Specific direct small molecule p300/β-catenin antagonists maintain stem cell potency

Current Molecular Pharmacology

Volumn 9, Issue 3, 2016, Pages 272-279

  Higuchi, Yusuke ^a,b   Nguyen, Cu ^a   Yasuda, Shin Ya ^a,c   McMillan, Michael ^a   Hasegawa, Kouichi ^c,d   Kahn, Michael ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b OSAKA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

CBP; P300; Peptide mimetics; Pluripotency; Stem cell; Wnt signaling

Indexed keywords

ACYLTRANSFERASE INHIBITOR; BETA CATENIN; E1A ASSOCIATED P300 PROTEIN; N BENZYL 1,2,3,4,8,9 HEXAHYDRO 6 (4 HYDROXYBENZYL) 8 (1 NAPHTHYLMETHYL) 4,7 DIOXO 2H PYRAZINO[1,2 A]PYRIMIDINE 1(6H) CARBOXAMIDE; UNCLASSIFIED DRUG; YH 249; YH 250; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; EP300 PROTEIN, HUMAN; MOLECULAR LIBRARY; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN TARGETING; STEM CELL; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; HEK293 CELL LINE; HUMAN EMBRYONIC STEM CELL; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; PRECLINICAL STUDY; SKELETAL MUSCLE SATELLITE CELL;

ANIMALS; BETA CATENIN; CELL DIFFERENTIATION; CELL LINE; CREB-BINDING PROTEIN; DRUG EVALUATION, PRECLINICAL; E1A-ASSOCIATED P300 PROTEIN; HEK293 CELLS; HUMAN EMBRYONIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; PROTEIN BINDING; SATELLITE CELLS, SKELETAL MUSCLE; SMALL MOLECULE LIBRARIES; STEM CELLS;

EID: 84989221001     PISSN: 18744672     EISSN: 18744702     Source Type: Journal    
DOI: 10.2174/1874467208666150526155146     Document Type: Article

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