Fibroblast Growth Factor Receptor-Mediated Activation of AKT-β-Catenin-CBP Pathway Regulates Survival and Proliferation of Murine Hepatoblasts and Hepatic Tumor Initiating Stem Cells

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Mavila, Nirmala ^a   James, David ^a   Utley, Sarah ^a   Cu, Nguyen ^b,c   Coblens, Orly ^a   Mak, Katrina ^a   Rountree, C Bart ^d   Kahn, Michael ^b,c   Wang, Kasper S ^a  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d St Mary's Hospital Richmond   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA6 INTEGRIN; BETA CATENIN; CD133 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT KERATINOCYTE GROWTH FACTOR; RECOMBINANT PROTEIN; REPIFERMIN; SERINE; TUMOR MARKER; MAT1A PROTEIN, MOUSE; METHIONINE ADENOSYLTRANSFERASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; EX VIVO STUDY; FETUS; INTRACELLULAR SIGNALING; LIVER CELL; LIVER CELL CULTURE; LIVER TUMOR; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; TUMOR PROMOTION; ANIMAL; C57BL MOUSE; CELL CYCLE; CYTOLOGY; HUMAN; LIVER; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

MURINAE;

ANIMALS; BETA CATENIN; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CREB-BINDING PROTEIN; EMBRYONIC STEM CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIVER; LIVER NEOPLASMS; METHIONINE ADENOSYLTRANSFERASE; MICE; MICE, INBRED C57BL; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION;

MLCS; MLOWN;

EID: 84870618348     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050401     Document Type: Article

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