Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress

Cell Research

Volumn 26, Issue 10, 2016, Pages 1112-1130

  Huang, De ^a   Li, Tingting ^a   Wang, Lin ^a   Zhang, Long ^a   Yan, Ronghui ^a   Li, Kui ^a   Xing, Songge ^a,b   Wu, Gongwei ^a   Hu, Lan ^a   Jia, Weidong ^b   Lin, Sheng Cai ^c   Dang, Chi V ^d   Song, Libing ^e   Gao, Ping ^a   Zhang, Huafeng ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b ANHUI PROVINCIAL HOSPITAL   (China)

^c XIAMEN UNIVERSITY   (China)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

AKT; AMPK; autophagy; HCC; ketone bodies; OXCT1

Indexed keywords

3-KETOACID COA-TRANSFERASE; COENZYME A TRANSFERASE; HYDROXYBUTYRIC ACID; KETONE BODY; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; TRANSCRIPTION FACTOR SP1;

ANALYSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOPHAGY; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; GLUCOSE BLOOD LEVEL; HEP-G2 CELL LINE; HUMAN; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MORTALITY; MOUSE; NUDE MOUSE; PATHOLOGY; PHARMACOLOGY; SERUM-FREE MEDIUM; SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; AUTOPHAGY; BLOOD GLUCOSE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; COENZYME A-TRANSFERASES; CULTURE MEDIA, SERUM-FREE; HEP G2 CELLS; HUMANS; HYDROXYBUTYRATES; KETONE BODIES; LIVER; LIVER NEOPLASMS; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 2; MICE; MICE, NUDE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TRANSPLANTATION, HETEROLOGOUS;

EID: 84988625351     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2016.109     Document Type: Article

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