lung cancer have the highest death rate in EU women?
-
Malvezzi M, Bertuccio P, Rosso T, et al. European cancer mortality predictions for the year 2015: does lung cancer have the highest death rate in EU women? Ann Oncol 2015; 26: 779-86.
-
(2015)
Ann Oncol
, vol.26
, pp. 779-786
-
-
Malvezzi, M.1
Bertuccio, P.2
Rosso, T.3
-
4
-
-
84875999574
-
Lung cancer in China: Challenges and interventions
-
She J, Yang P, Hong Q, Bai C. Lung cancer in China: challenges and interventions. Chest 2013; 143: 1117-26.
-
(2013)
Chest
, vol.143
, pp. 1117-1126
-
-
She, J.1
Yang, P.2
Hong, Q.3
Bai, C.4
-
5
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002; 346: 92-8.
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
-
8
-
-
84875937242
-
Genotyping and genomic profiling of non-small-cell lung cancer: Implications for current and future therapies
-
Li T, Kung HJ, Mack PC, Gandara DR. Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J Clin Oncol 2013; 31: 1039-49.
-
(2013)
J Clin Oncol
, vol.31
, pp. 1039-1049
-
-
Li, T.1
Kung, H.J.2
Mack, P.C.3
Gandara, D.R.4
-
9
-
-
84858448292
-
-
(Accessed on 15th August 2015)
-
The National Cancer Institute dictionary http: //www.cancer.gov/ dictionary?CdrD=56717.,(Accessed on 15th August 2015)
-
The National Cancer Institute Dictionary
-
-
-
10
-
-
79551563284
-
International association for the study of lung cancer/american thoracic society/ european respiratory society international multidisciplinary classification of lung adenocarcinoma
-
Travis WD, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/american thoracic society/ european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011; 6: 244-85.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 244-285
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
-
11
-
-
49049089802
-
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
-
Scagliotti GV, Parikh P, von Pawel J, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008; 26: 3543-51.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3543-3551
-
-
Scagliotti, G.V.1
Parikh, P.2
Von Pawel, J.3
-
12
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004; 22: 2184-91.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
13
-
-
33750700477
-
Erlotinib for frontline treatment of advanced non-small cell lung cancer: A phase II study
-
Giaccone G, Gallegos Ruiz M, et al. Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. Clin Cancer Res 2006; 12: 6049-55.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6049-6055
-
-
Giaccone, G.1
Gallegos Ruiz, M.2
-
14
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-32.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
-
15
-
-
1842509828
-
Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer
-
Miller VA, Kris MG, Shah N, et al. Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. J Clin Oncol 2004; 22: 1103-9.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1103-1109
-
-
Miller, V.A.1
Kris, M.G.2
Shah, N.3
-
16
-
-
69949162760
-
Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009; 361: 947-57.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
17
-
-
84856465513
-
Recent developments and future perspectives of personalized oncology
-
Grullich C, von Kalle C. Recent developments and future perspectives of personalized oncology. Onkologie 2012; 35 (Suppl 1): 4-7.
-
(2012)
Onkologie
, vol.35
, pp. 4-7
-
-
Grullich, C.1
Von Kalle, C.2
-
18
-
-
84901514004
-
Prognostic and predictive biomarkers: Tools in personalized oncology
-
Nalejska E, Maczynska E, Lewandowska MA. Prognostic and predictive biomarkers: tools in personalized oncology. Mol Diagn Ther 2014; 18: 273-84.
-
(2014)
Mol Diagn Ther
, vol.18
, pp. 273-284
-
-
Nalejska, E.1
Maczynska, E.2
Lewandowska, M.A.3
-
19
-
-
67649506174
-
Genetic prognostic and predictive markers in colorectal cancer
-
Walther A, Johnstone E, Swanton C, Midgley R, Tomlinson I, Kerr D. Genetic prognostic and predictive markers in colorectal cancer. Nat Rev Cancer 2009; 9: 489-99.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 489-499
-
-
Walther, A.1
Johnstone, E.2
Swanton, C.3
Midgley, R.4
Tomlinson, I.5
Kerr, D.6
-
20
-
-
80052829389
-
Tumour genetics and genomics to personalise cancer treatment
-
Voon PJ, Kong HL. Tumour genetics and genomics to personalise cancer treatment. Ann Acad Med Singapore 2011; 40: 362-8.
-
(2011)
Ann Acad Med Singapore
, vol.40
, pp. 362-368
-
-
Voon, P.J.1
Kong, H.L.2
-
21
-
-
0034124449
-
Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in nonsmall cell lung cancer
-
Ahrendt SA, Chow JT, Yang SC, et al. Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in nonsmall cell lung cancer. Cancer Res 2000; 60: 3155-9.
-
(2000)
Cancer Res
, vol.60
, pp. 3155-3159
-
-
Ahrendt, S.A.1
Chow, J.T.2
Yang, S.C.3
-
22
-
-
0034118679
-
P53 gene mutation and protein expression in operable non-small cell lung cancer in Poland
-
Niklinska W, Burzykowski T, Chyczewski L, et al. p53 gene mutation and protein expression in operable non-small cell lung cancer in Poland. Eur J Cancer Prev 2000; 9: 81-7.
-
(2000)
Eur J Cancer Prev
, vol.9
, pp. 81-87
-
-
Niklinska, W.1
Burzykowski, T.2
Chyczewski, L.3
-
23
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 2002; 110: 669-72.
-
(2002)
Cell
, vol.110
, pp. 669-672
-
-
Schlessinger, J.1
-
24
-
-
73149115248
-
Targeting the RET pathway in thyroid cancer
-
Wells SA, Jr., Santoro M. Targeting the RET pathway in thyroid cancer. Clin Cancer Res 2009; 15: 7119-23.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7119-7123
-
-
Wells, S.A.1
Santoro, M.2
-
25
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000; 19: 3159-67.
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
26
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
-
Tzahar E, Waterman H, Chen X, et al. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 1996; 16: 5276-87.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
-
27
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006; 7: 505-16.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
28
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000; 103: 211-25.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
29
-
-
3442890204
-
Role of HER receptors family in development and differentiation
-
Casalini P, Iorio MV, Galmozzi E, Menard S. Role of HER receptors family in development and differentiation. J Cell Physiol 2004; 200: 343-50.
-
(2004)
J Cell Physiol
, vol.200
, pp. 343-350
-
-
Casalini, P.1
Iorio, M.V.2
Galmozzi, E.3
Menard, S.4
-
30
-
-
84866861514
-
Where EGF receptors transmit their signals
-
Lill NL, Sever NI. Where EGF receptors transmit their signals. Sci Signal 2012; 5: pe41.
-
(2012)
Sci Signal
, vol.5
-
-
Lill, N.L.1
Sever, N.I.2
-
31
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R, Moran T, Queralt C, et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009; 361: 958-67.
-
(2009)
N Engl J Med
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
-
32
-
-
33846187218
-
Update on epidermal growth factor receptor mutations in non-small cell lung cancer
-
Riely GJ, Politi KA, Miller VA, Pao W. Update on epidermal growth factor receptor mutations in non-small cell lung cancer. Clin Cancer Res 2006; 12: 7232-41.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7232-7241
-
-
Riely, G.J.1
Politi, K.A.2
Miller, V.A.3
Pao, W.4
-
33
-
-
84873901211
-
The detection of EGFR mutations in patients with non-small cell lung cancer in selected molecular diagnostics centers in Poland
-
Krawczyk P RR, Powrozek T, Wojas-Krawczyk K, et al. The detection of EGFR mutations in patients with non-small cell lung cancer in selected molecular diagnostics centers in Poland. Pol J Cardio Thorac Surg 2012; 9: 431-8.
-
(2012)
Pol J Cardio Thorac Surg
, vol.9
, pp. 431-438
-
-
Krawczyk, P.1
Powrozek, T.2
Wojas-Krawczyk, K.3
-
34
-
-
84874234453
-
Analysis of EGFR mutation frequency and coexistence of KRAS and EGFR mutations using RT-PCR in lung adenocarcinoma: May a clinical and pathological model of a patient’s qualification for targeted therapy have an impact on time to obtain genetic results?
-
Lewandowska MA, Jozwicki W, Starzynski J, Kowalewski J. Analysis of EGFR mutation frequency and coexistence of KRAS and EGFR mutations using RT-PCR in lung adenocarcinoma: may a clinical and pathological model of a patient’s qualification for targeted therapy have an impact on time to obtain genetic results? Pol J Cardio Thorac Surg 2012; 9: 443-51.
-
(2012)
Pol J Cardio Thorac Surg
, vol.9
, pp. 443-451
-
-
Lewandowska, M.A.1
Jozwicki, W.2
Starzynski, J.3
Kowalewski, J.4
-
35
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005; 2: e73.
-
(2005)
Plos Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
36
-
-
40049099220
-
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
-
Yun CH, Mengwasser KE, Toms AV, et al. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci USA 2008; 105: 2070-5.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2070-2075
-
-
Yun, C.H.1
Mengwasser, K.E.2
Toms, A.V.3
-
37
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
38
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
39
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004; 101: 13306-11.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
40
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012; 13: 239-46.
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
41
-
-
84861976809
-
First-SIGNAL: First-line singleagent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung
-
Han JY, Park K, Kim SW, et al. First-SIGNAL: first-line singleagent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung. J Clin Oncol 2012; 30: 1122-8.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1122-1128
-
-
Han, J.Y.1
Park, K.2
Kim, S.W.3
-
42
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutationpositive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutationpositive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011; 12: 735-42.
-
(2011)
Lancet Oncol
, vol.12
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
-
43
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
-
Mitsudomi T, Morita S, Yatabe Y, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010; 11: 121-8.
-
(2010)
Lancet Oncol
, vol.11
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
-
44
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010; 362: 2380-8.
-
(2010)
N Engl J Med
, vol.362
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
-
45
-
-
45749120442
-
Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapynaive non-small-cell lung cancer receiving first-line gefitinib monotherapy
-
Yang CH, Yu CJ, Shih JY, et al. Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapynaive non-small-cell lung cancer receiving first-line gefitinib monotherapy. J Clin Oncol 2008; 26: 2745-53.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2745-2753
-
-
Yang, C.H.1
Yu, C.J.2
Shih, J.Y.3
-
46
-
-
84892880551
-
Epidermal growth factor receptor mutation analysis in previously unanalyzed histology samples and cytology samples from the phase III Iressa Pan-ASia Study (IPASS)
-
Yang JC, Wu YL, Chan V, et al. Epidermal growth factor receptor mutation analysis in previously unanalyzed histology samples and cytology samples from the phase III Iressa Pan-ASia Study (IPASS). Lung Cancer 2014; 83: 174-81.
-
(2014)
Lung Cancer
, vol.83
, pp. 174-181
-
-
Yang, J.C.1
Wu, Y.L.2
Chan, V.3
-
47
-
-
84878888082
-
First-line management of EGFRmutated advanced lung adenocarcinoma: Recent developments
-
Liao BC, Lin CC, Yang JC. First-line management of EGFRmutated advanced lung adenocarcinoma: recent developments. Drugs 2013; 73: 357-69.
-
(2013)
Drugs
, vol.73
, pp. 357-369
-
-
Liao, B.C.1
Lin, C.C.2
Yang, J.C.3
-
48
-
-
0032526729
-
Differential endocytic routing of homo-and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers
-
Lenferink AE, Pinkas-Kramarski R, van de Poll ML, et al. Differential endocytic routing of homo-and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers. EMBO J 1998; 17: 3385-97.
-
(1998)
EMBO J
, vol.17
, pp. 3385-3397
-
-
Lenferink, A.E.1
Pinkas-Kramarski, R.2
Van De Poll, M.L.3
-
49
-
-
84884605223
-
Symptom control and quality of life in LUX-Lung 3: A phase III study of afatinib or cisplatin/ pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations
-
Yang JC, Hirsh V, Schuler M, et al. Symptom control and quality of life in LUX-Lung 3: a phase III study of afatinib or cisplatin/ pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations. J Clin Oncol 2013; 31: 3342-50.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3342-3350
-
-
Yang, J.C.1
Hirsh, V.2
Schuler, M.3
-
50
-
-
84884736973
-
Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
-
Sequist LV, Yang JC, Yamamoto N, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol 2013; 31: 3327-34.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3327-3334
-
-
Sequist, L.V.1
Yang, J.C.2
Yamamoto, N.3
-
51
-
-
49149118719
-
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
-
Li D, Ambrogio L, Shimamura T, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene 2008; 27: 4702-11.
-
(2008)
Oncogene
, vol.27
, pp. 4702-4711
-
-
Li, D.1
Ambrogio, L.2
Shimamura, T.3
-
52
-
-
84867621201
-
Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker
-
Solca F, Dahl G, Zoephel A, et al. Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker. J Pharmacol Exp Ther 2012; 343: 342-50.
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 342-350
-
-
Solca, F.1
Dahl, G.2
Zoephel, A.3
-
53
-
-
51049123872
-
Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor
-
Gonzales AJ, Hook KE, Althaus IW, et al. Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor. Mol Cancer Ther 2008; 7: 1880-9.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1880-1889
-
-
Gonzales, A.J.1
Hook, K.E.2
Althaus, I.W.3
-
54
-
-
37549061078
-
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib
-
Engelman JA, Zejnullahu K, Gale CM, et al. PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib. Cancer Res 2007; 67: 11924-32.
-
(2007)
Cancer Res
, vol.67
, pp. 11924-11932
-
-
Engelman, J.A.1
Zejnullahu, K.2
Gale, C.M.3
-
55
-
-
72949092456
-
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
-
Zhou W, Ercan D, Chen L, et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature 2009; 462: 1070-4.
-
(2009)
Nature
, vol.462
, pp. 1070-1074
-
-
Zhou, W.1
Ercan, D.2
Chen, L.3
-
56
-
-
84904898065
-
AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer
-
Cross DA, Ashton SE, Ghiorghiu S, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov 2014; 4: 1046-61.
-
(2014)
Cancer Discov
, vol.4
, pp. 1046-1061
-
-
Cross, D.A.1
Ashton, S.E.2
Ghiorghiu, S.3
-
57
-
-
84928739294
-
AZD9291 in EGFR inhibitorresistant non-small-cell lung cancer
-
Janne PA, Yang JC, Kim DW, et al. AZD9291 in EGFR inhibitorresistant non-small-cell lung cancer. N Engl J Med 2015; 372: 1689-99.
-
(2015)
N Engl J Med
, vol.372
, pp. 1689-1699
-
-
Janne, P.A.1
Yang, J.C.2
Kim, D.W.3
-
58
-
-
84906911022
-
Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFRmutant lung cancer with and without T790M mutations
-
Janjigian YY, Smit EF, Groen HJ, et al. Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFRmutant lung cancer with and without T790M mutations. Cancer Discov 2014; 4: 1036-45.
-
(2014)
Cancer Discov
, vol.4
, pp. 1036-1045
-
-
Janjigian, Y.Y.1
Smit, E.F.2
Groen, H.J.3
-
59
-
-
79954586068
-
Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib
-
Janjigian YY, Azzoli CG, Krug LM, et al. Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib. Clin Cancer Res 2011; 17: 2521-7.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2521-2527
-
-
Janjigian, Y.Y.1
Azzoli, C.G.2
Krug, L.M.3
-
60
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin’s lymphoma
-
Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin’s lymphoma. Science 1994; 263: 1281-4.
-
(1994)
Science
, vol.263
, pp. 1281-1284
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
-
61
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007; 448: 561-6.
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
62
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010; 363: 1693-703.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
63
-
-
57349113565
-
Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts
-
Takeuchi K, Choi YL, Soda M, et al. Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res 2008; 14: 6618-24.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6618-6624
-
-
Takeuchi, K.1
Choi, Y.L.2
Soda, M.3
-
64
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008; 14: 4275-83.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
65
-
-
65249095599
-
The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
-
Wong DW, Leung EL, So KK, et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009; 115: 1723-33.
-
(2009)
Cancer
, vol.115
, pp. 1723-1733
-
-
Wong, D.W.1
Leung, E.L.2
So, K.K.3
-
66
-
-
77953291664
-
The biology and treatment of EML4-ALK non-small cell lung cancer
-
Sasaki T, Rodig SJ, Chirieac LR, Janne PA. The biology and treatment of EML4-ALK non-small cell lung cancer. Eur J Cancer 2010; 46: 1773-80.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1773-1780
-
-
Sasaki, T.1
Rodig, S.J.2
Chirieac, L.R.3
Janne, P.A.4
-
67
-
-
79954606778
-
Targeting anaplastic lymphoma kinase in lung cancer
-
Shaw AT, Solomon B. Targeting anaplastic lymphoma kinase in lung cancer. Clin Cancer Res 2011; 17: 2081-6.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2081-2086
-
-
Shaw, A.T.1
Solomon, B.2
-
68
-
-
77954399760
-
Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
-
Zhang X, Zhang S, Yang X, et al. Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Mol Cancer 2010; 9: 188.
-
(2010)
Mol Cancer
, vol.9
, pp. 188
-
-
Zhang, X.1
Zhang, S.2
Yang, X.3
-
69
-
-
37549059613
-
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lym phoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma
-
Christensen JG, Zou HY, Arango ME, et al. Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lym phoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma. Mol Cancer Ther 2007; 6: 3314-22.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 3314-3322
-
-
Christensen, J.G.1
Zou, H.Y.2
Arango, M.E.3
-
70
-
-
84918804764
-
First-line crizotinib versus chemotherapy in ALK-positive lung cancer
-
Solomon BJ, Mok T, Kim DW, et al. First-line crizotinib versus chemotherapy in ALK-positive lung cancer. N Engl J Med 2014; 371: 2167-77.
-
(2014)
N Engl J Med
, vol.371
, pp. 2167-2177
-
-
Solomon, B.J.1
Mok, T.2
Kim, D.W.3
-
71
-
-
84896957081
-
Ceritinib in ALK-rearranged non-small-cell lung cancer
-
Shaw AT, Kim DW, Mehra R, et al. Ceritinib in ALK-rearranged non-small-cell lung cancer. N Engl J Med 2014; 370: 1189-97.
-
(2014)
N Engl J Med
, vol.370
, pp. 1189-1197
-
-
Shaw, A.T.1
Kim, D.W.2
Mehra, R.3
-
72
-
-
0023477402
-
Expression and rearrangement of the ROS1 gene in human glioblastoma cells
-
Birchmeier C, Sharma S, Wigler M. Expression and rearrangement of the ROS1 gene in human glioblastoma cells. Proc Natl Acad Sci USA 1987; 84: 9270-4.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 9270-9274
-
-
Birchmeier, C.1
Sharma, S.2
Wigler, M.3
-
74
-
-
33747887175
-
ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice
-
Charest A, Wilker EW, McLaughlin ME, et al. ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice. Cancer Res 2006; 66: 7473-81.
-
(2006)
Cancer Res
, vol.66
, pp. 7473-7481
-
-
Charest, A.1
Wilker, E.W.2
McLaughlin, M.E.3
-
75
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
Rikova K, Guo A, Zeng Q, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007; 131: 1190-203.
-
(2007)
Cell
, vol.131
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
-
76
-
-
84857985225
-
RET, ROS1 and ALK fusions in lung cancer
-
Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med 2012; 18: 378-81.
-
(2012)
Nat Med
, vol.18
, pp. 378-381
-
-
Takeuchi, K.1
Soda, M.2
Togashi, Y.3
-
77
-
-
84865441368
-
Identifying and targeting ROS1 gene fusions in non-small cell lung cancer
-
Davies KD, Le AT, Theodoro MF, et al. Identifying and targeting ROS1 gene fusions in non-small cell lung cancer. Clin Cancer Res 2012; 18: 4570-9.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4570-4579
-
-
Davies, K.D.1
Le, A.T.2
Theodoro, M.F.3
-
78
-
-
84863338079
-
ROS1 rearrangements define a unique molecular class of lung cancers
-
Bergethon K, Shaw AT, Ou SH, et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012; 30: 863-70.
-
(2012)
J Clin Oncol
, vol.30
, pp. 863-870
-
-
Bergethon, K.1
Shaw, A.T.2
Ou, S.H.3
-
79
-
-
84911372597
-
Crizotinib in ROS1-rearranged non-small-cell lung cancer
-
Shaw AT, Ou SH, Bang YJ, et al. Crizotinib in ROS1-rearranged non-small-cell lung cancer. N Engl J Med 2014; 371: 1963-71.
-
(2014)
N Engl J Med
, vol.371
, pp. 1963-1971
-
-
Shaw, A.T.1
Ou, S.H.2
Bang, Y.J.3
-
80
-
-
84927139647
-
Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: Results from the EUROS1 cohort
-
Mazieres J, Zalcman G, Crino L, et al. Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: results from the EUROS1 cohort. J Clin Oncol 2015; 33: 992-9.
-
(2015)
J Clin Oncol
, vol.33
, pp. 992-999
-
-
Mazieres, J.1
Zalcman, G.2
Crino, L.3
-
81
-
-
9244255770
-
Development of thyroid papillary carcinomas secondary to tissue-specific expression of the RET/PTC1 oncogene in transgenic mice
-
Santoro M, Chiappetta G, Cerrato A, et al. Development of thyroid papillary carcinomas secondary to tissue-specific expression of the RET/PTC1 oncogene in transgenic mice. Oncogene 1996; 12: 1821-6.
-
(1996)
Oncogene
, vol.12
, pp. 1821-1826
-
-
Santoro, M.1
Chiappetta, G.2
Cerrato, A.3
-
82
-
-
84870748688
-
RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer
-
Wang R, Hu H, Pan Y, et al. RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer. J Clin Oncol 2012; 30: 4352-9.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4352-4359
-
-
Wang, R.1
Hu, H.2
Pan, Y.3
-
83
-
-
0021362206
-
Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
-
Santos E, Martin-Zanca D, Reddy EP, Pierotti MA, Della Porta G, Barbacid M. Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science 1984; 223: 661-4.
-
(1984)
Science
, vol.223
, pp. 661-664
-
-
Santos, E.1
Martin-Zanca, D.2
Reddy, E.P.3
Pierotti, M.A.4
Della Porta, G.5
Barbacid, M.6
-
84
-
-
84900829967
-
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
-
Kris MG, Johnson BE, Berry LD, et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA 2014; 311: 1998-2006.
-
(2014)
JAMA
, vol.311
, pp. 1998-2006
-
-
Kris, M.G.1
Johnson, B.E.2
Berry, L.D.3
-
85
-
-
53249145767
-
Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma
-
Riely GJ, Kris MG, Rosenbaum D, et al. Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. Clin Cancer Res 2008; 14: 5731-4.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5731-5734
-
-
Riely, G.J.1
Kris, M.G.2
Rosenbaum, D.3
-
86
-
-
78049515002
-
Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases
-
Sun Y, Ren Y, Fang Z, et al. Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol 2010; 28: 4616-20.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4616-4620
-
-
Sun, Y.1
Ren, Y.2
Fang, Z.3
-
87
-
-
82355191818
-
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
-
Sequist LV, Heist RS, Shaw AT, et al. Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice. Ann Oncol 2011; 22: 2616-24.
-
(2011)
Ann Oncol
, vol.22
, pp. 2616-2624
-
-
Sequist, L.V.1
Heist, R.S.2
Shaw, A.T.3
-
88
-
-
84881374148
-
Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy
-
Shepherd FA, Domerg C, Hainaut P, et al. Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy. J Clin Oncol 2013; 31: 2173-81.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2173-2181
-
-
Shepherd, F.A.1
Domerg, C.2
Hainaut, P.3
-
89
-
-
19944430434
-
The role of RAS oncogene in survival of patients with lung cancer: A systematic review of the literature with meta-analysis
-
Mascaux C, Iannino N, Martin B, et al. The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis. Br J Cancer 2005; 92: 131-9.
-
(2005)
Br J Cancer
, vol.92
, pp. 131-139
-
-
Mascaux, C.1
Iannino, N.2
Martin, B.3
-
90
-
-
77953361374
-
Clinical outcome of patients with non-small cell lung cancer receiving front-line chemotherapy according to EGFR and K-RAS mutation status
-
Kalikaki A, Koutsopoulos A, Hatzidaki D, et al. Clinical outcome of patients with non-small cell lung cancer receiving front-line chemotherapy according to EGFR and K-RAS mutation status. Lung Cancer 2010; 69: 110-5.
-
(2010)
Lung Cancer
, vol.69
, pp. 110-115
-
-
Kalikaki, A.1
Koutsopoulos, A.2
Hatzidaki, D.3
-
91
-
-
79955483992
-
The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients
-
Camps C, Jantus-Lewintre E, Cabrera A, et al. The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients. Lung Cancer 2011; 72: 365-9.
-
(2011)
Lung Cancer
, vol.72
, pp. 365-369
-
-
Camps, C.1
Jantus-Lewintre, E.2
Cabrera, A.3
-
92
-
-
77953541527
-
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study
-
Cappuzzo F, Ciuleanu T, Stelmakh L, et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010; 11: 521-9.
-
(2010)
Lancet Oncol
, vol.11
, pp. 521-529
-
-
Cappuzzo, F.1
Ciuleanu, T.2
Stelmakh, L.3
-
93
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and metaanalysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H, Dahabreh IJ, Kanaloupiti D, et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and metaanalysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008; 9: 962-72.
-
(2008)
Lancet Oncol
, vol.9
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
-
94
-
-
84864925900
-
Proteins involved in DNA damage response pathways and survival of stage I non-small-cell lung cancer patients
-
Choi CM, Yang SC, Jo HJ, et al. Proteins involved in DNA damage response pathways and survival of stage I non-small-cell lung cancer patients. Ann Oncol 2012; 23: 2088-93.
-
(2012)
Ann Oncol
, vol.23
, pp. 2088-2093
-
-
Choi, C.M.1
Yang, S.C.2
Jo, H.J.3
-
95
-
-
84875181563
-
ERCC1 isoform expression and DNA repair in non-small-cell lung cancer
-
Friboulet L, Olaussen KA, Pignon JP, et al. ERCC1 isoform expression and DNA repair in non-small-cell lung cancer. N Engl J Med 2013; 368: 1101-10.
-
(2013)
N Engl J Med
, vol.368
, pp. 1101-1110
-
-
Friboulet, L.1
Olaussen, K.A.2
Pignon, J.P.3
-
96
-
-
0035988959
-
Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer
-
Lord RV, Brabender J, Gandara D, et al. Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer. Clin Cancer Res 2002; 8: 2286-91.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2286-2291
-
-
Lord, R.V.1
Brabender, J.2
Gandara, D.3
-
97
-
-
33748435058
-
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
-
Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006; 355: 983-91.
-
(2006)
N Engl J Med
, vol.355
, pp. 983-991
-
-
Olaussen, K.A.1
Dunant, A.2
Fouret, P.3
-
98
-
-
2342616723
-
Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy
-
Ryu JS, Hong YC, Han HS, et al. Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy. Lung Cancer 2004; 44: 311-6.
-
(2004)
Lung Cancer
, vol.44
, pp. 311-316
-
-
Ryu, J.S.1
Hong, Y.C.2
Han, H.S.3
-
99
-
-
84883115851
-
Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer
-
Bepler G, Williams C, Schell MJ, et al. Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer. J Clin Oncol 2013; 31: 2404-12.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2404-2412
-
-
Bepler, G.1
Williams, C.2
Schell, M.J.3
-
100
-
-
34447573875
-
Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small-cell lung cancer
-
Cobo M, Isla D, Massuti B, et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 2007; 25: 2747-54.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2747-2754
-
-
Cobo, M.1
Isla, D.2
Massuti, B.3
-
101
-
-
79953713046
-
ERCC1 expression analysis to guide therapy in non-small cell lung cancer
-
Allingham-Hawkins D, Lea A, Levine S. ERCC1 expression analysis to guide therapy in non-small cell lung cancer. PLoS Curr 2010; 2: RRN1202.
-
(2010)
Plos Curr
, vol.2
-
-
Allingham-Hawkins, D.1
Lea, A.2
Levine, S.3
-
102
-
-
34447534435
-
ERCC1-tailored chemotherapy in lung cancer: The first prospective randomized trial
-
Soria JC. ERCC1-tailored chemotherapy in lung cancer: the first prospective randomized trial. J Clin Oncol 2007; 25: 2648-9.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2648-2649
-
-
Soria, J.C.1
-
103
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
Bean J, Brennan C, Shih JY, et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci USA 2007; 104: 20932-7.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.Y.3
-
104
-
-
78651079558
-
A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer
-
Su Z, Dias-Santagata D, Duke M, et al. A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer. J Mol Diagn 2011; 13: 74-84.
-
(2011)
J Mol Diagn
, vol.13
, pp. 74-84
-
-
Su, Z.1
Dias-Santagata, D.2
Duke, M.3
-
105
-
-
77954566882
-
Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine
-
Dias-Santagata D, Akhavanfard S, David SS, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. EMBO Mol Med 2010; 2: 146-58.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 146-158
-
-
Dias-Santagata, D.1
Akhavanfard, S.2
David, S.S.3
-
106
-
-
80555139776
-
Identification of driver mutations in tumor specimens from 1, 000 patients with lung adenocarcinoma: The NCI’s Lung Cancer Mutation Consortium (LCMC)
-
Kris MG, Johnson BE, Kwiatkowski DJ, et al. Identification of driver mutations in tumor specimens from 1, 000 patients with lung adenocarcinoma: The NCI’s Lung Cancer Mutation Consortium (LCMC). J Clin Oncol 2011; 29.
-
(2011)
J Clin Oncol
, pp. 29
-
-
Kris, M.G.1
Johnson, B.E.2
Kwiatkowski, D.J.3
-
107
-
-
70849116358
-
Profiling critical cancer gene mutations in clinical tumor samples
-
MacConaill LE, Campbell CD, Kehoe SM, et al. Profiling critical cancer gene mutations in clinical tumor samples. PLoS One 2009; 4: e7887.
-
(2009)
Plos One
, vol.4
-
-
Macconaill, L.E.1
Campbell, C.D.2
Kehoe, S.M.3
-
108
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 2015; 373: 123-35.
-
(2015)
N Engl J Med
, vol.373
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
-
109
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
Garon EB, Rizvi NA, Hui R, et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med 2015; 372: 2018-28.
-
(2015)
N Engl J Med
, vol.372
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
-
110
-
-
84922669340
-
Immune checkpoint inhibitors in advanced nonsmall cell lung cancer
-
Helissey C, Champiat S, Soria JC. Immune checkpoint inhibitors in advanced nonsmall cell lung cancer. Curr Opin Oncol 2015; 27: 108-17.
-
(2015)
Curr Opin Oncol
, vol.27
, pp. 108-117
-
-
Helissey, C.1
Champiat, S.2
Soria, J.C.3
-
111
-
-
84872017586
-
Circulating tumor cells: Liquid biopsy of cancer
-
Alix-Panabieres C, Pantel K. Circulating tumor cells: liquid biopsy of cancer. Clin Chem 2013; 59: 110-8.
-
(2013)
Clin Chem
, vol.59
, pp. 110-118
-
-
Alix-Panabieres, C.1
Pantel, K.2
-
113
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson SJ, Tsui DW, Murtaza M, et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med 2013; 368: 1199-209.
-
(2013)
N Engl J Med
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
Tsui, D.W.2
Murtaza, M.3
-
114
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
-
Murtaza M, Dawson SJ, Tsui DW, et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013; 497: 108-12.
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
Dawson, S.J.2
Tsui, D.W.3
-
115
-
-
6044259206
-
Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases
-
Allard WJ, Matera J, Miller MC, et al. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases. Clin Cancer Res 2004; 10: 6897-904.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6897-6904
-
-
Allard, W.J.1
Matera, J.2
Miller, M.C.3
-
116
-
-
79955045007
-
Evaluation and prognostic significance of circulating tumor cells in patients with non-smallcell lung cancer
-
Krebs MG, Sloane R, Priest L, et al. Evaluation and prognostic significance of circulating tumor cells in patients with non-smallcell lung cancer. J Clin Oncol 2011; 29: 1556-63.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1556-1563
-
-
Krebs, M.G.1
Sloane, R.2
Priest, L.3
-
117
-
-
84868106386
-
Circulating tumor cells in small-cell lung cancer: A predictive and prognostic factor
-
Hiltermann TJ, Pore MM, van den Berg A, et al. Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor. Ann Oncol 2012; 23: 2937-42.
-
(2012)
Ann Oncol
, vol.23
, pp. 2937-2942
-
-
Hiltermann, T.J.1
Pore, M.M.2
Van Den Berg, A.3
-
118
-
-
53349177819
-
Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
-
Chen X, Ba Y, Ma L, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008; 18: 997-1006.
-
(2008)
Cell Res
, vol.18
, pp. 997-1006
-
-
Chen, X.1
Ba, Y.2
Ma, L.3
-
119
-
-
84889022338
-
Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer
-
Weber DG, Johnen G, Casjens S, et al. Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer. BMC Res Notes 2013; 6: 518.
-
(2013)
BMC Res Notes
, vol.6
, pp. 518
-
-
Weber, D.G.1
Johnen, G.2
Casjens, S.3
-
120
-
-
0017360626
-
Free DNA in the serum of cancer patients and the effect of therapy
-
Leon SA, Shapiro B, Sklaroff DM, Yaros MJ. Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res 1977; 37: 646-50.
-
(1977)
Cancer Res
, vol.37
, pp. 646-650
-
-
Leon, S.A.1
Shapiro, B.2
Sklaroff, D.M.3
Yaros, M.J.4
-
121
-
-
84859515309
-
The multifaceted exosome: Biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities
-
Pant S, Hilton H, Burczynski ME. The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities. Biochem Pharmacol 2012; 83: 1484-94.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 1484-1494
-
-
Pant, S.1
Hilton, H.2
Burczynski, M.E.3
-
124
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007; 9: 654-9.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
125
-
-
84907059485
-
Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors
-
Wilson CM, Naves T, Vincent F, et al. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors. J Cell Sci 2014; 127: 3983-97.
-
(2014)
J Cell Sci
, vol.127
, pp. 3983-3997
-
-
Wilson, C.M.1
Naves, T.2
Vincent, F.3
-
126
-
-
84904393091
-
Different exosome cargo from plasma/bronchoalveolar lavage in non-small-cell lung cancer
-
Rodriguez M, Silva J, Lopez-Alfonso A, et al. Different exosome cargo from plasma/bronchoalveolar lavage in non-small-cell lung cancer. Genes Chromosomes Cancer 2014; 53: 713-24.
-
(2014)
Genes Chromosomes Cancer
, vol.53
, pp. 713-724
-
-
Rodriguez, M.1
Silva, J.2
Lopez-Alfonso, A.3
-
127
-
-
84875057635
-
Exosomes as intercellular signaling organelles involved in health and disease: Basic science and clinical applications
-
Corrado C, Raimondo S, Chiesi A, Ciccia F, De Leo G, Alessandro R. Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications. Int J Mol Sci 2013; 14: 5338-66.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 5338-5366
-
-
Corrado, C.1
Raimondo, S.2
Chiesi, A.3
Ciccia, F.4
De Leo, G.5
Alessandro, R.6
-
128
-
-
84887138426
-
Real-time liquid biopsy in cancer patients: Fact or fiction?
-
Pantel K, Alix-Panabieres C. Real-time liquid biopsy in cancer patients: fact or fiction? Cancer Res 2013; 73: 6384-8.
-
(2013)
Cancer Res
, vol.73
, pp. 6384-6388
-
-
Pantel, K.1
Alix-Panabieres, C.2
-
129
-
-
84901842265
-
Double-stranded DNA in exosomes: A novel biomarker in cancer detection
-
Thakur BK, Zhang H, Becker A, et al. Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell Res 2014; 24: 766-9.
-
(2014)
Cell Res
, vol.24
, pp. 766-769
-
-
Thakur, B.K.1
Zhang, H.2
Becker, A.3
-
130
-
-
84875427494
-
Microenvironment: Making connections. Nature Reviews
-
Seton-Rogers S. Microenvironment: making connections. Nature Reviews. Cancer 2013; 13: 222-3.
-
(2013)
Cancer
, vol.13
, pp. 222-223
-
-
Seton-Rogers, S.1
-
131
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He L, & Hannon, G. J. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004; 5: 522-31.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
132
-
-
48749122914
-
Circulating microRNAs as stable blood-based markers for cancer detection
-
Mitchell PS, Parkin RK, Kroh EM, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 2008; 105: 10513-8.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10513-10518
-
-
Mitchell, P.S.1
Parkin, R.K.2
Kroh, E.M.3
-
133
-
-
79961025970
-
MicroRNAs in body fluids—the mix of hormones and biomarkers
-
Cortez MA, Bueso-Ramos C, Ferdin J, Lopez-Berestein G, Sood AK, Calin GA. MicroRNAs in body fluids—the mix of hormones and biomarkers. Nat Rev Clin Oncol 2011; 8: 467-77.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 467-477
-
-
Cortez, M.A.1
Bueso-Ramos, C.2
Ferdin, J.3
Lopez-Berestein, G.4
Sood, A.K.5
Calin, G.A.6
-
135
-
-
69949117622
-
Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
-
Gibbings DJ, Ciaudo C, Erhardt M, & Voinnet O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol 2009; 11: 1143-9.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1143-1149
-
-
Gibbings, D.J.1
Ciaudo, C.2
Erhardt, M.3
Voinnet, O.4
-
136
-
-
84872704002
-
Exosome can prevent RNase from degrading microRNA in feces
-
Koga Y, Yasunaga M, Moriya Y, et al. Exosome can prevent RNase from degrading microRNA in feces. J Gastrointestinal Oncol 2011; 2: 215-22.
-
(2011)
J Gastrointestinal Oncol
, vol.2
, pp. 215-222
-
-
Koga, Y.1
Yasunaga, M.2
Moriya, Y.3
-
137
-
-
75649119273
-
Mesenchymal stem cell secretes microparticles enriched in premicroRNAs
-
Chen TS, Lai RC, Lee MM, Choo AB, Lee CN, Lim SK. Mesenchymal stem cell secretes microparticles enriched in premicroRNAs. Nucleic Acids Res 2010; 38: 215-224.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 215-224
-
-
Chen, T.S.1
Lai, R.C.2
Lee, M.M.3
Choo, A.B.4
Lee, C.N.5
Lim, S.K.6
-
138
-
-
77955500933
-
MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila
-
Flynt AS, Greimann JC, Chung WJ, Lima CD, Lai EC. MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila. Mol Cell 2010; 38: 900-7.
-
(2010)
Mol Cell
, vol.38
, pp. 900-907
-
-
Flynt, A.S.1
Greimann, J.C.2
Chung, W.J.3
Lima, C.D.4
Lai, E.C.5
-
139
-
-
84861419046
-
Exosomal RNA as biomarkers and the therapeu-tic potential of exosome vectors
-
Lasser C. Exosomal RNA as biomarkers and the therapeu-tic potential of exosome vectors. Expert Opin Bioll Ther 2012; 12: S189-97.
-
(2012)
Expert Opin Bioll Ther
, vol.12
, pp. S189-S197
-
-
Lasser, C.1
-
140
-
-
62549125455
-
Exosomal microRNA: A diagnostic marker for lung cancer
-
Rabinowits G, Gercel-Taylor C, Day JM, Taylor DD, Kloecker GH. Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer 2009; 10: 42-46.
-
(2009)
Clin Lung Cancer
, vol.10
, pp. 42-46
-
-
Rabinowits, G.1
Gercel-Taylor, C.2
Day, J.M.3
Taylor, D.D.4
Kloecker, G.H.5
-
141
-
-
84858037808
-
Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
-
Tauro BJ, Greening DW, Mathias RA, et al. Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods 2012; 56: 293-304.
-
(2012)
Methods
, vol.56
, pp. 293-304
-
-
Tauro, B.J.1
Greening, D.W.2
Mathias, R.A.3
-
142
-
-
84874755851
-
Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma
-
Tanaka Y, Kamohara H, Kinoshita K, et al. Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma. Cancer 2013; 119: 1159-67.
-
(2013)
Cancer
, vol.119
, pp. 1159-1167
-
-
Tanaka, Y.1
Kamohara, H.2
Kinoshita, K.3
-
143
-
-
84884273390
-
Clinical implications of microRNAs in human glioblastoma
-
Mizoguchi M, Guan Y, Yoshimoto K, et al. Clinical implications of microRNAs in human glioblastoma. Frontiers Oncol 2013; 3: 19.
-
(2013)
Frontiers Oncol
, vol.3
, pp. 19
-
-
Mizoguchi, M.1
Guan, Y.2
Yoshimoto, K.3
-
144
-
-
84867575631
-
Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers
-
Alvarez ML, Khosroheidari M, Kanchi RR, DiStefano JK. Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers. Kidney Int 2012; 82: 1024-32.
-
(2012)
Kidney Int
, vol.82
, pp. 1024-1032
-
-
Alvarez, M.L.1
Khosroheidari, M.2
Kanchi, R.R.3
Distefano, J.K.4
-
145
-
-
84879419464
-
Leukemia cell to endothelial cell communication via exosomal miRNAs
-
Umezu T, Ohyashiki K, Kuroda M, Ohyashiki. JH. Leukemia cell to endothelial cell communication via exosomal miRNAs. Oncogene 2013; 32: 2747-55.
-
(2013)
Oncogene
, vol.32
, pp. 2747-2755
-
-
Umezu, T.1
Ohyashiki, K.2
Kuroda, M.3
-
146
-
-
84860638692
-
Cell-secreted vesicles in equine ovarian follicular fluid contain miRNAs and proteins: A possible new form of cell communication within the ovarian follicle
-
da Silveira JC, Veeramachaneni DN, Winger QA, Carnevale EM, Bouma GJ. Cell-secreted vesicles in equine ovarian follicular fluid contain miRNAs and proteins: a possible new form of cell communication within the ovarian follicle. Biol Reprod 2012; 86: 71.
-
(2012)
Biol Reprod
, vol.86
, pp. 71
-
-
Da Silveira, J.C.1
Veeramachaneni, D.N.2
Winger, Q.A.3
Carnevale, E.M.4
Bouma, G.J.5
-
147
-
-
84867417250
-
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells. Biochimica et Biophysica Acta, 1819, 1154-1163. Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
-
Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A. Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells. Biochimica et Biophysica Acta, 1819, 1154-1163. Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells. Biochim Biophys Acta 2012; 1819: 1154-63.
-
(2012)
Biochim Biophys Acta
, vol.1819
, pp. 1154-1163
-
-
Hessvik, N.P.1
Phuyal, S.2
Brech, A.3
Sandvig, K.4
Llorente, A.5
-
148
-
-
84876186916
-
Exosomal miRNAs as biomarkers for prostate cancer
-
Hessvik NP, Sandvig K, Llorente. A. Exosomal miRNAs as biomarkers for prostate cancer. Front Genet 2013; 4: 36.
-
(2013)
Front Genet
, vol.4
, pp. 36
-
-
Hessvik, N.P.1
Sandvig, K.2
-
149
-
-
66949145155
-
Exosomes: Proteomic insights and diagnostic potential
-
Simpson RJ, Lim JW, Moritz RL, Mathivanan. S. Exosomes: proteomic insights and diagnostic potential. Exp Rev Proteomics 2009; 6: 267-83.
-
(2009)
Exp Rev Proteomics
, vol.6
, pp. 267-283
-
-
Simpson, R.J.1
Lim, J.W.2
Moritz, R.L.3
-
150
-
-
84886367490
-
Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia
-
Ferrajoli A, Shanafelt TD, Ivan C, et al. Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. Blood 2013; 122: 1891-9.
-
(2013)
Blood
, vol.122
, pp. 1891-1899
-
-
Ferrajoli, A.1
Shanafelt, T.D.2
Ivan, C.3
-
151
-
-
84935921168
-
miR-141 and miR-375 induction and release are different from PSA mRNA and PCA3 upon androgen stimulation of LNCaP cells
-
Tiryakioglu D, Bilgin E, Holdenrieder S, Dalay N, Gezer. U. miR-141 and miR-375 induction and release are different from PSA mRNA and PCA3 upon androgen stimulation of LNCaP cells. Biomed Rep 2013; 1: 802-6.
-
(2013)
Biomed Rep
, vol.1
, pp. 802-806
-
-
Tiryakioglu, D.1
Bilgin, E.2
Holdenrieder, S.3
Dalay, N.4
-
152
-
-
45449093192
-
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
-
D.D. T, Gercel-Taylor. C
-
D.D. T, Gercel-Taylor. C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol 2008; 110: 13-21.
-
(2008)
Gynecol Oncol
, vol.110
, pp. 13-21
-
-
-
153
-
-
62549116582
-
Circulating microRNA signatures of tumor-derived exosomes for early diagnosis of non-small-cell lung cancer
-
Rosell R, Wei J, Taron M. Circulating microRNA signatures of tumor-derived exosomes for early diagnosis of non-small-cell lung cancer. Clin Lung Cancer 2009; 10: 8-9.
-
(2009)
Clin Lung Cancer
, vol.10
, pp. 8-9
-
-
Rosell, R.1
Wei, J.2
Taron, M.3
-
154
-
-
84875232250
-
Serum microRNA expression profile: MiR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma
-
Takeshita N, Hoshino I, Mori M, Akutsu Y, Hanari N, al. YYe. Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma. Br J Cancer 2013; 108: 644-52.
-
(2013)
Br J Cancer
, vol.108
, pp. 644-652
-
-
Takeshita, N.1
Hoshino, I.2
Mori, M.3
Akutsu, Y.4
Hanari, N.5
-
155
-
-
70350449455
-
ExoCarta: A compendium of exosomal proteins and RNA
-
Mathivanan S, Simpson RJ. ExoCarta: A compendium of exosomal proteins and RNA. Proteomics 2009; 9: 4997-5000.
-
(2009)
Proteomics
, vol.9
, pp. 4997-5000
-
-
Mathivanan, S.1
Simpson, R.J.2
-
156
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer 2004; 4: 361-70.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
157
-
-
78650678063
-
Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
-
Vaegter CB, Jansen P, Fjorback AW, et al. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci 2011; 14: 54-61.
-
(2011)
Nat Neurosci
, vol.14
, pp. 54-61
-
-
Vaegter, C.B.1
Jansen, P.2
Fjorback, A.W.3
-
158
-
-
80053157959
-
Finetuning roles of endogenous brain-derived neurotrophic factor, TrkB and sortilin in colorectal cancer cell survival
-
Akil H, Perraud A, Melin C, Jauberteau MO, Mathonnet M. Finetuning roles of endogenous brain-derived neurotrophic factor, TrkB and sortilin in colorectal cancer cell survival. PLoS One 2011; 6: p. e25097.
-
(2011)
Plos One
, vol.6
-
-
Akil, H.1
Perraud, A.2
Melin, C.3
Jauberteau, M.O.4
Mathonnet, M.5
-
159
-
-
84907058201
-
The implications of sortilin/ vps10p domain receptors in neurological and human diseases
-
Wilson CM, Naves T, Saada S, et al. The implications of sortilin/ vps10p domain receptors in neurological and human diseases. CNS Neurol Disord Drug Targets 2014; 13: 1354-65.
-
(2014)
CNS Neurol Disord Drug Targets
, vol.13
, pp. 1354-1365
-
-
Wilson, C.M.1
Naves, T.2
Saada, S.3
-
160
-
-
0035874064
-
Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines
-
Dal Farra C, Sarret P, Navarro V, et al. Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines. Int J Cancer 2001; 92: 503-9.
-
(2001)
Int J Cancer
, vol.92
, pp. 503-509
-
-
Dal Farra, C.1
Sarret, P.2
Navarro, V.3
-
161
-
-
47349111926
-
Neurotrophins and their receptors stimulate melanoma cell proliferation and migration
-
Truzzi F, Marconi A, Lotti R, et al. Neurotrophins and their receptors stimulate melanoma cell proliferation and migration. J Invest Dermatol 2008; 128: 2031-40.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2031-2040
-
-
Truzzi, F.1
Marconi, A.2
Lotti, R.3
-
162
-
-
49449103361
-
Expression of neurotensin and its receptors in pituitary adenomas
-
Giorgi RR, Chile T, Bello AR, et al. Expression of neurotensin and its receptors in pituitary adenomas. J Neuroendocrinol 2008; 20: 1052-7.
-
(2008)
J Neuroendocrinol
, vol.20
, pp. 1052-1057
-
-
Giorgi, R.R.1
Chile, T.2
Bello, A.R.3
-
163
-
-
84880671154
-
ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro
-
Xiong J, Zhou L, Mea Y. ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro. Neurooncology 2013; 15: 990-1007.
-
(2013)
Neurooncology
, vol.15
, pp. 990-1007
-
-
Xiong, J.1
Zhou, L.2
Mea, Y.3
-
164
-
-
84878653585
-
Contribution of proteomics to understanding the role of tumor-derived exosomes in cancer progression: State of the art and new perspectives
-
Fontana S, Saieva L, Taverna S, Alessandro R. Contribution of proteomics to understanding the role of tumor-derived exosomes in cancer progression: state of the art and new perspectives. Proteomics 2013; 13: 1581-94.
-
(2013)
Proteomics
, vol.13
, pp. 1581-1594
-
-
Fontana, S.1
Saieva, L.2
Taverna, S.3
Alessandro, R.4
-
165
-
-
79960728743
-
Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC
-
Li Y, Zhang Y, Qiu F, Qiu Z. Proteomic identification of exosomal LRG1: a potential urinary biomarker for detecting NSCLC. Electrophoresis 2011; 32: 1976-83.
-
(2011)
Electrophoresis
, vol.32
, pp. 1976-1983
-
-
Li, Y.1
Zhang, Y.2
Qiu, F.3
Qiu, Z.4
-
166
-
-
84892702249
-
Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis
-
Yamashita T, Kamada H, Kanasaki S, et al. Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis. Pharmazie 2013; 68: 969-73.
-
(2013)
Pharmazie
, vol.68
, pp. 969-973
-
-
Yamashita, T.1
Kamada, H.2
Kanasaki, S.3
-
167
-
-
84877947179
-
Epidermal growth factor receptor-containing exosomes induce tumor-specific regulatory T cells
-
Huang SH, Li Y, Zhang J, Rong J, Ye S. Epidermal growth factor receptor-containing exosomes induce tumor-specific regulatory T cells. Cancer Invest 2013; 31: 330-5.
-
(2013)
Cancer Invest
, vol.31
, pp. 330-335
-
-
Huang, S.H.1
Li, Y.2
Zhang, J.3
Rong, J.4
Ye, S.5
-
168
-
-
84906818368
-
Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes
-
Ueda K, Ishikawa N, Tatsuguchi A, Saichi N, Fujii R, Nakagawa H. Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Sci Rep 2014; 4: 6232.
-
(2014)
Sci Rep
, vol.4
, pp. 6232
-
-
Ueda, K.1
Ishikawa, N.2
Tatsuguchi, A.3
Saichi, N.4
Fujii, R.5
Nakagawa, H.6
-
169
-
-
85016462671
-
Exosomal proteins as potential diagnostic markers in advanced non-small cell lung carcinoma
-
Jakobsen KR, Paulsen BS, Bæk R, Varming K, Sorensen BS, Jørgensen. MM. Exosomal proteins as potential diagnostic markers in advanced non-small cell lung carcinoma. J Extracell Vesicles 2015; 4: 26659.
-
(2015)
J Extracell Vesicles
, vol.4
, pp. 26659
-
-
Jakobsen, K.R.1
Paulsen, B.S.2
Bæk, R.3
Varming, K.4
Sorensen, B.S.5
-
170
-
-
84874967621
-
Exosomal tumorsuppressive microRNAs as novel cancer therapy: “exocure” is another choice for cancer treatment
-
Kosaka N, Takeshita F, Yoshioka Y, et al. Exosomal tumorsuppressive microRNAs as novel cancer therapy: “exocure” is another choice for cancer treatment. Adv Drug Deliv Rev 2013; 65: 376-82.
-
(2013)
Adv Drug Deliv Rev
, vol.65
, pp. 376-382
-
-
Kosaka, N.1
Takeshita, F.2
Yoshioka, Y.3
-
171
-
-
77952920881
-
Secretory mechanisms and intercellular transfer of microRNAs in living cells
-
Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, Ochiya T. Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem 2010; 285: 17442-52.
-
(2010)
J Biol Chem
, vol.285
, pp. 17442-17452
-
-
Kosaka, N.1
Iguchi, H.2
Yoshioka, Y.3
Takeshita, F.4
Matsuki, Y.5
Ochiya, T.6
-
172
-
-
84876248584
-
Neutral sphingomyelinase 2 (NSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis
-
Kosaka N, Iguchi H, Hagiwara K, Yoshioka Y, Takeshita F, Ochiya T. Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis. J Biol Chem 2013; 288: 10849-59.
-
(2013)
J Biol Chem
, vol.288
, pp. 10849-10859
-
-
Kosaka, N.1
Iguchi, H.2
Hagiwara, K.3
Yoshioka, Y.4
Takeshita, F.5
Ochiya, T.6
-
173
-
-
84908897430
-
B-Elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome
-
Li J, JunYu, Liu A, Wang Y. b-Elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome. Lung Cancer 2014; 86: 144-50.
-
(2014)
Lung Cancer
, vol.86
, pp. 144-150
-
-
Li, J.1
-
175
-
-
84905705777
-
Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment
-
Choi DY, You S, Jung JH, et al. Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment. Proteomics 2014; 14: 1845-56.
-
(2014)
Proteomics
, vol.14
, pp. 1845-1856
-
-
Choi, D.Y.1
You, S.2
Jung, J.H.3
-
176
-
-
84940583132
-
Phospholipids of tumor extracellular vesicles stratify gefitinib-resistant nonsmall cell lung cancer cells from gefitinib-sensitive cells
-
Jung JH, Lee MY, Choi DY, et al. Phospholipids of tumor extracellular vesicles stratify gefitinib-resistant nonsmall cell lung cancer cells from gefitinib-sensitive cells. Proteomics 2015; 15: 824-35.
-
(2015)
Proteomics
, vol.15
, pp. 824-835
-
-
Jung, J.H.1
Lee, M.Y.2
Choi, D.Y.3
-
177
-
-
84896760337
-
Exosomes: Decreased sensitivity of lung cancer A549 cells to cisplatin
-
Xiao X, Yu S, Li S, et al. Exosomes: decreased sensitivity of lung cancer A549 cells to cisplatin. PLoS One 2014; 9: e89534.
-
(2014)
Plos One
, vol.9
-
-
Xiao, X.1
Yu, S.2
Li, S.3
|