The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition

Gynecologic Oncology

Volumn 137, Issue 3, 2015, Pages 538-545

  Fukuda, Tomohiko ^a   Oda, Katsutoshi ^a   Wada Hiraike, Osamu ^a   Sone, Kenbun ^a   Inaba, Kanako ^a   Ikeda, Yuji ^a   Miyasaka, Aki ^a   Kashiyama, Tomoko ^a   Tanikawa, Michihiro ^a   Arimoto, Takahide ^a   Kuramoto, Hiroyuki ^b   Yano, Tetsu ^c   Kawana, Kei ^a   Osuga, Yutaka ^a   Fujii, Tomoyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Kanagawa Health Service Association   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Autophagy; Chemosensitivity; Chloroquine; Cisplatin; Endometrial cancer

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; CHLOROQUINE; CISPLATIN; DOXORUBICIN; LIGHT CHAIN 3; PROTEIN; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ATG5 GENE; ATG7 GENE; AUTOPHAGY; CANCER RESISTANCE; CELL CYCLE ASSAY; CELL PROLIFERATION ASSAY; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOMETRIAL CANCER CELL LINE; ENDOMETRIUM CANCER; FEMALE; GENE; GENE SILENCING; HUMAN; HUMAN CELL; MTT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR PROMOTION; UPREGULATION; WESTERN BLOTTING; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; DRUG EFFECTS; DRUG POTENTIATION; DRUG RESISTANCE; ENDOMETRIAL NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ANTIMALARIALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; AUTOPHAGY; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHLOROQUINE; CISPLATIN; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS;

EID: 84930042487     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2015.03.053     Document Type: Article

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