Chloroquine potentiates the anti-cancer effect of lidamycin on non-small cell lung cancer cells in vitro

Acta Pharmacologica Sinica

Volumn 35, Issue 5, 2014, Pages 645-652

  Liu, Fang ^a   Shang, Yue ^a   Chen, Shu Zhen ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

anticancer drug; apoptosis; autophagy; chloroquine; drug interaction; lidamycin; lung cancer; synergism

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CELL PROTEIN; CHLOROQUINE; LIDAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN LC3 I; PROTEIN LC3 II; PROTEIN P53; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; ANTIBIOTIC C 1027; ENEDIYNE; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN BAX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL PROLIFERATION; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MOUSE; MTT ASSAY; NON SMALL CELL LUNG CANCER; NONHUMAN; NUDE MOUSE; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, NON-SMALL-CELL LUNG; DRUG EFFECTS; LUNG NEOPLASMS; METABOLISM; TUMOR CELL LINE;

AMINOGLYCOSIDES; ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 3; CELL LINE, TUMOR; CHLOROQUINE; DRUG SYNERGISM; ENEDIYNES; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84927173417     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2014.3     Document Type: Article

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