-
1
-
-
76049117463
-
Apoptosis in Candida biofilms exposed to amphotericin B
-
Al-Dhaheri, R. S., and Douglas, L. J. (2010). Apoptosis in Candida biofilms exposed to amphotericin B. J. Med. Microbiol. 59, 149-157. doi: 10.1099/jmm.0.015784-0
-
(2010)
J. Med. Microbiol
, vol.59
, pp. 149-157
-
-
Al-Dhaheri, R.S.1
Douglas, L.J.2
-
2
-
-
84989157334
-
"Fluconazole and MGCD290 in vulvo vaginal candidiasis (VVC): results from a randomized phase II study,"
-
1330 in IDWeek 2013, San Francisco, CA
-
Augenbraun, M., Livingston, J., Parker, R., Lederman, S., Chavoustie, S., Morgan, F., et al. (2013). "Fluconazole and MGCD290 in vulvo vaginal candidiasis (VVC): results from a randomized phase II study," in Poster 1330 in IDWeek 2013, San Francisco, CA.
-
(2013)
Poster
-
-
Augenbraun, M.1
Livingston, J.2
Parker, R.3
Lederman, S.4
Chavoustie, S.5
Morgan, F.6
-
3
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
-
Bitterman, K. J., Anderson, R. M., Cohen, H. Y., Latorre-Esteves, M., and Sinclair, D. A. (2002). Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 277, 45099-45107. doi: 10.1074/jbc. M205670200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
4
-
-
84871502341
-
Hidden killers: human fungal infections
-
Brown, G. D., Denning, D. W., Gow, N. A. R., Levitz, S. M., Netea, M. G., and White, T. C. (2012). Hidden killers: human fungal infections. Sci. Transl. Med. 4, 165rv13. doi: 10.1126/scitranslmed.3004404
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Brown, G.D.1
Denning, D.W.2
Gow, N.A.R.3
Levitz, S.M.4
Netea, M.G.5
White, T.C.6
-
5
-
-
0017886958
-
Sodium butyrate inhibits histone deacetylation in cultured cells
-
Candido, E. P., Reeves, R., and Davie, J. R. (1978). Sodium butyrate inhibits histone deacetylation in cultured cells. Cell 14, 105-113. doi: 10.1016/0092-8674(78)90305-7
-
(1978)
Cell
, vol.14
, pp. 105-113
-
-
Candido, E.P.1
Reeves, R.2
Davie, J.R.3
-
6
-
-
0033607171
-
Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity
-
Carmen, A. A., Griffin, P. R., Calaycay, J. R., Rundlett, S. E., Suka, Y., and Grunstein, M. (1999). Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity. Proc. Natl. Acad. Sci. U.S.A. 96, 12356-12361. doi: 10.1073/pnas.96.22.12356
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 12356-12361
-
-
Carmen, A.A.1
Griffin, P.R.2
Calaycay, J.R.3
Rundlett, S.E.4
Suka, Y.5
Grunstein, M.6
-
7
-
-
25844530060
-
Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi
-
Cowen, L. E., and Lindquist, S. (2005). Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science 309, 2185-2189. doi: 10.1126/science.1118370
-
(2005)
Science
, vol.309
, pp. 2185-2189
-
-
Cowen, L.E.1
Lindquist, S.2
-
8
-
-
84949214078
-
Local and regional chromatin silencing in Candida glabrata: consequences for adhesion and the response to stress
-
De Las Peñas, A., Juárez-Cepeda, J., López-Fuentes, E., Briones-Martín-Del-Campo, M., Gutiérrez-Escobedo, G., and Castaño, I. (2015). Local and regional chromatin silencing in Candida glabrata: consequences for adhesion and the response to stress. FEMS Yeast Res. 15, fov056. doi: 10.1093/femsyr/fov056
-
(2015)
FEMS Yeast Res
, vol.15
-
-
De Las Peñas, A.1
Juárez-Cepeda, J.2
López-Fuentes, E.3
Briones-Martín-Del-Campo, M.4
Gutiérrez-Escobedo, G.5
Castaño, I.6
-
9
-
-
84926058258
-
Infectious disease. How to bolster the antifungal pipeline
-
Denning, D. W., and Bromley, M. J. (2015). Infectious disease. How to bolster the antifungal pipeline. Science 347, 1414-1416. doi: 10.1126/science.aaa6097
-
(2015)
Science
, vol.347
, pp. 1414-1416
-
-
Denning, D.W.1
Bromley, M.J.2
-
10
-
-
17844385918
-
Nicotinic acid limitation regulates silencing of Candida adhesins during UTI
-
Domergue, R., Castaño, I., De Las Peñas, A., Zupancic, M., Lockatell, V., Hebel, J. R., et al. (2005). Nicotinic acid limitation regulates silencing of Candida adhesins during UTI. Science 308, 866-870. doi: 10.1126/science.1108640
-
(2005)
Science
, vol.308
, pp. 866-870
-
-
Domergue, R.1
Castaño, I.2
De Las Peñas, A.3
Zupancic, M.4
Lockatell, V.5
Hebel, J.R.6
-
11
-
-
3042720475
-
Genome evolution in yeasts
-
Dujon, B., Sherman, D., Fischer, G., Durrens, P., Casaregola, S., Lafontaine, I., et al. (2004). Genome evolution in yeasts. Nature 430, 35-44. doi: 10.1038/nature02579
-
(2004)
Nature
, vol.430
, pp. 35-44
-
-
Dujon, B.1
Sherman, D.2
Fischer, G.3
Durrens, P.4
Casaregola, S.5
Lafontaine, I.6
-
12
-
-
31944434598
-
Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans
-
Enjalbert, B., Smith, D. A., Cornell, M. J., Alam, I., Nicholls, S., Brown, A. J. P., et al. (2006). Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans. Mol. Biol. Cell 17, 1018-1032. doi: 10.1091/mbc. E05-06-0501
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 1018-1032
-
-
Enjalbert, B.1
Smith, D.A.2
Cornell, M.J.3
Alam, I.4
Nicholls, S.5
Brown, A.J.P.6
-
13
-
-
84908265816
-
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
-
Falkenberg, K. J., and Johnstone, R. W. (2014). Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat. Rev. Drug Discov. 13, 673-691. doi: 10.1038/nrd4360
-
(2014)
Nat. Rev. Drug Discov
, vol.13
, pp. 673-691
-
-
Falkenberg, K.J.1
Johnstone, R.W.2
-
14
-
-
84960947592
-
Candida albicans repetitive elements display epigenetic diversity and plasticity
-
Freire-Benéitez, V., Price, R. J., Tarrant, D., Berman, J., and Buscaino, A. (2016). Candida albicans repetitive elements display epigenetic diversity and plasticity. Sci. Rep. 6, 22989. doi: 10.1038/srep22989
-
(2016)
Sci. Rep
, vol.6
, pp. 22989
-
-
Freire-Benéitez, V.1
Price, R.J.2
Tarrant, D.3
Berman, J.4
Buscaino, A.5
-
15
-
-
84887264110
-
The deacetylase Sir2 from the yeast Clavispora lusitaniae lacks the evolutionarily conserved capacity to generate subtelomeric heterochromatin
-
Froyd, C. A., Kapoor, S., Dietrich, F., and Rusche, L. N. (2013). The deacetylase Sir2 from the yeast Clavispora lusitaniae lacks the evolutionarily conserved capacity to generate subtelomeric heterochromatin. PLoS Genet. 9:e1003935. doi: 10.1371/journal.pgen.1003935
-
(2013)
PLoS Genet
, vol.9
-
-
Froyd, C.A.1
Kapoor, S.2
Dietrich, F.3
Rusche, L.N.4
-
16
-
-
52449113146
-
Candida albicans, a distinctive fungal model for cellular aging study
-
Fu, X.-H., Meng, F.-L., Hu, Y., and Zhou, J.-Q. (2008). Candida albicans, a distinctive fungal model for cellular aging study. Aging Cell 7, 746-757. doi: 10.1111/j.1474-9726.2008.00424.x
-
(2008)
Aging Cell
, vol.7
, pp. 746-757
-
-
Fu, X.-H.1
Meng, F.-L.2
Hu, Y.3
Zhou, J.-Q.4
-
17
-
-
72449182740
-
Our paths might cross: the role of the fungal cell wall integrity pathway in stress response and cross talk with other stress response pathways
-
Fuchs, B. B., and Mylonakis, E. (2009). Our paths might cross: the role of the fungal cell wall integrity pathway in stress response and cross talk with other stress response pathways. Eukaryot. Cell 8, 1616-1625. doi: 10.1128/EC.00193-09
-
(2009)
Eukaryot. Cell
, vol.8
, pp. 1616-1625
-
-
Fuchs, B.B.1
Mylonakis, E.2
-
18
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Göttlicher, M., Minucci, S., Zhu, P., Krämer, O. H., Schimpf, A., Giavara, S., et al. (2001). Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 20, 6969-6978. doi: 10.1093/emboj/20.24.6969
-
(2001)
EMBO J
, vol.20
, pp. 6969-6978
-
-
Göttlicher, M.1
Minucci, S.2
Zhu, P.3
Krämer, O.H.4
Schimpf, A.5
Giavara, S.6
-
19
-
-
84855872990
-
Candida albicans morphogenesis and host defence: discriminating invasion from colonization
-
Gow, N. A. R., van de Veerdonk, F. L., Brown, A. J. P., and Netea, M. G. (2012). Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat. Rev. Microbiol. 10, 112-122. doi: 10.1038/nrmicro2711
-
(2012)
Nat. Rev. Microbiol
, vol.10
, pp. 112-122
-
-
Gow, N.A.R.1
van de Veerdonk, F.L.2
Brown, A.J.P.3
Netea, M.G.4
-
20
-
-
84884701244
-
Structure of the transcriptional network controlling white-opaque switching in Candida albicans
-
Hernday, A. D., Lohse, M. B., Fordyce, P. M., Nobile, C. J., DeRisi, J. L., and Johnson, A. D. (2013). Structure of the transcriptional network controlling white-opaque switching in Candida albicans. Mol. Microbiol. 90, 22-35. doi: 10.1111/mmi.12329
-
(2013)
Mol. Microbiol
, vol.90
, pp. 22-35
-
-
Hernday, A.D.1
Lohse, M.B.2
Fordyce, P.M.3
Nobile, C.J.4
DeRisi, J.L.5
Johnson, A.D.6
-
21
-
-
84872007065
-
A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis
-
Hnisz, D., Bardet, A. F., Nobile, C. J., Petryshyn, A., Glaser, W., Schöck, U., et al. (2012). A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis. PLoS Genet. 8:e1003118. doi: 10.1371/journal.pgen.1003118
-
(2012)
PLoS Genet
, vol.8
-
-
Hnisz, D.1
Bardet, A.F.2
Nobile, C.J.3
Petryshyn, A.4
Glaser, W.5
Schöck, U.6
-
22
-
-
77954076396
-
The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans
-
Hnisz, D., Majer, O., Frohner, I. E., Komnenovic, V., and Kuchler, K. (2010). The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog. 6:e1000889. doi: 10.1371/journal.ppat.1000889
-
(2010)
PLoS Pathog
, vol.6
-
-
Hnisz, D.1
Majer, O.2
Frohner, I.E.3
Komnenovic, V.4
Kuchler, K.5
-
23
-
-
70350036600
-
Transcriptional loops meet chromatin: a dual-layer network controls white-opaque switching in Candida albicans
-
Hnisz, D., Schwarzmüller, T., and Kuchler, K. (2009). Transcriptional loops meet chromatin: a dual-layer network controls white-opaque switching in Candida albicans. Mol. Microbiol. 74, 1-15. doi: 10.1111/j.1365-2958.2009.06772.x
-
(2009)
Mol. Microbiol
, vol.74
, pp. 1-15
-
-
Hnisz, D.1
Schwarzmüller, T.2
Kuchler, K.3
-
24
-
-
84942856875
-
Regional centromeres in the yeast Candida lusitaniae lack pericentromeric heterochromatin
-
Kapoor, S., Zhu, L., Froyd, C., Liu, T., and Rusche, L. N. (2015). Regional centromeres in the yeast Candida lusitaniae lack pericentromeric heterochromatin. Proc. Natl. Acad. Sci. U.S.A. 112, 12139-12144. doi: 10.1073/pnas.1508749112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. 12139-12144
-
-
Kapoor, S.1
Zhu, L.2
Froyd, C.3
Liu, T.4
Rusche, L.N.5
-
25
-
-
84914811793
-
Functional characterization of Candida albicans Hos2 histone deacetylase
-
Karthikeyan, G., Paul-Satyaseela, M., Dhatchana Moorthy, N., Gopalaswamy, R., and Narayanan, S. (2013). Functional characterization of Candida albicans Hos2 histone deacetylase. F1000Res. 2, 238. doi: 10.12688/f1000research.2-238.v3
-
(2013)
F1000Res
, vol.2
, pp. 238
-
-
Karthikeyan, G.1
Paul-Satyaseela, M.2
Dhatchana Moorthy, N.3
Gopalaswamy, R.4
Narayanan, S.5
-
26
-
-
84949230753
-
Histone deacetylase-mediated morphological transition in Candida albicans
-
Kim, J., Lee, J.-E., and Lee, J.-S. (2015). Histone deacetylase-mediated morphological transition in Candida albicans. J. Microbiol. 53, 805-811. doi: 10.1007/s12275-015-5488-3
-
(2015)
J. Microbiol
, vol.53
, pp. 805-811
-
-
Kim, J.1
Lee, J.-E.2
Lee, J.-S.3
-
27
-
-
84866392310
-
Set3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics
-
Kim, T., Xu, Z., Clauder-Münster, S., Steinmetz, L. M., and Buratowski, S. (2012). Set3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics. Cell 150, 1158-1169. doi: 10.1016/j.cell.2012.08.016
-
(2012)
Cell
, vol.150
, pp. 1158-1169
-
-
Kim, T.1
Xu, Z.2
Clauder-Münster, S.3
Steinmetz, L.M.4
Buratowski, S.5
-
28
-
-
0034971016
-
A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans
-
Klar, A. J., Srikantha, T., and Soll, D. R. (2001). A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. Genetics 158, 919-924.
-
(2001)
Genetics
, vol.158
, pp. 919-924
-
-
Klar, A.J.1
Srikantha, T.2
Soll, D.R.3
-
29
-
-
0030732768
-
Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulence
-
Kvaal, C. A., Srikantha, T., and Soll, D. R. (1997). Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulence. Infect. Immun. 65, 4468-4475.
-
(1997)
Infect. Immun
, vol.65
, pp. 4468-4475
-
-
Kvaal, C.A.1
Srikantha, T.2
Soll, D.R.3
-
30
-
-
0034705129
-
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
-
Landry, J., Sutton, A., Tafrov, S. T., Heller, R. C., Stebbins, J., Pillus, L., et al. (2000). The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc. Natl. Acad. Sci. U.S.A. 97, 5807-5811. doi: 10.1073/pnas.110148297
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
Pillus, L.6
-
31
-
-
84964300533
-
Ssn6 has dual roles in Candida albicans filament development through the interaction with Rpd31
-
Lee, J.-E., Oh, J.-H., Ku, M., Kim, J., Lee, J.-S., and Kang, S.-O. (2015). Ssn6 has dual roles in Candida albicans filament development through the interaction with Rpd31. FEBS Lett. 589, 513-520. doi: 10.1016/j.febslet.2015.01.011
-
(2015)
FEBS Lett
, vol.589
, pp. 513-520
-
-
Lee, J.-E.1
Oh, J.-H.2
Ku, M.3
Kim, J.4
Lee, J.-S.5
Kang, S.-O.6
-
32
-
-
84936943259
-
The Rpd3/Hda1 family of histone deacetylases regulates azole resistance in Candida albicans
-
Li, X., Cai, Q., Mei, H., Zhou, X., Shen, Y., Li, D., et al. (2015). The Rpd3/Hda1 family of histone deacetylases regulates azole resistance in Candida albicans. J. Antimicrob. Chemother. 70, 1993-2003. doi: 10.1093/jac/dkv070
-
(2015)
J. Antimicrob. Chemother
, vol.70
, pp. 1993-2003
-
-
Li, X.1
Cai, Q.2
Mei, H.3
Zhou, X.4
Shen, Y.5
Li, D.6
-
33
-
-
82955168478
-
Drosophila and Galleria insect model hosts
-
Lionakis, M. S. (2011). Drosophila and Galleria insect model hosts. Virulence 2, 521-527. doi: 10.4161/viru.2.6.18520
-
(2011)
Virulence
, vol.2
, pp. 521-527
-
-
Lionakis, M.S.1
-
34
-
-
18844393429
-
Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans
-
Liu, T. T., Lee, R. E. B., Barker, K. S., Lee, R. E., Wei, L., Homayouni, R., et al. (2005). Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans. Antimicrob. Agents Chemother. 49, 2226-2236. doi: 10.1128/AAC.49.6.2226-2236.2005
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 2226-2236
-
-
Liu, T.T.1
Lee, R.E.B.2
Barker, K.S.3
Lee, R.E.4
Wei, L.5
Homayouni, R.6
-
35
-
-
82955247831
-
Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes
-
Lombardi, P. M., Cole, K. E., Dowling, D. P., and Christianson, D. W. (2011). Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes. Curr. Opin. Struct. Biol. 21, 735-743. doi: 10.1016/j.sbi.2011.08.004
-
(2011)
Curr. Opin. Struct. Biol
, vol.21
, pp. 735-743
-
-
Lombardi, P.M.1
Cole, K.E.2
Dowling, D.P.3
Christianson, D.W.4
-
36
-
-
84861205961
-
A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans
-
Lu, Y., Su, C., and Liu, H. (2012). A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans. PLoS Pathog. 8:e1002663. doi: 10.1371/journal.ppat.1002663
-
(2012)
PLoS Pathog
, vol.8
-
-
Lu, Y.1
Su, C.2
Liu, H.3
-
37
-
-
79960921059
-
Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance
-
Lu, Y., Su, C., Wang, A., and Liu, H. (2011). Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance. PLoS Biol. 9:e1001105. doi: 10.1371/journal.pbio.1001105
-
(2011)
PLoS Biol
, vol.9
-
-
Lu, Y.1
Su, C.2
Wang, A.3
Liu, H.4
-
38
-
-
33846056843
-
Entrez Gene: gene-centered information at NCBI
-
Maglott, D., Ostell, J., Pruitt, K. D., and Tatusova, T. (2007). Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 35, D26-D31. doi: 10.1093/nar/gkl993
-
(2007)
Nucleic Acids Res
, vol.35
, pp. D26-D31
-
-
Maglott, D.1
Ostell, J.2
Pruitt, K.D.3
Tatusova, T.4
-
39
-
-
33846938126
-
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans
-
Mai, A., Rotili, D., Massa, S., Brosch, G., Simonetti, G., Passariello, C., et al. (2007). Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans. Bioorg. Med. Chem. Lett. 17, 1221-1225. doi: 10.1016/j.bmcl.2006.12.028
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 1221-1225
-
-
Mai, A.1
Rotili, D.2
Massa, S.3
Brosch, G.4
Simonetti, G.5
Passariello, C.6
-
40
-
-
84906935477
-
Resistance of Candida spp. to antifungal drugs in the ICU: where are we now?
-
Maubon, D., Garnaud, C., Calandra, T., Sanglard, D., and Cornet, M. (2014). Resistance of Candida spp. to antifungal drugs in the ICU: where are we now? Intensive Care Med. 40, 1241-1255. doi: 10.1007/s00134-014-3404-7
-
(2014)
Intensive Care Med
, vol.40
, pp. 1241-1255
-
-
Maubon, D.1
Garnaud, C.2
Calandra, T.3
Sanglard, D.4
Cornet, M.5
-
41
-
-
73749084037
-
Regulation of multidrug resistance in pathogenic fungi
-
Morschhäuser, J. (2010). Regulation of multidrug resistance in pathogenic fungi. Fungal Genet. Biol. 47, 94-106. doi: 10.1016/j.fgb.2009.08.002
-
(2010)
Fungal Genet. Biol
, vol.47
, pp. 94-106
-
-
Morschhäuser, J.1
-
42
-
-
84929598341
-
Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents
-
Mottamal, M., Zheng, S., Huang, T. L., and Wang, G. (2015). Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents. Mol. Basel Switz. 20, 3898-3941. doi: 10.3390/molecules20033898
-
(2015)
Mol. Basel Switz
, vol.20
, pp. 3898-3941
-
-
Mottamal, M.1
Zheng, S.2
Huang, T.L.3
Wang, G.4
-
43
-
-
84903954203
-
A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans
-
Nobile, C. J., Fox, E. P., Hartooni, N., Mitchell, K. F., Hnisz, D., Andes, D. R., et al. (2014). A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans. mBio 5, e01201-e1214. doi: 10.1128/mBio.01201-14
-
(2014)
mBio
, vol.5
-
-
Nobile, C.J.1
Fox, E.P.2
Hartooni, N.3
Mitchell, K.F.4
Hnisz, D.5
Andes, D.R.6
-
44
-
-
84856117019
-
A recently evolved transcriptional network controls biofilm development in Candida albicans
-
Nobile, C. J., Fox, E. P., Nett, J. E., Sorrells, T. R., Mitrovich, Q. M., Hernday, A. D., et al. (2012). A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell 148, 126-138. doi: 10.1016/j.cell.2011.10.048
-
(2012)
Cell
, vol.148
, pp. 126-138
-
-
Nobile, C.J.1
Fox, E.P.2
Nett, J.E.3
Sorrells, T.R.4
Mitrovich, Q.M.5
Hernday, A.D.6
-
45
-
-
84879009054
-
Local silencing controls the oxidative stress response and the multidrug resistance in Candida glabrata
-
Orta-Zavalza, E., Guerrero-Serrano, G., Gutiérrez-Escobedo, G., Cañas-Villamar, I., Juárez-Cepeda, J., Castaño, I., et al. (2013). Local silencing controls the oxidative stress response and the multidrug resistance in Candida glabrata. Mol. Microbiol. 88, 1135-1148. doi: 10.1111/mmi.12247
-
(2013)
Mol. Microbiol
, vol.88
, pp. 1135-1148
-
-
Orta-Zavalza, E.1
Guerrero-Serrano, G.2
Gutiérrez-Escobedo, G.3
Cañas-Villamar, I.4
Juárez-Cepeda, J.5
Castaño, I.6
-
46
-
-
0343199707
-
Phenotypic switching in Candida albicans is controlled by a SIR2 gene
-
Pérez-Martín, J., Uría, J. A., and Johnson, A. D. (1999). Phenotypic switching in Candida albicans is controlled by a SIR2 gene. EMBO J. 18, 2580-2592. doi: 10.1093/emboj/18.9.2580
-
(1999)
EMBO J
, vol.18
, pp. 2580-2592
-
-
Pérez-Martín, J.1
Uría, J.A.2
Johnson, A.D.3
-
47
-
-
84956627660
-
Update on antifungal drug resistance
-
Perlin, D. S., Shor, E., and Zhao, Y. (2015). Update on antifungal drug resistance. Curr. Clin. Microbiol. Rep. 2, 84-95. doi: 10.1007/s40588-015-0015-1
-
(2015)
Curr. Clin. Microbiol. Rep
, vol.2
, pp. 84-95
-
-
Perlin, D.S.1
Shor, E.2
Zhao, Y.3
-
48
-
-
71549146873
-
Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens
-
Pfaller, M. A., Messer, S. A., Georgopapadakou, N., Martell, L. A., Besterman, J. M., and Diekema, D. J. (2009). Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens. J. Clin. Microbiol. 47, 3797-3804. doi: 10.1128/JCM.00618-09
-
(2009)
J. Clin. Microbiol
, vol.47
, pp. 3797-3804
-
-
Pfaller, M.A.1
Messer, S.A.2
Georgopapadakou, N.3
Martell, L.A.4
Besterman, J.M.5
Diekema, D.J.6
-
49
-
-
84925041893
-
In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species
-
Pfaller, M. A., Rhomberg, P. R., Messer, S. A., and Castanheira, M. (2015). In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species. Diagn. Microbiol. Infect. Dis. 81, 259-263. doi: 10.1016/j.diagmicrobio.2014.11.008
-
(2015)
Diagn. Microbiol. Infect. Dis
, vol.81
, pp. 259-263
-
-
Pfaller, M.A.1
Rhomberg, P.R.2
Messer, S.A.3
Castanheira, M.4
-
50
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel, C. J., Zhang, F., Huang, E. Y., Guenther, M. G., Lazar, M. A., and Klein, P. S. (2001). Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J. Biol. Chem. 276, 36734-36741. doi: 10.1074/jbc. M101287200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
51
-
-
84928210701
-
Candida survival strategies
-
Polke, M., Hube, B., and Jacobsen, I. D. (2015). Candida survival strategies. Adv. Appl. Microbiol. 91, 139-235. doi: 10.1016/bs.aambs.2014.12.002
-
(2015)
Adv. Appl. Microbiol
, vol.91
, pp. 139-235
-
-
Polke, M.1
Hube, B.2
Jacobsen, I.D.3
-
52
-
-
84866148796
-
Functional genomic analysis of Candida glabrata-macrophage interaction: role of chromatin remodeling in virulence
-
Rai, M. N., Balusu, S., Gorityala, N., Dandu, L., and Kaur, R. (2012). Functional genomic analysis of Candida glabrata-macrophage interaction: role of chromatin remodeling in virulence. PLoS Pathog. 8:e1002863. doi: 10.1371/journal.ppat.1002863
-
(2012)
PLoS Pathog
, vol.8
-
-
Rai, M.N.1
Balusu, S.2
Gorityala, N.3
Dandu, L.4
Kaur, R.5
-
53
-
-
84936944430
-
Synergy of flavonoids with HDAC inhibitor: new approach to target Candida tropicalis biofilms
-
Rajasekharan, S. K., Ramesh, S., and Bakkiyaraj, D. (2015). Synergy of flavonoids with HDAC inhibitor: new approach to target Candida tropicalis biofilms. J. Chemother. 27, 246-249. doi: 10.1179/1973947814Y.0000000186
-
(2015)
J. Chemother
, vol.27
, pp. 246-249
-
-
Rajasekharan, S.K.1
Ramesh, S.2
Bakkiyaraj, D.3
-
54
-
-
84868125083
-
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance
-
Robbins, N., Leach, M. D., and Cowen, L. E. (2012). Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. Cell Rep. 2, 878-888. doi: 10.1016/j.celrep.2012.08.035
-
(2012)
Cell Rep
, vol.2
, pp. 878-888
-
-
Robbins, N.1
Leach, M.D.2
Cowen, L.E.3
-
55
-
-
79251554670
-
Histone deacetylase inhibitors impair innate immune responses to toll-like receptor agonists and to infection
-
Roger, T., Lugrin, J., Le Roy, D., Goy, G., Mombelli, M., Koessler, T., et al. (2011). Histone deacetylase inhibitors impair innate immune responses to toll-like receptor agonists and to infection. Blood 117, 1205-1217. doi: 10.1182/blood-2010-05-284711
-
(2011)
Blood
, vol.117
, pp. 1205-1217
-
-
Roger, T.1
Lugrin, J.2
Le Roy, D.3
Goy, G.4
Mombelli, M.5
Koessler, T.6
-
56
-
-
0029856225
-
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription
-
Rundlett, S. E., Carmen, A. A., Kobayashi, R., Bavykin, S., Turner, B. M., and Grunstein, M. (1996). HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl. Acad. Sci. U.S.A. 93, 14503-14508. doi: 10.1073/pnas.93.25.14503
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 14503-14508
-
-
Rundlett, S.E.1
Carmen, A.A.2
Kobayashi, R.3
Bavykin, S.4
Turner, B.M.5
Grunstein, M.6
-
57
-
-
33846709501
-
Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes
-
Sanders, B. D., Zhao, K., Slama, J. T., and Marmorstein, R. (2007). Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes. Mol. Cell 25, 463-472. doi: 10.1016/j.molcel.2006.12.022
-
(2007)
Mol. Cell
, vol.25
, pp. 463-472
-
-
Sanders, B.D.1
Zhao, K.2
Slama, J.T.3
Marmorstein, R.4
-
58
-
-
84926472334
-
Coping with stress and the emergence of multidrug resistance in fungi
-
Shor, E., and Perlin, D. S. (2015). Coping with stress and the emergence of multidrug resistance in fungi. PLoS Pathog. 11:e1004668. doi: 10.1371/journal.ppat.1004668
-
(2015)
PLoS Pathog
, vol.11
-
-
Shor, E.1
Perlin, D.S.2
-
59
-
-
35448985401
-
Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans
-
Simonetti, G., Passariello, C., Rotili, D., Mai, A., Garaci, E., and Palamara, A. T. (2007). Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans. FEMS Yeast Res. 7, 1371-1380. doi: 10.1111/j.1567-1364.2007.00276.x
-
(2007)
FEMS Yeast Res
, vol.7
, pp. 1371-1380
-
-
Simonetti, G.1
Passariello, C.2
Rotili, D.3
Mai, A.4
Garaci, E.5
Palamara, A.T.6
-
60
-
-
79960125707
-
Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans
-
Singh, R. P., Prasad, H. K., Sinha, I., Agarwal, N., and Natarajan, K. (2011). Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans. J. Biol. Chem. 286, 25154-25170. doi: 10.1074/jbc. M111.233569
-
(2011)
J. Biol. Chem
, vol.286
, pp. 25154-25170
-
-
Singh, R.P.1
Prasad, H.K.2
Sinha, I.3
Agarwal, N.4
Natarajan, K.5
-
61
-
-
0036841830
-
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation
-
Smith, W. L., and Edlind, T. D. (2002). Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. Antimicrob. Agents Chemother. 46, 3532-3539. doi: 10.1128/AAC.46.11.3532-3539.2002
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 3532-3539
-
-
Smith, W.L.1
Edlind, T.D.2
-
62
-
-
3142562372
-
Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases
-
Somoza, J. R., Skene, R. J., Katz, B. A., Mol, C., Ho, J. D., Jennings, A. J., et al. (2004). Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases. Structure 12, 1325-1334. doi: 10.1016/j.str.2004.04.012
-
(2004)
Structure
, vol.12
, pp. 1325-1334
-
-
Somoza, J.R.1
Skene, R.J.2
Katz, B.A.3
Mol, C.4
Ho, J.D.5
Jennings, A.J.6
-
63
-
-
0034932733
-
The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans
-
Srikantha, T., Tsai, L., Daniels, K., Klar, A. J., and Soll, D. R. (2001). The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans. J. Bacteriol. 183, 4614-4625. doi: 10.1128/JB.183.15.4614-4625.2001
-
(2001)
J. Bacteriol
, vol.183
, pp. 4614-4625
-
-
Srikantha, T.1
Tsai, L.2
Daniels, K.3
Klar, A.J.4
Soll, D.R.5
-
64
-
-
80051571474
-
Regulation of white and opaque cell-type formation in Candida albicans by Rtt109 and Hst3
-
Stevenson, J. S., and Liu, H. (2011). Regulation of white and opaque cell-type formation in Candida albicans by Rtt109 and Hst3. Mol. Microbiol. 81, 1078-1091. doi: 10.1111/j.1365-2958.2011.07754.x
-
(2011)
Mol. Microbiol
, vol.81
, pp. 1078-1091
-
-
Stevenson, J.S.1
Liu, H.2
-
65
-
-
84875516407
-
Nucleosome assembly factors CAF-1 and HIR modulate epigenetic switching frequencies in an H3K56 acetylation-associated manner in Candida albicans
-
Stevenson, J. S., and Liu, H. (2013). Nucleosome assembly factors CAF-1 and HIR modulate epigenetic switching frequencies in an H3K56 acetylation-associated manner in Candida albicans. Eukaryot. Cell 12, 591-603. doi: 10.1128/EC.00334-12
-
(2013)
Eukaryot. Cell
, vol.12
, pp. 591-603
-
-
Stevenson, J.S.1
Liu, H.2
-
66
-
-
80052965456
-
Growth of Candida albicans hyphae
-
Sudbery, P. E. (2011). Growth of Candida albicans hyphae. Nat. Rev. Microbiol. 9, 737-748. doi: 10.1038/nrmicro2636
-
(2011)
Nat. Rev. Microbiol
, vol.9
, pp. 737-748
-
-
Sudbery, P.E.1
-
67
-
-
84885002728
-
Mechanisms of Candida biofilm drug resistance
-
Taff, H. T., Mitchell, K. F., Edward, J. A., and Andes, D. R. (2013). Mechanisms of Candida biofilm drug resistance. Future Microbiol. 8, 1325-1337. doi: 10.2217/fmb.13.101
-
(2013)
Future Microbiol
, vol.8
, pp. 1325-1337
-
-
Taff, H.T.1
Mitchell, K.F.2
Edward, J.A.3
Andes, D.R.4
-
68
-
-
0344874578
-
Histone deacetylases in fungi: novel members, new facts
-
Trojer, P., Brandtner, E. M., Brosch, G., Loidl, P., Galehr, J., Linzmaier, R., et al. (2003). Histone deacetylases in fungi: novel members, new facts. Nucleic Acids Res. 31, 3971-3981. doi: 10.1093/nar/gkg473
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3971-3981
-
-
Trojer, P.1
Brandtner, E.M.2
Brosch, G.3
Loidl, P.4
Galehr, J.5
Linzmaier, R.6
-
69
-
-
84946099005
-
The Candida albicans histone acetyltransferase Hat1 regulates stress resistance and virulence via distinct chromatin assembly pathways
-
Tscherner, M., Zwolanek, F., Jenull, S., Sedlazeck, F. J., Petryshyn, A., Frohner, I. E., et al. (2015). The Candida albicans histone acetyltransferase Hat1 regulates stress resistance and virulence via distinct chromatin assembly pathways. PLoS Pathog. 11:e1005218. doi: 10.1371/journal.ppat.1005218
-
(2015)
PLoS Pathog
, vol.11
-
-
Tscherner, M.1
Zwolanek, F.2
Jenull, S.3
Sedlazeck, F.J.4
Petryshyn, A.5
Frohner, I.E.6
-
70
-
-
0017284850
-
A new antifungal antibiotic, trichostatin
-
Tsuji, N., Kobayashi, M., Nagashima, K., Wakisaka, Y., and Koizumi, K. (1976). A new antifungal antibiotic, trichostatin. J. Antibiot. 29, 1-6. doi: 10.7164/antibiotics.29.1
-
(1976)
J. Antibiot
, vol.29
, pp. 1-6
-
-
Tsuji, N.1
Kobayashi, M.2
Nagashima, K.3
Wakisaka, Y.4
Koizumi, K.5
-
71
-
-
0037507285
-
Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans
-
Uhl, M. A., Biery, M., Craig, N., and Johnson, A. D. (2003). Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans. EMBO J. 22, 2668-2678. doi: 10.1093/emboj/cdg256
-
(2003)
EMBO J
, vol.22
, pp. 2668-2678
-
-
Uhl, M.A.1
Biery, M.2
Craig, N.3
Johnson, A.D.4
-
72
-
-
77957784499
-
The transcriptional regulator Nrg1p controls Candida albicans biofilm formation and dispersion
-
Uppuluri, P., Pierce, C. G., Thomas, D. P., Bubeck, S. S., Saville, S. P., and Lopez-Ribot, J. L. (2010). The transcriptional regulator Nrg1p controls Candida albicans biofilm formation and dispersion. Eukaryot. Cell 9, 1531-1537. doi: 10.1128/EC.00111-10
-
(2010)
Eukaryot. Cell
, vol.9
, pp. 1531-1537
-
-
Uppuluri, P.1
Pierce, C.G.2
Thomas, D.P.3
Bubeck, S.S.4
Saville, S.P.5
Lopez-Ribot, J.L.6
-
73
-
-
77954541309
-
Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy
-
Wurtele, H., Tsao, S., Lépine, G., Mullick, A., Tremblay, J., Drogaris, P., et al. (2010). Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy. Nat. Med. 16, 774-780. doi: 10.1038/nm.2175
-
(2010)
Nat. Med
, vol.16
, pp. 774-780
-
-
Wurtele, H.1
Tsao, S.2
Lépine, G.3
Mullick, A.4
Tremblay, J.5
Drogaris, P.6
-
74
-
-
0024996768
-
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
-
Yoshida, M., Kijima, M., Akita, M., and Beppu, T. (1990). Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J. Biol. Chem. 265, 17174-17179.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 17174-17179
-
-
Yoshida, M.1
Kijima, M.2
Akita, M.3
Beppu, T.4
-
75
-
-
0023195737
-
Effects of trichostatins on differentiation of murine erythroleukemia cells
-
Yoshida, M., Nomura, S., and Beppu, T. (1987). Effects of trichostatins on differentiation of murine erythroleukemia cells. Cancer Res. 47, 3688-3691.
-
(1987)
Cancer Res
, vol.47
, pp. 3688-3691
-
-
Yoshida, M.1
Nomura, S.2
Beppu, T.3
-
76
-
-
77957872097
-
HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis
-
Zacchi, L. F., Schulz, W. L., and Davis, D. A. (2010). HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis. PLoS ONE 5:e12171. doi: 10.1371/journal.pone.0012171
-
(2010)
PLoS ONE
, vol.5
-
-
Zacchi, L.F.1
Schulz, W.L.2
Davis, D.A.3
-
77
-
-
84922357701
-
Histone deacetylase inhibitors for enhancing activity of antifungal agent: a patent evaluation of WO2014041424(A1)
-
Zhang, L., and Xu, W. (2015). Histone deacetylase inhibitors for enhancing activity of antifungal agent: a patent evaluation of WO2014041424(A1). Expert Opin. Ther. Pat. 25, 237-240. doi: 10.1517/13543776.2014.981256
-
(2015)
Expert Opin. Ther. Pat
, vol.25
, pp. 237-240
-
-
Zhang, L.1
Xu, W.2
|