-
1
-
-
84878342622
-
Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations
-
Alexander B.D., Johnson M.D., Pfeiffer C.D., Jimenez-Ortigosa C., Catania J., Booker R., Castanheira M., Messer S.A., Perlin D.S., Pfaller M.A. Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations. Clin Infect Dis 2013, 56:1724-1732.
-
(2013)
Clin Infect Dis
, vol.56
, pp. 1724-1732
-
-
Alexander, B.D.1
Johnson, M.D.2
Pfeiffer, C.D.3
Jimenez-Ortigosa, C.4
Catania, J.5
Booker, R.6
Castanheira, M.7
Messer, S.A.8
Perlin, D.S.9
Pfaller, M.A.10
-
2
-
-
84880509446
-
Epidemiological changes with potential implication for antifungal prescription recommendations for fungaemia: data from a nationwide fungaemia surveillance programme
-
Arendrup M.C., Dzajic E., Jensen R.H., Johansen H.K., Kjaeldgaard P., Knudsen J.D., Kristensen L., Leitz C., Lemming L.E., Nielsen L., Olesen B., Rosenvinge F.S., Roder B.L., Schonheyder H.C. Epidemiological changes with potential implication for antifungal prescription recommendations for fungaemia: data from a nationwide fungaemia surveillance programme. Clin Microbiol Infect 2013, 19:E343-E353.
-
(2013)
Clin Microbiol Infect
, vol.19
, pp. E343-E353
-
-
Arendrup, M.C.1
Dzajic, E.2
Jensen, R.H.3
Johansen, H.K.4
Kjaeldgaard, P.5
Knudsen, J.D.6
Kristensen, L.7
Leitz, C.8
Lemming, L.E.9
Nielsen, L.10
Olesen, B.11
Rosenvinge, F.S.12
Roder, B.L.13
Schonheyder, H.C.14
-
3
-
-
77952648499
-
Low prevalence of fks1 hotspot 1 mutations in a worldwide collection of Candida spp
-
Castanheira M., Woosley L.N., Pfaller M.A., Diekema D.J., Messer S.A., Jones R.N. Low prevalence of fks1 hotspot 1 mutations in a worldwide collection of Candida spp. Antimicrob Agents Chemother 2010, 54:2655-2659.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2655-2659
-
-
Castanheira, M.1
Woosley, L.N.2
Pfaller, M.A.3
Diekema, D.J.4
Messer, S.A.5
Jones, R.N.6
-
4
-
-
84891506996
-
Frequency of fks mutations among Candida glabrata isolates from a 10-year global collection of bloodstream infection isolates
-
Castanheira M., Woosley L.N., Messer S.A., Diekema D.J., Jones R.N., Pfaller M.A. Frequency of fks mutations among Candida glabrata isolates from a 10-year global collection of bloodstream infection isolates. Antimicrob Agents Chemother 2014, 58:577-580.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 577-580
-
-
Castanheira, M.1
Woosley, L.N.2
Messer, S.A.3
Diekema, D.J.4
Jones, R.N.5
Pfaller, M.A.6
-
5
-
-
42049112162
-
Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei
-
Chaturvedi V., Ramani R., Ghannoum M.A., Killian S.B., Holliday N., Knapp C., Ostrosky-Zeichner L., Messer S.A., Pfaller M.A., Iqbal N.J., Arthington-Skaggs B.A., Vazquez J.A., Sein T., Rex J.H., Walsh T.J. Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei. Antimicrob Agents Chemother 2008, 52:1500-1502.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1500-1502
-
-
Chaturvedi, V.1
Ramani, R.2
Ghannoum, M.A.3
Killian, S.B.4
Holliday, N.5
Knapp, C.6
Ostrosky-Zeichner, L.7
Messer, S.A.8
Pfaller, M.A.9
Iqbal, N.J.10
Arthington-Skaggs, B.A.11
Vazquez, J.A.12
Sein, T.13
Rex, J.H.14
Walsh, T.J.15
-
8
-
-
25844530060
-
Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi
-
Cowen L.E., Lindquist S. Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science 2005, 309:2185-2189.
-
(2005)
Science
, vol.309
, pp. 2185-2189
-
-
Cowen, L.E.1
Lindquist, S.2
-
9
-
-
8844219662
-
Combinations of antifungal agents in therapy-what value are they?
-
Cuenca-Estrella M. Combinations of antifungal agents in therapy-what value are they?. J Antimicrob Chemother 2004, 54:854-869.
-
(2004)
J Antimicrob Chemother
, vol.54
, pp. 854-869
-
-
Cuenca-Estrella, M.1
-
10
-
-
84856576829
-
Candida spp. with acquired echinocandin resistance, France, 2004-2010
-
Dannaoui E., Desnos-Ollivier M., Garcia-Hermoso D., Grenouillet F., Cassaing S., Baixench M.T., Bretagne S., Dromer F., Lortholary O. Candida spp. with acquired echinocandin resistance, France, 2004-2010. Emerg Infect Dis 2012, 18:86-90.
-
(2012)
Emerg Infect Dis
, vol.18
, pp. 86-90
-
-
Dannaoui, E.1
Desnos-Ollivier, M.2
Garcia-Hermoso, D.3
Grenouillet, F.4
Cassaing, S.5
Baixench, M.T.6
Bretagne, S.7
Dromer, F.8
Lortholary, O.9
-
11
-
-
70349127708
-
Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint
-
Garcia-Effron G., Lee S., Park S., Cleary J.D., Perlin D.S. Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint. Antimicrob Agents Chemother 2009, 53:3690-3699.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3690-3699
-
-
Garcia-Effron, G.1
Lee, S.2
Park, S.3
Cleary, J.D.4
Perlin, D.S.5
-
12
-
-
77951243444
-
Novel FKS mutations associated with echinocandin resistance in Candida species
-
Garcia-Effron G., Chua D.J., Tomada J.R., DiPersio J., Perlin D.S., Ghannoum M., Bonilla H. Novel FKS mutations associated with echinocandin resistance in Candida species. Antimicrob Agents Chemother 2010, 54:2225-2227.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2225-2227
-
-
Garcia-Effron, G.1
Chua, D.J.2
Tomada, J.R.3
DiPersio, J.4
Perlin, D.S.5
Ghannoum, M.6
Bonilla, H.7
-
13
-
-
0036008097
-
Deacetylase enzymes: biological functions and the use of small-molecule inhibitors
-
Grozinger C.M., Schreiber S.L. Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. Chem Biol 2002, 9:3-16.
-
(2002)
Chem Biol
, vol.9
, pp. 3-16
-
-
Grozinger, C.M.1
Schreiber, S.L.2
-
14
-
-
0030798245
-
Histone acetylation in chromatin structure and transcription
-
Grunstein M. Histone acetylation in chromatin structure and transcription. Nature 1997, 389:349-352.
-
(1997)
Nature
, vol.389
, pp. 349-352
-
-
Grunstein, M.1
-
15
-
-
84867469852
-
CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction
-
Healey K.R., Katiyar S.K., Raj S., Edlind T.D. CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction. Mol Microbiol 2012, 86:303-313.
-
(2012)
Mol Microbiol
, vol.86
, pp. 303-313
-
-
Healey, K.R.1
Katiyar, S.K.2
Raj, S.3
Edlind, T.D.4
-
16
-
-
25844450827
-
Cell biology. A fungal Achilles' heel
-
Heitman J. Cell biology. A fungal Achilles' heel. Science 2005, 309:2175-2176.
-
(2005)
Science
, vol.309
, pp. 2175-2176
-
-
Heitman, J.1
-
17
-
-
1442275740
-
Combination antifungal therapy
-
Johnson M.D., MacDougall C., Ostrosky-Zeichner L., Perfect J.R., Rex J.H. Combination antifungal therapy. Antimicrob Agents Chemother 2004, 48:693-715.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 693-715
-
-
Johnson, M.D.1
MacDougall, C.2
Ostrosky-Zeichner, L.3
Perfect, J.R.4
Rex, J.H.5
-
18
-
-
40349098920
-
Chemosensitization of fungal pathogens to antimicrobial agents using benzo analogs
-
Kim J.H., Mahoney N., Chan K.L., Molyneux R.J., May G.S., Campbell B.C. Chemosensitization of fungal pathogens to antimicrobial agents using benzo analogs. FEMS Microbiol Lett 2008, 281:64-72.
-
(2008)
FEMS Microbiol Lett
, vol.281
, pp. 64-72
-
-
Kim, J.H.1
Mahoney, N.2
Chan, K.L.3
Molyneux, R.J.4
May, G.S.5
Campbell, B.C.6
-
19
-
-
84868014787
-
Optimizing echinocandin dosing and susceptibility breakpoint determination via in vivo pharmacodynamic evaluation against Candida glabrata with and without fks mutations
-
Lepak A., Castanheira M., Diekema D., Pfaller M., Andes D. Optimizing echinocandin dosing and susceptibility breakpoint determination via in vivo pharmacodynamic evaluation against Candida glabrata with and without fks mutations. Antimicrob Agents Chemother 2012, 56:5875-5882.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 5875-5882
-
-
Lepak, A.1
Castanheira, M.2
Diekema, D.3
Pfaller, M.4
Andes, D.5
-
20
-
-
40049091962
-
In vitro interaction between azoles and cyclosporin A against clinical isolates of Candida albicans determined by the chequerboard method and time-kill curves
-
Li Y., Sun S., Guo Q., Ma L., Shi C., Su L., Li H. In vitro interaction between azoles and cyclosporin A against clinical isolates of Candida albicans determined by the chequerboard method and time-kill curves. J Antimicrob Chemother 2008, 61:577-585.
-
(2008)
J Antimicrob Chemother
, vol.61
, pp. 577-585
-
-
Li, Y.1
Sun, S.2
Guo, Q.3
Ma, L.4
Shi, C.5
Su, L.6
Li, H.7
-
21
-
-
33846938126
-
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans
-
Mai A., Rotili D., Massa S., Brosch G., Simonetti G., Passariello C., Palamara A.T. Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans. Bioorg Med Chem Lett 2007, 17:1221-1225.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 1221-1225
-
-
Mai, A.1
Rotili, D.2
Massa, S.3
Brosch, G.4
Simonetti, G.5
Passariello, C.6
Palamara, A.T.7
-
22
-
-
0037636527
-
Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90
-
Matthews R.C., Rigg G., Hodgetts S., Carter T., Chapman C., Gregory C., Illidge C., Burnie J. Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90. Antimicrob Agents Chemother 2003, 47:2208-2216.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 2208-2216
-
-
Matthews, R.C.1
Rigg, G.2
Hodgetts, S.3
Carter, T.4
Chapman, C.5
Gregory, C.6
Illidge, C.7
Burnie, J.8
-
24
-
-
0001986819
-
Synergism testing. Broth microdilution, checkerboard, and broth macrodilution methods
-
American Society for Microbiology, Washington, DC
-
Moody J.A. Synergism testing. Broth microdilution, checkerboard, and broth macrodilution methods. Clinical Microbiology Procedures Hndbook 1991, vol. 1:5.18.1-5.18.28. American Society for Microbiology, Washington, DC.
-
(1991)
Clinical Microbiology Procedures Hndbook
, vol.1
, pp. 5.18.1-5.18.28
-
-
Moody, J.A.1
-
25
-
-
23844522610
-
Histone deacetylase inhibitors: latest developments, trends and prospects
-
Moradei O., Maroun C.R., Paquin I., Vaisburg A. Histone deacetylase inhibitors: latest developments, trends and prospects. Curr Med Chem Anticancer Agents 2005, 5:529-560.
-
(2005)
Curr Med Chem Anticancer Agents
, vol.5
, pp. 529-560
-
-
Moradei, O.1
Maroun, C.R.2
Paquin, I.3
Vaisburg, A.4
-
26
-
-
84878319377
-
Candida glabrata and FKS mutations: witnessing the emergence of the true multidrug-resistant Candida
-
Ostrosky-Zeichner L. Candida glabrata and FKS mutations: witnessing the emergence of the true multidrug-resistant Candida. Clin Infect Dis 2013, 56:1733-1734.
-
(2013)
Clin Infect Dis
, vol.56
, pp. 1733-1734
-
-
Ostrosky-Zeichner, L.1
-
27
-
-
60549098868
-
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America
-
Pappas P.G., Kauffman C.A., Andes D., Benjamin D.K., Calandra T.F., Edwards J.E., Filler S.G., Fisher J.F., Kullberg B.J., Ostrosky-Zeichner L., Reboli A.C., Rex J.H., Walsh T.J., Sobel J.D. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009, 48:503-535.
-
(2009)
Clin Infect Dis
, vol.48
, pp. 503-535
-
-
Pappas, P.G.1
Kauffman, C.A.2
Andes, D.3
Benjamin, D.K.4
Calandra, T.F.5
Edwards, J.E.6
Filler, S.G.7
Fisher, J.F.8
Kullberg, B.J.9
Ostrosky-Zeichner, L.10
Reboli, A.C.11
Rex, J.H.12
Walsh, T.J.13
Sobel, J.D.14
-
28
-
-
80755153763
-
Echinocandin-resistant Candida: Molecular methods and phenotypes
-
Perlin D.S. Echinocandin-resistant Candida: Molecular methods and phenotypes. Curr Fungal Infect Rep 2011, 5:113-119.
-
(2011)
Curr Fungal Infect Rep
, vol.5
, pp. 113-119
-
-
Perlin, D.S.1
-
29
-
-
38949191482
-
Azole antifungal drug cross-resistance: mechanisms epidemiology, and clinical significance
-
Pfaller M.A., Diekema D.J. Azole antifungal drug cross-resistance: mechanisms epidemiology, and clinical significance. J Invasive Fungal Infect 2007, 1:74-92.
-
(2007)
J Invasive Fungal Infect
, vol.1
, pp. 74-92
-
-
Pfaller, M.A.1
Diekema, D.J.2
-
30
-
-
84865165327
-
Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012
-
Pfaller M.A., Diekema D.J. Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012. J Clin Microbiol 2012, 50:2846-2856.
-
(2012)
J Clin Microbiol
, vol.50
, pp. 2846-2856
-
-
Pfaller, M.A.1
Diekema, D.J.2
-
31
-
-
71549146873
-
Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens
-
Pfaller M.A., Messer S.A., Georgopapadakou N., Martell L.A., Besterman J.M., Diekema D.J. Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens. J Clin Microbiol 2009, 47:3797-3804.
-
(2009)
J Clin Microbiol
, vol.47
, pp. 3797-3804
-
-
Pfaller, M.A.1
Messer, S.A.2
Georgopapadakou, N.3
Martell, L.A.4
Besterman, J.M.5
Diekema, D.J.6
-
32
-
-
84863337736
-
Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata
-
Pfaller M.A., Castanheira M., Lockhart S.R., Ahlquist A.M., Messer S.A., Jones R.N. Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata. J Clin Microbiol 2012, 50:1199-1203.
-
(2012)
J Clin Microbiol
, vol.50
, pp. 1199-1203
-
-
Pfaller, M.A.1
Castanheira, M.2
Lockhart, S.R.3
Ahlquist, A.M.4
Messer, S.A.5
Jones, R.N.6
-
33
-
-
84880631469
-
Echinocandin and triazole antifungal susceptibility profiles of opportunistic yeast and mould clinical isolates (2010-2011); application of new CLSI clinical breakpoints and epidemiological cutoff values to characterize geographic and temporal trends of antifungal resistance
-
Pfaller M.A., Messer S.A., Woosley L.N., Jones R.N., Castanheira M. Echinocandin and triazole antifungal susceptibility profiles of opportunistic yeast and mould clinical isolates (2010-2011); application of new CLSI clinical breakpoints and epidemiological cutoff values to characterize geographic and temporal trends of antifungal resistance. J Clin Microbiol 2013, 51:2571-2581.
-
(2013)
J Clin Microbiol
, vol.51
, pp. 2571-2581
-
-
Pfaller, M.A.1
Messer, S.A.2
Woosley, L.N.3
Jones, R.N.4
Castanheira, M.5
-
34
-
-
77954444121
-
Breakthrough invasive candidiasis in patients on micafungin
-
Pfeiffer C.D., Garcia-Effron G., Zaas A.K., Perfect J.R., Perlin D.S., Alexander B.D. Breakthrough invasive candidiasis in patients on micafungin. J Clin Microbiol 2010, 48:2373-2380.
-
(2010)
J Clin Microbiol
, vol.48
, pp. 2373-2380
-
-
Pfeiffer, C.D.1
Garcia-Effron, G.2
Zaas, A.K.3
Perfect, J.R.4
Perlin, D.S.5
Alexander, B.D.6
-
35
-
-
84868125083
-
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance
-
Robbins N., Leach M.D., Cowen L.E. Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. Cell Rep 2012, 2:878-888.
-
(2012)
Cell Rep
, vol.2
, pp. 878-888
-
-
Robbins, N.1
Leach, M.D.2
Cowen, L.E.3
-
36
-
-
0036488166
-
Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences
-
Sanglard D., Odds F.C. Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. Lancet Infect Dis 2002, 2:73-85.
-
(2002)
Lancet Infect Dis
, vol.2
, pp. 73-85
-
-
Sanglard, D.1
Odds, F.C.2
-
37
-
-
84880324127
-
Caspofungin MICs correlate with treatment outcomes among patients with Candida glabrata invasive candidiasis and prior echinocandin exposure
-
Shields R.K., Nguyen M.H., Press E.G., Updike C.A., Clancy C.J. Caspofungin MICs correlate with treatment outcomes among patients with Candida glabrata invasive candidiasis and prior echinocandin exposure. Antimicrob Agents Chemother 2013, 57:3528-3535.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 3528-3535
-
-
Shields, R.K.1
Nguyen, M.H.2
Press, E.G.3
Updike, C.A.4
Clancy, C.J.5
-
38
-
-
70049109583
-
Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin
-
Singh S.D., Robbins N., Zaas A.K., Schell W.A., Perfect J.R., Cowen L.E. Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLoS Pathog 2009, 5:e1000532.
-
(2009)
PLoS Pathog
, vol.5
, pp. e1000532
-
-
Singh, S.D.1
Robbins, N.2
Zaas, A.K.3
Schell, W.A.4
Perfect, J.R.5
Cowen, L.E.6
-
39
-
-
79959192938
-
Disseminated candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin
-
Slater J.L., Howard S.J., Sharp A., Goodwin J., Gregson L.M., Alastruey-Izquierdo A., Arendrup M.C., Warn P.A., Perlin D.S., Hope W.W. Disseminated candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin. Antimicrob Agents Chemother 2011, 55:3075-3083.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 3075-3083
-
-
Slater, J.L.1
Howard, S.J.2
Sharp, A.3
Goodwin, J.4
Gregson, L.M.5
Alastruey-Izquierdo, A.6
Arendrup, M.C.7
Warn, P.A.8
Perlin, D.S.9
Hope, W.W.10
-
40
-
-
0036841830
-
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation
-
Smith W.L., Edlind T.D. Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. Antimicrob Agents Chemother 2002, 46:3532-3539.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3532-3539
-
-
Smith, W.L.1
Edlind, T.D.2
-
41
-
-
0034051227
-
Acetylation of histones and transcription-related factors
-
Sterner D.E., Berger S.L. Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 2000, 64:435-459.
-
(2000)
Microbiol Mol Biol Rev
, vol.64
, pp. 435-459
-
-
Sterner, D.E.1
Berger, S.L.2
|