Natural compound oblongifolin C inhibits autophagic flux, and induces apoptosis and mitochondrial dysfunction in human cholangiocarcinoma QBC939 cells

Molecular Medicine Reports

Volumn 14, Issue 4, 2016, Pages 3179-3183

  Zhang, Aiqing ^a   He, Wei ^b   Shi, Huimin ^a   Huang, Xiaodan ^a   Ji, Guozhong ^a  

^a THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Cholangiocarcinoma; Mitochondrial dysfunction; Oblongifolin C

Indexed keywords

OBLONGIFOLIN C; ANTINEOPLASTIC AGENT; TERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL VIABILITY; CHOLANGIOCARCINOMA CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; DRUG STRUCTURE; GARCINIA; GARCINIA YUNNANENSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; QBC939 CANCER CELL; WESTERN BLOTTING; BILE DUCT; BILE DUCT NEOPLASMS; CHEMISTRY; CHOLANGIOCARCINOMA; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; BILE DUCT NEOPLASMS; BILE DUCTS; CELL LINE, TUMOR; CHOLANGIOCARCINOMA; GARCINIA; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; TERPENES;

EID: 84988526194     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.5591     Document Type: Article

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