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Volumn 97, Issue 9, 2016, Pages 2104-2116

Cross-protective potential of anti-nucleoprotein human monoclonal antibodies against lethal influenza A virus infection

Author keywords

Anti nucleoprotein monoclonal antibody; Antiviral effects; H1N1 influenza virus; H5N1 highly pathogenic avian influenza virus; Transgenic mouse

Indexed keywords

MONOCLONAL ANTIBODY; NUCLEOPROTEIN; CORE PROTEIN; IMMUNOLOGIC FACTOR; NP PROTEIN, INFLUENZA A VIRUS; RNA BINDING PROTEIN; VIRUS ANTIBODY;

EID: 84988874461     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/jgv.0.000518     Document Type: Article
Times cited : (30)

References (53)
  • 1
    • 0032810008 scopus 로고    scopus 로고
    • Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities
    • Armour, K. L., Clark, M. R., Hadley, A. G. & Williamson, L. M. (1999). Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities. Eur J Immunol 29, 2613-2624.
    • (1999) Eur J Immunol , vol.29 , pp. 2613-2624
    • Armour, K.L.1    Clark, M.R.2    Hadley, A.G.3    Williamson, L.M.4
  • 2
    • 0343049028 scopus 로고    scopus 로고
    • Several protein regions contribute to determine the nuclear and cytoplasmic localization of the influenza A virus nucleoprotein
    • Bullido, R., Gómez-Puertas, P., Albo, C. & Portela, A. (2000). Several protein regions contribute to determine the nuclear and cytoplasmic localization of the influenza A virus nucleoprotein. J Gen Virol 81, 135-142.
    • (2000) J Gen Virol , vol.81 , pp. 135-142
    • Bullido, R.1    Gómez-Puertas, P.2    Albo, C.3    Portela, A.4
  • 3
    • 0036719574 scopus 로고    scopus 로고
    • Antibodies, viruses and vaccines
    • Burton, D. R. (2002). Antibodies, viruses and vaccines. Nat Rev Immunol 2, 706-713.
    • (2002) Nat Rev Immunol , vol.2 , pp. 706-713
    • Burton, D.R.1
  • 4
    • 56149123448 scopus 로고    scopus 로고
    • A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza virus
    • Carragher, D. M., Kaminski, D. A., Moquin, A., Hartson, L. & Randall, T. D. (2008). A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza virus. J Immunol 181, 4168-4176.
    • (2008) J Immunol , vol.181 , pp. 4168-4176
    • Carragher, D.M.1    Kaminski, D.A.2    Moquin, A.3    Hartson, L.4    Randall, T.D.5
  • 5
    • 0002866386 scopus 로고    scopus 로고
    • Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses
    • Chen, W., Antón, L. C., Bennink, J. R. & Yewdell, J. W. (2000). Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses. Immunity 12, 83-93.
    • (2000) Immunity , vol.12 , pp. 83-93
    • Chen, W.1    Antón, L.C.2    Bennink, J.R.3    Yewdell, J.W.4
  • 6
    • 84926337506 scopus 로고    scopus 로고
    • Human monoclonal antibodies targeting the haemagglutinin glycoprotein can neutralize H7N9 influenza virus
    • & other authors
    • Chen, Z., Wang, J., Bao, L., Guo, L., Zhang, W., Xue, Y., Zhou, H., Xiao, Y., Wang, J. & other authors (2015). Human monoclonal antibodies targeting the haemagglutinin glycoprotein can neutralize H7N9 influenza virus. Nat Commun 6, 10.1038/ncomms7714.
    • (2015) Nat Commun , vol.6
    • Chen, Z.1    Wang, J.2    Bao, L.3    Guo, L.4    Zhang, W.5    Xue, Y.6    Zhou, H.7    Xiao, Y.8    Wang, J.9
  • 8
    • 27644544183 scopus 로고    scopus 로고
    • Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein
    • Epstein, S. L., Kong, W. P., Misplon, J. A., Lo, C. Y., Tumpey, T. M., Xu, L. & Nabel, G. J. (2005). Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine 23, 5404-5410.
    • (2005) Vaccine , vol.23 , pp. 5404-5410
    • Epstein, S.L.1    Kong, W.P.2    Misplon, J.A.3    Lo, C.Y.4    Tumpey, T.M.5    Xu, L.6    Nabel, G.J.7
  • 9
    • 0030999062 scopus 로고    scopus 로고
    • Protective cellular immunity: Cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization
    • Fu, T. M., Friedman, A., Ulmer, J. B., Liu, M. A. & Donnelly, J. J. (1997). Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization. J Virol 71, 2715-2721.
    • (1997) J Virol , vol.71 , pp. 2715-2721
    • Fu, T.M.1    Friedman, A.2    Ulmer, J.B.3    Liu, M.A.4    Donnelly, J.J.5
  • 10
    • 0033120964 scopus 로고    scopus 로고
    • Dose dependence of CTL precursor frequency induced by a DNA vaccine and correlation with protective immunity against influenza virus challenge
    • Fu, T. M., Guan, L., Friedman, A., Schofield, T. L., Ulmer, J. B., Liu, M. A. & Donnelly, J. J. (1999). Dose dependence of CTL precursor frequency induced by a DNA vaccine and correlation with protective immunity against influenza virus challenge. J Immunol 162, 4163-4170.
    • (1999) J Immunol , vol.162 , pp. 4163-4170
    • Fu, T.M.1    Guan, L.2    Friedman, A.3    Schofield, T.L.4    Ulmer, J.B.5    Liu, M.A.6    Donnelly, J.J.7
  • 11
    • 60349087488 scopus 로고    scopus 로고
    • Characterizations of four monoclonal antibodies against M2 protein ectodomain of influenza A virus
    • & other authors
    • Fu, T. M., Freed, D. C., Horton, M. S., Fan, J., Citron, M. P., Joyce, J. G., Garsky, V. M., Casimiro, D. R., Zhao, Q. & other authors (2009). Characterizations of four monoclonal antibodies against M2 protein ectodomain of influenza A virus. Virology 385, 218-226.
    • (2009) Virology , vol.385 , pp. 218-226
    • Fu, T.M.1    Freed, D.C.2    Horton, M.S.3    Fan, J.4    Citron, M.P.5    Joyce, J.G.6    Garsky, V.M.7    Casimiro, D.R.8    Zhao, Q.9
  • 12
    • 84888432018 scopus 로고    scopus 로고
    • Resistance to influenza A virus infection in transformed cell lines expressing an anti-PB2 monoclonal antibody
    • Fujimoto, Y., Ozaki, K., Maeda, M., Nishijima, K., Takakuwa, H., Otsuki, K., Kida, H. & Ono, E. (2013). Resistance to influenza A virus infection in transformed cell lines expressing an anti-PB2 monoclonal antibody. Vet J 198, 487-493.
    • (2013) Vet J , vol.198 , pp. 487-493
    • Fujimoto, Y.1    Ozaki, K.2    Maeda, M.3    Nishijima, K.4    Takakuwa, H.5    Otsuki, K.6    Kida, H.7    Ono, E.8
  • 13
  • 15
    • 0017728221 scopus 로고
    • Lymphocyte cytotoxicity to influenza virus-infected cells. II. Requirement for antibody and non-T lymphocytes
    • Greenberg, S. B., Criswell, B. S., Six, H. R. & Couch, R. B. (1977). Lymphocyte cytotoxicity to influenza virus-infected cells. II. Requirement for antibody and non-T lymphocytes. J Immunol 119, 2100-2106.
    • (1977) J Immunol , vol.119 , pp. 2100-2106
    • Greenberg, S.B.1    Criswell, B.S.2    Six, H.R.3    Couch, R.B.4
  • 16
    • 0018101480 scopus 로고
    • Lymphocyte cytotoxicity to influenza virus-infected cells: Response to vaccination and virus infection
    • Greenberg, S. B., Criswell, B. S., Six, H. R. & Couch, R. B. (1978). Lymphocyte cytotoxicity to influenza virus-infected cells: response to vaccination and virus infection. Infect Immun 20, 640-645.
    • (1978) Infect Immun , vol.20 , pp. 640-645
    • Greenberg, S.B.1    Criswell, B.S.2    Six, H.R.3    Couch, R.B.4
  • 17
    • 0021037896 scopus 로고
    • Antibody-dependent cell-mediated cytotoxicity against influenza virus-infected cells
    • Hashimoto, G., Wright, P. F. & Karzon, D. T. (1983a). Antibody-dependent cell-mediated cytotoxicity against influenza virus-infected cells. J Infect Dis 148, 785-794.
    • (1983) J Infect Dis , vol.148 , pp. 785-794
    • Hashimoto, G.1    Wright, P.F.2    Karzon, D.T.3
  • 18
    • 0020553944 scopus 로고
    • Ability of human cord blood lymphocytes to mediate antibody-dependent cellular cytotoxicity against influenza virus-infected cells
    • Hashimoto, G., Wright, P. F. & Karzon, D. T. (1983b). Ability of human cord blood lymphocytes to mediate antibody-dependent cellular cytotoxicity against influenza virus-infected cells. Infect Immun 42, 214-218.
    • (1983) Infect Immun , vol.42 , pp. 214-218
    • Hashimoto, G.1    Wright, P.F.2    Karzon, D.T.3
  • 19
    • 84880617786 scopus 로고    scopus 로고
    • In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies
    • Heaton, N. S., Leyva-Grado, V. H., Tan, G. S., Eggink, D., Hai, R. & Palese, P. (2013). In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. J Virol 87, 8272-8281.
    • (2013) J Virol , vol.87 , pp. 8272-8281
    • Heaton, N.S.1    Leyva-Grado, V.H.2    Tan, G.S.3    Eggink, D.4    Hai, R.5    Palese, P.6
  • 21
    • 0035559445 scopus 로고    scopus 로고
    • Universal primer set for the full-length amplification of all influenza A viruses
    • Hoffmann, E., Stech, J., Guan, Y., Webster, R. G. & Perez, D. R. (2001). Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol 146, 2275-2289.
    • (2001) Arch Virol , vol.146 , pp. 2275-2289
    • Hoffmann, E.1    Stech, J.2    Guan, Y.3    Webster, R.G.4    Perez, D.R.5
  • 23
    • 84888051249 scopus 로고    scopus 로고
    • Standard trivalent influenza virus protein vaccination does not prime antibody-dependent cellular cytotoxicity in macaques
    • & other authors
    • Jegaskanda, S., Amarasena, T. H., Laurie, K. L., Tan, H. X., Butler, J., Parsons, M. S., Alcantara, S., Petravic, J., Davenport, M. P. & other authors (2013a). Standard trivalent influenza virus protein vaccination does not prime antibody-dependent cellular cytotoxicity in macaques. J Virol 87, 13706-13718.
    • (2013) J Virol , vol.87 , pp. 13706-13718
    • Jegaskanda, S.1    Amarasena, T.H.2    Laurie, K.L.3    Tan, H.X.4    Butler, J.5    Parsons, M.S.6    Alcantara, S.7    Petravic, J.8    Davenport, M.P.9
  • 24
    • 84873547392 scopus 로고    scopus 로고
    • Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies
    • Jegaskanda, S., Job, E. R., Kramski, M., Laurie, K., Isitman, G., de Rose, R., Winnall, W. R., Stratov, I., Brooks, A. G. & other authors (2013b). Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies. J Immunol 190, 1837-1848.
    • (2013) J Immunol , vol.190 , pp. 1837-1848
    • Jegaskanda, S.1    Job, E.R.2    Kramski, M.3    Laurie, K.4    Isitman, G.5    De Rose, R.6    Winnall, W.R.7    Stratov, I.8    Brooks, A.G.9
  • 25
    • 84904263611 scopus 로고    scopus 로고
    • Influenza-specific antibody-dependent cellular cytotoxicity: Toward a universal influenza vaccine
    • Jegaskanda, S., Reading, P. C. & Kent, S. J. (2014). Influenza-specific antibody-dependent cellular cytotoxicity: toward a universal influenza vaccine. J Immunol 193, 469-475.
    • (2014) J Immunol , vol.193 , pp. 469-475
    • Jegaskanda, S.1    Reading, P.C.2    Kent, S.J.3
  • 27
    • 80155161545 scopus 로고    scopus 로고
    • Effect of three types of mixed anesthetic agents alternate to ketamine in mice
    • Kawai, S., Takagi, Y., Kaneko, S. & Kurosawa, T. (2011). Effect of three types of mixed anesthetic agents alternate to ketamine in mice. Exp Anim 60, 481-487.
    • (2011) Exp Anim , vol.60 , pp. 481-487
    • Kawai, S.1    Takagi, Y.2    Kaneko, S.3    Kurosawa, T.4
  • 28
    • 0035171964 scopus 로고    scopus 로고
    • Amino acids responsible for the absolute sialidase activity of the influenza A virus neuraminidase: Relationship to growth in the duck intestine
    • Kobasa, D., Wells, K. & Kawaoka, Y. (2001). Amino acids responsible for the absolute sialidase activity of the influenza A virus neuraminidase: relationship to growth in the duck intestine. J Virol 75, 11773-11780.
    • (2001) J Virol , vol.75 , pp. 11773-11780
    • Kobasa, D.1    Wells, K.2    Kawaoka, Y.3
  • 29
    • 79955042558 scopus 로고    scopus 로고
    • Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus
    • LaMere, M. W., Lam, H. T., Moquin, A., Haynes, L., Lund, F. E., Randall, T. D. & Kaminski, D. A. (2011). Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus. J Immunol 186, 4331-4339.
    • (2011) J Immunol , vol.186 , pp. 4331-4339
    • Lamere, M.W.1    Lam, H.T.2    Moquin, A.3    Haynes, L.4    Lund, F.E.5    Randall, T.D.6    Kaminski, D.A.7
  • 30
    • 0028898826 scopus 로고
    • A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia
    • McElroy, M. C., Pittet, J. F., Hashimoto, S., Allen, L., Wiener-Kronish, J. P. & Dobbs, L. G. (1995). A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia. Am J Physiol 268, L181-186.
    • (1995) Am J Physiol , vol.268
    • McElroy, M.C.1    Pittet, J.F.2    Hashimoto, S.3    Allen, L.4    Wiener-Kronish, J.P.5    Dobbs, L.G.6
  • 31
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa, H., Yamamura, K. & Miyazaki, J. (1991). Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193-199.
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 32
    • 79952409049 scopus 로고    scopus 로고
    • A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection
    • O’Brien, K. B., Morrison, T. E., Dundore, D. Y., Heise, M. T. & Schultz-Cherry, S. (2011). A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection. PLoS One 6, e17377.
    • (2011) Plos One , vol.6
    • O’Brien, K.B.1    Morrison, T.E.2    Dundore, D.Y.3    Heise, M.T.4    Schultz-Cherry, S.5
  • 33
    • 79951972609 scopus 로고    scopus 로고
    • Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza
    • Ohta, R., Torii, Y., Imai, M., Kimura, H., Okada, N. & Ito, Y. (2011). Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza. Microbiol Immunol 55, 191-198.
    • (2011) Microbiol Immunol , vol.55 , pp. 191-198
    • Ohta, R.1    Torii, Y.2    Imai, M.3    Kimura, H.4    Okada, N.5    Ito, Y.6
  • 34
    • 35048848924 scopus 로고    scopus 로고
    • Comparison of the antiviral potentials among the pseudorabies-resistant transgenes encoding different soluble forms of porcine nectin-1 in transgenic mice
    • Ono, E., Tomioka, Y., Watanabe, Y., Amagai, K., Morimatsu, M., Shinya, K. & Cherel, P. (2007). Comparison of the antiviral potentials among the pseudorabies-resistant transgenes encoding different soluble forms of porcine nectin-1 in transgenic mice. J Gen Virol 88, 2636-2641.
    • (2007) J Gen Virol , vol.88 , pp. 2636-2641
    • Ono, E.1    Tomioka, Y.2    Watanabe, Y.3    Amagai, K.4    Morimatsu, M.5    Shinya, K.6    Cherel, P.7
  • 36
    • 77949678181 scopus 로고    scopus 로고
    • Genomic signature and mutation trend analysis of pandemic (H1N1) 2009 influenza A virus
    • Pan, C., Cheung, B., Tan, S., Li, C., Li, L., Liu, S. & Jiang, S. (2010). Genomic signature and mutation trend analysis of pandemic (H1N1) 2009 influenza A virus. PLoS One 5, e9549.
    • (2010) Plos One , vol.5
    • Pan, C.1    Cheung, B.2    Tan, S.3    Li, C.4    Li, L.5    Liu, S.6    Jiang, S.7
  • 37
    • 0023759401 scopus 로고
    • The intracellular distribution of influenza virus matrix protein and nucleoprotein in infected cells and their relationship to haemagglutinin in the plasma membrane
    • Patterson, S., Gross, J. & Oxford, J. S. (1988). The intracellular distribution of influenza virus matrix protein and nucleoprotein in infected cells and their relationship to haemagglutinin in the plasma membrane. J Gen Virol 69, 1859-1872.
    • (1988) J Gen Virol , vol.69 , pp. 1859-1872
    • Patterson, S.1    Gross, J.2    Oxford, J.S.3
  • 38
    • 0025833701 scopus 로고
    • Localization of the influenza virus nucleoprotein: Cell-associated and extracellular non-virion forms
    • Prokudina, E. N. & Semenova, N. P. (1991). Localization of the influenza virus nucleoprotein: cell-associated and extracellular non-virion forms. J Gen Virol 72, 1699-1702.
    • (1991) J Gen Virol , vol.72 , pp. 1699-1702
    • Prokudina, E.N.1    Semenova, N.P.2
  • 40
    • 0025175893 scopus 로고
    • Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells
    • Rötzschke, O., Falk, K., Deres, K., Schild, H., Norda, M., Metzger, J., Jung, G. & Rammensee, H. G. (1990). Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells. Nature 348, 252-254.
    • (1990) Nature , vol.348 , pp. 252-254
    • Rötzschke, O.1    Falk, K.2    Deres, K.3    Schild, H.4    Norda, M.5    Metzger, J.6    Jung, G.7    Rammensee, H.G.8
  • 41
    • 0035794194 scopus 로고    scopus 로고
    • High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R
    • Shields, R. L., Namenuk, A. K., Hong, K., Meng, Y. G., Rae, J., Briggs, J., Xie, D., Lai, J., Stadlen, A. & other authors (2001). High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J Biol Chem 276, 6591-6604.
    • (2001) J Biol Chem , vol.276 , pp. 6591-6604
    • Shields, R.L.1    Namenuk, A.K.2    Hong, K.3    Meng, Y.G.4    Rae, J.5    Briggs, J.6    Xie, D.7    Lai, J.8    Stadlen, A.9
  • 42
    • 77951934871 scopus 로고    scopus 로고
    • Characterization of H5N1 highly pathogenic avian influenza virus isolated from a mountain hawk eagle in Japan
    • Shivakoti, S., Ito, H., Otsuki, K. & Ito, T. (2010). Characterization of H5N1 highly pathogenic avian influenza virus isolated from a mountain hawk eagle in Japan. J Vet Med Sci 72, 459-463.
    • (2010) J Vet Med Sci , vol.72 , pp. 459-463
    • Shivakoti, S.1    Ito, H.2    Otsuki, K.3    Ito, T.4
  • 43
    • 0027471186 scopus 로고
    • Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990
    • Shu, L. L., Bean, W. J. & Webster, R. G. (1993). Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990. J Virol 67, 2723-2729.
    • (1993) J Virol , vol.67 , pp. 2723-2729
    • Shu, L.L.1    Bean, W.J.2    Webster, R.G.3
  • 45
    • 78649476854 scopus 로고    scopus 로고
    • Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development
    • Staneková, Z. & Varečková, E. (2010). Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development. Virol J 7, 351.
    • (2010) Virol J , vol.7 , pp. 351
    • Staneková, Z.1    Varečková, E.2
  • 46
    • 0025338171 scopus 로고
    • Characterization and immunological properties of influenza A virus nucleoprotein (NP): Cell-associated NP isolated from infected cells or viral NP expressed by vaccinia recombinant virus do not confer protection
    • Stitz, L., Schmitz, C., Binder, D., Zinkernagel, R., Paoletti, E. & Becht, H. (1990). Characterization and immunological properties of influenza A virus nucleoprotein (NP): cell-associated NP isolated from infected cells or viral NP expressed by vaccinia recombinant virus do not confer protection. J Gen Virol 71, 1169-1179.
    • (1990) J Gen Virol , vol.71 , pp. 1169-1179
    • Stitz, L.1    Schmitz, C.2    Binder, D.3    Zinkernagel, R.4    Paoletti, E.5    Becht, H.6
  • 48
    • 84655163285 scopus 로고    scopus 로고
    • Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam
    • & other authors
    • Takakuwa, H., Yamashiro, T., Le, M. Q., Phuong, L. S., Ozaki, H., Tsunekuni, R., Usui, T., Ito, H., Morimatsu, M. & other authors (2012). Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam. Prev Vet Med 103, 192-200.
    • (2012) Prev Vet Med , vol.103 , pp. 192-200
    • Takakuwa, H.1    Yamashiro, T.2    Le, M.Q.3    Phuong, L.S.4    Ozaki, H.5    Tsunekuni, R.6    Usui, T.7    Ito, H.8    Morimatsu, M.9
  • 49
    • 84863597077 scopus 로고    scopus 로고
    • A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo
    • Tan, G. S., Krammer, F., Eggink, D., Kongchanagul, A., Moran, T. M. & Palese, P. (2012). A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. J Virol 86, 6179-6188.
    • (2012) J Virol , vol.86 , pp. 6179-6188
    • Tan, G.S.1    Krammer, F.2    Eggink, D.3    Kongchanagul, A.4    Moran, T.M.5    Palese, P.6
  • 51
    • 0017333509 scopus 로고
    • Early presence of ribonucleoprotein antigen on surface of influenza virus-infected cells
    • Virelizier, J. L., Allison, A. C., Oxford, J. S. & Schild, G. C. (1977). Early presence of ribonucleoprotein antigen on surface of influenza virus-infected cells. Nature 266, 52-54.
    • (1977) Nature , vol.266 , pp. 52-54
    • Virelizier, J.L.1    Allison, A.C.2    Oxford, J.S.3    Schild, G.C.4
  • 52
    • 77949442326 scopus 로고    scopus 로고
    • WHO, Geneva:World Health Organization. Available on line at
    • WHO (2009). Clinical features of severe cases of pandemic influenza. Geneva:World Health Organization. Available on line at http://www.who.int/csr/disease/swineflu/notes/h1n1_clinical_features_20091016/en/.
    • (2009) Clinical Features of Severe Cases of Pandemic Influenza
  • 53
    • 0019411535 scopus 로고
    • Expression of influenza A virus internal antigens on the surface of infected P815 cells
    • Yewdell, J. W., Frank, E. & Gerhard, W. (1981). Expression of influenza A virus internal antigens on the surface of infected P815 cells. J Immunol 126, 1814-1819.
    • (1981) J Immunol , vol.126 , pp. 1814-1819
    • Yewdell, J.W.1    Frank, E.2    Gerhard, W.3


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