Xanthorrhizol, a natural sesquiterpenoid, induces apoptosis and growth arrest in HCT116 human colon cancer cells

Journal of Pharmacological Sciences

Volumn 111, Issue 3, 2009, Pages 276-284

  Kang, You Jin ^a   Park, Kwang Kyun ^b   Chung, Won Yoon ^b   Hwang, Jae Kwan ^c   Lee, Sang Kook ^a  

^a Ewha Womans University   (South Korea)

^b Yonsei University College of Dentistry   (South Korea)

^c Yonsei University   (South Korea)

Author keywords

Apoptosis; Cell cycle arrest; HCT116 human colon cancer cell; Non steroidal anti inflammatory drug activated gene 1 (NAG 1) expression; Xanthorrhizol

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN A; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P21; PROTEIN P27; SESQUITERPENOID; UNCLASSIFIED DRUG; XANTHORRHIZOL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; CURCUMA LONGA; CURCUMA XANTHORRHIZA; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; NONHUMAN; NONSTEROIDAL ANTIINFLAMMATORY DRUG ACTIVATED GENE 1; PROTEIN EXPRESSION;

EID: 73349083967     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09141FP     Document Type: Article

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