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Volumn 48, Issue 14, 2011, Pages 1611-1620

Complement factor I in health and disease

Author keywords

Complement system; Factor I

Indexed keywords

COMPLEMENT FACTOR I; COMPLEMENT MEMBRANE ATTACK COMPLEX; LOW DENSITY LIPOPROTEIN; SERINE PROTEINASE;

EID: 79960446438     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.04.004     Document Type: Review
Times cited : (130)

References (95)
  • 2
    • 0026077255 scopus 로고
    • Contribution of the repeating domains of membrane cofactor protein (CD46) of the complement system to ligand binding and cofactor activity
    • Adams E.M., Brown M.C., Nunge M., Krych M., Atkinson J.P. Contribution of the repeating domains of membrane cofactor protein (CD46) of the complement system to ligand binding and cofactor activity. J. Immunol. 1991, 147:3005-3011.
    • (1991) J. Immunol. , vol.147 , pp. 3005-3011
    • Adams, E.M.1    Brown, M.C.2    Nunge, M.3    Krych, M.4    Atkinson, J.P.5
  • 3
    • 0034969065 scopus 로고    scopus 로고
    • Inherited complete factor I deficiency associated with systemic lupus erythematosus, higher susceptibility to infection and low levels of factor H
    • Amadei N., Baracho G.V., Nudelman V., Bastos W., Florido M.P., Isaac L. Inherited complete factor I deficiency associated with systemic lupus erythematosus, higher susceptibility to infection and low levels of factor H. Scand. J. Immunol. 2001, 53:615-621.
    • (2001) Scand. J. Immunol. , vol.53 , pp. 615-621
    • Amadei, N.1    Baracho, G.V.2    Nudelman, V.3    Bastos, W.4    Florido, M.P.5    Isaac, L.6
  • 4
    • 0037318443 scopus 로고    scopus 로고
    • Molecular characterization of homozygous hereditary factor I deficiency
    • Baracho G.V., Nudelman V., Isaac L. Molecular characterization of homozygous hereditary factor I deficiency. Clin. Exp. Immunol. 2003, 131:280-286.
    • (2003) Clin. Exp. Immunol. , vol.131 , pp. 280-286
    • Baracho, G.V.1    Nudelman, V.2    Isaac, L.3
  • 6
    • 0035920160 scopus 로고    scopus 로고
    • Structural requirements for the complement regulatory activities of C4BP
    • Blom A.M., Kask L., Dahlback B. Structural requirements for the complement regulatory activities of C4BP. J. Biol. Chem. 2001, 276:27136-27144.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27136-27144
    • Blom, A.M.1    Kask, L.2    Dahlback, B.3
  • 7
    • 0037210218 scopus 로고    scopus 로고
    • CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b
    • Blom A.M., Kask L., Dahlback B. CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b. Mol. Immunol. 2003, 39:547-556.
    • (2003) Mol. Immunol. , vol.39 , pp. 547-556
    • Blom, A.M.1    Kask, L.2    Dahlback, B.3
  • 8
    • 84934438604 scopus 로고    scopus 로고
    • Viral heparin-binding complement inhibitors-a recurring theme
    • Blom A.M., Mark L., Spiller O.B. Viral heparin-binding complement inhibitors-a recurring theme. Adv. Exp. Med. Biol. 2007, 598:105-125.
    • (2007) Adv. Exp. Med. Biol. , vol.598 , pp. 105-125
    • Blom, A.M.1    Mark, L.2    Spiller, O.B.3
  • 9
    • 37549036284 scopus 로고    scopus 로고
    • Endothelial cells are a target of both complement and kinin system
    • Bossi F., Bulla R., Tedesco F. Endothelial cells are a target of both complement and kinin system. Int. Immunopharmacol. 2008, 8:143-147.
    • (2008) Int. Immunopharmacol. , vol.8 , pp. 143-147
    • Bossi, F.1    Bulla, R.2    Tedesco, F.3
  • 12
    • 0023105043 scopus 로고
    • Characterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones
    • Catterall C.F., Lyons A., Sim R.B., Day A.J., Harris T.J. Characterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones. Biochem. J. 1987, 242:849-856.
    • (1987) Biochem. J. , vol.242 , pp. 849-856
    • Catterall, C.F.1    Lyons, A.2    Sim, R.B.3    Day, A.J.4    Harris, T.J.5
  • 13
    • 0032491212 scopus 로고    scopus 로고
    • Possible arrangement of the five domains in human complement factor I as determined by a combination of X-ray and neutron scattering and homology modeling
    • Chamberlain D., Ullman C.G., Perkins S.J. Possible arrangement of the five domains in human complement factor I as determined by a combination of X-ray and neutron scattering and homology modeling. Biochemistry 1998, 37:13918-13929.
    • (1998) Biochemistry , vol.37 , pp. 13918-13929
    • Chamberlain, D.1    Ullman, C.G.2    Perkins, S.J.3
  • 15
    • 0019755873 scopus 로고
    • C3b inactivator and beta 1H
    • Crossley L.G. C3b inactivator and beta 1H. Methods Enzymol. 1981, 80:112-124.
    • (1981) Methods Enzymol. , vol.80 , pp. 112-124
    • Crossley, L.G.1
  • 17
    • 0026645955 scopus 로고
    • Ultrastructures and interactions of complement factors H and I
    • DiScipio R.G. Ultrastructures and interactions of complement factors H and I. J. Immunol. 1992, 149:2592-2599.
    • (1992) J. Immunol. , vol.149 , pp. 2592-2599
    • DiScipio, R.G.1
  • 18
    • 67650508077 scopus 로고    scopus 로고
    • The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome
    • Dragon-Durey M.A., Blanc C., Marliot F., Loirat C., Blouin J., Sautes-Fridman C., Fridman W.H., Fremeaux-Bacchi V. The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome. J. Med. Genet. 2009, 46:447-450.
    • (2009) J. Med. Genet. , vol.46 , pp. 447-450
    • Dragon-Durey, M.A.1    Blanc, C.2    Marliot, F.3    Loirat, C.4    Blouin, J.5    Sautes-Fridman, C.6    Fridman, W.H.7    Fremeaux-Bacchi, V.8
  • 19
    • 0025370167 scopus 로고
    • Inhibition of factor I by diisopropylfluorophosphate. Evidence of conformational changes in factor I induced by C3b and additional studies on the specificity of factor I
    • Ekdahl K.N., Nilsson U.R., Nilsson B. Inhibition of factor I by diisopropylfluorophosphate. Evidence of conformational changes in factor I induced by C3b and additional studies on the specificity of factor I. J. Immunol. 1990, 144:4269-4274.
    • (1990) J. Immunol. , vol.144 , pp. 4269-4274
    • Ekdahl, K.N.1    Nilsson, U.R.2    Nilsson, B.3
  • 23
    • 0017665846 scopus 로고
    • Purification of C3b inactivator and demonstration of its two polypeptide chain structure
    • Fearon D.T. Purification of C3b inactivator and demonstration of its two polypeptide chain structure. J. Immunol. 1977, 119:1248-1252.
    • (1977) J. Immunol. , vol.119 , pp. 1248-1252
    • Fearon, D.T.1
  • 24
    • 0032477690 scopus 로고    scopus 로고
    • Rational design of boropeptide thrombin inhibitors: beta, beta-dialkyl-phenethylglycine P2 analogs of DuP 714 with greater selectivity over complement factor I and an improved safety profile
    • Fevig J.M., Buriak J., Cacciola J., Alexander R.S., Kettner C.A., Knabb R.M., Pruitt J.R., Weber P.C., Wexler R.R. Rational design of boropeptide thrombin inhibitors: beta, beta-dialkyl-phenethylglycine P2 analogs of DuP 714 with greater selectivity over complement factor I and an improved safety profile. Bioorg. Med. Chem. Lett. 1998, 8:301-306.
    • (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 301-306
    • Fevig, J.M.1    Buriak, J.2    Cacciola, J.3    Alexander, R.S.4    Kettner, C.A.5    Knabb, R.M.6    Pruitt, J.R.7    Weber, P.C.8    Wexler, R.R.9
  • 29
    • 24644456929 scopus 로고    scopus 로고
    • Complement factor I deficiency associated with recurrent infections, vasculitis and immune complex glomerulonephritis
    • Genel F., Sjoholm A.G., Skattum L., Truedsson L. Complement factor I deficiency associated with recurrent infections, vasculitis and immune complex glomerulonephritis. Scand. J. Infect. Dis. 2005, 37:615-618.
    • (2005) Scand. J. Infect. Dis. , vol.37 , pp. 615-618
    • Genel, F.1    Sjoholm, A.G.2    Skattum, L.3    Truedsson, L.4
  • 31
    • 0021164865 scopus 로고
    • Biosynthesis and postsynthetic processing of human C3b/C4b inactivator (factor I) in three hepatoma cell lines
    • Goldberger G., Arnaout M.A., Aden D., Kay R., Rits M., Colten H.R. Biosynthesis and postsynthetic processing of human C3b/C4b inactivator (factor I) in three hepatoma cell lines. J. Biol. Chem. 1984, 259:6492-6497.
    • (1984) J. Biol. Chem. , vol.259 , pp. 6492-6497
    • Goldberger, G.1    Arnaout, M.A.2    Aden, D.3    Kay, R.4    Rits, M.5    Colten, H.R.6
  • 32
    • 0023250642 scopus 로고
    • Human complement factor I: analysis of cDNA-derived primary structure and assignment of its gene to chromosome 4
    • Goldberger G., Bruns G.A., Rits M., Edge M.D., Kwiatkowski D.J. Human complement factor I: analysis of cDNA-derived primary structure and assignment of its gene to chromosome 4. J. Biol. Chem. 1987, 262:10065-10071.
    • (1987) J. Biol. Chem. , vol.262 , pp. 10065-10071
    • Goldberger, G.1    Bruns, G.A.2    Rits, M.3    Edge, M.D.4    Kwiatkowski, D.J.5
  • 34
    • 0020577177 scopus 로고
    • Conformational changes accompanying proteolytic cleavage of human complement protein C3b by the regulatory enzyme factor I and its cofactor H. Spectroscopic and enzymological studies
    • Isenman D.E. Conformational changes accompanying proteolytic cleavage of human complement protein C3b by the regulatory enzyme factor I and its cofactor H. Spectroscopic and enzymological studies. J. Biol. Chem. 1983, 258:4238-4244.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4238-4244
    • Isenman, D.E.1
  • 35
    • 33750859976 scopus 로고    scopus 로고
    • Structure of C3b reveals conformational changes that underlie complement activity
    • Janssen B.J., Christodoulidou A., McCarthy A., Lambris J.D., Gros P. Structure of C3b reveals conformational changes that underlie complement activity. Nature 2006, 444:213-216.
    • (2006) Nature , vol.444 , pp. 213-216
    • Janssen, B.J.1    Christodoulidou, A.2    McCarthy, A.3    Lambris, J.D.4    Gros, P.5
  • 40
    • 0032502792 scopus 로고    scopus 로고
    • Structure-function analysis of the active sites of complement receptor type 1
    • Krych M., Hauhart R., Atkinson J.P. Structure-function analysis of the active sites of complement receptor type 1. J. Biol. Chem. 1998, 273:8623-8629.
    • (1998) J. Biol. Chem. , vol.273 , pp. 8623-8629
    • Krych, M.1    Hauhart, R.2    Atkinson, J.P.3
  • 41
    • 0014276833 scopus 로고
    • The demonstration in human serum of " conglutinogen-activating factor" and its effect on the third component of complement
    • Lachmann P.J., Muller-Eberhard H.J. The demonstration in human serum of " conglutinogen-activating factor" and its effect on the third component of complement. J. Immunol. 1968, 100:691-698.
    • (1968) J. Immunol. , vol.100 , pp. 691-698
    • Lachmann, P.J.1    Muller-Eberhard, H.J.2
  • 44
    • 77957577058 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome associated with mutations in complement regulator genes
    • Le Quintrec M., Roumenina L., Noris M., Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome associated with mutations in complement regulator genes. Semin. Thromb. Hemost. 2010, 36:641-652.
    • (2010) Semin. Thromb. Hemost. , vol.36 , pp. 641-652
    • Le Quintrec, M.1    Roumenina, L.2    Noris, M.3    Fremeaux-Bacchi, V.4
  • 46
    • 77952682366 scopus 로고    scopus 로고
    • Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome
    • Maga T.K., Nishimura C.J., Weaver A.E., Frees K.L., Smith R.J. Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. Hum. Mutat. 2010, 31:E1445-E1460.
    • (2010) Hum. Mutat. , vol.31
    • Maga, T.K.1    Nishimura, C.J.2    Weaver, A.E.3    Frees, K.L.4    Smith, R.J.5
  • 47
    • 79960453262 scopus 로고    scopus 로고
    • Expression and characterization of the serine protease domain of human complement components
    • Malhotra R., Priest R., McDowell W., Telaranta A., Hood C. Expression and characterization of the serine protease domain of human complement components. Inflamm. Res. 2003, 52:S165.
    • (2003) Inflamm. Res. , vol.52
    • Malhotra, R.1    Priest, R.2    McDowell, W.3    Telaranta, A.4    Hood, C.5
  • 48
    • 34548849117 scopus 로고    scopus 로고
    • The role of complement in inflammatory diseases from behind the scenes into the spotlight
    • Markiewski M.M., Lambris J.D. The role of complement in inflammatory diseases from behind the scenes into the spotlight. Am. J. Pathol. 2007, 171:715-727.
    • (2007) Am. J. Pathol. , vol.171 , pp. 715-727
    • Markiewski, M.M.1    Lambris, J.D.2
  • 49
    • 0032497788 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional regulation of complement factor I (CFI) gene expression in Hep G2 cells by interleukin-6
    • Minta J.O., Fung M., Paramaswara B. Transcriptional and post-transcriptional regulation of complement factor I (CFI) gene expression in Hep G2 cells by interleukin-6. Biochim. Biophys. Acta 1998, 1442:286-295.
    • (1998) Biochim. Biophys. Acta , vol.1442 , pp. 286-295
    • Minta, J.O.1    Fung, M.2    Paramaswara, B.3
  • 52
    • 0019992119 scopus 로고
    • Complement biosynthesis by the human hepatoma-derived cell line HepG2
    • Morris K.M., Aden D.P., Knowles B.B., Colten H.R. Complement biosynthesis by the human hepatoma-derived cell line HepG2. J. Clin. Invest. 1982, 70:906-913.
    • (1982) J. Clin. Invest. , vol.70 , pp. 906-913
    • Morris, K.M.1    Aden, D.P.2    Knowles, B.B.3    Colten, H.R.4
  • 53
    • 74249114451 scopus 로고    scopus 로고
    • Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I
    • Nilsson S.C., Kalchishkova N., Trouw L.A., Fremeaux-Bacchi V., Villoutreix B.O., Blom A.M. Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I. Eur. J. Immunol. 2010, 40:172-185.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 172-185
    • Nilsson, S.C.1    Kalchishkova, N.2    Trouw, L.A.3    Fremeaux-Bacchi, V.4    Villoutreix, B.O.5    Blom, A.M.6
  • 56
    • 79952446417 scopus 로고    scopus 로고
    • Molecular characterization of two novel cases of complete complement inhibitor factor I deficiency
    • Nita I.M., Genel F., Nilsson S.C., Smart J., Truedsson L., Choo S., Blom A.M. Molecular characterization of two novel cases of complete complement inhibitor factor I deficiency. Mol. Immunol. 2011, 48:1068-1072.
    • (2011) Mol. Immunol. , vol.48 , pp. 1068-1072
    • Nita, I.M.1    Genel, F.2    Nilsson, S.C.3    Smart, J.4    Truedsson, L.5    Choo, S.6    Blom, A.M.7
  • 58
    • 34548288545 scopus 로고    scopus 로고
    • Non-small cell lung cancer cells produce a functional set of complement factor I and its soluble cofactors
    • Okroj M., Hsu Y.F., Ajona D., Pio R., Blom A.M. Non-small cell lung cancer cells produce a functional set of complement factor I and its soluble cofactors. Mol. Immunol. 2008, 45:169-179.
    • (2008) Mol. Immunol. , vol.45 , pp. 169-179
    • Okroj, M.1    Hsu, Y.F.2    Ajona, D.3    Pio, R.4    Blom, A.M.5
  • 59
    • 0020684529 scopus 로고
    • Kinetic and thermodynamic analysis of the control of C3b by the complement regulatory proteins factors H and I
    • Pangburn M.K., Muller-Eberhard H.J. Kinetic and thermodynamic analysis of the control of C3b by the complement regulatory proteins factors H and I. Biochemistry 1983, 22:178-185.
    • (1983) Biochemistry , vol.22 , pp. 178-185
    • Pangburn, M.K.1    Muller-Eberhard, H.J.2
  • 60
    • 0032817319 scopus 로고    scopus 로고
    • An initiator element and a proximal cis-acting sequence are essential for transcriptional activation of the complement factor I (CFI) gene
    • Paramaswara B., Minta J.O. An initiator element and a proximal cis-acting sequence are essential for transcriptional activation of the complement factor I (CFI) gene. Gene 1999, 237:71-80.
    • (1999) Gene , vol.237 , pp. 71-80
    • Paramaswara, B.1    Minta, J.O.2
  • 62
    • 0020613041 scopus 로고
    • Human platelet activation by C3a and C3a des-arg
    • Polley M.J., Nachman R.L. Human platelet activation by C3a and C3a des-arg. J. Exp. Med. 1983, 158:603-615.
    • (1983) J. Exp. Med. , vol.158 , pp. 603-615
    • Polley, M.J.1    Nachman, R.L.2
  • 66
    • 0030679694 scopus 로고    scopus 로고
    • Selection of S18326 as a new potent and selective boronic acid direct thrombin inhibitor
    • Rupin A., Mennecier P., Lila C., de Nanteuil G., Verbeuren T.J. Selection of S18326 as a new potent and selective boronic acid direct thrombin inhibitor. Thromb. Haemost. 1997, 78:1221-1227.
    • (1997) Thromb. Haemost. , vol.78 , pp. 1221-1227
    • Rupin, A.1    Mennecier, P.2    Lila, C.3    de Nanteuil, G.4    Verbeuren, T.J.5
  • 67
    • 0028881851 scopus 로고
    • Complement-mediated regulation of tissue factor activity in endothelium
    • Saadi S., Holzknecht R.A., Patte C.P., Stern D.M., Platt J.L. Complement-mediated regulation of tissue factor activity in endothelium. J. Exp. Med. 1995, 182:1807-1814.
    • (1995) J. Exp. Med. , vol.182 , pp. 1807-1814
    • Saadi, S.1    Holzknecht, R.A.2    Patte, C.P.3    Stern, D.M.4    Platt, J.L.5
  • 72
    • 0021910179 scopus 로고
    • Limited proteolysis of complement protein C3b by regulatory enzyme C3b inactivator: isolation and characterization of a biologically active fragment C3d,g
    • Seya T., Nagasawa S. Limited proteolysis of complement protein C3b by regulatory enzyme C3b inactivator: isolation and characterization of a biologically active fragment C3d,g. J. Biochem. 1985, 97:373-382.
    • (1985) J. Biochem. , vol.97 , pp. 373-382
    • Seya, T.1    Nagasawa, S.2
  • 73
    • 0028924417 scopus 로고
    • Human factor H and C4b-binding protein serve as factor I-cofactors both encompassing inactivation of C3b and C4b
    • Seya T., Nakamura K., Masaki T., Ichihara-Itoh C., Matsumoto M., Nagasawa S. Human factor H and C4b-binding protein serve as factor I-cofactors both encompassing inactivation of C3b and C4b. Mol. Immunol. 1995, 32:355-360.
    • (1995) Mol. Immunol. , vol.32 , pp. 355-360
    • Seya, T.1    Nakamura, K.2    Masaki, T.3    Ichihara-Itoh, C.4    Matsumoto, M.5    Nagasawa, S.6
  • 75
    • 0019776981 scopus 로고
    • Pattern of degradation of human complement fragment C3b
    • Sim E., Wood A.B., Hsiung L.M., Sim R.B. Pattern of degradation of human complement fragment C3b. FEBS Lett. 1981, 132:55-60.
    • (1981) FEBS Lett. , vol.132 , pp. 55-60
    • Sim, E.1    Wood, A.B.2    Hsiung, L.M.3    Sim, R.B.4
  • 76
    • 0027377724 scopus 로고
    • Complement factor I and cofactors in control of complement system convertase enzymes
    • Sim R.B., Day A.J., Moffatt B.E., Fontaine M. Complement factor I and cofactors in control of complement system convertase enzymes. Methods Enzymol. 1993, 223:13-35.
    • (1993) Methods Enzymol. , vol.223 , pp. 13-35
    • Sim, R.B.1    Day, A.J.2    Moffatt, B.E.3    Fontaine, M.4
  • 77
    • 60349127531 scopus 로고    scopus 로고
    • Complement activation and inhibition: a delicate balance
    • Sjoberg A.P., Trouw L.A., Blom A.M. Complement activation and inhibition: a delicate balance. Trends Immunol. 2009, 30:83-90.
    • (2009) Trends Immunol. , vol.30 , pp. 83-90
    • Sjoberg, A.P.1    Trouw, L.A.2    Blom, A.M.3
  • 78
    • 0030773223 scopus 로고    scopus 로고
    • Interactions between human complement components factor H, factor I and C3b
    • Soames C.J., Sim R.B. Interactions between human complement components factor H, factor I and C3b. Biochem. J. 1997, 326(Pt 2):553-561.
    • (1997) Biochem. J. , vol.326 , Issue.PART 2 , pp. 553-561
    • Soames, C.J.1    Sim, R.B.2
  • 79
    • 0031010642 scopus 로고    scopus 로고
    • The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity
    • Tedesco F., Pausa M., Nardon E., Introna M., Mantovani A., Dobrina A. The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity. J. Exp. Med. 1997, 185:1619-1627.
    • (1997) J. Exp. Med. , vol.185 , pp. 1619-1627
    • Tedesco, F.1    Pausa, M.2    Nardon, E.3    Introna, M.4    Mantovani, A.5    Dobrina, A.6
  • 80
    • 4644327017 scopus 로고    scopus 로고
    • Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5
    • Thai C.T., Ogata R.T. Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5. J. Immunol. 2004, 173:4547-4552.
    • (2004) J. Immunol. , vol.173 , pp. 4547-4552
    • Thai, C.T.1    Ogata, R.T.2
  • 81
  • 82
    • 2942709791 scopus 로고    scopus 로고
    • Human complement factor I does not require cofactors for cleavage of synthetic substrates
    • Tsiftsoglou S.A., Sim R.B. Human complement factor I does not require cofactors for cleavage of synthetic substrates. J. Immunol. 2004, 173:367-375.
    • (2004) J. Immunol. , vol.173 , pp. 367-375
    • Tsiftsoglou, S.A.1    Sim, R.B.2
  • 84
    • 0031784286 scopus 로고    scopus 로고
    • Human complement factor I: its expression by insect cells and its biochemical and structural characterisation
    • Ullman C.G., Chamberlain D., Ansari A., Emery V.C., Haris P.I., Sim R.B., Perkins S.J. Human complement factor I: its expression by insect cells and its biochemical and structural characterisation. Mol. Immunol. 1998, 35:503-512.
    • (1998) Mol. Immunol. , vol.35 , pp. 503-512
    • Ullman, C.G.1    Chamberlain, D.2    Ansari, A.3    Emery, V.C.4    Haris, P.I.5    Sim, R.B.6    Perkins, S.J.7
  • 85
    • 0030770324 scopus 로고    scopus 로고
    • The factor I and follistatin domain families: the return of a prodigal son
    • Ullman C.G., Perkins S.J. The factor I and follistatin domain families: the return of a prodigal son. Biochem. J. 1997, 326:939-941.
    • (1997) Biochem. J. , vol.326 , pp. 939-941
    • Ullman, C.G.1    Perkins, S.J.2
  • 86
    • 0028037085 scopus 로고
    • The organization of the human complement factor I gene (IF): a member of the serine protease gene family
    • Vyse T.J., Bates G.P., Walport M.J., Morley B.J. The organization of the human complement factor I gene (IF): a member of the serine protease gene family. Genomics 1994, 24:90-98.
    • (1994) Genomics , vol.24 , pp. 90-98
    • Vyse, T.J.1    Bates, G.P.2    Walport, M.J.3    Morley, B.J.4
  • 88
    • 67649389597 scopus 로고    scopus 로고
    • Renal disease associated with inherited disorders of the complement system
    • Welch T.R., Blystone L.W. Renal disease associated with inherited disorders of the complement system. Pediatr. Nephrol. 2009, 24:1439-1444.
    • (2009) Pediatr. Nephrol. , vol.24 , pp. 1439-1444
    • Welch, T.R.1    Blystone, L.W.2
  • 90
    • 0018864029 scopus 로고
    • Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes
    • Whaley K. Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes. J. Exp. Med. 1980, 151:501-516.
    • (1980) J. Exp. Med. , vol.151 , pp. 501-516
    • Whaley, K.1
  • 92
    • 0028904950 scopus 로고
    • Processing of human factor I in COS-1 cells co-transfected with factor I and paired basic amino acid cleaving enzyme (PACE) cDNA
    • Wong M.J., Goldberger G., Isenman D.E., Minta J.O. Processing of human factor I in COS-1 cells co-transfected with factor I and paired basic amino acid cleaving enzyme (PACE) cDNA. Mol. Immunol. 1995, 32:379-387.
    • (1995) Mol. Immunol. , vol.32 , pp. 379-387
    • Wong, M.J.1    Goldberger, G.2    Isenman, D.E.3    Minta, J.O.4
  • 93
    • 0036387145 scopus 로고    scopus 로고
    • Nonpeptide factor Xa inhibitors: DPC423, a highly potent and orally bioavailable pyrazole antithrombotic agent
    • Wong P.C., Pinto D.J., Knabb R.M. Nonpeptide factor Xa inhibitors: DPC423, a highly potent and orally bioavailable pyrazole antithrombotic agent. Cardiovasc. Drug. Rev. 2002, 20:137-152.
    • (2002) Cardiovasc. Drug. Rev. , vol.20 , pp. 137-152
    • Wong, P.C.1    Pinto, D.J.2    Knabb, R.M.3
  • 94
    • 67649230210 scopus 로고    scopus 로고
    • Structure of complement fragment C3b-factor H and implications for host protection by complement regulators
    • Wu J., Wu Y.Q., Ricklin D., Janssen B.J., Lambris J.D., Gros P. Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat. Immunol. 2009, 10:728-733.
    • (2009) Nat. Immunol. , vol.10 , pp. 728-733
    • Wu, J.1    Wu, Y.Q.2    Ricklin, D.3    Janssen, B.J.4    Lambris, J.D.5    Gros, P.6


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